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ArticlesPeer ReviewedFull Text
Characterization of pre-existing and induced SARS-CoV-2-specific CD8+ T cells
Author / Creator:Schulien, Isabel ; Kemming, Janine ; Oberhardt, Valerie ; Wild, Katharina ; Seidel, Lea M. ; Killmer, Saskia ; Sagar ; Daul, Franziska ; Salvat Lago, Marilyn ; Decker, Annegrit ; Luxenburger, Hendrik ; Binder, Benedikt ; Bettinger, Dominik ; Sogukpinar, Oezlem ; Rieg, Siegbert ; Panning, Marcus ; Huzly, Daniela ; Schwemmle, Martin ; Kochs, Georg ; Waller, Cornelius F. ; Nieters, Alexandra ; Duerschmied, Daniel ; Emmerich, Florian ; Mei, Henrik E. ; Schulz, Axel Ronald ; Llewellyn-Lacey, Sian ; Price, David A. ; Boettler, Tobias ; Bengsch, Bertram ; Thimme, Robert ; Hofmann, Maike ; Neumann-Haefelin, Christoph
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2021-01, Vol.27 (1), p.78-85
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Pre-existing immunity and vaccine history determine hemagglutinin-specific CD4 T cell and IgG response following seasonal influenza vaccination
Author / Creator:Wild, Katharina ; Smits, Maike ; Killmer, Saskia ; Strohmeier, Shirin ; Neumann-Haefelin, Christoph ; Bengsch, Bertram ; Krammer, Florian ; Schwemmle, Martin ; Hofmann, Maike ; Thimme, Robert ; Zoldan, Katharina ; Boettler, Tobias
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-11, Vol.12 (1), p.6720-6720, Article 6720
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Memory-like HCV-specific CD8+ T cells retain a molecular scar after cure of chronic HCV infection
Author / Creator:Hensel, Nina ; Gu, Zuguang ; Sagar ; Wieland, Dominik ; Jechow, Katharina ; Kemming, Janine ; Llewellyn-Lacey, Sian ; Gostick, Emma ; Sogukpinar, Oezlem ; Emmerich, Florian ; Price, David A. ; Bengsch, Bertram ; Boettler, Tobias ; Neumann-Haefelin, Christoph ; Eils, Roland ; Conrad, Christian ; Bartenschlager, Ralf ; Grün, Dominic ; Ishaque, Naveed ; Thimme, Robert ; Hofmann, Maike
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2021-02, Vol.22 (2), p.229-239
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HCV-Specific T Cell Responses During and After Chronic HCV Infection
Author / Creator:Luxenburger, Hendrik ; Neumann-Haefelin, Christoph ; Thimme, Robert ; Boettler, Tobias
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2018-11, Vol.10 (11), p.645
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COVID-19 mRNA booster vaccine induces transient CD8+ T effector cell responses while conserving the memory pool for subsequent reactivation
Author / Creator:Reinscheid, Matthias ; Luxenburger, Hendrik ; Karl, Vivien ; Graeser, Anne ; Giese, Sebastian ; Ciminski, Kevin ; Reeg, David B. ; Oberhardt, Valerie ; Roehlen, Natascha ; Lang-Meli, Julia ; Heim, Kathrin ; Gross, Nina ; Baum, Christina ; Rieg, Siegbert ; Speer, Claudius ; Emmerich, Florian ; Breisinger, Susanne ; Steinmann, Daniel ; Bengsch, Bertram ; Boettler, Tobias ; Kochs, Georg ; Schwemmle, Martin ; Thimme, Robert ; Neumann-Haefelin, Christoph ; Hofmann, Maike
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-08, Vol.13 (1), p.4631-11, Article 4631
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Acute pancreatitis and vasoplegic shock associated with leptospirosis – a case report and review of the literature
Author / Creator:Maier, Alexander ; Kaeser, Rafael ; Thimme, Robert ; Boettler, Tobias
Publisher:England: BioMed Central Ltd
Journal title:BMC infectious diseases, 2019-05, Vol.19 (1), p.395-395, Article 395
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Pancreatic Tissue Transplanted in TheraCyte™ Encapsulation Devices Is Protected and Prevents Hyperglycemia in a Mouse Model of Immune-Mediated Diabetes
Author / Creator:Boettler, Tobias ; Schneider, Darius ; Cheng, Yang ; Kadoya, Kuniko ; Brandon, Eugene P. ; Martinson, Laura ; Von Herrath, Matthias
Publisher:Los Angeles, CA: SAGE Publications
Journal title:Cell transplantation, 2016-03, Vol.25 (3), p.609-614
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Disentangling molecular mechanisms regulating sensitization of interferon alpha signal transduction
Author / Creator:Kok, Frédérique ; Rosenblatt, Marcus ; Teusel, Melissa ; Nizharadze, Tamar ; Gonçalves Magalhães, Vladimir ; Dächert, Christopher ; Maiwald, Tim ; Vlasov, Artyom ; Wäsch, Marvin ; Tyufekchieva, Silvana ; Hoffmann, Katrin ; Damm, Georg ; Seehofer, Daniel ; Boettler, Tobias ; Binder, Marco ; Timmer, Jens ; Schilling, Marcel ; Klingmüller, Ursula
Publisher:London: Nature Publishing Group UK
Journal title:Molecular systems biology, 2020-07, Vol.16 (7), p.1-n/a
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ArticlesPeer ReviewedFull Text
Inhibition of macrophage proliferation dominates plaque regression in response to cholesterol lowering
Author / Creator:Härdtner, Carmen ; Kornemann, Jan ; Krebs, Katja ; Ehlert, Carolin A. ; Jander, Alina ; Zou, Jiadai ; Starz, Christopher ; Rauterberg, Simon ; Sharipova, Diana ; Dufner, Bianca ; Hoppe, Natalie ; Dederichs, Tsai-Sang ; Willecke, Florian ; Stachon, Peter ; Heidt, Timo ; Wolf, Dennis ; von zur Mühlen, Constantin ; Madl, Josef ; Kohl, Peter ; Kaeser, Rafael ; Boettler, Tobias ; Pieterman, Elsbeth J. ; Princen, Hans M. G. ; Ho-Tin-Noé, Benoît ; Swirski, Filip K. ; Robbins, Clinton S. ; Bode, Christoph ; Zirlik, Andreas ; Hilgendorf, Ingo
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Basic research in cardiology, 2020-12, Vol.115 (6), p.78-78, Article 78
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ArticlesPeer ReviewedFull Text
SARS-CoV-2-specific T-cell epitope repertoire in convalescent and mRNA-vaccinated individuals
Author / Creator:Lang-Meli, Julia ; Luxenburger, Hendrik ; Wild, Katharina ; Karl, Vivien ; Oberhardt, Valerie ; Salimi Alizei, Elahe ; Graeser, Anne ; Reinscheid, Matthias ; Roehlen, Natascha ; Reeg, David B. ; Giese, Sebastian ; Ciminski, Kevin ; Götz, Veronika ; August, Dietrich ; Rieg, Siegbert ; Waller, Cornelius F. ; Wengenmayer, Tobias ; Staudacher, Dawid ; Huzly, Daniela ; Bengsch, Bertram ; Kochs, Georg ; Schwemmle, Martin ; Emmerich, Florian ; Boettler, Tobias ; Thimme, Robert ; Hofmann, Maike ; Neumann-Haefelin, Christoph
Publisher:London: Nature Publishing Group UK
Journal title:Nature microbiology, 2022-05, Vol.7 (5), p.675-679
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ArticlesPeer ReviewedFull Text
Could inherited predisposition drive non-obese fatty liver disease? Results from German tertiary referral centers
Author / Creator:Krawczyk, Marcin ; Bantel, Heike ; Rau, Monika ; Schattenberg, Jörn M. ; Grünhage, Frank ; Pathil, Anita ; Demir, Münevver ; Kluwe, Johannes ; Boettler, Tobias ; Weber, Susanne N. ; Geier, Andreas ; Lammert, Frank
Publisher:England: Nature Publishing Group
Journal title:Journal of human genetics, 2018-05, Vol.63 (5), p.621-626
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ArticlesPeer ReviewedFull Text
IL-7 receptor α blockade, an off-switch for autoreactive T cells
Author / Creator:Boettler, Tobias ; von Herrath, Matthias
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (31), p.12270-12271
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ArticlesPeer ReviewedFull Text
Tiza–Titre increase and enhanced immunity through an adjuvanted, recombinant herpes zoster subunit vaccine in patients with liver cirrhosis and post-liver transplantation: a study protocol for a prosp...
Author / Creator:Vollmer-Raschdorf, Stephanie ; Rashidi-Alavijeh, Jassin ; Voigt, Sebastian ; Hengel, Hartmut ; Borchardt, Benjamin ; Huzly, Daniela ; Hüßler, Eva-Maria ; in der Schmitten, Jürgen ; Halenius, Anne ; Willuweit, Katharina ; Botzenhardt, Suzan ; Trilling, Mirko ; Boettler, Tobias ; Dehnen, Dorothea
Publisher:London: British Medical Journal Publishing Group
Journal title:BMJ open, 2023-11, Vol.13 (11), p.e074461-e074461
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ArticlesPeer ReviewedFull Text
Hepatitis E virus as a trigger for Guillain-Barré syndrome
Author / Creator:Fritz-Weltin, Miriam ; Frommherz, Estelle ; Isenmann, Nora ; Niedermeier, Lisa ; Csernalabics, Benedikt ; Boettler, Tobias ; Neumann-Haefelin, Christoph ; Endres, Dominique ; Panning, Marcus ; Berger, Benjamin
Publisher:London: BioMed Central Ltd
Journal title:BMC neurology, 2021-08, Vol.21 (1), p.1-304, Article 304
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OX40 Facilitates Control of a Persistent Virus Infection
Author / Creator:Boettler, Tobias ; Moeckel, Friedrich ; Cheng, Yang ; Heeg, Maximilian ; Salek-Ardakani, Shahram ; Crotty, Shane ; Croft, Michael ; von Herrath, Matthias G.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2012-09, Vol.8 (9), p.e1002913-e1002913
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Survival benefit of transarterial chemoembolization in patients with metastatic hepatocellular carcinoma: a single center experience
Author / Creator:Bettinger, Dominik ; Spode, Renan ; Glaser, Nicolas ; Buettner, Nico ; Boettler, Tobias ; Neumann-Haefelin, Christoph ; Brunner, Thomas Baptist ; Gkika, Eleni ; Maruschke, Lars ; Thimme, Robert ; Schultheiss, Michael
Publisher:England: BioMed Central Ltd
Journal title:BMC gastroenterology, 2017-08, Vol.17 (1), p.98-98, Article 98
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Impaired SARS-CoV-2-Specific CD8+ T Cells After Infection or Vaccination but Robust Hybrid T Cell Immunity in Patients with Multiple Myeloma
Author / Creator:Shoumariyeh, Khalid ; Csernalabics, Benedikt ; Salimi Alizei, Elahe ; Reinscheid, Matthias ; Giese, Sebastian ; Ciminski, Kevin ; Kochs, Georg ; Schwemmle, Martin ; Lang-Meli, Julia ; Maas, Michelle ; Roehlen, Natascha ; Karl, Vivien ; Graeser, Anne ; Sogukpinar, Oezlem ; von Metzler, Ivana ; Grathwohl, Denise ; Rasche, Leo ; Hebart, Holger ; Kull, Miriam ; Emmerich, Florian ; Waller, Cornelius Florian ; Duyster, Justus ; Engelhardt, Monika ; Hartmann, Tanja Nicole ; Bengsch, Bertram ; Boettler, Tobias ; Neumann-Haefelin, Christoph ; Hofmann, Maike ; Thimme, Robert ; Luxenburger, Hendrik
Publisher:Switzerland: MDPI AG
Journal title:Vaccines (Basel), 2024-11, Vol.12 (11), p.1249
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More than shots in the dark: driving vaccine efficacy in cirrhosis
Author / Creator:Wittkop, Linda ; Boettler, Tobias
Publisher:England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title:Gut, 2024-01, Vol.73 (1), p.8-9
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Rapid and stable mobilization of CD8+ T cells by SARS-CoV-2 mRNA vaccine
Author / Creator:Oberhardt, Valerie ; Luxenburger, Hendrik ; Kemming, Janine ; Schulien, Isabel ; Ciminski, Kevin ; Giese, Sebastian ; Csernalabics, Benedikt ; Lang-Meli, Julia ; Janowska, Iga ; Staniek, Julian ; Wild, Katharina ; Basho, Kristi ; Marinescu, Mircea Stefan ; Fuchs, Jonas ; Topfstedt, Fernando ; Janda, Ales ; Sogukpinar, Oezlem ; Hilger, Hanna ; Stete, Katarina ; Emmerich, Florian ; Bengsch, Bertram ; Waller, Cornelius F. ; Rieg, Siegbert ; Sagar ; Boettler, Tobias ; Zoldan, Katharina ; Kochs, Georg ; Schwemmle, Martin ; Rizzi, Marta ; Thimme, Robert ; Neumann-Haefelin, Christoph ; Hofmann, Maike
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-09, Vol.597 (7875), p.268-273
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Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH
Author / Creator:Dudek, Michael ; Pfister, Dominik ; Donakonda, Sainitin ; Filpe, Pamela ; Schneider, Annika ; Laschinger, Melanie ; Hartmann, Daniel ; Hüser, Norbert ; Meiser, Philippa ; Bayerl, Felix ; Inverso, Donato ; Wigger, Jennifer ; Sebode, Marcial ; Öllinger, Rupert ; Rad, Roland ; Hegenbarth, Silke ; Anton, Martina ; Guillot, Adrien ; Bowman, Andrew ; Heide, Danijela ; Müller, Florian ; Ramadori, Pierluigi ; Leone, Valentina ; Garcia-Caceres, Cristina ; Gruber, Tim ; Seifert, Gabriel ; Kabat, Agnieszka M. ; Mallm, Jan-Philipp ; Reider, Simon ; Effenberger, Maria ; Roth, Susanne ; Billeter, Adrian T. ; Müller-Stich, Beat ; Pearce, Edward J. ; Koch-Nolte, Friedrich ; Käser, Rafael ; Tilg, Herbert ; Thimme, Robert ; Boettler, Tobias ; Tacke, Frank ; Dufour, Jean-Francois ; Haller, Dirk ; Murray, Peter J. ; Heeren, Ron ; Zehn, Dietmar ; Böttcher, Jan P. ; Heikenwälder, Mathias ; Knolle, Percy A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-04, Vol.592 (7854), p.444-449
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Characterization of pre-existing and induced SARS-CoV-2-specific CD8+ T cells

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Pre-existing immunity and vaccine history determine hemagglutinin-specific CD4 T cell and IgG response following seasonal influenza vaccination

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Memory-like HCV-specific CD8+ T cells retain a molecular scar after cure of chronic HCV infection

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HCV-Specific T Cell Responses During and After Chronic HCV Infection

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COVID-19 mRNA booster vaccine induces transient CD8+ T effector cell responses while conserving the memory pool for subsequent reactivation

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Acute pancreatitis and vasoplegic shock associated with leptospirosis – a case report and review of the literature

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Pancreatic Tissue Transplanted in TheraCyte™ Encapsulation Devices Is Protected and Prevents Hyperglycemia in a Mouse Model of Immune-Mediated Diabetes

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Disentangling molecular mechanisms regulating sensitization of interferon alpha signal transduction

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Inhibition of macrophage proliferation dominates plaque regression in response to cholesterol lowering

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SARS-CoV-2-specific T-cell epitope repertoire in convalescent and mRNA-vaccinated individuals

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Could inherited predisposition drive non-obese fatty liver disease? Results from German tertiary referral centers

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IL-7 receptor α blockade, an off-switch for autoreactive T cells

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Tiza–Titre increase and enhanced immunity through an adjuvanted, recombinant herpes zoster subunit vaccine in patients with liver cirrhosis and post-liver transplantation: a study protocol for a prosp...

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Hepatitis E virus as a trigger for Guillain-Barré syndrome

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OX40 Facilitates Control of a Persistent Virus Infection

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Survival benefit of transarterial chemoembolization in patients with metastatic hepatocellular carcinoma: a single center experience

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Impaired SARS-CoV-2-Specific CD8+ T Cells After Infection or Vaccination but Robust Hybrid T Cell Immunity in Patients with Multiple Myeloma

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More than shots in the dark: driving vaccine efficacy in cirrhosis

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Rapid and stable mobilization of CD8+ T cells by SARS-CoV-2 mRNA vaccine

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Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH

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