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ArticlesPeer ReviewedFull Text
TMEM164 is an acyltransferase that forms ferroptotic C20:4 ether phospholipids
Author / Creator:Reed, Alex ; Ware, Timothy ; Li, Haoxin ; Fernando Bazan, J. ; Cravatt, Benjamin F.
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2023-03, Vol.19 (3), p.378-388
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Reanalysis of cryo-EM data reveals ALK-cytokine assemblies with both 2:1 and 2:2 stoichiometries
Author / Creator:Felix, Jan ; De Munck, Steven ; Bazan, J. Fernando ; Savvides, Savvas N.
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2025-04, Vol.23 (4), p.e3003124
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Structural basis of cytokine-mediated activation of ALK family receptors
Author / Creator:De Munck, Steven ; Provost, Mathias ; Kurikawa, Michiko ; Omori, Ikuko ; Mukohyama, Junko ; Felix, Jan ; Bloch, Yehudi ; Abdel-Wahab, Omar ; Bazan, J. Fernando ; Yoshimi, Akihide ; Savvides, Savvas N.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-12, Vol.600 (7887), p.143-147
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Structure of the activating IL-1 receptor signaling complex
Author / Creator:Thomas, Christoph ; Bazan, J Fernando ; Garcia, K Christopher
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2012-04, Vol.19 (4), p.455-457
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Tonic ubiquitination of the central body weight regulator melanocortin receptor 4 (MC4R) promotes its constitutive exit from cilia
Author / Creator:Ojeda-Naharros, Irene ; Das, Tirthasree ; Castro, Ralph A. ; Bazan, J. Fernando ; Vaisse, Christian ; Nachury, Maxence V.
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2025-02, Vol.23 (2), p.e3003025
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Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell–cell adhesion and signaling mechanism that requires cis-trans receptor clustering
Author / Creator:Stengel, Katharina F ; Harden-Bowles, Kristin ; Yu, Xin ; Rouge, Lionel ; Yin, Jianping ; Comps-Agrar, Laëtitia ; Wiesmann, Christian ; Bazan, J. Fernando ; Eaton, Dan L ; Grogan, Jane L
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (14), p.5399-5404
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Role for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/Akt
Author / Creator:Troutman, Ty Dale ; Hu, Wei ; Fulenchek, Stephanie ; Yamazaki, Tetsuo ; Kurosaki, Tomohiro ; Bazan, J. Fernando ; Pasare, Chandrashekhar
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-01, Vol.109 (1), p.273-278
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DUBA: A Deubiquitinase That Regulates Type I Interferon Production
Author / Creator:Kayagaki, Nobuhiko ; Phung, Qui ; Chan, Salina ; Chaudhari, Ruchir ; Quan, Casey ; O'Rourke, Karen M ; Eby, Michael ; Pietras, Eric ; Cheng, Genhong ; Bazan, J. Fernando ; Zhang, Zemin ; Arnott, David ; Dixit, Vishva M
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2007-12, Vol.318 (5856), p.1628-1632
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Honey bee Royalactin unlocks conserved pluripotency pathway in mammals
Author / Creator:Wan, Derrick C ; Morgan, Stefanie L ; Spencley, Andrew L ; Mariano, Natasha ; Chang, Erin Y ; Shankar, Gautam ; Luo, Yunhai ; Li, Ted H ; Huh, Dana ; Huynh, Star K ; Garcia, Jasmine M ; Dovey, Cole M ; Lumb, Jennifer ; Liu, Ling ; Brown, Katharine V ; Bermudez, Abel ; Luong, Richard ; Zeng, Hong ; Mascetti, Victoria L ; Pitteri, Sharon J ; Wang, Jordon ; Tu, Hua ; Quarta, Marco ; Sebastiano, Vittorio ; Nusse, Roel ; Rando, Thomas A ; Carette, Jan E ; Bazan, J Fernando ; Wang, Kevin C
Publisher:London: Nature Publishing Group
Journal title:Nature communications, 2018-12, Vol.9, p.1-9
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The transmembrane domain of Frey1 harbors a transplantable inhibitory motif for intramembrane proteases
Publisher:Basel: Springer Nature B.V
Journal title:Cellular and molecular life sciences : CMLS, 2023-06, Vol.80 (6), p.170
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A Family of Human Receptors Structurally Related to Drosophila Toll
Author / Creator:Rock, Fernando L. ; Hardiman, Gary ; Timans, Jackie C. ; Kastelein, Robert A. ; Bazan, J. Fernando
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1998-01, Vol.95 (2), p.588-593
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ArticlesPeer ReviewedFull Text
Mechanism of receptor assembly via the pleiotropic adipokine Leptin
Author / Creator:Tsirigotaki, Alexandra ; Dansercoer, Ann ; Verschueren, Koen H. G. ; Marković, Iva ; Pollmann, Christoph ; Hafer, Maximillian ; Felix, Jan ; Birck, Catherine ; Van Putte, Wouter ; Catteeuw, Dominiek ; Tavernier, Jan ; Fernando Bazan, J. ; Piehler, Jacob ; Savvides, Savvas N. ; Verstraete, Kenneth
Publisher:New York: Nature Publishing Group US
Journal title:Nature (London), 2023-04, Vol.30 (4), p.551-563
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ArticlesPeer ReviewedFull Text
Smoothened Mutation Confers Resistance to a Hedgehog Pathway Inhibitor in Medulloblastoma
Author / Creator:Yauch, Robert L. ; Dijkgraaf, Gerrit J. P. ; Alicke, Bruno ; Januario, Thomas ; Ahn, Christina P. ; Holcomb, Thomas ; Pujara, Kanan ; Stinson, Jeremy ; Callahan, Christopher A. ; Tang, Tracy ; Bazan, J. Fernando ; Kan, Zhengyan ; Seshagiri, Somasekar ; Hann, Christine L. ; Gould, Stephen E. ; Low, Jennifer A. ; Rudin, Charles M. ; de Sauvage, Frederic J.
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2009-10, Vol.326 (5952), p.572-574
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A newly defined interleukin-1?
Author / Creator:Bazan, J. Fernando ; Timans, Jackie C. ; Kastelein, Robert A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 1996-02, Vol.379 (6566), p.591-591
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Formation and Hydrolysis of Cyclic ADP-Ribose Catalyzed by Lymphocyte Antigen CD38
Author / Creator:Howard, Maureen ; Grimaldi, J. Christopher ; Bazan, J. Fernando ; Lund, Frances E. ; Santos-Argumedo, Leopoldo ; Parkhouse, R. M. E. ; Walseth, Timothy F. ; Lee, Hon Cheung
Publisher:Washington, DC: American Society for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 1993-11, Vol.262 (5136), p.1056-1059
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Identification of a Novel selD Homolog from Eukaryotes, Bacteria, and Archaea: Is there an Autoregulatory Mechanism in Selenocysteine Metabolism?
Author / Creator:Guimaraes, M. Jorge ; Peterson, David ; Vicari, Alain ; Cocks, Benjamin G. ; Copeland, Neal G. ; Gilbert, Debra J. ; Jenkins, Nancy A. ; Ferrick, David A. ; Kastelein, Robert A. ; Bazan, J. Fernando ; Zlotnik, Albert
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1996-12, Vol.93 (26), p.15086-15091
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ArticlesPeer ReviewedFull Text
Designs on a curve
Author / Creator:Bazan, J Fernando ; Kajava, Andrey V
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2015-02, Vol.22 (2), p.103-105
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The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling
Author / Creator:Bosanac, Ivan ; Maun, Henry R ; Scales, Suzie J ; Wen, Xiaohui ; Lingel, Andreas ; Bazan, J Fernando ; de Sauvage, Frederic J ; Hymowitz, Sarah G ; Lazarus, Robert A
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2009-07, Vol.16 (7), p.691-697
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Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding
Author / Creator:Appleton, Brent A ; Wu, Ping ; Maloney, Janice ; Yin, JianPing ; Liang, Wei-Ching ; Stawicki, Scott ; Mortara, Kyle ; Bowman, Krista K ; Elliott, J Michael ; Desmarais, William ; Bazan, J Fernando ; Bagri, Anil ; Tessier-Lavigne, Marc ; Koch, Alexander W ; Wu, Yan ; Watts, Ryan J ; Wiesmann, Christian
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2007-11, Vol.26 (23), p.4902-4912
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Structure of Melanoma Inhibitory Activity Protein, a Member of a Recently Identified Family of Secreted Proteins
Author / Creator:Lougheed, Julie C. ; Holton, James M. ; Alber, Tom ; Bazan, J. Fernando ; Handel, Tracy M.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2001-05, Vol.98 (10), p.5515-5520
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Showing 1 to 20 of 49 results

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TMEM164 is an acyltransferase that forms ferroptotic C20:4 ether phospholipids

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Reanalysis of cryo-EM data reveals ALK-cytokine assemblies with both 2:1 and 2:2 stoichiometries

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Structural basis of cytokine-mediated activation of ALK family receptors

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Structure of the activating IL-1 receptor signaling complex

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Tonic ubiquitination of the central body weight regulator melanocortin receptor 4 (MC4R) promotes its constitutive exit from cilia

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Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell–cell adhesion and signaling mechanism that requires cis-trans receptor clustering

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Role for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/Akt

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DUBA: A Deubiquitinase That Regulates Type I Interferon Production

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Honey bee Royalactin unlocks conserved pluripotency pathway in mammals

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The transmembrane domain of Frey1 harbors a transplantable inhibitory motif for intramembrane proteases

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A Family of Human Receptors Structurally Related to Drosophila Toll

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Mechanism of receptor assembly via the pleiotropic adipokine Leptin

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Smoothened Mutation Confers Resistance to a Hedgehog Pathway Inhibitor in Medulloblastoma

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A newly defined interleukin-1?

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Formation and Hydrolysis of Cyclic ADP-Ribose Catalyzed by Lymphocyte Antigen CD38

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Identification of a Novel selD Homolog from Eukaryotes, Bacteria, and Archaea: Is there an Autoregulatory Mechanism in Selenocysteine Metabolism?

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Designs on a curve

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The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling

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Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding

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Structure of Melanoma Inhibitory Activity Protein, a Member of a Recently Identified Family of Secreted Proteins

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