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Single-Cell Profiling Reveals Immune-Based Mechanisms Underlying Tumor Radiosensitization by a Novel Mn Porphyrin Clinical Candidate, MnTnBuOE-2-PyP5+ (BMX-001)
Author / Creator:Noh, Sun Up ; Lim, Jinyeong ; Shin, Sung-Won ; Kim, Yeeun ; Park, Woong-Yang ; Batinic-Haberle, Ines ; Choi, Changhoon ; Park, Won
Publisher:Basel: MDPI AG
Journal title:Antioxidants, 2024-04, Vol.13 (4), p.477
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Superoxide Dismutase Mimics: Chemistry, Pharmacology, and Therapeutic Potential
Author / Creator:Batinic-Haberle, Ines ; Reboucas, Julio S ; Spasojevic, Ivan
Publisher:United States: Mary Ann Liebert, Inc
Journal title:Antioxidants & redox signaling, 2010-09, Vol.13 (6), p.877-918
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Antibacterial Activity of Synthetic Cationic Iron Porphyrins
Author / Creator:Tovmasyan, Artak ; Batinic-Haberle, Ines ; Benov, Ludmil
Publisher:Basel: MDPI AG
Journal title:Antioxidants, 2020-10, Vol.9 (10), p.972
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NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment
Author / Creator:Moon, Eui Jung ; Sonveaux, Pierre ; Porporato, Paolo E. ; Danhier, Pierre ; Gallez, Bernard ; Batinic-Haberle, Ines ; Nien, Yu-Chih ; Schroeder, Thies ; Dewhirst, Mark W. ; Semenza, Gregg L.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-11, Vol.107 (47), p.20477-20482
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Post-illumination cellular effects of photodynamic treatment
Author / Creator:Charara, Malak ; Tovmasyan, Artak ; Batinic-Haberle, Ines ; Craik, James ; Benov, Ludmil
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-12, Vol.12 (12), p.e0188535
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Whole thorax irradiation of non-human primates induces persistent nuclear damage and gene expression changes in peripheral blood cells
Author / Creator:Ghandhi, Shanaz A. ; Turner, Helen C. ; Shuryak, Igor ; Dugan, Gregory O. ; Bourland, J. Daniel ; Olson, John D. ; Tooze, Janet A. ; Morton, Shad R. ; Batinic-Haberle, Ines ; Cline, J. Mark ; Amundson, Sally A.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2018-01, Vol.13 (1), p.e0191402-e0191402
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2-Hydroxyglutarate Production, but Not Dominant Negative Function, Is Conferred by Glioma-Derived NADP+-Dependent Isocitrate Dehydrogenase Mutations
Author / Creator:Jin, Genglin ; Reitman, Zachary J. ; Spasojevic, Ivan ; Batinic-Haberle, Ines ; Yang, Jian ; Schmidt-Kittler, Oleg ; Bigner, Darell D. ; Yan, Hai
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-02, Vol.6 (2), p.e16812-e16812
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Targeting Mitochondria by Zn(II)N-Alkylpyridylporphyrins: The Impact of Compound Sub-Mitochondrial Partition on Cell Respiration and Overall Photodynamic Efficacy
Author / Creator:Odeh, Ahmad M. ; Craik, James D. ; Ezzeddine, Rima ; Tovmasyan, Artak ; Batinic-Haberle, Ines ; Benov, Ludmil T.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-09, Vol.9 (9), p.e108238
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Effects of Manganese Porphyrins on Cellular Sulfur Metabolism
Author / Creator:Olson, Kenneth R. ; Gao, Yan ; Steiger, Andrea K. ; Pluth, Michael D. ; Tessier, Charles R. ; Markel, Troy A. ; Boone, David ; Stahelin, Robert V. ; Batinic-Haberle, Ines ; Straubg, Karl D.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2020-02, Vol.25 (4), p.980
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Manganese Porphyrin Promotes Post Cardiac Arrest Recovery in Mice and Rats
Author / Creator:Wang, Peng ; Li, Ying ; Yan, Baihui ; Yang, Zhong ; Li, Litao ; Cao, Zhipeng ; Li, Xuan ; Batinic-Haberle, Ines ; Spasojevic, Ivan ; Warner, David ; Sheng, Huaxin
Publisher:Switzerland: MDPI AG
Journal title:Biology (Basel, Switzerland), 2022-06, Vol.11 (7), p.957
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MnTnHex-2-PyP5+, Coupled to Radiation, Suppresses Metastasis of 4T1 and MDA-MB-231 Breast Cancer via AKT/Snail/EMT Pathways
Author / Creator:Shin, Sung-Won ; Choi, Changhoon ; Kim, Hakyoung ; Kim, Yeeun ; Park, Sohee ; Kim, Shin-Yeong ; Batinic-Haberle, Ines ; Park, Won
Publisher:Basel: MDPI AG
Journal title:Antioxidants, 2021-11, Vol.10 (11), p.1769
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Manganese Porphyrin-Based SOD Mimetics Produce Polysulfides from Hydrogen Sulfide
Author / Creator:Olson, Kenneth R. ; Gao, Yan ; Arif, Faihaan ; Patel, Shivali ; Yuan, Xiaotong ; Mannam, Varun ; Howard, Scott ; Batinic-Haberle, Ines ; Fukuto, Jon ; Minnion, Magdalena ; Feelisch, Martin ; Straub, Karl D.
Publisher:Switzerland: MDPI AG
Journal title:Antioxidants, 2019-12, Vol.8 (12), p.639
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Intracarotid Infusion of Redox-Active Manganese Porphyrin, MnTnBuOE-2-PyP5+, following Reperfusion Improves Long-Term, 28-Day Post-Stroke Outcomes in Rats
Author / Creator:Li, Xuan ; Duan, Weina ; Du, Li ; Chu, Dongmei ; Wang, Peng ; Yang, Zhong ; Qu, Xingguang ; Yang, Zhenxing ; Batinic-Haberle, Ines ; Spasojevic, Ivan ; Warner, David S. ; Crapo, James D. ; Treggiari, Miriam M. ; Sheng, Huaxin
Publisher:Basel: MDPI AG
Journal title:Antioxidants, 2023-10, Vol.12 (10), p.1861
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MnTnHex-2-PyP5+ Displays Anticancer Properties and Enhances Cisplatin Effects in Non-Small Cell Lung Cancer Cells
Author / Creator:Soares, Rita ; Manguinhas, Rita ; Costa, João ; Saraiva, Nuno ; Gil, Nuno ; Rosell, Rafael ; Camões, Sérgio ; Batinic-Haberle, Ines ; Spasojevic, Ivan ; Castro, Matilde ; Miranda, Joana ; Amaro, Filipa ; Pinto, Joana ; Fernandes, Ana ; Guedes de Pinho, Paula ; Oliveira, Nuno
Publisher:Basel: MDPI AG
Journal title:Antioxidants, 2022-11, Vol.11 (11), p.2198
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The SOD Mimic MnTnHex-2-PyP5+ Reduces the Viability and Migration of 786-O Human Renal Cancer Cells
Author / Creator:Costa, João G. ; Saraiva, Nuno ; Batinic-Haberle, Ines ; Castro, Matilde ; Oliveira, Nuno G. ; Fernandes, Ana S.
Publisher:Basel: MDPI AG
Journal title:Antioxidants, 2019-10, Vol.8 (10), p.490
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Fe Porphyrin-Based SOD Mimic and Redox-Active Compound, (OH)FeTnHex-2-PyP4+, in a Rodent Ischemic Stroke (MCAO) Model: Efficacy and Pharmacokinetics as Compared to Its Mn Analogue, (H2O)MnTnHex-2-PyP5
Author / Creator:Li, Litao ; Tovmasyan, Artak ; Sheng, Huaxin ; Xu, Bin ; Sampaio, Romulo S. ; Reboucas, Julio S. ; Warner, David S. ; Batinic-Haberle, Ines ; Spasojevic, Ivan
Publisher:MDPI
Journal title:Antioxidants, 2020-06, Vol.9 (6), p.467
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Post-Irradiation Treatment with a Superoxide Dismutase Mimic, MnTnHex-2-PyP5+, Mitigates Radiation Injury in the Lungs of Non-Human Primates after Whole-Thorax Exposure to Ionizing Radiation
Author / Creator:Cline, John ; Dugan, Greg ; Bourland, John ; Perry, Donna ; Stitzel, Joel ; Weaver, Ashley ; Jiang, Chen ; Tovmasyan, Artak ; Owzar, Kouros ; Spasojevic, Ivan ; Batinic-Haberle, Ines ; Vujaskovic, Zeljko
Publisher:Basel: MDPI AG
Journal title:Antioxidants, 2018-03, Vol.7 (3), p.40
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Oxygen Radical Inhibition of Nitric Oxide-Dependent Vascular Function in Sickle Cell Disease
Author / Creator:Aslan, Mutay ; Ryan, Thomas M. ; Adler, Brian ; Townes, Tim M. ; Parks, Dale A. ; Thompson, J. Anthony ; Tousson, Albert ; Gladwin, Mark T. ; Patel, Rakesh P. ; Tarpey, Margaret M. ; Batinic-Haberle, Ines ; White, C. Roger ; Freeman, Bruce A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2001-12, Vol.98 (26), p.15215-15220
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Update on hypoxia-inducible factors and hydroxylases in oxygen regulatory pathways: from physiology to therapeutics
Author / Creator:Ratcliffe, Peter ; Koivunen, Peppi ; Myllyharju, Johanna ; Ragoussis, Jiannis ; Bovée, Judith ; Batinic-Haberle, Ines ; Vinatier, Claire ; Trichet, Valérie ; Robriquet, Florence ; Oliver, Lisa ; Gardie, Betty
Publisher:New Zealand: Taylor & Francis Ltd
Journal title:Hypoxia, 2017-01, Vol.5, p.11-20
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A Metalloporphyrin-Based Superoxide Dismutase Mimic Inhibits Adoptive Transfer of Autoimmune Diabetes by a Diabetogenic T-Cell Clone
Author / Creator:Piganelli, Jon D. ; Flores, Sonia C. ; Cruz, Coral ; Koepp, Jeffrey ; Batinic-Haberle, Ines ; Crapo, James ; Day, Brian ; Kachadourian, Remy ; Young, Rebekah ; Bradley, Brenda ; Haskins, Kathryn
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2002-02, Vol.51 (2), p.347-355
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Showing 1 to 20 of 62 results

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Single-Cell Profiling Reveals Immune-Based Mechanisms Underlying Tumor Radiosensitization by a Novel Mn Porphyrin Clinical Candidate, MnTnBuOE-2-PyP5+ (BMX-001)

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Superoxide Dismutase Mimics: Chemistry, Pharmacology, and Therapeutic Potential

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Antibacterial Activity of Synthetic Cationic Iron Porphyrins

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NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment

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Post-illumination cellular effects of photodynamic treatment

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Whole thorax irradiation of non-human primates induces persistent nuclear damage and gene expression changes in peripheral blood cells

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2-Hydroxyglutarate Production, but Not Dominant Negative Function, Is Conferred by Glioma-Derived NADP+-Dependent Isocitrate Dehydrogenase Mutations

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Targeting Mitochondria by Zn(II)N-Alkylpyridylporphyrins: The Impact of Compound Sub-Mitochondrial Partition on Cell Respiration and Overall Photodynamic Efficacy

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Effects of Manganese Porphyrins on Cellular Sulfur Metabolism

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Manganese Porphyrin Promotes Post Cardiac Arrest Recovery in Mice and Rats

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MnTnHex-2-PyP5+, Coupled to Radiation, Suppresses Metastasis of 4T1 and MDA-MB-231 Breast Cancer via AKT/Snail/EMT Pathways

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Manganese Porphyrin-Based SOD Mimetics Produce Polysulfides from Hydrogen Sulfide

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Intracarotid Infusion of Redox-Active Manganese Porphyrin, MnTnBuOE-2-PyP5+, following Reperfusion Improves Long-Term, 28-Day Post-Stroke Outcomes in Rats

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MnTnHex-2-PyP5+ Displays Anticancer Properties and Enhances Cisplatin Effects in Non-Small Cell Lung Cancer Cells

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The SOD Mimic MnTnHex-2-PyP5+ Reduces the Viability and Migration of 786-O Human Renal Cancer Cells

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Fe Porphyrin-Based SOD Mimic and Redox-Active Compound, (OH)FeTnHex-2-PyP4+, in a Rodent Ischemic Stroke (MCAO) Model: Efficacy and Pharmacokinetics as Compared to Its Mn Analogue, (H2O)MnTnHex-2-PyP5

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Post-Irradiation Treatment with a Superoxide Dismutase Mimic, MnTnHex-2-PyP5+, Mitigates Radiation Injury in the Lungs of Non-Human Primates after Whole-Thorax Exposure to Ionizing Radiation

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Oxygen Radical Inhibition of Nitric Oxide-Dependent Vascular Function in Sickle Cell Disease

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Update on hypoxia-inducible factors and hydroxylases in oxygen regulatory pathways: from physiology to therapeutics

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A Metalloporphyrin-Based Superoxide Dismutase Mimic Inhibits Adoptive Transfer of Autoimmune Diabetes by a Diabetogenic T-Cell Clone

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