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ArticlesPeer ReviewedFull Text
Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance
Author / Creator:Lebeau, Paul F. ; Byun, Jae Hyun ; Platko, Khrystyna ; Saliba, Paul ; Sguazzin, Matthew ; MacDonald, Melissa E. ; Paré, Guillaume ; Steinberg, Gregory R. ; Janssen, Luke J. ; Igdoura, Suleiman A. ; Tarnopolsky, Mark A. ; Wayne Chen, S. R. ; Seidah, Nabil G. ; Magolan, Jakob ; Austin, Richard C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-02, Vol.13 (1), p.770-770, Article 770
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ArticlesPeer ReviewedFull Text
The Emerging Roles of Intracellular PCSK9 and Their Implications in Endoplasmic Reticulum Stress and Metabolic Diseases
Author / Creator:Lebeau, Paul F ; Platko, Khrystyna ; Byun, Jae Hyun ; Makda, Yumna ; Austin, Richard C
Publisher:Switzerland: MDPI AG
Journal title:Metabolites, 2022-02, Vol.12 (3), p.215
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ArticlesPeer ReviewedFull Text
Scratching the Surface-An Overview of the Roles of Cell Surface GRP78 in Cancer
Author / Creator:Chen, Jack ; Lynn, Edward G ; Yousof, Tamana R ; Sharma, Hitesh ; MacDonald, Melissa E ; Byun, Jae Hyun ; Shayegan, Bobby ; Austin, Richard C
Publisher:Switzerland: MDPI AG
Journal title:Biomedicines, 2022-05, Vol.10 (5), p.1098
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ArticlesPeer ReviewedFull Text
Long-Term Outcomes of Resynchronization–Defibrillation for Heart Failure
Author / Creator:Byun, Jae Hyun ; Nguyen, Sissi ; Pintea Bentea, Georgiana ; Castro Rodriguez, Jose ; Sapp, John L. ; Sivakumaran, Soori ; Tang, Anthony S.L.
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2024-04, Vol.390 (14), p.1343-1345
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ArticlesPeer ReviewedFull Text
Development of a Pumpless Microfluidic System to Study the Interaction between Gut Microbes and Intestinal Epithelial Cells
Author / Creator:Lee, Seung Yeon ; Byun, Hyun Jae ; Choi, Heelak ; Won, Jong-In ; Han, Jeonghun ; Park, Sungsu ; Kim, Donghyun ; Sung, Jong Hwan
Publisher:Seoul: The Korean Society for Biotechnology and Bioengineering
Journal title:Biotechnology and Bioprocess Engineering, 2022, 27(2), , pp.221-233
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ArticlesPeer ReviewedFull Text
The loss-of-function PCSK9Q152H variant increases ER chaperones GRP78 and GRP94 and protects against liver injury
Author / Creator:Lebeau, Paul F ; Wassef, Hanny ; Byun, Jae Hyun ; Platko, Khrystyna ; Ason, Brandon ; Jackson, Simon ; Dobroff, Joshua ; Shetterly, Susan ; Richards, William G ; Al-Hashimi, Ali A ; Won, Kevin Doyoon ; Mbikay, Majambu ; Prat, Annik ; Tang, An ; Paré, Guillaume ; Pasqualini, Renata ; Seidah, Nabil G ; Arap, Wadih ; Chrétien, Michel ; Austin, Richard C
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2021-01, Vol.131 (2), p.1-14
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ArticlesPeer ReviewedFull Text
The loss-of-function PCSK[9.sup.Q152H] variant increases ER chaperones GRP78 and GRP94 and protects against liver injury
Author / Creator:Lebeau, Paul F ; Wassef, Hanny ; Byun, Jae Hyun ; Platko, Khrystyna ; Ason, Brandon ; Jackson, Simon ; Dobroff, Joshua ; Shetterly, Susan ; Richards, William G ; Al-Hashimi, Ali A ; Won, Kevin Doyoon ; Mbikay, Majambu ; Prat, Annik ; Tang, An ; Pare, Guillaume ; Pasqualini, Renata ; Seidah, Nabil G ; Arap, Wadih ; Chretien, Michel ; Austin, Richard C
Publisher:American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2021-01, Vol.131 (2)
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ArticlesPeer ReviewedFull Text
A Metabolic Enhancer Protects against Diet-Induced Obesity and Liver Steatosis and Corrects a Pro-Atherogenic Serum Profile in Mice
Author / Creator:Platko, Khrystyna ; Lebeau, Paul F ; Nederveen, Joshua P ; Byun, Jae Hyun ; MacDonald, Melissa E ; Bourgeois, Jacqueline M ; Tarnopolsky, Mark A ; Austin, Richard C
Publisher:Switzerland: MDPI AG
Journal title:Nutrients, 2023-05, Vol.15 (10), p.2410
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ReportsFull Text
The loss-of-function PCSK[9.sup.Q152H] variant increases ER chaperones GRP78 and GRP94 and protects against liver injury
Author / Creator:Lebeau, Paul F ; Wassef, Hanny ; Byun, Jae Hyun ; Platko, Khrystyna ; Ason, Brandon ; Jackson, Simon ; Dobroff, Joshua ; Shetterly, Susan ; Richards, William G ; Al-Hashimi, Ali A ; Won, Kevin Doyoon ; Mbikay, Majambu ; Prat, Annik ; Tang, An ; Pare, Guillaume ; Pasqualini, Renata ; Seidah, Nabil G ; Arap, Wadih ; Chretien, Michel ; Austin, Richard C
Publisher:American Society for Clinical Investigation
Journal title:Journal of Clinical Investigation, 2021, Vol.131 (2)
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ReportsFull Text
The loss-of-function PCSK[9.sup.Q152H] variant increases ER chaperones GRP78 and GRP94 and protects against liver injury
Author / Creator:Lebeau, Paul F ; Wassef, Hanny ; Byun, Jae Hyun ; Platko, Khrystyna ; Ason, Brandon ; Jackson, Simon ; Dobroff, Joshua ; Shetterly, Susan ; Richards, William G ; Al-Hashimi, Ali A ; Won, Kevin Doyoon ; Mbikay, Majambu ; Prat, Annik ; Tang, An ; Pare, Guillaume ; Pasqualini, Renata ; Seidah, Nabil G ; Arap, Wadih ; Chretien, Michel ; Austin, Richard C
Publisher:American Society for Clinical Investigation
Journal title:Journal of Clinical Investigation, 2021, Vol.131 (2)
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Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance

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The Emerging Roles of Intracellular PCSK9 and Their Implications in Endoplasmic Reticulum Stress and Metabolic Diseases

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Scratching the Surface-An Overview of the Roles of Cell Surface GRP78 in Cancer

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Long-Term Outcomes of Resynchronization–Defibrillation for Heart Failure

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Development of a Pumpless Microfluidic System to Study the Interaction between Gut Microbes and Intestinal Epithelial Cells

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The loss-of-function PCSK9Q152H variant increases ER chaperones GRP78 and GRP94 and protects against liver injury

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The loss-of-function PCSK[9.sup.Q152H] variant increases ER chaperones GRP78 and GRP94 and protects against liver injury

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A Metabolic Enhancer Protects against Diet-Induced Obesity and Liver Steatosis and Corrects a Pro-Atherogenic Serum Profile in Mice

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The loss-of-function PCSK[9.sup.Q152H] variant increases ER chaperones GRP78 and GRP94 and protects against liver injury

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The loss-of-function PCSK[9.sup.Q152H] variant increases ER chaperones GRP78 and GRP94 and protects against liver injury

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