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29 results for Choi,+Uimook

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Correction of X-CGD patient HSPCs by targeted CYBB cDNA insertion using CRISPR/Cas9 with 53BP1 inhibition for enhanced homology-directed repair
Author / Creator:Sweeney, Colin L. ; Pavel-Dinu, Mara ; Choi, Uimook ; Brault, Julie ; Liu, Taylor ; Koontz, Sherry ; Li, Linhong ; Theobald, Narda ; Lee, Janet ; Bello, Ezekiel A. ; Wu, Xiaolin ; Meis, Ronald J. ; Dahl, Gary A. ; Porteus, Matthew H. ; Malech, Harry L. ; De Ravin, Suk See
Publisher:London: Nature Publishing Group UK
Journal title:Gene therapy, 2021-06, Vol.28 (6), p.373-390
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Lentivector cryptic splicing mediates increase in CD34+ clones expressing truncated HMGA2 in human X-linked severe combined immunodeficiency
Author / Creator:De Ravin, Suk See ; Liu, Siyuan ; Sweeney, Colin L. ; Brault, Julie ; Whiting-Theobald, Narda ; Ma, Michelle ; Liu, Taylor ; Choi, Uimook ; Lee, Janet ; O’Brien, Sandra Anaya ; Quackenbush, Priscilla ; Estwick, Tyra ; Karra, Anita ; Docking, Ethan ; Kwatemaa, Nana ; Guo, Shuang ; Su, Ling ; Sun, Zhonghe ; Zhou, Sheng ; Puck, Jennifer ; Cowan, Morton J. ; Notarangelo, Luigi D. ; Kang, Elizabeth ; Malech, Harry L. ; Wu, Xiaolin
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-06, Vol.13 (1), p.3710-3710, Article 3710
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The regulatory role of ACP5 in the diesel exhaust particle-induced AHR inflammatory signaling pathway in a human bronchial epithelial cell line
Author / Creator:Yu, Aaron ; Yoon, Dankyu ; An, Hye Bin ; Choi, Uimook ; Heo, Hye-Ryeon ; Chae, Dong-Hoon ; Park, Hyun Sung ; Park, Jae Han ; Han, Myoung Hee ; Heo, Jiyoung ; Cho, Keonwoo ; Park, Ki-Sun ; Yoo, Hee Min ; Kim, Hyung-Sik ; Kang, Kyung-Sun ; Oh, Mi-Kyung ; Lim, Hyun Joung ; Yu, Kyung-Rok
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-03, Vol.15 (1), p.8826-12, Article 8826
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Extracellular Vesicles from Thapsigargin-Treated Mesenchymal Stem Cells Ameliorated Experimental Colitis via Enhanced Immunomodulatory Properties
Author / Creator:Joo, Hansol ; Oh, Mi-Kyung ; Kang, Ji Yeon ; Park, Hyun Sung ; Chae, Dong-Hoon ; Kim, Jieun ; Lee, Jong-Hee ; Yoo, Hee Min ; Choi, Uimook ; Kim, Do-Kyun ; Lee, Hakmo ; Kim, Sungjoo ; Yu, Kyung-Rok
Publisher:Switzerland: MDPI
Journal title:Biomedicines, 2021-02, Vol.9 (2), p.209
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Lentiviral gene therapy for X-linked chronic granulomatous disease
Author / Creator:Kohn, Donald B. ; Booth, Claire ; Kang, Elizabeth M. ; Pai, Sung-Yun ; Shaw, Kit L. ; Santilli, Giorgia ; Armant, Myriam ; Buckland, Karen F. ; Choi, Uimook ; De Ravin, Suk See ; Dorsey, Morna J. ; Kuo, Caroline Y. ; Leon-Rico, Diego ; Rivat, Christine ; Izotova, Natalia ; Gilmour, Kimberly ; Snell, Katie ; Dip, Jinhua Xu-Bayford ; Darwish, Jinan ; Morris, Emma C. ; Terrazas, Dayna ; Wang, Leo D. ; Bauser, Christopher A. ; Paprotka, Tobias ; Kuhns, Douglas B. ; Gregg, John ; Raymond, Hayley E. ; Everett, John K. ; Honnet, Geraldine ; Biasco, Luca ; Newburger, Peter E. ; Bushman, Frederic D. ; Grez, Manuel ; Gaspar, H. Bobby ; Williams, David A. ; Malech, Harry L. ; Galy, Anne ; Thrasher, Adrian J.
Publisher:New York: Nature Publishing Group US
Journal title:Nature Medicine, 2020-02, Vol.26 (2), p.200-206
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Targeted gene addition in human CD34+ hematopoietic cells for correction of X-linked chronic granulomatous disease
Author / Creator:De Ravin, Suk See ; Reik, Andreas ; Liu, Pei-Qi ; Li, Linhong ; Wu, Xiaolin ; Su, Ling ; Raley, Castle ; Theobald, Narda ; Choi, Uimook ; Song, Alexander H ; Chan, Andy ; Pearl, Jocelynn R ; Paschon, David E ; Lee, Janet ; Newcombe, Hannah ; Koontz, Sherry ; Sweeney, Colin ; Shivak, David A ; Zarember, Kol A ; Peshwa, Madhusudan V ; Gregory, Philip D ; Urnov, Fyodor D ; Malech, Harry L
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2016-04, Vol.34 (4), p.424-429
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Targeted Repair of CYBB in X-CGD iPSCs Requires Retention of Intronic Sequences for Expression and Functional Correction
Author / Creator:Sweeney, Colin L. ; Zou, Jizhong ; Choi, Uimook ; Merling, Randall K. ; Liu, Alexander ; Bodansky, Aaron ; Burkett, Sandra ; Kim, Jung-Woong ; De Ravin, Suk See ; Malech, Harry L.
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2017-02, Vol.25 (2), p.321-330
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Biochemical Correction of X-CGD by a Novel Chimeric Promoter Regulating High Levels of Transgene Expression in Myeloid Cells
Author / Creator:Santilli, Giorgia ; Almarza, Elena ; Brendel, Christian ; Choi, Uimook ; Beilin, Chiara ; Blundell, Michael P ; Haria, Sneha ; Parsley, Kathryn L ; Kinnon, Christine ; Malech, Harry L ; Bueren, Juan A ; Grez, Manuel ; Thrasher, Adrian J
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2011-01, Vol.19 (1), p.122-132
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An AAVS1-Targeted Minigene Platform for Correction of iPSCs From All Five Types of Chronic Granulomatous Disease
Author / Creator:Merling, Randall K ; Sweeney, Colin L ; Chu, Jessica ; Bodansky, Aaron ; Choi, Uimook ; Priel, Debra Long ; Kuhns, Douglas B ; Wang, Hongmei ; Vasilevsky, Sam ; De Ravin, Suk See ; Winkler, Thomas ; Dunbar, Cynthia E ; Zou, Jizhong ; Zarember, Kol A ; Gallin, John I ; Holland, Steven M ; Malech, Harry L
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2015-01, Vol.23 (1), p.147-157
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A Novel Method for Screening Adenosine Receptor Specific Agonists for Use in Adenosine Drug Development
Author / Creator:Jones, Karlie R. ; Choi, Uimook ; Gao, Ji-Liang ; Thompson, Robert D. ; Rodman, Larry E. ; Malech, Harry L. ; Kang, Elizabeth M.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-03, Vol.7 (1), p.44816-44816, Article 44816
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57. Seamless Targeted Correction of CYBB Exon 5 Mutations Restores Granulocyte Function in X-Linked Chronic Granulomatous Disease iPSCs
Author / Creator:Sweeney, Colin L. ; Zou, Jizhong ; Choi, Uimook ; Merling, Randall K. ; See DeRavin, Suk ; Malech, Harry L.
Publisher:Elsevier Inc
Journal title:Molecular therapy, 2015-05, Vol.23, p.S25-S25
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557. Targeted CYBB Minigene Insertion into the CYBB Locus for Correction of X-CGD iPSCs Requires Intronic Elements for Expression
Author / Creator:Sweeney, Colin L. ; Choi, Uimook ; Zou, Jizhong ; Merling, Randall K. ; Ravin, Suk See De ; Malech, Harry L.
Publisher:Elsevier Inc
Journal title:Molecular therapy, 2016-05, Vol.24, p.S223-S223
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298. Transfection of Neutrophils from X-Linked Chronic Granulomatous Disease Patients with gp91phox mRNA Restores Oxidase Activity with High Efficiency and Viability
Author / Creator:See De Ravin, Suk ; Li, Linhong ; Choi, Uimook ; Chu, Jessica ; Theobald, Narda ; Koontz, Sherry ; Lee, Janet ; Zarember, Kol ; Khuu, Hanh ; Cantilena, Cathy ; Peshwa, Madhusudan V. ; Malech, Harry L.
Publisher:Elsevier Inc
Journal title:Molecular therapy, 2015-05, Vol.23, p.S120-S121
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41. Therapeutic Level CRISPR-Oligomer-Mediated Correction of X-CGD Patient Hematopoietic Stem Cells Using Non-Viral, cGMP Compliant, Scalable, and Closed System
Author / Creator:Li, Linhong ; see De Ravin, Suk ; Allen, Cornell ; Choi, Uimook ; Koontz, Sherry ; Theobald, Narda ; Lee, Janet ; Viley, Angelia ; Natarajan, Pachai ; NewCombe, Hannah ; McMichael, Ashley ; Wu, Xiaolin ; Malech, Harry L. ; Peshwa, Madhusudan V.
Publisher:Elsevier Inc
Journal title:Molecular therapy, 2016-05, Vol.24, p.S18-S18
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In vivo selection of hematopoietic progenitor cells and temozolomide dose intensification in rhesus macaques through lentiviral transduction with a drug resistance gene
Author / Creator:Larochelle, Andre ; Choi, Uimook ; Shou, Yan ; Naumann, Nora ; Loktionova, Natalia A ; Clevenger, Joshua R ; Krouse, Allen ; Metzger, Mark ; Donahue, Robert E ; Kang, Elizabeth ; Stewart, Clinton ; Persons, Derek ; Malech, Harry L ; Dunbar, Cynthia E ; Sorrentino, Brian P
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2009-07, Vol.119 (7), p.1952-1963
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Targeted gene addition in human CD34 super(+) hematopoietic cells for correction of X-linked chronic granulomatous disease
Author / Creator:De Ravin, Suk See ; Reik, Andreas ; Liu, Pei-Qi ; Li, Linhong ; Wu, Xiaolin ; Su, Ling ; Raley, Castle ; Theobald, Narda ; Choi, Uimook ; Song, Alexander H ; Chan, Andy ; Pearl, Jocelynn R ; Paschon, David E ; Lee, Janet ; Newcombe, Hannah ; Koontz, Sherry ; Sweeney, Colin ; Shivak, David A ; Zarember, Kol A ; Peshwa, Madhusudan V ; Gregory, Philip D ; Urnov, Fyodor D ; Malech, Harry L
Journal title:Nature biotechnology, 2016-04, Vol.34 (4), p.424-429
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Targeted gene addition in human hematopoietic cells for correction of X-linked chronic granulomatous disease
Author / Creator:De Ravin, Suk See ; Reik, Andreas ; Liu, Pei-Qi ; Li, Linhong ; Wu, Xiaolin ; Su, Ling ; Raley, Castle ; Theobald, Narda ; Choi, Uimook ; Song, Alexander H ; Chan, Andy ; Pearl, Jocelynn R ; Paschon, David E ; Lee, Janet ; Newcombe, Hannah ; Koontz, Sherry ; Sweeney, Colin ; Shivak, David A ; Zarember, Kol A ; Peshwa, Madhusudan V ; Gregory, Philip D ; Urnov, Fyodor D ; Malech, Harry L
Publisher:Nature Publishing Group
Journal title:Nature biotechnology, 2016-04, p.424
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Targeted Gene Addition to a Safe Harbor locus in human CD34+ Hematopoietic Stem Cells for Correction of X-linked Chronic Granulomatous Disease
Author / Creator:De Ravin, Suk See ; Reik, Andreas ; Liu, Pei-Qi ; Li, Linhong ; Wu, Xiaolin ; Su, Ling ; Raley, Castle ; Theobald, Narda ; Choi, Uimook ; Song, Alexander H. ; Chan, Andy ; Pearl, Jocelynn R. ; Paschon, David E. ; Lee, Janet ; Newcombe, Hannah ; Koontz, Sherry ; Sweeney, Colin ; Shivak, David A. ; Zarember, Kol A. ; Peshwa, Madhusudan V. ; Gregory, Philip D. ; Urnov, Fyodor D. ; Malech, Harry L.
Journal title:Nature biotechnology, 2016-03, Vol.34 (4), p.424-429
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54. Genome Editing of Primary Human CD34+ Hematopoietic Stem Cells Enables a Safe Harbor Targeted Gene Addition Therapeutic Strategy for Chronic Granulomatous Disease
Author / Creator:See De Ravin, Suk ; Reik, Andreas ; Liu, Pei-Qi ; Li, Linhong ; Peshwa, Madhusudan V. ; Theobald, Narda ; Choi, Uimook ; Lee, Janet ; Koontz, Sherry ; Lee, Gary ; Gregory, Philip D. ; Urnov, Fyodor D. ; Malech, Harry L.
Publisher:Elsevier Inc
Journal title:Molecular therapy, 2015-05, Vol.23, p.S24-S24
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Transgene-Free iPSCs Generated from Small Volume Peripheral Blood Non-mobilized CD34+ Cells
Author / Creator:Merling, Randall K ; Sweeney, Colin L ; Choi, Uimook ; DeRavin, Suk See ; Myers, Timothy G ; Otaizo-Carrasquero, Francisco ; Pan, Jason ; Linton, Gilda ; Chen, Lifeng ; Koontz, Sherry ; Theobald, Narda L ; Malech, Harry L
Journal title:Molecular therapy, 2012-09, Vol.20 (9), p.50-50
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Correction of X-CGD patient HSPCs by targeted CYBB cDNA insertion using CRISPR/Cas9 with 53BP1 inhibition for enhanced homology-directed repair

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Lentivector cryptic splicing mediates increase in CD34+ clones expressing truncated HMGA2 in human X-linked severe combined immunodeficiency

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The regulatory role of ACP5 in the diesel exhaust particle-induced AHR inflammatory signaling pathway in a human bronchial epithelial cell line

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Extracellular Vesicles from Thapsigargin-Treated Mesenchymal Stem Cells Ameliorated Experimental Colitis via Enhanced Immunomodulatory Properties

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Lentiviral gene therapy for X-linked chronic granulomatous disease

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Targeted gene addition in human CD34+ hematopoietic cells for correction of X-linked chronic granulomatous disease

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Targeted Repair of CYBB in X-CGD iPSCs Requires Retention of Intronic Sequences for Expression and Functional Correction

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Biochemical Correction of X-CGD by a Novel Chimeric Promoter Regulating High Levels of Transgene Expression in Myeloid Cells

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An AAVS1-Targeted Minigene Platform for Correction of iPSCs From All Five Types of Chronic Granulomatous Disease

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A Novel Method for Screening Adenosine Receptor Specific Agonists for Use in Adenosine Drug Development

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57. Seamless Targeted Correction of CYBB Exon 5 Mutations Restores Granulocyte Function in X-Linked Chronic Granulomatous Disease iPSCs

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557. Targeted CYBB Minigene Insertion into the CYBB Locus for Correction of X-CGD iPSCs Requires Intronic Elements for Expression

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298. Transfection of Neutrophils from X-Linked Chronic Granulomatous Disease Patients with gp91phox mRNA Restores Oxidase Activity with High Efficiency and Viability

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41. Therapeutic Level CRISPR-Oligomer-Mediated Correction of X-CGD Patient Hematopoietic Stem Cells Using Non-Viral, cGMP Compliant, Scalable, and Closed System

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In vivo selection of hematopoietic progenitor cells and temozolomide dose intensification in rhesus macaques through lentiviral transduction with a drug resistance gene

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Targeted gene addition in human CD34 super(+) hematopoietic cells for correction of X-linked chronic granulomatous disease

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Targeted gene addition in human hematopoietic cells for correction of X-linked chronic granulomatous disease

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Targeted Gene Addition to a Safe Harbor locus in human CD34+ Hematopoietic Stem Cells for Correction of X-linked Chronic Granulomatous Disease

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54. Genome Editing of Primary Human CD34+ Hematopoietic Stem Cells Enables a Safe Harbor Targeted Gene Addition Therapeutic Strategy for Chronic Granulomatous Disease

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Transgene-Free iPSCs Generated from Small Volume Peripheral Blood Non-mobilized CD34+ Cells

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