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Chalcone Derivatives: Promising Starting Points for Drug Design
Author / Creator:Gomes, Marcelo ; Muratov, Eugene ; Pereira, Maristela ; Peixoto, Josana ; Rosseto, Lucimar ; Cravo, Pedro ; Andrade, Carolina ; Neves, Bruno
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2017-07, Vol.22 (8), p.1210
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Chalcone Scaffolds, Bioprecursors of Flavonoids: Chemistry, Bioactivities, and Pharmacokinetics
Author / Creator:Rudrapal, Mithun ; Khan, Johra ; Dukhyil, Abdul Aziz Bin ; Alarousy, Randa Mohammed Ibrahim Ismail ; Attah, Emmanuel Ifeanyi ; Sharma, Tripti ; Khairnar, Shubham Jagdish ; Bendale, Atul Rupchand
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2021-11, Vol.26 (23), p.7177
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Anticancer Activity of Natural and Synthetic Chalcones
Author / Creator:Constantinescu, Teodora ; Lungu, Claudiu N.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2021-10, Vol.22 (21), p.11306
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Novel coumarin-6-sulfonamide-chalcone hybrids as glutathione transferase P1-1 inhibitors
Author / Creator:Sabt, Ahmed ; Kitsos, Stefanos ; Ebaid, Manal S. ; Furlan, Veronika ; Pantiora, Panagiota D. ; Tsolka, Magdalini ; Elkaeed, Eslam B. ; Hamissa, Mohamed Farouk ; Angelis, Nikolaos ; Tsitsilonis, Ourania E. ; Papageorgiou, Anastassios C. ; Bren, Urban ; Labrou, Nikolaos E.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2024-08, Vol.19 (8), p.e0306124
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Fragment optimized chalcone derivatives targeting OmpA protein as a therapeutic approach against multidrug resistant Acinetobacter baumannii
Author / Creator:Naveed, Muhammad ; Abid, Amina ; Aziz, Tariq ; Saleem, Ayesha ; Arshad, Arooj ; Javed, Khushbakht ; Rehman, Hafiz Muzzammel ; Nabi, Ghulam ; Al-harbi, Mitub ; Alasmari, Abdullah F.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-01, Vol.15 (1), p.3917-19, Article 3917
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1, 4-benzodioxan-substituted Thienyl chalcone derivatives as novel reversible inhibitors of human monoamine oxidase B with anti-neuroinflammatory activity
Author / Creator:Sun, Demeng ; Mu, Mengxue ; Jiang, Yanmei ; Wang, Bo ; Kong, Zuo ; Tan, Jingbo ; Hu, Yun
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-03, Vol.15 (1), p.8690-13, Article 8690
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Synthesis and Anticancer Evaluation of O-Alkylated (E)-Chalcone Derivatives: A Focus on Estrogen Receptor Inhibition
Author / Creator:Al-Ghamdi, Alwah R. ; Ahmed, Wahid U. ; Al-Wabli, Reem I. ; Al-Mutairi, Maha S. ; Rahman, A. F. M. Motiur
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2025-01, Vol.26 (2), p.833
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Synthesis, antifungal activity and mechanism of action of novel chalcone derivatives containing 1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazole
Author / Creator:Zhan, Wenliang ; Zhou, Ran ; Mao, Piao ; Yuan, Chunmei ; Zhang, Tao ; Liu, Yi ; Tian, Jiao ; Wang, Hua ; Xue, Wei
Publisher:Cham: Springer International Publishing
Journal title:Molecular diversity, 2024-04, Vol.28 (2), p.461-474
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Modulatory Effects of Chalcone Thio-Derivatives on NF-κB and STAT3 Signaling Pathways in Hepatocellular Carcinoma Cells: A Study on Selected Active Compounds
Author / Creator:Papierska, Katarzyna ; Judasz, Eliza ; Tonińska, Wiktoria ; Kubicki, Maciej ; Krajka-Kuźniak, Violetta
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2024-10, Vol.25 (19), p.10739
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Recent Advances in Bioactive Flavonoid Hybrids Linked by 1,2,3-Triazole Ring Obtained by Click Chemistry
Author / Creator:Pereira, Daniela ; Pinto, Madalena ; Correia-da-Silva, Marta ; Cidade, Honorina
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2021-12, Vol.27 (1), p.230
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Novel Class of Chalcone Oxime Ethers as Potent Monoamine Oxidase-B and Acetylcholinesterase Inhibitors
Author / Creator:Oh, Jong Min ; Rangarajan, T. M. ; Chaudhary, Reeta ; Singh, Rishi Pal ; Singh, Manjula ; Singh, Raj Pal ; Tondo, Anna Rita ; Gambacorta, Nicola ; Nicolotti, Orazio ; Mathew, Bijo ; Kim, Hoon
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2020-05, Vol.25 (10), p.2356
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A Novel Tetramethylpyrazine Chalcone Hybrid- HCTMPPK, as a Potential Anti-Lung Cancer Agent by Downregulating MELK
Author / Creator:Ma, Yan ; Cui, Qian ; Zhu, Wenjing ; Wang, Mei ; Zhai, Li ; Hu, Wenmin ; Liu, Dongdong ; Liu, Min ; Li, Yongchun ; Li, Meng ; Han, Wei
Publisher:New Zealand: Dove Medical Press Limited
Journal title:Drug design, development and therapy, 2024-01, Vol.18, p.1531-1546
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Design, Synthesis and Anti-Tumor Activity of Novel Benzimidazole-Chalcone Hybrids as Non-Intercalative Topoisomerase II Catalytic Inhibitors
Author / Creator:Zhou, Wei ; Zhang, Wenjin ; Peng, Yi ; Jiang, Zhi-Hong ; Zhang, Lanyue ; Du, Zhiyun
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2020-07, Vol.25 (14), p.3180
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Targeting myeloid differentiation protein 2 by the new chalcone L2H21 protects LPS‐induced acute lung injury
Author / Creator:Zhang, Yali ; Xu, Tingting ; Wu, Beibei ; Chen, Hongjin ; Pan, Zheer ; Huang, Yi ; Mei, Liqin ; Dai, Yuanrong ; Liu, Xing ; Shan, Xiaoou ; Liang, Guang
Publisher:England: John Wiley & Sons, Inc
Journal title:Journal of cellular and molecular medicine, 2017-04, Vol.21 (4), p.746-757
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Semi-Synthesis of Different Pyranoflavonoid Backbones and the Neurogenic Potential
Author / Creator:Urmann, Corinna ; Bieler, Lara ; Hackl, Michael ; Chia-Leeson, Olivia ; Couillard-Despres, Sebastien ; Riepl, Herbert
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2023-05, Vol.28 (10), p.4023
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Tetramethoxychalcone, a Chalcone Derivative, Suppresses Proliferation, Blocks Cell Cycle Progression, and Induces Apoptosis of Human Ovarian Cancer Cells
Author / Creator:Qi, Zihao ; Liu, Mingming ; Liu, Yang ; Zhang, Meiqin ; Yang, Gong
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-09, Vol.9 (9), p.e106206
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ID2 and GJB2 promote early-stage breast cancer progression by regulating cancer stemness
Author / Creator:Liu, Yin ; Pandey, Puspa R. ; Sharma, Sambad ; Xing, Fei ; Wu, Kerui ; Chittiboyina, Amar ; Wu, Shih-Ying ; Tyagi, Abhishek ; Watabe, Kounosuke
Publisher:New York: Springer US
Journal title:Breast cancer research and treatment, 2019-05, Vol.175 (1), p.77-90
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Characterization of a Natural, Stable, Reversible and Colourful Anthocyanidin Network from Sphagnum Moss Based Mainly on the Yellow Trans-Chalcone and Red Flavylium Cation Forms
Author / Creator:Berland, Helge ; Andersen, Øyvind M.
Publisher:Switzerland: MDPI
Journal title:Molecules (Basel, Switzerland), 2021-01, Vol.26 (3), p.709
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LAP5 and LAP6 Encode Anther-Specific Proteins with Similarity to Chalcone Synthase Essential for Pollen Exine Development in Arabidopsis
Author / Creator:Dobritsa, Anna A ; Lei, Zhentian ; Nishikawa, Shuh-ichi ; Urbanczyk-Wochniak, Ewa ; Huhman, David V ; Preuss, Daphne ; Sumner, Lloyd W
Publisher:Rockville, MD: American Society of Plant Biologists
Journal title:Plant physiology (Bethesda), 2010-07, Vol.153 (3), p.937-955
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Design, synthesis, and evaluation of chalcone-Vitamin E-donepezil hybrids as multi-target-directed ligands for the treatment of Alzheimer's disease
Author / Creator:Sang, Zhipei ; Song, Qing ; Cao, Zhongcheng ; Deng, Yong ; Zhang, Li
Publisher:England: Taylor & Francis
Journal title:Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.69-85
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Showing 1 to 20 of 381 results

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Chalcone Derivatives: Promising Starting Points for Drug Design

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Chalcone Scaffolds, Bioprecursors of Flavonoids: Chemistry, Bioactivities, and Pharmacokinetics

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Anticancer Activity of Natural and Synthetic Chalcones

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Novel coumarin-6-sulfonamide-chalcone hybrids as glutathione transferase P1-1 inhibitors

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Fragment optimized chalcone derivatives targeting OmpA protein as a therapeutic approach against multidrug resistant Acinetobacter baumannii

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1, 4-benzodioxan-substituted Thienyl chalcone derivatives as novel reversible inhibitors of human monoamine oxidase B with anti-neuroinflammatory activity

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Synthesis and Anticancer Evaluation of O-Alkylated (E)-Chalcone Derivatives: A Focus on Estrogen Receptor Inhibition

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Synthesis, antifungal activity and mechanism of action of novel chalcone derivatives containing 1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazole

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Modulatory Effects of Chalcone Thio-Derivatives on NF-κB and STAT3 Signaling Pathways in Hepatocellular Carcinoma Cells: A Study on Selected Active Compounds

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Recent Advances in Bioactive Flavonoid Hybrids Linked by 1,2,3-Triazole Ring Obtained by Click Chemistry

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Novel Class of Chalcone Oxime Ethers as Potent Monoamine Oxidase-B and Acetylcholinesterase Inhibitors

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A Novel Tetramethylpyrazine Chalcone Hybrid- HCTMPPK, as a Potential Anti-Lung Cancer Agent by Downregulating MELK

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Design, Synthesis and Anti-Tumor Activity of Novel Benzimidazole-Chalcone Hybrids as Non-Intercalative Topoisomerase II Catalytic Inhibitors

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Targeting myeloid differentiation protein 2 by the new chalcone L2H21 protects LPS‐induced acute lung injury

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Semi-Synthesis of Different Pyranoflavonoid Backbones and the Neurogenic Potential

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Tetramethoxychalcone, a Chalcone Derivative, Suppresses Proliferation, Blocks Cell Cycle Progression, and Induces Apoptosis of Human Ovarian Cancer Cells

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ID2 and GJB2 promote early-stage breast cancer progression by regulating cancer stemness

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Characterization of a Natural, Stable, Reversible and Colourful Anthocyanidin Network from Sphagnum Moss Based Mainly on the Yellow Trans-Chalcone and Red Flavylium Cation Forms

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LAP5 and LAP6 Encode Anther-Specific Proteins with Similarity to Chalcone Synthase Essential for Pollen Exine Development in Arabidopsis

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Design, synthesis, and evaluation of chalcone-Vitamin E-donepezil hybrids as multi-target-directed ligands for the treatment of Alzheimer's disease

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