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34 results for CTLA-4+Antigen+-+therapeutic+use

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ArticlesPeer ReviewedFull Text
Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial
Author / Creator:Weber, Jeffrey S, Dr ; D'Angelo, Sandra P, MD ; Minor, David, MD ; Hodi, F Stephen, MD ; Gutzmer, Ralf, MD ; Neyns, Bart, MD ; Hoeller, Christoph, MD ; Khushalani, Nikhil I, MD ; Miller, Wilson H, MD ; Lao, Christopher D, MD ; Linette, Gerald P, MD ; Thomas, Luc, MD ; Lorigan, Paul, FRCP ; Grossmann, Kenneth F, MD ; Hassel, Jessica C, MD ; Maio, Michele, MD ; Sznol, Mario, MD ; Ascierto, Paolo A, MD ; Mohr, Peter, MD ; Chmielowski, Bartosz, MD ; Bryce, Alan, MD ; Svane, Inge M, MD ; Grob, Jean-Jacques, MD ; Krackhardt, Angela M, MD ; Horak, Christine, PhD ; Lambert, Alexandre, PhD ; Yang, Arvin S, MD ; Larkin, James, FRCP
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2015-04, Vol.16 (4), p.375-384
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Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis
Author / Creator:Wang, Yinghong ; Wiesnoski, Diana H. ; Helmink, Beth A. ; Gopalakrishnan, Vancheswaran ; Choi, Kati ; DuPont, Hebert L. ; Jiang, Zhi-Dong ; Abu-Sbeih, Hamzah ; Sanchez, Christopher A. ; Chang, Chia-Chi ; Parra, Edwin R. ; Francisco-Cruz, Alejandro ; Raju, Gottumukkala S. ; Stroehlein, John R. ; Campbell, Matthew T. ; Gao, Jianjun ; Subudhi, Sumit K. ; Maru, Dipen M. ; Blando, Jorge M. ; Lazar, Alexander J. ; Allison, James P. ; Sharma, Padmanee ; Tetzlaff, Michael T. ; Wargo, Jennifer A. ; Jenq, Robert R.
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2018-12, Vol.24 (12), p.1804-1808
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The gut microbiota influences anticancer immunosurveillance and general health
Author / Creator:Routy, Bertrand ; Gopalakrishnan, Vancheswaran ; Daillère, Romain ; Zitvogel, Laurence ; Wargo, Jennifer A. ; Kroemer, Guido
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Clinical oncology, 2018-06, Vol.15 (6), p.382-396
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Therapeutic targets and biomarkers of tumor immunotherapy: response versus non-response
Author / Creator:Wang, Dong-Rui ; Wu, Xian-Lin ; Sun, Ying-Li
Publisher:London: Nature Publishing Group UK
Journal title:Signal transduction and targeted therapy, 2022-09, Vol.7 (1), p.331-27, Article 331
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TLR1/2 ligand enhances antitumor efficacy of CTLA-4 blockade by increasing intratumoral Treg depletion
Author / Creator:Sharma, Naveen ; Vacher, Jean ; Allison, James P.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-05, Vol.116 (21), p.10453-10462
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Immune checkpoint inhibitors: an emerging cause of insulin-dependent diabetes
Author / Creator:Kotwal, Anupam ; Haddox, Candace ; Block, Matthew ; Kudva, Yogish C
Publisher:England: American Diabetes Association
Journal title:BMJ open diabetes research & care, 2019-02, Vol.7 (1), p.e000591-e000591
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Combined CTLA-4 and PD-L1 blockade in patients with chemotherapy-naïve metastatic castration-resistant prostate cancer is associated with increased myeloid and neutrophil immune subsets in the bone mi...
Author / Creator:Subudhi, Sumit K ; Siddiqui, Bilal A ; Aparicio, Ana M ; Yadav, Shalini S ; Basu, Sreyashi ; Chen, Hong ; Jindal, Sonali ; Tidwell, Rebecca S S ; Varma, Ashwin ; Logothetis, Christopher J ; Allison, James P ; Corn, Paul G ; Sharma, Padmanee
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2021-10, Vol.9 (10), p.e002919
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Targeting CTLA-4: a possible solution for microsatellite-stable colorectal cancer
Author / Creator:Ghiringhelli, François ; Thibaudin, Marion
Publisher:London: Nature Publishing Group UK
Journal title:Genes and immunity, 2023-12, Vol.24 (6), p.283-284
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Metastatic melanoma: can FDG-PET predict success of anti-PD-1 therapy and help determine when it can be discontinued?
Author / Creator:Hindié, Elif
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:European journal of nuclear medicine and molecular imaging, 2020-09, Vol.47 (10), p.2227-2232
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ArticlesPeer ReviewedFull Text
Case series: CTLA4-IgG1 therapy in minimal change disease and focal segmental glomerulosclerosis
Author / Creator:Garin, Eduardo H. ; Reiser, Jochen ; Cara-Fuentes, Gabriel ; Wei, Changli ; Matar, Dany ; Wang, Heiman ; Alachkar, Nada ; Johnson, Richard J.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Pediatric nephrology (Berlin, West), 2015-03, Vol.30 (3), p.469-477
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ArticlesPeer ReviewedFull Text
Immune checkpoint inhibitor-associated acute kidney injury in patients with cancer: a systematic review and meta-analysis of risk factors
Author / Creator:Yan, Haoyu ; Tang, Meimei ; Zhu, Wei ; Yang, Yiqun
Publisher:Singapore: Springer Nature Singapore
Journal title:Clinical and experimental nephrology, 2023-07, Vol.27 (7), p.603-612
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ArticlesPeer ReviewedFull Text
Phase I trial of KN046, a novel bispecific antibody targeting PD-L1 and CTLA-4 in patients with advanced solid tumors
Author / Creator:Ma, Yuxiang ; Xue, Jinhui ; Zhao, Yuanyuan ; Zhang, Yang ; Huang, Yan ; Yang, Yunpeng ; Fang, Wenfeng ; Guo, Ye ; Li, Qun ; Ge, Xiaoxiao ; Sun, Jie ; Zhang, Bangyong ; Zhang, Yuhan ; Xiao, Jinyuan ; Zhang, Li ; Zhao, Hongyun
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2023-06, Vol.11 (6), p.e006654
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ArticlesPeer ReviewedFull Text
Combining intratumoral Treg depletion with androgen deprivation therapy (ADT): preclinical activity in the Myc-CaP model
Author / Creator:Shen, Ying-Chun ; Ghasemzadeh, Ali ; Kochel, Christina M. ; Nirschl, Thomas R. ; Francica, Brian J. ; Lopez-Bujanda, Zoila A. ; Carrera Haro, Maria A. ; Tam, Ada ; Anders, Robert A. ; Selby, Mark J. ; Korman, Alan J. ; Drake, Charles G.
Publisher:London: Nature Publishing Group UK
Journal title:Prostate cancer and prostatic diseases, 2018-04, Vol.21 (1), p.113-125
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ArticlesPeer ReviewedFull Text
Digital spatial proteomic profiling reveals immune checkpoints as biomarkers in lymphoid aggregates and tumor microenvironment of desmoplastic melanoma
Author / Creator:Su, David G ; Schoenfeld, David A. ; Ibrahim, Wael ; Cabrejo, Raysa ; Djureinovic, Dijana ; Baumann, Raymond ; Rimm, David L ; Khan, Sajid A ; Halaban, Ruth ; Kluger, Harriet M ; Olino, Kelly ; Galan, Anjela ; Clune, James
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2024-03, Vol.12 (3), p.e008646
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ArticlesPeer ReviewedFull Text
Impact of radiotherapy and sequencing of systemic therapy on survival outcomes in melanoma patients with previously untreated brain metastasis: a multicenter DeCOG study on 450 patients from the prosp...
Author / Creator:Franklin, Cindy ; Mohr, Peter ; Bluhm, Leonie ; Grimmelmann, Imke ; Gutzmer, Ralf ; Meier, Friedegund ; Garzarolli, Marlene ; Weichenthal, Michael ; Pfoehler, Claudia ; Herbst, Rudolf ; Terheyden, Patrick ; Utikal, Jochen ; Ulrich, Jens ; Debus, Dirk ; Haferkamp, Sebastian ; Kaatz, Martin ; Forschner, Andrea ; Leiter, Ulrike ; Nashan, Dorothee ; Kreuter, Alexander ; Sachse, Michael ; Welzel, Julia ; Heinzerling, Lucie ; Meiss, Frank ; Weishaupt, Carsten ; Gambichler, Thilo ; Weyandt, Gerhard ; Dippel, Edgar ; Schatton, Kerstin ; Celik, Eren ; Trommer, Maike ; Helfrich, Iris ; Roesch, Alexander ; Zimmer, Lisa ; Livingstone, Elisabeth ; Schadendorf, Dirk ; Horn, Susanne ; Ugurel, Selma
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2022-06, Vol.10 (6), p.e004509
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Combining immune check-point blockade and cryoablation in an immunocompetent hormone sensitive murine model of prostate cancer
Author / Creator:Benzon, Benjamin ; Glavaris, Stephanie A. ; Simons, Brian W. ; Hughes, Robert M. ; Ghabili, Kamyar ; Mullane, Patrick ; Miller, Rebecca ; Nugent, Katriana ; Shinder, Brian ; Tosoian, Jeffrey ; Fuchs, Ephraim J. ; Tran, Phuoc T. ; Hurley, Paula J. ; Vuica-Ross, Milena ; Schaeffer, Edward M. ; Drake, Charles G. ; Ross, Ashley E.
Publisher:London: Nature Publishing Group UK
Journal title:Prostate cancer and prostatic diseases, 2018-04, Vol.21 (1), p.126-136
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Combining CTLA-4 and angiopoietin-2 blockade in patients with advanced melanoma: a phase I trial
Author / Creator:Ott, Patrick A ; Nazzaro, Matthew ; Pfaff, Kathleen L ; Gjini, Evisa ; Felt, Kristen D ; Wolff, Jacquelyn O ; Buchbinder, Elizabeth I ; Haq, Rizwan ; Sullivan, Ryan J ; Lawrence, Donald P ; McDermott, David F ; Severgnini, Mariano ; Giobbie-Hurder, Anita ; Rodig, Scott J ; Stephen Hodi, F
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2021-11, Vol.9 (11), p.e003318
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ArticlesPeer ReviewedFull Text
Evaluation of pd-1, pd-l1, and cytotoxic T-lymphocyteassociated protein 4 expressions together with clinicopathological findings in clear cell, papillary, and chromophobe types of renal cell carcinoma
Author / Creator:Inceman, Merve ; Toyran, Tugba ; Bayazit, Yildirim ; Izol, Volkan ; Erdogan, Seyda
Publisher:Poland: Termedia Publishing House
Journal title:Polish journal of pathology, 2022, Vol.73 (3), p.181-190
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Evaluation of tumor microenvironment and biomarkers of immune checkpoint inhibitor response in metastatic renal cell carcinoma
Author / Creator:Brown, Landon C ; Zhu, Jason ; Desai, Kunal ; Kinsey, Emily ; Kao, Chester ; Lee, Yong Hee ; Pabla, Sarabjot ; Labriola, Matthew K ; Tran, Jennifer ; Dragnev, Konstantin H ; Tafe, Laura J ; Dayyani, Farshid ; Gupta, Rajan T ; McCall, Shannon ; George, Daniel J ; Glenn, Sean T ; Nesline, Mary K ; George, Saby ; Zibelman, Matthew ; Morrison, Carl ; Ornstein, Moshe C ; Zhang, Tian
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2022-10, Vol.10 (10), p.e005249
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ArticlesPeer ReviewedFull Text
Diabetic ketoacidosis shortly after COVID‐19 vaccination in a non–small‐cell lung cancer patient receiving combination of PD‐1 and CTLA‐4 inhibitors: A case report
Author / Creator:Makiguchi, Tomonori ; Fukushima, Takashi ; Tanaka, Hisashi ; Taima, Kageaki ; Takayasu, Shinobu ; Tasaka, Sadatomo
Publisher:Melbourne: John Wiley & Sons Australia, Ltd
Journal title:Thoracic cancer, 2022-04, Vol.13 (8), p.1220-1223
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Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial

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Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis

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The gut microbiota influences anticancer immunosurveillance and general health

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Therapeutic targets and biomarkers of tumor immunotherapy: response versus non-response

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TLR1/2 ligand enhances antitumor efficacy of CTLA-4 blockade by increasing intratumoral Treg depletion

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Immune checkpoint inhibitors: an emerging cause of insulin-dependent diabetes

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Combined CTLA-4 and PD-L1 blockade in patients with chemotherapy-naïve metastatic castration-resistant prostate cancer is associated with increased myeloid and neutrophil immune subsets in the bone mi...

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Targeting CTLA-4: a possible solution for microsatellite-stable colorectal cancer

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Metastatic melanoma: can FDG-PET predict success of anti-PD-1 therapy and help determine when it can be discontinued?

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Case series: CTLA4-IgG1 therapy in minimal change disease and focal segmental glomerulosclerosis

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Immune checkpoint inhibitor-associated acute kidney injury in patients with cancer: a systematic review and meta-analysis of risk factors

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Phase I trial of KN046, a novel bispecific antibody targeting PD-L1 and CTLA-4 in patients with advanced solid tumors

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Combining intratumoral Treg depletion with androgen deprivation therapy (ADT): preclinical activity in the Myc-CaP model

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Digital spatial proteomic profiling reveals immune checkpoints as biomarkers in lymphoid aggregates and tumor microenvironment of desmoplastic melanoma

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Impact of radiotherapy and sequencing of systemic therapy on survival outcomes in melanoma patients with previously untreated brain metastasis: a multicenter DeCOG study on 450 patients from the prosp...

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Combining immune check-point blockade and cryoablation in an immunocompetent hormone sensitive murine model of prostate cancer

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Combining CTLA-4 and angiopoietin-2 blockade in patients with advanced melanoma: a phase I trial

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Evaluation of pd-1, pd-l1, and cytotoxic T-lymphocyteassociated protein 4 expressions together with clinicopathological findings in clear cell, papillary, and chromophobe types of renal cell carcinoma

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Evaluation of tumor microenvironment and biomarkers of immune checkpoint inhibitor response in metastatic renal cell carcinoma

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Diabetic ketoacidosis shortly after COVID‐19 vaccination in a non–small‐cell lung cancer patient receiving combination of PD‐1 and CTLA‐4 inhibitors: A case report

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