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29 results for Caspase+Inhibitors+-+chemistry

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Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor
Author / Creator:Yang, Jie ; Liu, Zhonghua ; Wang, Chuanping ; Yang, Rui ; Rathkey, Joseph K. ; Pinkard, Otis W. ; Shi, Wuxian ; Chen, Yinghua ; Dubyak, George R. ; Abbott, Derek W. ; Xiao, Tsan Sam
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-06, Vol.115 (26), p.6792-6797
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Study of Caspase 8 Inhibition for the Management of Alzheimer’s Disease: A Molecular Docking and Dynamics Simulation
Author / Creator:Ahmad, Syed Sayeed ; Sinha, Meetali ; Ahmad, Khurshid ; Khalid, Mohammad ; Choi, Inho
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2020-04, Vol.25 (9), p.2071
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The Selective 3-MST Inhibitor I3MT-3 Works as a Potent Caspase-1 Inhibitor
Author / Creator:Otani, Kohei ; Komatsu, Ryuto ; Noguchi, Takuya ; Suzuki, Wakana ; Hirata, Yusuke ; Matsuzawa, Atsushi
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2025-03, Vol.26 (5), p.2237
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Caspase selective reagents for diagnosing apoptotic mechanisms
Author / Creator:Poreba, Marcin ; Groborz, Katarzyna ; Navarro, Mario ; Snipas, Scott J. ; Drag, Marcin ; Salvesen, Guy S.
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2019-02, Vol.26 (2), p.229-244
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Gasdermin E-derived caspase-3 inhibitors effectively protect mice from acute hepatic failure
Author / Creator:Xu, Wan-feng ; Zhang, Quan ; Ding, Chu-jie ; Sun, Hui-yong ; Che, Yuan ; Huang, Hai ; Wang, Yun ; Wu, Jia-wei ; Hao, Hai-ping ; Cao, Li-juan
Publisher:Singapore: Springer Singapore
Journal title:Acta pharmacologica Sinica, 2021-01, Vol.42 (1), p.68-76
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Specific covalent inhibition of MALT1 paracaspase suppresses B cell lymphoma growth
Author / Creator:Fontán, Lorena ; Qiao, Qi ; Hatcher, John M. ; Casalena, Gabriella ; Us, Ilkay ; Teater, Matt ; Durant, Matt ; Du, Guangyan ; Xia, Min ; Bilchuk, Natalia ; Chennamadhavuni, Spandan ; Palladino, Giuseppe ; Inghirami, Giorgio ; Philippar, Ulrike ; Wu, Hao ; Scott, David A. ; Gray, Nathanael S. ; Melnick, Ari
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2018-10, Vol.128 (10), p.4397-4412
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Synthesis, Characterization, and In Vivo Study of Some Novel 3,4,5-Trimethoxybenzylidene-hydrazinecarbothioamides and Thiadiazoles as Anti-Apoptotic Caspase-3 Inhibitors
Author / Creator:Mostafa, Sara M. ; Aly, Ashraf A. ; Bräse, Stefan ; Nieger, Martin ; Abdelhafez, Sara Mohamed Naguib ; Abdelzaher, Walaa Yehia ; Abdelhafez, El-Shimaa M. N.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-03, Vol.27 (7), p.2266
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Design, Synthesis, Molecular Docking, Antiapoptotic and Caspase-3 Inhibition of New 1,2,3-Triazole/Bis-2(1H)-Quinolinone Hybrids
Author / Creator:El-Sheref, Essmat M. ; Aly, Ashraf A. ; Alshammari, Mohammed B. ; Brown, Alan B. ; Abdel-Hafez, Sara Mohamed Naguib ; Abdelzaher, Walaa Yehia ; Bräse, Stefan ; Abdelhafez, ElShimaa M. N.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2020-10, Vol.25 (21), p.5057
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A Fluorescence-Polarization-Based Lipopolysaccharide–Caspase-4 Interaction Assay for the Development of Inhibitors
Author / Creator:An, Jinsu ; Kim, So Yeon ; Yang, Eun Gyeong ; Chung, Hak Suk
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-04, Vol.27 (8), p.2458
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The E. coli Effector Protein NleF Is a Caspase Inhibitor
Author / Creator:Blasche, Sonja ; Mörtl, Mario ; Steuber, Holger ; Siszler, Gabriella ; Nisa, Shahista ; Schwarz, Frank ; Lavrik, Inna ; Gronewold, Thomas M. A. ; Maskos, Klaus ; Donnenberg, Michael S. ; Ullmann, Dirk ; Uetz, Peter ; Kögl, Manfred
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-03, Vol.8 (3), p.e58937
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Mechanism of Caspase-1 Inhibition by Four Anti-inflammatory Drugs Used in COVID-19 Treatment
Author / Creator:Caruso, Francesco ; Pedersen, Jens Z. ; Incerpi, Sandra ; Kaur, Sarjit ; Belli, Stuart ; Florea, Radu-Mihai ; Rossi, Miriam
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2022-02, Vol.23 (3), p.1849
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Implication of Caspase-3 as a Common Therapeutic Target for Multineurodegenerative Disorders and Its Inhibition Using Nonpeptidyl Natural Compounds
Author / Creator:Haque, Shafiul ; Lohani, Mohtashim ; Baig, Mohd. Hassan ; Adnan, Mohd ; Alshammari, Eyad M. A. ; Ahmad, Khurshid ; Khan, Saif ; Somvanshi, Pallavi
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:BioMed research international, 2015-01, Vol.2015 (2015), p.1-9
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Biological evaluation of both enantiomers of fluoro-thalidomide using human myeloma cell line H929 and others
Author / Creator:Tokunaga, Etsuko ; Akiyama, Hidehiko ; Soloshonok, Vadim A. ; Inoue, Yuki ; Hara, Hideaki ; Shibata, Norio
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-08, Vol.12 (8), p.e0182152
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Ru(II)-Thymine Complex Causes Cell Growth Inhibition and Induction of Caspase-Mediated Apoptosis in Human Promyelocytic Leukemia HL-60 Cells
Author / Creator:De Souza Oliveira, Maiara ; De Santana, Ádila Angélica Dantas ; Correa, Rodrigo S. ; Soares, Milena Botelho Pereira ; Batista, Alzir Azevedo ; Bezerra, Daniel Pereira
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2018-05, Vol.19 (6), p.1609
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Efficient synthesis, biological evaluation, and docking study of isatin based derivatives as caspase inhibitors
Author / Creator:Firoozpour, Loghman ; Gao, Lixin ; Moghimi, Setareh ; Pasalar, Parvin ; Davoodi, Jamshid ; Wang, Ming-Wei ; Rezaei, Zahra ; Dadgar, Armin ; Yahyavi, Hoda ; Amanlou, Massoud ; Foroumadi, Alireza
Publisher:England: Taylor & Francis
Journal title:Journal of enzyme inhibition and medicinal chemistry, 2020-01, Vol.35 (1), p.1674-1684
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Identification of Allosteric Inhibitors against Active Caspase-6
Author / Creator:Tubeleviciute-Aydin, Agne ; Beautrait, Alexandre ; Lynham, Jeffrey ; Sharma, Gyanesh ; Gorelik, Alexei ; Deny, Ludovic J. ; Soya, Naoto ; Lukacs, Gergely L. ; Nagar, Bhushan ; Marinier, Anne ; LeBlanc, Andrea C.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-04, Vol.9 (1), p.5504, Article 5504
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In Silico Drug Repurposing for Anti-Inflammatory Therapy: Virtual Search for Dual Inhibitors of Caspase-1 and TNF-Alpha
Author / Creator:Speck-Planche, Alejandro ; Kleandrova, Valeria V. ; Scotti, Marcus T.
Publisher:Switzerland: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2021-12, Vol.11 (12), p.1832
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Matrix Metalloproteinase Triple-Helical Peptide Inhibitors: Potential Cross-Reactivity with Caspase-11
Author / Creator:Knapinska, Anna M. ; Hart, Melissa ; Drotleff, Gary ; Fields, Gregg B.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2019-11, Vol.24 (23), p.4355
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Effects of the selective inhibition of proteasome caspase-like activity by CLi a derivative of nor-cerpegin in dystrophic mdx mice
Author / Creator:Hovhannisyan, Yeranuhi ; Melikyan, Gagik ; Mougenot, Nathalie ; Gao-Li, Jacqueline ; Friguet, Bertrand ; Paulin, Denise ; Li, Zhenlin ; Ferry, Arnaud ; Agbulut, Onnik
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-04, Vol.14 (4), p.e0215821-e0215821
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Cancer-selective, single agent chemoradiosensitising gold nanoparticles
Author / Creator:Grellet, Sophie ; Tzelepi, Konstantina ; Roskamp, Meike ; Williams, Phil ; Sharif, Aquila ; Slade-Carter, Richard ; Goldie, Peter ; Whilde, Nicky ; Śmiałek, Małgorzata A. ; Mason, Nigel J. ; Golding, Jon P.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-07, Vol.12 (7), p.e0181103
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Showing 1 to 20 of 29 results

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Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor

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Study of Caspase 8 Inhibition for the Management of Alzheimer’s Disease: A Molecular Docking and Dynamics Simulation

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The Selective 3-MST Inhibitor I3MT-3 Works as a Potent Caspase-1 Inhibitor

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Caspase selective reagents for diagnosing apoptotic mechanisms

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Gasdermin E-derived caspase-3 inhibitors effectively protect mice from acute hepatic failure

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Specific covalent inhibition of MALT1 paracaspase suppresses B cell lymphoma growth

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Synthesis, Characterization, and In Vivo Study of Some Novel 3,4,5-Trimethoxybenzylidene-hydrazinecarbothioamides and Thiadiazoles as Anti-Apoptotic Caspase-3 Inhibitors

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Design, Synthesis, Molecular Docking, Antiapoptotic and Caspase-3 Inhibition of New 1,2,3-Triazole/Bis-2(1H)-Quinolinone Hybrids

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A Fluorescence-Polarization-Based Lipopolysaccharide–Caspase-4 Interaction Assay for the Development of Inhibitors

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The E. coli Effector Protein NleF Is a Caspase Inhibitor

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Mechanism of Caspase-1 Inhibition by Four Anti-inflammatory Drugs Used in COVID-19 Treatment

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Implication of Caspase-3 as a Common Therapeutic Target for Multineurodegenerative Disorders and Its Inhibition Using Nonpeptidyl Natural Compounds

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Biological evaluation of both enantiomers of fluoro-thalidomide using human myeloma cell line H929 and others

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Ru(II)-Thymine Complex Causes Cell Growth Inhibition and Induction of Caspase-Mediated Apoptosis in Human Promyelocytic Leukemia HL-60 Cells

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Efficient synthesis, biological evaluation, and docking study of isatin based derivatives as caspase inhibitors

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Identification of Allosteric Inhibitors against Active Caspase-6

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In Silico Drug Repurposing for Anti-Inflammatory Therapy: Virtual Search for Dual Inhibitors of Caspase-1 and TNF-Alpha

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Matrix Metalloproteinase Triple-Helical Peptide Inhibitors: Potential Cross-Reactivity with Caspase-11

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Effects of the selective inhibition of proteasome caspase-like activity by CLi a derivative of nor-cerpegin in dystrophic mdx mice

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Cancer-selective, single agent chemoradiosensitising gold nanoparticles

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