Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH
Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH
About this item
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Author / Creator
Dudek, Michael , Pfister, Dominik , Donakonda, Sainitin , Filpe, Pamela , Schneider, Annika , Laschinger, Melanie , Hartmann, Daniel , Hüser, Norbert , Meiser, Philippa , Bayerl, Felix , Inverso, Donato , Wigger, Jennifer , Sebode, Marcial , Öllinger, Rupert , Rad, Roland , Hegenbarth, Silke , Anton, Martina , Guillot, Adrien , Bowman, Andrew , Heide, Danijela , Müller, Florian , Ramadori, Pierluigi , Leone, Valentina , Garcia-Caceres, Cristina , Gruber, Tim , Seifert, Gabriel , Kabat, Agnieszka M. , Mallm, Jan-Philipp , Reider, Simon , Effenberger, Maria , Roth, Susanne , Billeter, Adrian T. , Müller-Stich, Beat , Pearce, Edward J. , Koch-Nolte, Friedrich , Käser, Rafael , Tilg, Herbert , Thimme, Robert , Boettler, Tobias , Tacke, Frank , Dufour, Jean-Francois , Haller, Dirk , Murray, Peter J. , Heeren, Ron , Zehn, Dietmar , Böttcher, Jan P. , Heikenwälder, Mathias and Knolle, Percy A.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Nonalcoholic steatohepatitis (NASH) is a manifestation of systemic metabolic disease related to obesity, and causes liver disease and cancer
1
,
2
. The accumulation of metabolites leads to cell stress and inflammation in the liver
3
, but mechanistic understandings of liver damage in NASH are incomplete. Here, using a preclinical...
Alternative Titles
Full title
Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH
Authors, Artists and Contributors
Author / Creator
Pfister, Dominik
Donakonda, Sainitin
Filpe, Pamela
Schneider, Annika
Laschinger, Melanie
Hartmann, Daniel
Hüser, Norbert
Meiser, Philippa
Bayerl, Felix
Inverso, Donato
Wigger, Jennifer
Sebode, Marcial
Öllinger, Rupert
Rad, Roland
Hegenbarth, Silke
Anton, Martina
Guillot, Adrien
Bowman, Andrew
Heide, Danijela
Müller, Florian
Ramadori, Pierluigi
Leone, Valentina
Garcia-Caceres, Cristina
Gruber, Tim
Seifert, Gabriel
Kabat, Agnieszka M.
Mallm, Jan-Philipp
Reider, Simon
Effenberger, Maria
Roth, Susanne
Billeter, Adrian T.
Müller-Stich, Beat
Pearce, Edward J.
Koch-Nolte, Friedrich
Käser, Rafael
Tilg, Herbert
Thimme, Robert
Boettler, Tobias
Tacke, Frank
Dufour, Jean-Francois
Haller, Dirk
Murray, Peter J.
Heeren, Ron
Zehn, Dietmar
Böttcher, Jan P.
Heikenwälder, Mathias
Knolle, Percy A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2505358202
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2505358202
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-021-03233-8
