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ArticlesPeer ReviewedFull Text
Integrated multiomics and Mendelian randomization identify CHIT1 as a novel sepsis biomarker and therapeutic target
Author / Creator:Li, Guorui ; Mao, Yunlong ; Liao, Jiaxiang ; Zhou, Yuquan
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-05, Vol.15 (1), p.15715-17, Article 15715
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CHIT1 at diagnosis predicts faster disability progression and reflects early microglial activation in multiple sclerosis
Author / Creator:Beliën, Jarne ; Swinnen, Stijn ; D’hondt, Robbe ; Verdú de Juan, Laia ; Dedoncker, Nina ; Matthys, Patrick ; Bauer, Jan ; Vens, Celine ; Moylett, Sinéad ; Dubois, Bénédicte
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-06, Vol.15 (1), p.5013-15, Article 5013
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Chitotriosidase (CHIT1) is increased in microglia and macrophages in spinal cord of amyotrophic lateral sclerosis and cerebrospinal fluid levels correlate with disease severity and progression
Author / Creator:Steinacker, Petra ; Verde, Federico ; Fang, Lubin ; Feneberg, Emily ; Oeckl, Patrick ; Roeber, Sigrun ; Anderl-Straub, Sarah ; Danek, Adrian ; Diehl-Schmid, Janine ; Fassbender, Klaus ; Fliessbach, Klaus ; Foerstl, Hans ; Giese, Armin ; Jahn, Holger ; Kassubek, Jan ; Kornhuber, Johannes ; Landwehrmeyer, G Bernhard ; Lauer, Martin ; Pinkhardt, Elmar Hans ; Prudlo, Johannes ; Rosenbohm, Angela ; Schneider, Anja ; Schroeter, Matthias L ; Tumani, Hayrettin ; von Arnim, Christine A F ; Weishaupt, Jochen ; Weydt, Patrick ; Ludolph, Albert C ; Yilmazer Hanke, Deniz ; Otto, Markus
Publisher:England: BMJ Publishing Group LTD
Journal title:Journal of neurology, neurosurgery and psychiatry, 2018-03, Vol.89 (3), p.239-247
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Prognostic relationship of neurofilaments, CHIT1, YKL-40 and MCP-1 in amyotrophic lateral sclerosis
Author / Creator:Masrori, Pegah ; De Schaepdryver, Maxim ; Floeter, Mary Kay ; De Vocht, Joke ; Lamaire, Nikita ; D'Hondt, Ann ; Traynor, Bryan ; Poesen, Koen ; Van Damme, Philip
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal of neurology, neurosurgery and psychiatry, 2022-06, Vol.93 (6), p.681-682
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Inhibition of Macrophage-Specific CHIT1 as an Approach to Treat Airway Remodeling in Severe Asthma
Author / Creator:Sklepkiewicz, Piotr ; Dymek, Barbara ; Mlacki, Michal ; Zagozdzon, Agnieszka ; Salamon, Magdalena ; Siwińska, Anna Maria ; Mazurkiewicz, Marcin Piotr ; de Souza Xavier Costa, Natalia ; Mazur, Marzena ; Mauad, Thais ; Gołębiowski, Adam ; Dzwonek, Karolina ; Gołąb, Jakub ; Zasłona, Zbigniew
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2023-03, Vol.24 (5), p.4719
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Pharmacological Inhibition of Chitotriosidase (CHIT1) as a Novel Therapeutic Approach for Sarcoidosis Pharmacological Inhibition of Chitotriosidase (CHIT1) as a Novel Therapeutic Approach for Sarcoido...
Author / Creator:Dymek B ; Sklepkiewicz P ; Mlacki M ; Güner NC ; Nejman-Gryz P ; Drzewicka K ; Przysucha N ; Rymaszewska A ; Paplinska-Goryca M ; Zagozdzon A ; Proboszcz M ; Krzemiński Ł ; von der Thüsen JH ; Górska K ; Dzwonek K ; Zasłona Z ; Dobrzanski P ; Krenke R
Publisher:Dove Medical Press
Journal title:Journal of inflammation research, 2022-09, Vol.15, p.5621-5634
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PLA2G2D and CHIT1: Potential biomarkers for immune infiltration and prognosis in cervical squamous cell carcinoma
Author / Creator:Jiang, Liangliang ; Qiao, Qiushuang ; Wang, Jing
Publisher:Harbin: De Gruyter
Journal title:Frigid Zone Medicine (Warsaw. Online), 2024-07, Vol.4 (2), p.110-119
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Expression of CHI3L1 and CHIT1 in osteoarthritic rat cartilage model. A morphological study
Author / Creator:Di Rosa, M. ; Szychlinska, M.A. ; Tibullo, D. ; Malaguarnera, L. ; Musumeci, G.
Publisher:Italy: PAGEPress Publications
Journal title:European journal of histochemistry, 2014-09, Vol.58 (3), p.2423-2423
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Exploratory Longitudinal Analysis of the Circulating CHIT1 Activity in Pediatric Patients with Obesity
Author / Creator:Țaranu, Ioana ; Răcătăianu, Nicoleta ; Drugan, Cristina ; Cătană, Cristina-Sorina ; Mirea, Andreea-Manuela ; Miclea, Diana ; Bolboacă, Sorana D.
Publisher:Switzerland: MDPI AG
Journal title:Children (Basel), 2023-01, Vol.10 (1), p.124
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ArticlesPeer ReviewedFull Text
X-Ray Crystal Structure of the Full Length Human Chitotriosidase (CHIT1) Reveals Features of Its Chitin Binding Domain
Author / Creator:Fadel, Firas ; Zhao, Yuguang ; Cousido-Siah, Alexandra ; Ruiz, Francesc X. ; Mitschler, André ; Podjarny, Alberto
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-04, Vol.11 (4), p.e0154190-e0154190
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Pharmacological Inhibition of Chitotriosidase (CHIT1) as a Novel Therapeutic Approach for Sarcoidosis
Author / Creator:Dymek, Barbara ; Sklepkiewicz, Piotr ; Mlacki, Michal ; Güner, Nazan Cemre ; Nejman-Gryz, Patrycja ; Drzewicka, Katarzyna ; Przysucha, Natalia ; Rymaszewska, Aleksandra ; Paplinska-Goryca, Magdalena ; Zagozdzon, Agnieszka ; Proboszcz, Małgorzata ; Krzemiński, Łukasz ; von der Thüsen, Jan H ; Górska, Katarzyna ; Dzwonek, Karolina ; Zasłona, Zbigniew ; Dobrzanski, Pawel ; Krenke, Rafał
Publisher:Macclesfield: Dove Medical Press Limited
Journal title:Journal of inflammation research, 2022-01, Vol.15, p.5621-5634
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Allele frequency of a 24 bp duplication in exon 10 of the CHIT1 gene in the general Korean population and in Korean patients with Gaucher disease
Author / Creator:Woo, Kyu Ha ; Lee, Beom Hee ; Heo, Sun Hee ; Kim, Jae-Min ; Kim, Gu-Hwan ; Kim, Yoo-Mi ; Kim, Ja Hye ; Choi, In-Hee ; Yang, Song Hyun ; Yoo, Han-Wook
Publisher:England: Nature Publishing Group
Journal title:Journal of human genetics, 2014-05, Vol.59 (5), p.276-279
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ArticlesPeer ReviewedFull Text
Obesity modulates the association between sleep apnea treatment and CHI3L1 levels but not CHIT1 activity in moderate to severe OSA: an observational study
Author / Creator:Teitsdottir, Unnur Dilja ; Arnardottir, Erna Sif ; Bjornsdottir, Erla ; Gislason, Thorarinn ; Petersen, Petur Henry
Publisher:Cham: Springer International Publishing
Journal title:Sleep & breathing, 2018-12, Vol.22 (4), p.1101-1109
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Nasal Microbiome Composition Is Associated with Chitotriosidase (Chit1) Activity in Adult Hutterites
Author / Creator:Igartua, Catherine ; Davenport, Emily R. ; Chupp, Geoff L. ; Elias, Jack A. ; Gilad, Yoav ; Ober, Carole ; Pinto, Jayant M.
Publisher:United States: American Thoracic Society
Journal title:Annals of the American Thoracic Society, 2016-03, Vol.13 (Supplement 1), p.S100-S101
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An Alternative Macrophage Activation Pathway Regulator, CHIT1, May Provide a Serum and Synovial Fluid Biomarker of Periprosthetic Osteolysis
Author / Creator:Trehan, Samir K. ; Zambrana, Lester ; Jo, Jonathan E. ; Purdue, Ed ; Karamitros, Athanos ; Nguyen, Joseph T. ; Lane, Joseph M.
Publisher:Los Angeles, CA: SAGE Publications
Journal title:HSS journal, 2018-07, Vol.14 (2), p.148-152
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C46 OBESITY INFLUENCES ON THE LUNG: Chitotriosidase (chit1) Regulates Lung Inflammation And Obesity
Author / Creator:Ahangari, F ; Takyar, S ; Lee, C G ; Elias, J A
Publisher:New York: American Thoracic Society
Journal title:American journal of respiratory and critical care medicine, 2014-01, Vol.189, p.1
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Association of 24 bp Duplication of Human CHIT1 Gene with Asthma in a Heterozygous Population of North India: A Case–Control Study
Author / Creator:Sinha, Shweta ; Singh, Jagtar ; Jindal, Surinder Kumar ; Birbian, Niti ; Singla, Neha
Publisher:New York: Springer US
Journal title:Lung, 2014-10, Vol.192 (5), p.685-691
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A62 LUNG FIBROSIS: FIBROBLAST BIOLOGY: Chitinase 1 (chit1) Stimulates Tgf-[Beta]1 Signaling In The Lung Fibroblasts Via Interaction With Tgf-[Beta]1-Receptor Associate Protein 1 (tgfrap1)
Author / Creator:Lee, C-M ; He, C-H ; Lee, C ; Elias, J A
Publisher:New York: American Thoracic Society
Journal title:American journal of respiratory and critical care medicine, 2014-01, Vol.189, p.1
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Chitinases and Chitinase-Like Proteins in Obstructive Lung Diseases - Current Concepts and Potential Applications Chitinases and Chitinase-Like Proteins in Obstructive Lung Diseases - Current Concepts...
Author / Creator:Przysucha N ; Górska K ; Krenke R
Publisher:Dove Medical Press
Journal title:International journal of chronic obstructive pulmonary disease, 2020-04, Vol.15, p.885-899
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Different neuroinflammatory profile in amyotrophic lateral sclerosis and frontotemporal dementia is linked to the clinical phase
Author / Creator:Oeckl, Patrick ; Weydt, Patrick ; Steinacker, Petra ; Anderl-Straub, Sarah ; Nordin, Frida ; Volk, Alexander E ; Diehl-Schmid, Janine ; Andersen, Peter M ; Kornhuber, Johannes ; Danek, Adrian ; Fassbender, Klaus ; Fliessbach, Klaus ; Jahn, Holger ; Lauer, Martin ; Müller, Kathrin ; Knehr, Antje ; Prudlo, Johannes ; Schneider, Anja ; Thal, Dietmar R ; Yilmazer-Hanke, Deniz ; Weishaupt, Jochen H ; Ludolph, Albert C ; Otto, Markus
Publisher:England: BMJ Publishing Group LTD
Journal title:Journal of neurology, neurosurgery and psychiatry, 2019-01, Vol.90 (1), p.4-10
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Showing 1 to 20 of 143 results

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Integrated multiomics and Mendelian randomization identify CHIT1 as a novel sepsis biomarker and therapeutic target

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CHIT1 at diagnosis predicts faster disability progression and reflects early microglial activation in multiple sclerosis

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Chitotriosidase (CHIT1) is increased in microglia and macrophages in spinal cord of amyotrophic lateral sclerosis and cerebrospinal fluid levels correlate with disease severity and progression

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Prognostic relationship of neurofilaments, CHIT1, YKL-40 and MCP-1 in amyotrophic lateral sclerosis

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Inhibition of Macrophage-Specific CHIT1 as an Approach to Treat Airway Remodeling in Severe Asthma

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Pharmacological Inhibition of Chitotriosidase (CHIT1) as a Novel Therapeutic Approach for Sarcoidosis Pharmacological Inhibition of Chitotriosidase (CHIT1) as a Novel Therapeutic Approach for Sarcoido...

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PLA2G2D and CHIT1: Potential biomarkers for immune infiltration and prognosis in cervical squamous cell carcinoma

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Expression of CHI3L1 and CHIT1 in osteoarthritic rat cartilage model. A morphological study

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Exploratory Longitudinal Analysis of the Circulating CHIT1 Activity in Pediatric Patients with Obesity

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X-Ray Crystal Structure of the Full Length Human Chitotriosidase (CHIT1) Reveals Features of Its Chitin Binding Domain

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Pharmacological Inhibition of Chitotriosidase (CHIT1) as a Novel Therapeutic Approach for Sarcoidosis

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Allele frequency of a 24 bp duplication in exon 10 of the CHIT1 gene in the general Korean population and in Korean patients with Gaucher disease

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Obesity modulates the association between sleep apnea treatment and CHI3L1 levels but not CHIT1 activity in moderate to severe OSA: an observational study

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Nasal Microbiome Composition Is Associated with Chitotriosidase (Chit1) Activity in Adult Hutterites

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An Alternative Macrophage Activation Pathway Regulator, CHIT1, May Provide a Serum and Synovial Fluid Biomarker of Periprosthetic Osteolysis

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C46 OBESITY INFLUENCES ON THE LUNG: Chitotriosidase (chit1) Regulates Lung Inflammation And Obesity

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Association of 24 bp Duplication of Human CHIT1 Gene with Asthma in a Heterozygous Population of North India: A Case–Control Study

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A62 LUNG FIBROSIS: FIBROBLAST BIOLOGY: Chitinase 1 (chit1) Stimulates Tgf-[Beta]1 Signaling In The Lung Fibroblasts Via Interaction With Tgf-[Beta]1-Receptor Associate Protein 1 (tgfrap1)

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Chitinases and Chitinase-Like Proteins in Obstructive Lung Diseases - Current Concepts and Potential Applications Chitinases and Chitinase-Like Proteins in Obstructive Lung Diseases - Current Concepts...

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Different neuroinflammatory profile in amyotrophic lateral sclerosis and frontotemporal dementia is linked to the clinical phase

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