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ArticlesPeer ReviewedFull Text
Quantification of SARS-CoV-2 neutralizing antibody by wild-type plaque reduction neutralization, microneutralization and pseudotyped virus neutralization assays
Author / Creator:Bewley, Kevin R. ; Coombes, Naomi S. ; Gagnon, Luc ; McInroy, Lorna ; Baker, Natalie ; Shaik, Imam ; St-Jean, Julien R. ; St-Amant, Natalie ; Buttigieg, Karen R. ; Humphries, Holly E. ; Godwin, Kerry J. ; Brunt, Emily ; Allen, Lauren ; Leung, Stephanie ; Brown, Phillip J. ; Penn, Elizabeth J. ; Thomas, Kelly ; Kulnis, Greg ; Hallis, Bassam ; Carroll, Miles ; Funnell, Simon ; Charlton, Sue
Publisher:London: Nature Publishing Group UK
Journal title:Nature protocols, 2021-06, Vol.16 (6), p.3114-3140
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Intranasal Infection of Ferrets with SARS-CoV-2 as a Model for Asymptomatic Human Infection
Author / Creator:Everett, Helen E. ; Lean, Fabian Z. X. ; Byrne, Alexander M. P. ; van Diemen, Pauline M. ; Rhodes, Shelley ; James, Joe ; Mollett, Benjamin ; Coward, Vivien J. ; Skinner, Paul ; Warren, Caroline J. ; Bewley, Kevin R. ; Watson, Samantha ; Hurley, Shellene ; Ryan, Kathryn A. ; Hall, Yper ; Simmons, Hugh ; Núñez, Alejandro ; Carroll, Miles W. ; Brown, Ian H. ; Brookes, Sharon M.
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2021-01, Vol.13 (1), p.113
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Development of immunohistochemistry and in situ hybridisation for the detection of SARS-CoV and SARS-CoV-2 in formalin-fixed paraffin-embedded specimens
Author / Creator:Lean, Fabian Z. X. ; Lamers, Mart M. ; Smith, Samuel P. ; Shipley, Rebecca ; Schipper, Debby ; Temperton, Nigel ; Haagmans, Bart L. ; Banyard, Ashley C. ; Bewley, Kevin R. ; Carroll, Miles W. ; Brookes, Sharon M. ; Brown, Ian ; Nuñez, Alejandro
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-12, Vol.10 (1), p.21894-21894, Article 21894
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mRNA vaccination in people over 80 years of age induces strong humoral immune responses against SARS-CoV-2 with cross neutralization of P.1 Brazilian variant
Author / Creator:Parry, Helen ; Tut, Gokhan ; Bruton, Rachel ; Faustini, Sian ; Stephens, Christine ; Saunders, Philip ; Bentley, Christopher ; Hilyard, Katherine ; Brown, Kevin ; Amirthalingam, Gayatri ; Charlton, Sue ; Leung, Stephanie ; Chiplin, Emily ; Coombes, Naomi S ; Bewley, Kevin R ; Penn, Elizabeth J ; Rowe, Cathy ; Otter, Ashley ; Watts, Rosie ; D'Arcangelo, Silvia ; Hallis, Bassam ; Makin, Andrew ; Richter, Alex ; Zuo, Jianmin ; Moss, Paul
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2021-09, Vol.10
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SARS-CoV-2 Disease Severity in the Golden Syrian Hamster Model of Infection Is Related to the Volume of Intranasal Inoculum
Author / Creator:Handley, Alastair ; Ryan, Kathryn A. ; Davies, Elizabeth R. ; Bewley, Kevin R. ; Carnell, Oliver T. ; Challis, Amy ; Coombes, Naomi S. ; Fotheringham, Susan A. ; Gooch, Karen E. ; Charlton, Michael ; Harris, Debbie J. ; Kennard, Chelsea ; Ngabo, Didier ; Weldon, Thomas M. ; Salguero, Francisco J. ; Funnell, Simon G. P. ; Hall, Yper
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2023-03, Vol.15 (3), p.748
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The Omicron Sub-Variant BA.4 Displays a Remarkable Lack of Clinical Signs in a Golden Syrian Hamster Model of SARS-CoV-2 Infection
Author / Creator:Davies, Elizabeth R. ; Ryan, Kathryn A. ; Bewley, Kevin R. ; Coombes, Naomi S. ; Salguero, Francisco J. ; Carnell, Oliver T. ; Biddlecombe, Sarah ; Charlton, Michael ; Challis, Amy ; Cross, Eleanor S. ; Handley, Alastair ; Ngabo, Didier ; Weldon, Thomas M. ; Hall, Yper ; Funnell, Simon G. P.
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2023-05, Vol.15 (5), p.1133
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Assessment of the Biological Impact of SARS-CoV-2 Genetic Variation Using an Authentic Virus Neutralisation Assay with Convalescent Plasma, Vaccinee Sera, and Standard Reagents
Author / Creator:Coombes, Naomi S. ; Bewley, Kevin R. ; Le Duff, Yann ; Hurley, Matthew ; Smith, Lauren J. ; Weldon, Thomas M. ; Osman, Karen ; Pullan, Steven ; Berry, Neil ; Hallis, Bassam ; Charlton, Sue ; Hall, Yper ; Funnell, Simon G. P.
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2023-02, Vol.15 (3), p.633
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ArticlesPeer ReviewedFull Text
A cautionary perspective regarding the isolation and serial propagation of SARS-CoV-2 in Vero cells
Author / Creator:Funnell, Simon G. P. ; Afrough, Babak ; Baczenas, John James ; Berry, Neil ; Bewley, Kevin R. ; Bradford, Rebecca ; Florence, Clint ; Duff, Yann Le ; Lewis, Mark ; Moriarty, Ryan V. ; Connor, Shelby L. O. ; Osman, Karen L. ; Pullan, Steven ; Rashid, Sujatha ; Richards, Kevin S. ; Stemple, Kimberly J. ; Knezevic, Ivana
Publisher:London: Nature Publishing Group UK
Journal title:npj vaccines, 2021-06, Vol.6 (1), p.83-83, Article 83
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ArticlesPeer ReviewedFull Text
Syrian hamster convalescence from prototype SARS-CoV-2 confers measurable protection against the attenuated disease caused by the Omicron variant
Author / Creator:Ryan, Kathryn A. ; Bewley, Kevin R. ; Watson, Robert J. ; Burton, Christopher ; Carnell, Oliver ; Cavell, Breeze E. ; Challis, Amy ; Coombes, Naomi S. ; Davies, Elizabeth R. ; Edun-Huges, Jack ; Emery, Kirsty ; Fell, Rachel ; Fotheringham, Susan A. ; Gooch, Karen E. ; Gowan, Kathryn ; Handley, Alastair ; Harris, Debbie J. ; Hesp, Richard ; Hunter, Laura ; Humphreys, Richard ; Johnson, Rachel ; Kennard, Chelsea ; Knott, Daniel ; Lister, Sian ; Morley, Daniel ; Ngabo, Didier ; Osman, Karen L. ; Paterson, Jemma ; Penn, Elizabeth J. ; Pullan, Steven T. ; Richards, Kevin S. ; Summers, Sian ; Thomas, Stephen R. ; Weldon, Thomas ; Wiblin, Nathan R. ; Rayner, Emma L. ; Vipond, Richard T. ; Hallis, Bassam ; Salguero, Francisco J. ; Funnell, Simon G. P. ; Hall, Yper
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2023-04, Vol.19 (4), p.e1011293-e1011293
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ArticlesFull Text
Immunological and pathological outcomes of SARS-CoV-2 challenge after formalin-inactivated vaccine immunisation of ferrets and rhesus macaques
Author / Creator:Bewley, Kevin R ; Gooch, Karen ; Thomas, Kelly M ; Longet, Stephanie ; Wiblin, Nathan ; Hunter, Laura ; Chan, Kin ; Brown, Phillip ; Russell, Rebecca A ; Ho, Catherine ; Slack, Gillian ; Humphries, Holly E ; Alden, Leonie ; Allen, Lauren ; Aram, Marilyn ; Baker, Natalie ; Brunt, Emily ; Cobb, Rebecca ; Fotheringham, Susan ; Harris, Debbie ; Kennard, Chelsea ; Leung, Stephanie ; Ryan, Kathryn ; Tolley, Howard ; Wand, Nadina ; White, Andrew ; Sibley, Laura ; Sarfas, Charlotte ; Pearson, Geoff ; Rayner, Emma ; Xue, Xiaochao ; Lambe, Teresa ; Charlton, Sue ; Gilbert, Sarah ; Sattentau, Quentin J ; Gleeson, Fergus ; Hall, Yper ; Funnell, Simon ; Sharpe, Sally ; Salguero, Francisco J ; Gorringe, Andrew ; Carroll, Miles
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-12
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ArticlesFull Text
Prophylactic intranasal administration of a TLR2 agonist reduces upper respiratory tract viral shedding in a SARS-CoV-2 challenge ferret model
Author / Creator:Proud, Pamela C ; Tsitoura, Daphne ; Watson, Robert J ; Chua, Brendon Y ; Aram, Marilyn J ; Bewley, Kevin R ; Cavell, Breeze E ; Cobb, Rebecca ; Dowall, Stuart ; Fotheringham, Susan A ; Ho, Catherine M K ; Lucas, Vanessa ; Ngabo, Didier ; Rayner, Emma ; Ryan, Kathryn A ; Slack, Gillian S ; Thomas, Stephen ; Wand, Nadina I ; Yeates, Paul ; Demaison, Christophe ; Jackson, David C ; Bartlett, Nathan W ; Mercuri, Francesca ; Carroll, Miles W
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-09
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ArticlesFull Text
Dose-dependent response to infection with SARS-CoV-2 in the ferret model: evidence of protection to re-challenge
Author / Creator:Ryan, Kathryn A ; Bewley, Kevin R ; Fotheringham, Susan A ; Brown, Phillip ; Hall, Yper ; Marriott, Anthony C ; Tree, Julia A ; Allen, Lauren ; Aram, Marilyn J ; Brunt, Emily ; Buttigieg, Karen R ; Cavell, Breeze E ; Carter, Daniel P ; Cobb, Rebecca ; Coombes, Naomi S ; Godwin, Kerry J ; Gooch, Karen E ; Gouriet, Jade ; Halkerston, Rachel ; Harris, Debbie J ; Humphries, Holly E ; Hunter, Laura ; Ho, Catherine M K ; Kennard, Chelsea L ; Leung, Stephanie ; Ngabo, Didier ; Osman, Karen L ; Paterson, Jemma ; Penn, Elizabeth J ; Pullen, Steven T ; Rayner, Emma ; Slack, Gillian S ; Steeds, Kimberley ; Taylor, Irene ; Tipton, Tom ; Thomas, Stephen ; Wand, Nadina I ; Watson, Robert J ; Wiblin, Nathan R ; Charlton, Sue ; Hallis, Bassam ; Hiscox, Julian A ; Funnell, Simon ; Dennis, Mike J ; Whittaker, Catherine J ; Catton, Michael G ; Druce, Julian ; Salguero, Francisco J ; Carroll, Miles W
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-05
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ArticlesFull Text
Comparison of Rhesus and Cynomolgus macaques as an authentic model for COVID-19
Author / Creator:Salguero, Francisco J ; White, Andrew D ; Slack, Gillian S ; Fotheringham, Susan A ; Bewley, Kevin R ; Gooch, Karen E ; Longet, Stephanie ; Humphries, Holly E ; Watson, Robert J ; Hunter, Laura ; Ryan, Kathryn A ; Hall, Yper ; Sibley, Laura ; Sarfas, Charlotte ; Allen, Lauren ; Aram, Marilyn ; Brunt, Emily ; Brown, Phillip ; Buttigieg, Karen R ; Cavell, Breeze E ; Cobb, Rebecca ; Coombes, Naomi S ; Daykin-Pont, Owen ; Elmore, Michael J ; Gkolfinos, Konstantinos ; Godwin, Kerry J ; Gouriet, Jade ; Halkerston, Rachel ; Harris, Debbie J ; Hender, Thomas ; Ho, Catherine Mk ; Kennard, Chelsea L ; Knott, Daniel ; Leung, Stephanie ; Lucas, Vanessa ; Mabbutt, Adam ; Morrison, Alexandra L ; Ngabo, Didier ; Paterson, Jemma ; Penn, Elizabeth J ; Pullan, Steve ; Taylor, Irene ; Tipton, Tom ; Thomas, Stephen ; Tree, Julia A ; Turner, Carrie ; Wand, Nadina ; Wiblin, Nathan R ; Charlton, Sue ; Hallis, Bassam ; Pearson, Geoffrey ; Rayner, Emma L ; Nicholson, Andrew G ; Funnell, Simon G ; Dennis, Mike J ; Gleeson, Fergus V ; Sharpe, Sally ; Carroll, Miles W
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-09
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Quantification of SARS-CoV-2 neutralizing antibody by wild-type plaque reduction neutralization, microneutralization and pseudotyped virus neutralization assays

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Intranasal Infection of Ferrets with SARS-CoV-2 as a Model for Asymptomatic Human Infection

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Development of immunohistochemistry and in situ hybridisation for the detection of SARS-CoV and SARS-CoV-2 in formalin-fixed paraffin-embedded specimens

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mRNA vaccination in people over 80 years of age induces strong humoral immune responses against SARS-CoV-2 with cross neutralization of P.1 Brazilian variant

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SARS-CoV-2 Disease Severity in the Golden Syrian Hamster Model of Infection Is Related to the Volume of Intranasal Inoculum

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The Omicron Sub-Variant BA.4 Displays a Remarkable Lack of Clinical Signs in a Golden Syrian Hamster Model of SARS-CoV-2 Infection

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Assessment of the Biological Impact of SARS-CoV-2 Genetic Variation Using an Authentic Virus Neutralisation Assay with Convalescent Plasma, Vaccinee Sera, and Standard Reagents

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A cautionary perspective regarding the isolation and serial propagation of SARS-CoV-2 in Vero cells

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Syrian hamster convalescence from prototype SARS-CoV-2 confers measurable protection against the attenuated disease caused by the Omicron variant

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Immunological and pathological outcomes of SARS-CoV-2 challenge after formalin-inactivated vaccine immunisation of ferrets and rhesus macaques

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Prophylactic intranasal administration of a TLR2 agonist reduces upper respiratory tract viral shedding in a SARS-CoV-2 challenge ferret model

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Dose-dependent response to infection with SARS-CoV-2 in the ferret model: evidence of protection to re-challenge

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Comparison of Rhesus and Cynomolgus macaques as an authentic model for COVID-19

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