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ArticlesPeer ReviewedFull Text
Tumor immunotherapies by immune checkpoint inhibitors (ICIs); the pros and cons
Author / Creator:Naimi, Adel ; Mohammed, Rebar N. ; Raji, Ahmed ; Chupradit, Supat ; Yumashev, Alexei Valerievich ; Suksatan, Wanich ; Shalaby, Mohammed Nader ; Thangavelu, Lakshmi ; Kamrava, Siavash ; Shomali, Navid ; Sohrabi, Armin D. ; Adili, Ali ; Noroozi-Aghideh, Ali ; Razeghian, Ehsan
Publisher:England: BioMed Central
Journal title:Cell communication and signaling, 2022-04, Vol.20 (1), p.44-31, Article 44
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Regulatory T (Treg) cells in cancer: Can Treg cells be a new therapeutic target?
Author / Creator:Ohue, Yoshihiro ; Nishikawa, Hiroyoshi
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2019-07, Vol.110 (7), p.2080-2089
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Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
Author / Creator:Tekguc, Murat ; Wing, James Badger ; Osaki, Motonao ; Long, Jia ; Sakaguchi, Shimon
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-07, Vol.118 (30), p.1-12
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Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation
Author / Creator:Kennedy, Alan ; Waters, Erin ; Rowshanravan, Behzad ; Hinze, Claudia ; Williams, Cayman ; Janman, Daniel ; Fox, Thomas A ; Booth, Claire ; Pesenacker, Anne M ; Halliday, Neil ; Soskic, Blagoje ; Kaur, Satdip ; Qureshi, Omar S ; Morris, Emma C ; Ikemizu, Shinji ; Paluch, Christopher ; Huo, Jiandong ; Davis, Simon J ; Boucrot, Emmanuel ; Walker, Lucy S. K ; Sansom, David M
Publisher:New York: Nature Publishing Group
Journal title:Nature immunology, 2022-09, Vol.23 (9), p.1365-1378
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Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer
Author / Creator:Coutzac, Clélia ; Jouniaux, Jean-Mehdi ; Paci, Angelo ; Schmidt, Julien ; Mallardo, Domenico ; Seck, Atmane ; Asvatourian, Vahe ; Cassard, Lydie ; Saulnier, Patrick ; Lacroix, Ludovic ; Woerther, Paul-Louis ; Vozy, Aurore ; Naigeon, Marie ; Nebot-Bral, Laetitia ; Desbois, Mélanie ; Simeone, Ester ; Mateus, Christine ; Boselli, Lisa ; Grivel, Jonathan ; Soularue, Emilie ; Lepage, Patricia ; Carbonnel, Franck ; Ascierto, Paolo Antonio ; Robert, Caroline ; Chaput, Nathalie
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-05, Vol.11 (1), p.2168-13, Article 2168
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Intermittent theta-burst stimulation improves motor function by inhibiting neuronal pyroptosis and regulating microglial polarization via TLR4/NFκB/NLRP3 signaling pathway in cerebral ischemic mice
Author / Creator:Luo, Lu ; Liu, Meixi ; Fan, Yunhui ; Zhang, Jingjun ; Liu, Li ; Li, Yun ; Zhang, Qiqi ; Xie, Hongyu ; Jiang, Congyu ; Wu, Junfa ; Xiao, Xiao ; Wu, Yi
Publisher:England: BioMed Central
Journal title:Journal of neuroinflammation, 2022-06, Vol.19 (1), p.141-27, Article 141
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Peripheral immunophenotypes in children with multisystem inflammatory syndrome associated with SARS-CoV-2 infection
Author / Creator:Carter, Michael J. ; Fish, Matthew ; Jennings, Aislinn ; Doores, Katie J. ; Wellman, Paul ; Seow, Jeffrey ; Acors, Sam ; Graham, Carl ; Timms, Emma ; Kenny, Julia ; Neil, Stuart ; Malim, Michael H. ; Tibby, Shane M. ; Shankar-Hari, Manu
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2020-11, Vol.26 (11), p.1701-1707
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Inflammation promotes resistance to immune checkpoint inhibitors in high microsatellite instability colorectal cancer
Author / Creator:Sui, Qiaoqi ; Zhang, Xi ; Chen, Chao ; Tang, Jinghua ; Yu, Jiehai ; Li, Weihao ; Han, Kai ; Jiang, Wu ; Liao, Leen ; Kong, Lingheng ; Li, Yuan ; Hou, Zhenlin ; Zhou, Chi ; Zhang, Chenzhi ; Zhang, Linjie ; Xiao, Binyi ; Mei, Weijian ; Xu, Yanbo ; Qin, Jiayi ; Zheng, Jian ; Pan, Zhizhong ; Ding, Pei-Rong
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-11, Vol.13 (1), p.7316-11, Article 7316
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Formation of a protein corona on the surface of extracellular vesicles in blood plasma
Author / Creator:Tóth, Eszter Á. ; Turiák, Lilla ; Visnovitz, Tamás ; Cserép, Csaba ; Mázló, Anett ; Sódar, Barbara W. ; Försönits, András I. ; Petővári, Gábor ; Sebestyén, Anna ; Komlósi, Zsolt ; Drahos, László ; Kittel, Ágnes ; Nagy, György ; Bácsi, Attila ; Dénes, Ádám ; Gho, Yong Song ; Szabó‐Taylor, Katalin É. ; Buzás, Edit I.
Publisher:United States: John Wiley & Sons, Inc
Journal title:Journal of extracellular vesicles, 2021-09, Vol.10 (11), p.e12140-n/a
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Identification of a novel arthritis-associated osteoclast precursor macrophage regulated by FoxM1
Author / Creator:Hasegawa, Tetsuo ; Kikuta, Junichi ; Sudo, Takao ; Matsuura, Yoshinobu ; Matsui, Takahiro ; Simmons, Szandor ; Ebina, Kosuke ; Hirao, Makoto ; Okuzaki, Daisuke ; Yoshida, Yuichi ; Hirao, Atsushi ; Kalinichenko, Vladimir V. ; Yamaoka, Kunihiro ; Takeuchi, Tsutomu ; Ishii, Masaru
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2019-12, Vol.20 (12), p.1631-1643
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Applications of nanotechnology for immunology
Author / Creator:Smith, Douglas M. ; Simon, Jakub K. ; Baker Jr, James R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Immunology, 2013-08, Vol.13 (8), p.592-605
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Identification of novel protein biomarkers and drug targets for colorectal cancer by integrating human plasma proteome with genome
Author / Creator:Sun, Jing ; Zhao, Jianhui ; Jiang, Fangyuan ; Wang, Lijuan ; Xiao, Qian ; Han, Fengyan ; Chen, Jie ; Yuan, Shuai ; Wei, Jingsun ; Larsson, Susanna C. ; Zhang, Honghe ; Dunlop, Malcolm G ; Farrington, Susan M ; Ding, Kefeng ; Theodoratou, Evropi ; Li, Xue
Publisher:England: BioMed Central Ltd
Journal title:Genome medicine, 2023-09, Vol.15 (1), p.75-13, Article 75
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Efficient Targeting and Activation of Antigen-Presenting Cells In Vivo after Modified mRNA Vaccine Administration in Rhesus Macaques
Author / Creator:Liang, Frank ; Lindgren, Gustaf ; Lin, Ang ; Thompson, Elizabeth A. ; Ols, Sebastian ; Röhss, Josefine ; John, Shinu ; Hassett, Kimberly ; Yuzhakov, Olga ; Bahl, Kapil ; Brito, Luis A. ; Salter, Hugh ; Ciaramella, Giuseppe ; Loré, Karin
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2017-12, Vol.25 (12), p.2635-2647
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Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
Author / Creator:Mikami, Norihisa ; Kawakami, Ryoji ; Chen, Kelvin Y. ; Sugimoto, Atsushi ; Ohkura, Naganari ; Sakaguchi, Shimon
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-06, Vol.117 (22), p.12258-12268
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Inhibition of EZH2 induces NK cell-mediated differentiation and death in muscle-invasive bladder cancer
Author / Creator:Ramakrishnan Swathi ; Granger, Victoria ; Rak Monika ; Hu, Qiang ; Attwood Kristopher ; Aquila Lanni ; Krishnan Nithya ; Osiecki Rafal ; Azabdaftari Gissou ; Khurshid, Guru ; Chatta Gurkamal ; Gueron Geraldine ; McNally Lacey ; Ohm, Joyce ; Wang, Jianmin ; Woloszynska Anna
Publisher:Rome: Nature Publishing Group
Journal title:Cell death and differentiation, 2019-10, Vol.26 (10), p.2100-2114
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An anti-CTLA-4 heavy chain–only antibody with enhanced Treg depletion shows excellent preclinical efficacy and safety profile
Author / Creator:Gan, Xin ; Shan, Qianqian ; Li, He ; Janssens, Rick ; Shen, Yuqiang ; He, Yun ; Chen, Fei ; van Haperen, Rien ; Drabek, Dubravka ; Li, Jin ; Zhang, Yang ; Zhao, Jiuqiao ; Qin, Beibei ; Jheng, Ming-Jin ; Chen, Victor ; Wang, Jingsong ; Rong, Yiping ; Grosveld, Frank
Publisher:Washington: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2022-08, Vol.119 (32), p.1-10
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Cell iron status influences macrophage polarization
Author / Creator:Agoro, Rafiou ; Taleb, Meriem ; Quesniaux, Valerie F. J. ; Mura, Catherine
Publisher:United States: Public Library of Science
Journal title:PloS one, 2018-05, Vol.13 (5), p.e0196921
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Impaired function and delayed regeneration of dendritic cells in COVID-19
Author / Creator:Winheim, Elena ; Rinke, Linus ; Lutz, Konstantin ; Reischer, Anna ; Leutbecher, Alexandra ; Wolfram, Lina ; Rausch, Lisa ; Kranich, Jan ; Wratil, Paul R. ; Huber, Johanna E. ; Baumjohann, Dirk ; Rothenfusser, Simon ; Schubert, Benjamin ; Hilgendorff, Anne ; Hellmuth, Johannes C. ; Scherer, Clemens ; Muenchhoff, Maximilian ; von Bergwelt-Baildon, Michael ; Stark, Konstantin ; Straub, Tobias ; Brocker, Thomas ; Keppler, Oliver T. ; Subklewe, Marion ; Krug, Anne B.
Publisher:San Francisco: Public Library of Science (PLoS)
Journal title:PLOS Pathogens, 2021-10, Vol.17 (10), p.e1009742
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Priming of microglia with IFN-γ slows neuronal gamma oscillations in situ
Author / Creator:Ta, Thuy-Truc ; Dikmen, Hasan Onur ; Schilling, Simone ; Chausse, Bruno ; Lewen, Andrea ; Hollnagel, Jan-Oliver ; Kann, Oliver
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-03, Vol.116 (10), p.4637-4642
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Increase in circulating cells coexpressing M1 and M2 macrophage surface markers in patients with systemic sclerosis
Author / Creator:Soldano, Stefano ; Trombetta, Amelia Chiara ; Contini, Paola ; Tomatis, Veronica ; Ruaro, Barbara ; Brizzolara, Renata ; Montagna, Paola ; Sulli, Alberto ; Paolino, Sabrina ; Pizzorni, Carmen ; Smith, Vanessa ; Cutolo, Maurizio
Publisher:England: Elsevier Limited
Journal title:Annals of the rheumatic diseases, 2018-12, Vol.77 (12), p.1842-1845
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Tumor immunotherapies by immune checkpoint inhibitors (ICIs); the pros and cons

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Regulatory T (Treg) cells in cancer: Can Treg cells be a new therapeutic target?

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Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells

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Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation

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Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer

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Intermittent theta-burst stimulation improves motor function by inhibiting neuronal pyroptosis and regulating microglial polarization via TLR4/NFκB/NLRP3 signaling pathway in cerebral ischemic mice

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Peripheral immunophenotypes in children with multisystem inflammatory syndrome associated with SARS-CoV-2 infection

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Inflammation promotes resistance to immune checkpoint inhibitors in high microsatellite instability colorectal cancer

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Formation of a protein corona on the surface of extracellular vesicles in blood plasma

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Identification of a novel arthritis-associated osteoclast precursor macrophage regulated by FoxM1

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Applications of nanotechnology for immunology

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Identification of novel protein biomarkers and drug targets for colorectal cancer by integrating human plasma proteome with genome

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Efficient Targeting and Activation of Antigen-Presenting Cells In Vivo after Modified mRNA Vaccine Administration in Rhesus Macaques

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Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation

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Inhibition of EZH2 induces NK cell-mediated differentiation and death in muscle-invasive bladder cancer

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An anti-CTLA-4 heavy chain–only antibody with enhanced Treg depletion shows excellent preclinical efficacy and safety profile

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Cell iron status influences macrophage polarization

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Impaired function and delayed regeneration of dendritic cells in COVID-19

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Priming of microglia with IFN-γ slows neuronal gamma oscillations in situ

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Increase in circulating cells coexpressing M1 and M2 macrophage surface markers in patients with systemic sclerosis

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