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ArticlesPeer ReviewedFull Text
GAD65 tunes the functions of Best1 as a GABA receptor and a neurotransmitter conducting channel
Author / Creator:Wang, Jiali ; Owji, Aaron P. ; Kittredge, Alec ; Clark, Zada ; Zhang, Yu ; Yang, Tingting
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-09, Vol.15 (1), p.8051-11, Article 8051
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ArticlesPeer ReviewedFull Text
Control of motor coordination by astrocytic tonic GABA release through modulation of excitation/inhibition balance in cerebellum
Author / Creator:Woo, Junsung ; Min, Joo Ok ; Kang, Dae-Si ; Kim, Yoo Sung ; Jung, Guk Hwa ; Park, Hyun Jung ; Kim, Sunpil ; An, Heeyoung ; Kwon, Jea ; Kim, Jeongyeon ; Shim, Insop ; Kim, Hyung-Gun ; Lee, C. Justin ; Yoon, Bo-Eun
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-05, Vol.115 (19), p.5004-5009
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ArticlesPeer ReviewedFull Text
Mutation spectrum of the bestrophin-1 gene in a large Chinese cohort with bestrophinopathy
Author / Creator:Gao, Feng-Juan ; Qi, Yu-He ; Hu, Fang-Yuan ; Wang, Dan-Dan ; Xu, Ping ; Guo, Jing-Li ; Li, Jian-Kang ; Zhang, Yong-Jin ; Li, Wei ; Chen, Fang ; Xu, Ge-Zhi ; Liu, Wei ; Chang, Qing ; Wu, Ji-Hong
Publisher:England: BMJ Publishing Group LTD
Journal title:British journal of ophthalmology, 2020-06, Vol.104 (6), p.846-851
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ArticlesPeer ReviewedFull Text
Neurotransmitter-bound bestrophin channel structures reveal small molecule drug targeting sites for disease treatment
Author / Creator:Owji, Aaron P. ; Dong, Jingyun ; Kittredge, Alec ; Wang, Jiali ; Zhang, Yu ; Yang, Tingting
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-12, Vol.15 (1), p.10766-10, Article 10766
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ArticlesPeer ReviewedFull Text
Bestrophin-2 and glutamine synthetase form a complex for glutamate release
Author / Creator:Owji, Aaron P. ; Yu, Kuai ; Kittredge, Alec ; Wang, Jiali ; Zhang, Yu ; Yang, Tingting
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2022-11, Vol.611 (7934), p.180-187
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ArticlesPeer ReviewedFull Text
Cryo-EM structures of thylakoid-located voltage-dependent chloride channel VCCN1
Author / Creator:Hagino, Tatsuya ; Kato, Takafumi ; Kasuya, Go ; Kobayashi, Kan ; Kusakizako, Tsukasa ; Hamamoto, Shin ; Sobajima, Tomoaki ; Fujiwara, Yuichiro ; Yamashita, Keitaro ; Kawasaki, Hisashi ; Maturana, Andrés D. ; Nishizawa, Tomohiro ; Nureki, Osamu
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-05, Vol.13 (1), p.2505-2505, Article 2505
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ArticlesPeer ReviewedFull Text
ATP activates bestrophin ion channels through direct interaction
Author / Creator:Zhang, Yu ; Kittredge, Alec ; Ward, Nancy ; Ji, Changyi ; Chen, Shoudeng ; Yang, Tingting
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-08, Vol.9 (1), p.3126-11, Article 3126
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ArticlesPeer ReviewedFull Text
Tadalafil Rescues the p.M325T Mutant of Best1 Chloride Channel
Author / Creator:Elverson, Kathleen ; Warwicker, Jim ; Freeman, Sally ; Manson, Forbes
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2023-04, Vol.28 (8), p.3317
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ArticlesPeer ReviewedFull Text
Bestrophin-4 relays HES4 and interacts with TWIST1 to suppress epithelial-to-mesenchymal transition in colorectal cancer cells
Author / Creator:Wang, Zijing ; Xia, Bihan ; Qi, Shaochong ; Zhang, Xian ; Zhang, Xiaoshuang ; Li, Yan ; Wang, Huimin ; Zhang, Miao ; Zhao, Ziyi ; Kerr, David ; Yang, Li ; Cai, Shijie ; Yang, Jilin
Publisher:England: eLife Sciences Publications, Ltd
Journal title:eLife, 2024-12, Vol.12
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ArticlesPeer ReviewedFull Text
Mutation-Dependent Pathomechanisms Determine the Phenotype in the Bestrophinopathies
Author / Creator:Nachtigal, Anna-Lena ; Milenkovic, Andrea ; Brandl, Caroline ; Schulz, Heidi L. ; Duerr, Lisa M. J. ; Lang, Gabriele E. ; Reiff, Charlotte ; Herrmann, Philipp ; Kellner, Ulrich ; Weber, Bernhard H.F.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-02, Vol.21 (5), p.1597
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ArticlesPeer ReviewedFull Text
Molecular mechanisms of gating in the calcium-activated chloride channel bestrophin
Author / Creator:Miller, Alexandria N ; Vaisey, George ; Long, Stephen B
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2019-01, Vol.8
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ArticlesPeer ReviewedFull Text
Adult-Onset Vitelliform Macular Dystrophy caused by BEST1 p.Ile38Ser Mutation is a Mild Form of Best Vitelliform Macular Dystrophy
Author / Creator:Jun, Ikhyun ; Lee, Joon Suk ; Lee, Ji Hwan ; Lee, Christopher Seungkyu ; Choi, Seung-il ; Gee, Heon Yung ; Lee, Min Goo ; Kim, Eung Kweon
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-08, Vol.7 (1), p.9146-9146, Article 9146
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ArticlesPeer ReviewedFull Text
Restoration of mutant bestrophin-1 expression, localisation and function in a polarised epithelial cell model
Author / Creator:Uggenti, Carolina ; Briant, Kit ; Streit, Anne-Kathrin ; Thomson, Steven ; Koay, Yee Hui ; Baines, Richard A. ; Swanton, Eileithyia ; Manson, Forbes D.
Publisher:England: The Company of Biologists Ltd
Journal title:Disease models & mechanisms, 2016-11, Vol.9 (11), p.1317-1328
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ArticlesPeer ReviewedFull Text
The Ca 2+ -activated chloride channel anoctamin-2 mediates spike-frequency adaptation and regulates sensory transmission in thalamocortical neurons
Author / Creator:Ha, Go Eun ; Lee, Jaekwang ; Kwak, Hankyul ; Song, Kiyeong ; Kwon, Jea ; Jung, Soon-Young ; Hong, Joohyeon ; Chang, Gyeong-Eon ; Hwang, Eun Mi ; Shin, Hee-Sup ; Lee, C Justin ; Cheong, Eunji
Publisher:England
Journal title:Nature communications, 2016-12, Vol.7, p.13791
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GAD65 tunes the functions of Best1 as a GABA receptor and a neurotransmitter conducting channel

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Control of motor coordination by astrocytic tonic GABA release through modulation of excitation/inhibition balance in cerebellum

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Mutation spectrum of the bestrophin-1 gene in a large Chinese cohort with bestrophinopathy

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Neurotransmitter-bound bestrophin channel structures reveal small molecule drug targeting sites for disease treatment

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Bestrophin-2 and glutamine synthetase form a complex for glutamate release

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Cryo-EM structures of thylakoid-located voltage-dependent chloride channel VCCN1

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ATP activates bestrophin ion channels through direct interaction

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Tadalafil Rescues the p.M325T Mutant of Best1 Chloride Channel

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Bestrophin-4 relays HES4 and interacts with TWIST1 to suppress epithelial-to-mesenchymal transition in colorectal cancer cells

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Mutation-Dependent Pathomechanisms Determine the Phenotype in the Bestrophinopathies

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Molecular mechanisms of gating in the calcium-activated chloride channel bestrophin

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Adult-Onset Vitelliform Macular Dystrophy caused by BEST1 p.Ile38Ser Mutation is a Mild Form of Best Vitelliform Macular Dystrophy

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Restoration of mutant bestrophin-1 expression, localisation and function in a polarised epithelial cell model

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The Ca 2+ -activated chloride channel anoctamin-2 mediates spike-frequency adaptation and regulates sensory transmission in thalamocortical neurons

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