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ArticlesPeer ReviewedFull Text
Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): a multicentre, open-label, phase 2 randomised controlled trial
Author / Creator:Fehrenbacher, Louis, Dr ; Spira, Alexander, MD ; Ballinger, Marcus, PhD ; Kowanetz, Marcin, PhD ; Vansteenkiste, Johan, Prof ; Mazieres, Julien, Prof ; Park, Keunchil, Prof ; Smith, David, MD ; Artal-Cortes, Angel, MD ; Lewanski, Conrad, MD ; Braiteh, Fadi, MD ; Waterkamp, Daniel, MD ; He, Pei, PhD ; Zou, Wei, PhD ; Chen, Daniel S, MD ; Yi, Jing, PhD ; Sandler, Alan, MD ; Rittmeyer, Achim, MD
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2016-04, Vol.387 (10030), p.1837-1846
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iRECIST: guidelines for response criteria for use in trials testing immunotherapeutics
Author / Creator:Seymour, Lesley, Prof ; Bogaerts, Jan, PhD ; Perrone, Andrea, MD ; Ford, Robert, MD ; Schwartz, Lawrence H, Prof ; Mandrekar, Sumithra, Prof ; Lin, Nancy U, MD ; Litière, Saskia, PhD ; Dancey, Janet, Prof ; Chen, Alice, MD ; Hodi, F Stephen, Prof ; Therasse, Patrick, MD ; Hoekstra, Otto S, Prof ; Shankar, Lalitha K, MD ; Wolchok, Jedd D, MD ; Ballinger, Marcus, PhD ; Caramella, Caroline, MD ; de Vries, Elisabeth G E, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2017-03, Vol.18 (3), p.e143-e152
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Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): a phase 3, open-label, multicentre randomised controlled trial
Author / Creator:Rittmeyer, Achim, MD ; Barlesi, Fabrice, PhD ; Waterkamp, Daniel, MD ; Park, Keunchil, MD ; Ciardiello, Fortunato, MD ; von Pawel, Joachim, MD ; Gadgeel, Shirish M, MD ; Hida, Toyoaki, PhD ; Kowalski, Dariusz M, PhD ; Dols, Manuel Cobo, MD ; Cortinovis, Diego L, PhD ; Leach, Joseph, MD ; Polikoff, Jonathan, MD ; Barrios, Carlos, MD ; Kabbinavar, Fairooz, MD ; Frontera, Osvaldo Arén, MD ; De Marinis, Filippo, MD ; Turna, Hande, MD ; Lee, Jong-Seok, MD ; Ballinger, Marcus, PhD ; Kowanetz, Marcin, PhD ; He, Pei, PhD ; Chen, Daniel S, MD ; Sandler, Alan, MD ; Gandara, David R, Dr
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2017-01, Vol.389 (10066), p.255-265
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MOSBY enables multi-omic inference and spatial biomarker discovery from whole slide images
Author / Creator:Şenbabaoğlu, Yasin ; Prabhakar, Vignesh ; Khormali, Aminollah ; Eastham, Jeff ; Liu, Evan ; Warner, Elisa ; Nabet, Barzin ; Srivastava, Minu ; Ballinger, Marcus ; Liu, Kai
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-08, Vol.14 (1), p.18271-16, Article 18271
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Evaluation of atezolizumab immunogenicity: Clinical pharmacology (part 1)
Author / Creator:Wu, Benjamin ; Sternheim, Nitzan ; Agarwal, Priya ; Suchomel, Julia ; Vadhavkar, Shweta ; Bruno, Rene ; Ballinger, Marcus ; Bernaards, Coen A. ; Chan, Phyllis ; Ruppel, Jane ; Jin, Jin ; Girish, Sandhya ; Joshi, Amita ; Quarmby, Valerie
Publisher:United States: John Wiley & Sons, Inc
Journal title:Clinical and translational science, 2022-01, Vol.15 (1), p.130-140
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C-reactive protein reduction post treatment is associated with improved survival in atezolizumab (anti-PD-L1) treated non-small cell lung cancer patients
Author / Creator:Patil, Namrata S ; Zou, Wei ; Mocci, Simonetta ; Sandler, Alan ; Ballinger, Marcus ; Flynn, Susan ; Kowanetz, Marcin ; Hegde, Priti S
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-02, Vol.16 (2), p.e0246486-e0246486
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Late-differentiated effector neoantigen-specific CD8+ T cells are enriched in peripheral blood of non-small cell lung carcinoma patients responding to atezolizumab treatment
Author / Creator:Fehlings, Michael ; Jhunjhunwala, Suchit ; Kowanetz, Marcin ; O’Gorman, William E. ; Hegde, Priti S. ; Sumatoh, Hermi ; Lee, Boon Heng ; Nardin, Alessandra ; Becht, Etienne ; Flynn, Susan ; Ballinger, Marcus ; Newell, Evan W. ; Yadav, Mahesh
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2019-09, Vol.7 (1), p.249-249, Article 249
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Evaluation of atezolizumab immunogenicity: Efficacy and safety (Part 2)
Author / Creator:Peters, Solange ; Galle, Peter R. ; Bernaards, Coen A. ; Ballinger, Marcus ; Bruno, René ; Quarmby, Valerie ; Ruppel, Jane ; Vilimovskij, Alexandr ; Wu, Benjamin ; Sternheim, Nitzan ; Reck, Martin
Publisher:United States: John Wiley & Sons, Inc
Journal title:Clinical and translational science, 2022-01, Vol.15 (1), p.141-157
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Prediction of overall survival in patients across solid tumors following atezolizumab treatments: A tumor growth inhibition–overall survival modeling framework
Author / Creator:Chan, Phyllis ; Marchand, Mathilde ; Yoshida, Kenta ; Vadhavkar, Shweta ; Wang, Nina ; Lin, Alyse ; Wu, Benjamin ; Ballinger, Marcus ; Sternheim, Nitzan ; Jin, Jin Y. ; Bruno, René
Publisher:United States: John Wiley & Sons, Inc
Journal title:CPT: pharmacometrics and systems pharmacology, 2021-10, Vol.10 (10), p.1171-1182
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Fast progression in non–small cell lung cancer: results from the randomized phase III OAK study evaluating second-line atezolizumab versus docetaxel
Author / Creator:Gandara, David ; Reck, Martin ; Moro-Sibilot, Denis ; Mazieres, Julien ; Gadgeel, Shirish ; Morris, Stefanie ; Cardona, Andres ; Mendus, Diana ; Ballinger, Marcus ; Rittmeyer, Achim ; Peters, Solange
Publisher:England: BMJ Publishing Group LTD
Journal title:Journal for immunotherapy of cancer, 2021-03, Vol.9 (3), p.e001882
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Comparison of SP263 and 22C3 immunohistochemistry PD-L1 assays for clinical efficacy of adjuvant atezolizumab in non-small cell lung cancer: results from the randomized phase III IMpower010 trial
Author / Creator:Zhou, Caicun ; Srivastava, Minu K ; Xu, Hao ; Felip, Enriqueta ; Wakelee, Heather ; Altorki, Nasser ; Reck, Martin ; Liersch, Rüdiger ; Kryzhanivska, Anna ; Oizumi, Satoshi ; Tanaka, Hiroshi ; Hamm, John ; McCune, Steven L ; Bennett, Elizabeth ; Gitlitz, Barbara ; McNally, Virginia ; Ballinger, Marcus ; McCleland, Mark ; Zou, Wei ; Das Thakur, Meghna ; Novello, Silvia
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2023-10, Vol.11 (10), p.e007047
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601 Identification of non-squamous NSCLC molecular subtypes and association with outcomes in the phase 3 IMpower150 study of 1L atezolizumab ± bevacizumab + carboplatin-paclitaxel in metastatic NSCLC
Author / Creator:Lu, Tianshi ; Socinski, Mark A ; Reck, Martin ; West, Howard ; Cappuzzo, Federico ; Barlesi, Fabrice ; Jotte, Robert M ; Müller, Sören ; Hamidi, Habib ; Amitai, Assaf ; Koeppen, Hartmut ; Shames, David S ; Ballinger, Marcus ; Qamra, Aditi ; Srivastava, Minu K ; Nabet, Barzin
Publisher:London: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A684-A684
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606 IMpower110: Tertiary lymphoid structures (TLS) and clinical outcomes in advanced non-small cell lung cancer (NSCLC) treated with first-line atezolizumab or chemotherapy
Author / Creator:Srivastava, Minu K ; Gayevskiy, Velimir ; Ma, Vy ; Estay, Ivette ; Rodas, Miguel Lopez de ; Rajendran, Barani Kumar ; Hoang, Tien ; Ballinger, Marcus ; Amin, Reena ; Herbst, Roy S ; Marinis, Filippo de ; Giaccone, Giuseppe ; Jassem, Jacek ; Spigel, David R ; Schalper, Kurt ; Koeppen, Hartmut ; Shames, David S ; Johnston, Robert ; Giltnane, Jennifer M ; Nabet, Barzin Y
Publisher:London: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A690-A690
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Blood-based tumor mutational burden as a predictor of clinical benefit in non-small-cell lung cancer patients treated with atezolizumab
Author / Creator:Gandara, David R. ; Paul, Sarah M. ; Kowanetz, Marcin ; Schleifman, Erica ; Zou, Wei ; Li, Yan ; Rittmeyer, Achim ; Fehrenbacher, Louis ; Otto, Geoff ; Malboeuf, Christine ; Lieber, Daniel S. ; Lipson, Doron ; Silterra, Jacob ; Amler, Lukas ; Riehl, Todd ; Cummings, Craig A. ; Hegde, Priti S. ; Sandler, Alan ; Ballinger, Marcus ; Fabrizio, David ; Mok, Tony ; Shames, David S.
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2018-09, Vol.24 (9), p.1441-1448
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Peripheral T cell expansion predicts tumour infiltration and clinical response
Author / Creator:Wu, Thomas D. ; Madireddi, Shravan ; de Almeida, Patricia E. ; Banchereau, Romain ; Chen, Ying-Jiun J. ; Chitre, Avantika S. ; Chiang, Eugene Y. ; Iftikhar, Hina ; O’Gorman, William E. ; Au-Yeung, Amelia ; Takahashi, Chikara ; Goldstein, Leonard D. ; Poon, Chungkee ; Keerthivasan, Shilpa ; de Almeida Nagata, Denise E. ; Du, Xiangnan ; Lee, Hyang-Mi ; Banta, Karl L. ; Mariathasan, Sanjeev ; Das Thakur, Meghna ; Huseni, Mahrukh A. ; Ballinger, Marcus ; Estay, Ivette ; Caplazi, Patrick ; Modrusan, Zora ; Delamarre, Lélia ; Mellman, Ira ; Bourgon, Richard ; Grogan, Jane L.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-03, Vol.579 (7798), p.274-278
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Atezolizumab plus cobimetinib and vemurafenib in BRAF-mutated melanoma patients
Author / Creator:Sullivan, Ryan J. ; Hamid, Omid ; Gonzalez, Rene ; Infante, Jeffrey R. ; Patel, Manish R. ; Hodi, F. Stephen ; Lewis, Karl D. ; Tawbi, Hussein A. ; Hernandez, Genevive ; Wongchenko, Matthew J. ; Chang, YiMeng ; Roberts, Louise ; Ballinger, Marcus ; Yan, Yibing ; Cha, Edward ; Hwu, Patrick
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2019-06, Vol.25 (6), p.929-935
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Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti–PD-L1)
Author / Creator:Kowanetz, Marcin ; Zou, Wei ; Gettinger, Scott N. ; Koeppen, Hartmut ; Kockx, Mark ; Schmid, Peter ; Kadel, Edward E. ; Wistuba, Ignacio ; Chaft, Jamie ; Rizvi, Naiyer A. ; Spigel, David R. ; Spira, Alexander ; Hirsch, Fred R. ; Cohen, Victor ; Smith, Dustin ; Boyd, Zach ; Miley, Natasha ; Flynn, Susan ; Leveque, Vincent ; Shames, David S. ; Ballinger, Marcus ; Mocci, Simonetta ; Shankar, Geetha ; Funke, Roel ; Hampton, Garret ; Sandler, Alan ; Amler, Lukas ; Mellman, Ira ; Chen, Daniel S. ; Hegde, Priti S.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-10, Vol.115 (43), p.E10119-E10126
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ArticlesPeer ReviewedFull Text
Tumor Growth Inhibition-Overall Survival Subgroup Analysis of Atezolizumab in the IMpower150 Study
Author / Creator:Yoshida, Kenta ; Chan, Phyllis ; Marchand, Mathilde ; Zhang, Rong ; Wu, Benjamin ; Ballinger, Marcus ; Sternheim, Nitzan
Publisher:Springer
Journal title:The AAPS journal, 2022-05, Vol.24 (3)
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C-reactive protein reduction post treatment is associated with improved survival in atezolizumab
Author / Creator:Patil, Namrata S ; Zou, Wei ; Mocci, Simonetta ; Sandler, Alan ; Ballinger, Marcus ; Flynn, Susan ; Kowanetz, Marcin ; Hegde, Priti S
Publisher:Public Library of Science
Journal title:PloS one, 2021-02, Vol.16 (2), p.e0246486
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Time-dependent population PK models of single-agent atezolizumab in patients with cancer
Author / Creator:Marchand, Mathilde ; Zhang, Rong ; Chan, Phyllis ; Quarmby, Valerie ; Ballinger, Marcus ; Sternheim, Nitzan ; Wu, Benjamin ; Jin, Jin Y. ; Bruno, René
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer chemotherapy and pharmacology, 2021-08, Vol.88 (2), p.211-221
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Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): a multicentre, open-label, phase 2 randomised controlled trial

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iRECIST: guidelines for response criteria for use in trials testing immunotherapeutics

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Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): a phase 3, open-label, multicentre randomised controlled trial

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MOSBY enables multi-omic inference and spatial biomarker discovery from whole slide images

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Evaluation of atezolizumab immunogenicity: Clinical pharmacology (part 1)

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C-reactive protein reduction post treatment is associated with improved survival in atezolizumab (anti-PD-L1) treated non-small cell lung cancer patients

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Late-differentiated effector neoantigen-specific CD8+ T cells are enriched in peripheral blood of non-small cell lung carcinoma patients responding to atezolizumab treatment

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Evaluation of atezolizumab immunogenicity: Efficacy and safety (Part 2)

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Prediction of overall survival in patients across solid tumors following atezolizumab treatments: A tumor growth inhibition–overall survival modeling framework

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Fast progression in non–small cell lung cancer: results from the randomized phase III OAK study evaluating second-line atezolizumab versus docetaxel

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Comparison of SP263 and 22C3 immunohistochemistry PD-L1 assays for clinical efficacy of adjuvant atezolizumab in non-small cell lung cancer: results from the randomized phase III IMpower010 trial

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601 Identification of non-squamous NSCLC molecular subtypes and association with outcomes in the phase 3 IMpower150 study of 1L atezolizumab ± bevacizumab + carboplatin-paclitaxel in metastatic NSCLC

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606 IMpower110: Tertiary lymphoid structures (TLS) and clinical outcomes in advanced non-small cell lung cancer (NSCLC) treated with first-line atezolizumab or chemotherapy

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Blood-based tumor mutational burden as a predictor of clinical benefit in non-small-cell lung cancer patients treated with atezolizumab

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Peripheral T cell expansion predicts tumour infiltration and clinical response

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Atezolizumab plus cobimetinib and vemurafenib in BRAF-mutated melanoma patients

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Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti–PD-L1)

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Tumor Growth Inhibition-Overall Survival Subgroup Analysis of Atezolizumab in the IMpower150 Study

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C-reactive protein reduction post treatment is associated with improved survival in atezolizumab

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Time-dependent population PK models of single-agent atezolizumab in patients with cancer

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