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ArticlesPeer ReviewedFull Text
RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself
Author / Creator:Liddicoat, Brian J. ; Piskol, Robert ; Chalk, Alistair M. ; Ramaswami, Gokul ; Higuchi, Miyoko ; Hartner, Jochen C. ; Li, Jin Billy ; Seeburg, Peter H. ; Walkley, Carl R.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2015-09, Vol.349 (6252), p.1115-1120
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ArticlesPeer ReviewedFull Text
The majority of A-to-I RNA editing is not required for mammalian homeostasis
Author / Creator:Chalk, Alistair M. ; Taylor, Scott ; Heraud-Farlow, Jacki E. ; Walkley, Carl R.
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology, 2019-12, Vol.20 (1), p.268-268, Article 268
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ArticlesPeer ReviewedFull Text
Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis
Author / Creator:Heraud-Farlow, Jacki E. ; Chalk, Alistair M. ; Linder, Sandra E. ; Li, Qin ; Taylor, Scott ; White, Joshua M. ; Pang, Lokman ; Liddicoat, Brian J. ; Gupte, Ankita ; Li, Jin Billy ; Walkley, Carl R.
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology, 2017-09, Vol.18 (1), p.166-166, Article 166
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ArticlesPeer ReviewedFull Text
Hematopoietic stem and progenitor cell-restricted Cdx2 expression induces transformation to myelodysplasia and acute leukemia
Author / Creator:Vu, Therese ; Straube, Jasmin ; Porter, Amy H. ; Bywater, Megan ; Song, Axia ; Ling, Victoria ; Cooper, Leanne ; Pali, Gabor ; Bruedigam, Claudia ; Jacquelin, Sebastien ; Green, Joanne ; Magor, Graham ; Perkins, Andrew ; Chalk, Alistair M. ; Walkley, Carl R. ; Heidel, Florian H. ; Mukhopadhyay, Pamela ; Cloonan, Nicole ; Gröschel, Stefan ; Mallm, Jan-Philipp ; Fröhling, Stefan ; Scholl, Claudia ; Lane, Steven W.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-06, Vol.11 (1), p.3021-15, Article 3021
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ArticlesPeer ReviewedFull Text
The Rothmund-Thomson syndrome helicase RECQL4 is essential for hematopoiesis
Author / Creator:Smeets, Monique F. ; DeLuca, Elisabetta ; Wall, Meaghan ; Quach, Julie M. ; Chalk, Alistair M. ; Deans, Andrew J. ; Heierhorst, Jörg ; Purton, Louise E. ; Izon, David J. ; Walkley, Carl R.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2014-08, Vol.124 (8), p.3551-3565
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ArticlesPeer ReviewedFull Text
Disease-specific, neurosphere-derived cells as models for brain disorders
Author / Creator:Matigian, Nicholas ; Abrahamsen, Greger ; Sutharsan, Ratneswary ; Cook, Anthony L. ; Vitale, Alejandra M. ; Nouwens, Amanda ; Bellette, Bernadette ; An, Jiyuan ; Anderson, Matthew ; Beckhouse, Anthony G. ; Bennebroek, Maikel ; Cecil, Rowena ; Chalk, Alistair M. ; Cochrane, Julie ; Fan, Yongjun ; Féron, François ; McCurdy, Richard ; McGrath, John J. ; Murrell, Wayne ; Perry, Chris ; Raju, Jyothy ; Ravishankar, Sugandha ; Silburn, Peter A. ; Sutherland, Greg T. ; Mahler, Stephen ; Mellick, George D. ; Wood, Stephen A. ; Sue, Carolyn M. ; Wells, Christine A. ; Mackay-Sim, Alan
Publisher:England: The Company of Biologists Ltd
Journal title:Disease models & mechanisms, 2010-11, Vol.3 (11-12), p.785-798
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ArticlesPeer ReviewedFull Text
Activation of PTHrP-cAMP-CREB1 signaling following p53 loss is essential for osteosarcoma initiation and maintenance
Author / Creator:Walia, Mannu K ; Ho, Patricia MW ; Taylor, Scott ; Ng, Alvin JM ; Gupte, Ankita ; Chalk, Alistair M ; Zannettino, Andrew CW ; Martin, T John ; Walkley, Carl R
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2016-04, Vol.5
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ArticlesPeer ReviewedFull Text
A Cross-Study Transcriptional Analysis of Parkinson's Disease
Author / Creator:Sutherland, Greg T. ; Matigian, Nicholas A. ; Chalk, Alistair M. ; Anderson, Matthew J. ; Silburn, Peter A. ; Mackay-Sim, Alan ; Wells, Christine A. ; Mellick, George D.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2009-03, Vol.4 (3), p.e4955
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ArticlesPeer ReviewedFull Text
RNAi Screen Indicates Widespread Biological Function for Human Natural Antisense Transcripts
Author / Creator:Faghihi, Mohammad Ali ; Kocerha, Jannet ; Modarresi, Farzaneh ; Engström, Pär G. ; Chalk, Alistair M. ; Brothers, Shaun P. ; Koesema, Eric ; St. Laurent, Georges ; Wahlestedt, Claes
Publisher:United States: Public Library of Science
Journal title:PloS one, 2010-10, Vol.5 (10), p.e13177
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ArticlesPeer ReviewedFull Text
Alternate transcription of the Toll-like receptor signaling cascade
Author / Creator:Wells, Christine A ; Chalk, Alistair M ; Forrest, Alistair ; Taylor, Darrin ; Waddell, Nic ; Schroder, Kate ; Himes, S Roy ; Faulkner, Geoffrey ; Lo, Sandra ; Kasukawa, Takeya ; Kawaji, Hideya ; Kai, Chikatoshi ; Kawai, Jun ; Katayama, Shintaro ; Carninci, Piero ; Hayashizaki, Yoshihide ; Hume, David A ; Grimmond, Sean M
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology (Online Edition), 2006-02, Vol.7 (2), p.R10-1278, Article R10
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ArticlesPeer ReviewedFull Text
Srsf2P95H/+ co-operates with loss of TET2 to promote myeloid bias and initiate a chronic myelomonocytic leukemia-like disease in mice
Author / Creator:Xu, Jane Jialu ; Chalk, Alistair M. ; Wall, Meaghan ; Langdon, Wallace Y. ; Smeets, Monique F. ; Walkley, Carl R.
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2022-12, Vol.36 (12), p.2883-2893
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ArticlesPeer ReviewedFull Text
BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cells
Author / Creator:Baker, Emma K ; Taylor, Scott ; Gupte, Ankita ; Sharp, Phillip P ; Walia, Mannu ; Walsh, Nicole C ; Zannettino, Andrew CW ; Chalk, Alistair M ; Burns, Christopher J ; Walkley, Carl R
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2015-05, Vol.5 (1), p.10120-10120, Article 10120
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ArticlesPeer ReviewedFull Text
Genome-wide review of transcriptional complexity in mouse protein kinases and phosphatases
Author / Creator:Forrest, Alistair RR ; Taylor, Darrin F ; Crowe, Mark L ; Chalk, Alistair M ; Waddell, Nic J ; Kolle, Gabriel ; Faulkner, Geoffrey J ; Kodzius, Rimantas ; Katayama, Shintaro ; Wells, Christine ; Kai, Chikatoshi ; Kawai, Jun ; Carninci, Piero ; Hayashizaki, Yoshihide ; Grimmond, Sean M
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology (Online Edition), 2006-01, Vol.7 (1), p.R5-1273, Article R5
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ArticlesPeer ReviewedFull Text
Profiled support vector machines for antisense oligonucleotide efficacy prediction
Author / Creator:Camps-Valls, Gustavo ; Chalk, Alistair M ; Serrano-López, Antonio J ; Martín-Guerrero, José D ; Sonnhammer, Erik LL
Publisher:England: BioMed Central Ltd
Journal title:BMC bioinformatics, 2004-09, Vol.5 (1), p.135-135, Article 135
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ArticlesPeer ReviewedFull Text
Srsf2 P95H/+ co-operates with loss of TET2 to promote myeloid bias and initiate a chronic myelomonocytic leukemia-like disease in mice
Author / Creator:Xu, Jane Jialu ; Chalk, Alistair M ; Wall, Meaghan ; Langdon, Wallace Y ; Smeets, Monique F ; Walkley, Carl R
Publisher:England
Journal title:Leukemia, 2022-12, Vol.36 (12), p.2883
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RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself

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The majority of A-to-I RNA editing is not required for mammalian homeostasis

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Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis

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Hematopoietic stem and progenitor cell-restricted Cdx2 expression induces transformation to myelodysplasia and acute leukemia

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The Rothmund-Thomson syndrome helicase RECQL4 is essential for hematopoiesis

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Disease-specific, neurosphere-derived cells as models for brain disorders

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Activation of PTHrP-cAMP-CREB1 signaling following p53 loss is essential for osteosarcoma initiation and maintenance

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A Cross-Study Transcriptional Analysis of Parkinson's Disease

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RNAi Screen Indicates Widespread Biological Function for Human Natural Antisense Transcripts

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Alternate transcription of the Toll-like receptor signaling cascade

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Srsf2P95H/+ co-operates with loss of TET2 to promote myeloid bias and initiate a chronic myelomonocytic leukemia-like disease in mice

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BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cells

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Genome-wide review of transcriptional complexity in mouse protein kinases and phosphatases

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Profiled support vector machines for antisense oligonucleotide efficacy prediction

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Srsf2 P95H/+ co-operates with loss of TET2 to promote myeloid bias and initiate a chronic myelomonocytic leukemia-like disease in mice

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