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313 results for Caspase+9+-+genetics

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ArticlesPeer ReviewedFull Text
GD2-CART01 for Relapsed or Refractory High-Risk Neuroblastoma
Author / Creator:Del Bufalo, Francesca ; De Angelis, Biagio ; Caruana, Ignazio ; Del Baldo, Giada ; De Ioris, Maria A. ; Serra, Annalisa ; Mastronuzzi, Angela ; Cefalo, Maria G. ; Pagliara, Daria ; Amicucci, Matteo ; Li Pira, Giuseppina ; Leone, Giovanna ; Bertaina, Valentina ; Sinibaldi, Matilde ; Di Cecca, Stefano ; Guercio, Marika ; Abbaszadeh, Zeinab ; Iaffaldano, Laura ; Gunetti, Monica ; Iacovelli, Stefano ; Bugianesi, Rossana ; Macchia, Stefania ; Algeri, Mattia ; Merli, Pietro ; Galaverna, Federica ; Abbas, Rachid ; Garganese, Maria C. ; Villani, Maria F. ; Colafati, Giovanna S. ; Bonetti, Federico ; Rabusin, Marco ; Perruccio, Katia ; Folsi, Veronica ; Quintarelli, Concetta ; Locatelli, Franco
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2023-04, Vol.388 (14), p.1284-1295
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A split-Cas9 architecture for inducible genome editing and transcription modulation
Author / Creator:Zetsche, Bernd ; Volz, Sara E ; Zhang, Feng
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2015-02, Vol.33 (2), p.139-142
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Multiplex and homologous recombination–mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9
Author / Creator:Li, Jian-Feng ; Norville, Julie E ; Aach, John ; McCormack, Matthew ; Zhang, Dandan ; Bush, Jenifer ; Church, George M ; Sheen, Jen
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2013-08, Vol.31 (8), p.688-691
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New insights into apoptosome structure and function
Author / Creator:Dorstyn, Loretta ; Akey, Christopher W. ; Kumar, Sharad
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2018-07, Vol.25 (7), p.1194-1208
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Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy
Author / Creator:Di Stasi, Antonio ; Tey, Siok-Keen ; Dotti, Gianpietro ; Fujita, Yuriko ; Kennedy-Nasser, Alana ; Martinez, Caridad ; Straathof, Karin ; Liu, Enli ; Liu, Hao ; Durett, April G ; Grilley, Bambi ; Cruz, Conrad R ; Savoldo, Barbara ; Gee, Adrian P ; Schindler, John ; Krance, Robert A ; Heslop, Helen E ; Spencer, David M ; Rooney, Cliona M ; Brenner, Malcolm K
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2011-11, Vol.365 (18), p.1673-1683
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AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC
Author / Creator:Sagulenko, V ; Thygesen, S J ; Sester, D P ; Idris, A ; Cridland, J A ; Vajjhala, P R ; Roberts, T L ; Schroder, K ; Vince, J E ; Hill, J M ; Silke, J ; Stacey, K J
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2013-09, Vol.20 (9), p.1149-1160
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Tumor cells suppress radiation-induced immunity by hijacking caspase 9 signaling
Author / Creator:Han, Chuanhui ; Liu, Zhida ; Zhang, Yunjia ; Shen, Aijun ; Dong, Chunbo ; Zhang, Anli ; Moore, Casey ; Ren, Zhenhua ; Lu, Changzheng ; Cao, Xuezhi ; Zhang, Chun-Li ; Qiao, Jian ; Fu, Yang-Xin
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2020-05, Vol.21 (5), p.546-554
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Mechanistic insights into caspase-9 activation by the structure of the apoptosome holoenzyme
Author / Creator:Li, Yini ; Zhou, Mengying ; Hu, Qi ; 胡奇 ; Bai, Xiao-chen ; Huang, Weiyun ; Scheres, Sjors H. W. ; Shi, Yigong ; 施一公
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-02, Vol.114 (7), p.1542-1547
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Rapidly inducible Cas9 and DSB-ddPCR to probe editing kinetics
Author / Creator:Rose, John C ; Stephany, Jason J ; Valente, William J ; Trevillian, Bridget M ; Dang, Ha V ; Bielas, Jason H ; Maly, Dustin J ; Fowler, Douglas M
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2017-09, Vol.14 (9), p.891-896
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RapaCaspase-9-based suicide gene applied to the safety of IL-1RAP CAR-T cells
Author / Creator:Bouquet, Lucie ; Bôle-Richard, Elodie ; Warda, Walid ; Neto Da Rocha, Mathieu ; Trad, Rim ; Nicod, Clémentine ; Haderbache, Rafik ; Genin, Delphine ; Ferrand, Christophe ; Deschamps, Marina
Publisher:London: Nature Publishing Group UK
Journal title:Gene therapy, 2023-09, Vol.30 (9), p.706-713
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Apoptotic and predictive factors by Bax, Caspases 3/9, Bcl-2, p53 and Ki-67 in prostate cancer after 12 Gy single-dose
Author / Creator:Pisani, Carla ; Ramella, Martina ; Boldorini, Renzo ; Loi, Gianfranco ; Billia, Michele ; Boccafoschi, Francesca ; Volpe, Alessandro ; Krengli, Marco
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-04, Vol.10 (1), p.7050-7050, Article 7050
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Combining a CD20 Chimeric Antigen Receptor and an Inducible Caspase 9 Suicide Switch to Improve the Efficacy and Safety of T Cell Adoptive Immunotherapy for Lymphoma
Author / Creator:Budde, Lihua E. ; Berger, Carolina ; Lin, Yukang ; Wang, Jinjuan ; Lin, Xubin ; Frayo, Shani E. ; Brouns, Shaunda A. ; Spencer, David M. ; Till, Brian G. ; Jensen, Michael C. ; Riddell, Stanley R. ; Press, Oliver W.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-12, Vol.8 (12), p.e82742
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Caspase 9-induced apoptosis enables efficient fetal cell ablation and disease modeling
Author / Creator:Matsui, Kenji ; Watanabe, Masahito ; Yamamoto, Shutaro ; Kawagoe, Shiho ; Ikeda, Takumi ; Ohashi, Hinari ; Kuroda, Takafumi ; Koda, Nagisa ; Morimoto, Keita ; Kinoshita, Yoshitaka ; Inage, Yuka ; Saito, Yatsumu ; Fukunaga, Shohei ; Fujimoto, Toshinari ; Tajiri, Susumu ; Matsumoto, Kei ; Kobayashi, Eiji ; Yokoo, Takashi ; Yamanaka, Shuichiro
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-03, Vol.16 (1), p.2572-18, Article 2572
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Splicing factor proline- and glutamine-rich (SFPQ) protein regulates platinum response in ovarian cancer-modulating SRSF2 activity
Author / Creator:Pellarin, Ilenia ; Dall’Acqua, Alessandra ; Gambelli, Alice ; Pellizzari, Ilenia ; D’Andrea, Sara ; Sonego, Maura ; Lorenzon, Ilaria ; Schiappacassi, Monica ; Belletti, Barbara ; Baldassarre, Gustavo
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2020-05, Vol.39 (22), p.4390-4403
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Oncogenic miR-96-5p inhibits apoptosis by targeting the caspase-9 gene in hepatocellular carcinoma
Author / Creator:Iwai, Naoto ; Yasui, Kohichiroh ; Tomie, Akira ; Gen, Yasuyuki ; Terasaki, Kei ; Kitaichi, Tomoko ; Soda, Tomohiro ; Yamada, Nobuhisa ; Dohi, Osamu ; Seko, Yuya ; Umemura, Atsushi ; Nishikawa, Taichiro ; Yamaguchi, Kanji ; Moriguchi, Michihisa ; Konishi, Hideyuki ; Naito, Yuji ; Itoh, Yoshito
Publisher:Athens: Spandidos Publications
Journal title:International journal of oncology, 2018-07, Vol.53 (1), p.237-245
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Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their anti-lymphoma/leukemia effects and safety
Author / Creator:Hoyos, V ; Savoldo, B ; Quintarelli, C ; Mahendravada, A ; Zhang, M ; Vera, J ; Heslop, H E ; Rooney, C M ; Brenner, M K ; Dotti, G
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2010-06, Vol.24 (6), p.1160-1170
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Ameliorative Effect of Fisetin on Cisplatin-Induced Nephrotoxicity in Rats via Modulation of NF-κB Activation and Antioxidant Defence
Author / Creator:Sahu, Bidya Dhar ; Kalvala, Anil Kumar ; Koneru, Meghana ; Mahesh Kumar, Jerald ; Kuncha, Madhusudana ; Rachamalla, Shyam Sunder ; Sistla, Ramakrishna
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014, Vol.9 (9), p.e105070
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Mechanism of piperine in affecting apoptosis and proliferation of gastric cancer cells via ROS‐mitochondria‐associated signalling pathway
Author / Creator:Guo, Li ; Yang, Yi ; Sheng, YongJia ; Wang, Jin ; Ruan, Shuiliang ; Han, Chenyang
Publisher:England: John Wiley & Sons, Inc
Journal title:Journal of cellular and molecular medicine, 2021-10, Vol.25 (20), p.9513-9522
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Caspase selective reagents for diagnosing apoptotic mechanisms
Author / Creator:Poreba, Marcin ; Groborz, Katarzyna ; Navarro, Mario ; Snipas, Scott J. ; Drag, Marcin ; Salvesen, Guy S.
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2019-02, Vol.26 (2), p.229-244
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Genome-Wide Association and Functional Follow-Up Reveals New Loci for Kidney Function
Author / Creator:Pattaro, Cristian ; Köttgen, Anna ; Teumer, Alexander ; Garnaas, Maija ; Böger, Carsten A. ; Fuchsberger, Christian ; Olden, Matthias ; Chen, Ming-Huei ; Tin, Adrienne ; Taliun, Daniel ; Li, Man ; Gao, Xiaoyi ; Gorski, Mathias ; Yang, Qiong ; Hundertmark, Claudia ; Foster, Meredith C. ; O'Seaghdha, Conall M. ; Glazer, Nicole ; Isaacs, Aaron ; Liu, Ching-Ti ; Smith, Albert V. ; O'Connell, Jeffrey R. ; Struchalin, Maksim ; Tanaka, Toshiko ; Li, Guo ; Johnson, Andrew D. ; Gierman, Hinco J. ; Feitosa, Mary ; Hwang, Shih-Jen ; Atkinson, Elizabeth J. ; Lohman, Kurt ; Cornelis, Marilyn C. ; Johansson, Åsa ; Tönjes, Anke ; Dehghan, Abbas ; Chouraki, Vincent ; Holliday, Elizabeth G. ; Sorice, Rossella ; Kutalik, Zoltan ; Lehtimäki, Terho ; Esko, Tõnu ; Deshmukh, Harshal ; Ulivi, Sheila ; Chu, Audrey Y. ; Murgia, Federico ; Trompet, Stella ; Imboden, Medea ; Kollerits, Barbara ; Pistis, Giorgio ; Harris, Tamara B. ; Launer, Lenore J. ; Aspelund, Thor ; Eiriksdottir, Gudny ; Mitchell, Braxton D. ; Boerwinkle, Eric ; Schmidt, Helena ; Cavalieri, Margherita ; Rao, Madhumathi ; Hu, Frank B. ; Demirkan, Ayse ; Oostra, Ben A. ; de Andrade, Mariza ; Turner, Stephen T. ; Ding, Jingzhong ; Andrews, Jeanette S. ; Freedman, Barry I. ; Koenig, Wolfgang ; Illig, Thomas ; Döring, Angela ; Wichmann, H.-Erich ; Kolcic, Ivana ; Zemunik, Tatijana ; Boban, Mladen ; Minelli, Cosetta ; Wheeler, Heather E. ; Igl, Wilmar ; Zaboli, Ghazal ; Wild, Sarah H. ; Wright, Alan F. ; Campbell, Harry ; Ellinghaus, David ; Nöthlings, Ute ; Jacobs, Gunnar ; Biffar, Reiner ; Endlich, Karlhans ; Ernst, Florian ; Homuth, Georg ; Kroemer, Heyo K. ; Nauck, Matthias ; Stracke, Sylvia ; Völker, Uwe ; Völzke, Henry ; Kovacs, Peter ; Stumvoll, Michael ; Mägi, Reedik ; Hofman, Albert ; Uitterlinden, Andre G. ; Rivadeneira, Fernando ; Aulchenko, Yurii S. ; Polasek, Ozren
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2012-03, Vol.8 (3), p.e1002584
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GD2-CART01 for Relapsed or Refractory High-Risk Neuroblastoma

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A split-Cas9 architecture for inducible genome editing and transcription modulation

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Multiplex and homologous recombination–mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9

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New insights into apoptosome structure and function

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Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy

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AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC

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Tumor cells suppress radiation-induced immunity by hijacking caspase 9 signaling

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Mechanistic insights into caspase-9 activation by the structure of the apoptosome holoenzyme

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Rapidly inducible Cas9 and DSB-ddPCR to probe editing kinetics

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RapaCaspase-9-based suicide gene applied to the safety of IL-1RAP CAR-T cells

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Apoptotic and predictive factors by Bax, Caspases 3/9, Bcl-2, p53 and Ki-67 in prostate cancer after 12 Gy single-dose

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Combining a CD20 Chimeric Antigen Receptor and an Inducible Caspase 9 Suicide Switch to Improve the Efficacy and Safety of T Cell Adoptive Immunotherapy for Lymphoma

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Caspase 9-induced apoptosis enables efficient fetal cell ablation and disease modeling

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Splicing factor proline- and glutamine-rich (SFPQ) protein regulates platinum response in ovarian cancer-modulating SRSF2 activity

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Oncogenic miR-96-5p inhibits apoptosis by targeting the caspase-9 gene in hepatocellular carcinoma

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Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their anti-lymphoma/leukemia effects and safety

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Ameliorative Effect of Fisetin on Cisplatin-Induced Nephrotoxicity in Rats via Modulation of NF-κB Activation and Antioxidant Defence

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Mechanism of piperine in affecting apoptosis and proliferation of gastric cancer cells via ROS‐mitochondria‐associated signalling pathway

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Caspase selective reagents for diagnosing apoptotic mechanisms

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Genome-Wide Association and Functional Follow-Up Reveals New Loci for Kidney Function

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