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ArticlesPeer ReviewedFull Text
The CRAPome: a contaminant repository for affinity purification–mass spectrometry data
Author / Creator:Mellacheruvu, Dattatreya ; Wright, Zachary ; Couzens, Amber L ; Lambert, Jean-Philippe ; St-Denis, Nicole A ; Li, Tuo ; Miteva, Yana V ; Hauri, Simon ; Sardiu, Mihaela E ; Low, Teck Yew ; Halim, Vincentius A ; Bagshaw, Richard D ; Hubner, Nina C ; al-Hakim, Abdallah ; Bouchard, Annie ; Faubert, Denis ; Fermin, Damian ; Dunham, Wade H ; Goudreault, Marilyn ; Lin, Zhen-Yuan ; Badillo, Beatriz Gonzalez ; Pawson, Tony ; Durocher, Daniel ; Coulombe, Benoit ; Aebersold, Ruedi ; Superti-Furga, Giulio ; Colinge, Jacques ; Heck, Albert J R ; Choi, Hyungwon ; Gstaiger, Matthias ; Mohammed, Shabaz ; Cristea, Ileana M ; Bennett, Keiryn L ; Washburn, Mike P ; Raught, Brian ; Ewing, Rob M ; Gingras, Anne-Claude ; Nesvizhskii, Alexey I
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2013-08, Vol.10 (8), p.730-736
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R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein
Author / Creator:Cloutier, Philippe ; Poitras, Christian ; Durand, Mathieu ; Hekmat, Omid ; Fiola-Masson, Émilie ; Bouchard, Annie ; Faubert, Denis ; Chabot, Benoit ; Coulombe, Benoit
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-05, Vol.8 (1), p.15615-15615, Article 15615
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ArticlesPeer ReviewedFull Text
A Newly Uncovered Group of Distantly Related Lysine Methyltransferases Preferentially Interact with Molecular Chaperones to Regulate Their Activity
Author / Creator:Cloutier, Philippe ; Lavallée-Adam, Mathieu ; Faubert, Denis ; Blanchette, Mathieu ; Coulombe, Benoit
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2013-01, Vol.9 (1), p.e1003210-e1003210
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ArticlesPeer ReviewedFull Text
Discovery of Antivirals Using Phage Display
Author / Creator:Sokullu, Esen ; Gauthier, Marie-Soleil ; Coulombe, Benoit
Publisher:Basel: MDPI AG
Journal title:Viruses, 2021-06, Vol.13 (6), p.1120
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ArticlesPeer ReviewedFull Text
ARMC5 controls the degradation of most Pol II subunits, and ARMC5 mutation increases neural tube defect risks in mice and humans
Author / Creator:Luo, Hongyu ; Lao, Linjiang ; Au, Kit Sing ; Northrup, Hope ; He, Xiao ; Forget, Diane ; Gauthier, Marie-Soleil ; Coulombe, Benoit ; Bourdeau, Isabelle ; Shi, Wei ; Gagliardi, Lucia ; Fragoso, Maria Candida Barisson Villares ; Peng, Junzheng ; Wu, Jiangping
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology, 2024-01, Vol.25 (1), p.19-19, Article 19
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ArticlesPeer ReviewedFull Text
Recessive mutations in POLR1C cause a leukodystrophy by impairing biogenesis of RNA polymerase III
Author / Creator:Thiffault, Isabelle ; Wolf, Nicole I. ; Forget, Diane ; Guerrero, Kether ; Tran, Luan T. ; Choquet, Karine ; Lavallée-Adam, Mathieu ; Poitras, Christian ; Brais, Bernard ; Yoon, Grace ; Sztriha, Laszlo ; Webster, Richard I. ; Timmann, Dagmar ; van de Warrenburg, Bart P. ; Seeger, Jürgen ; Zimmermann, Alíz ; Máté, Adrienn ; Goizet, Cyril ; Fung, Eva ; van der Knaap, Marjo S. ; Fribourg, Sébastien ; Vanderver, Adeline ; Simons, Cas ; Taft, Ryan J. ; Yates III, John R. ; Coulombe, Benoit ; Bernard, Geneviève
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-07, Vol.6 (1), p.7623-7623, Article 7623
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ArticlesPeer ReviewedFull Text
How do our cells build their protein interactome?
Author / Creator:Coulombe, Benoit ; Cloutier, Philippe ; Gauthier, Marie-Soleil
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-07, Vol.9 (1), p.2955-3, Article 2955
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ArticlesPeer ReviewedFull Text
The 37TrillionCells initiative for improving global healthcare via cell-based interception and precision medicine: focus on neurodegenerative diseases
Author / Creator:Coulombe, Benoit ; Durcan, Thomas M. ; Bernard, Geneviève ; Moursli, Asmae ; Poitras, Christian ; Faubert, Denis ; Pinard, Maxime
Publisher:England: BioMed Central Ltd
Journal title:Molecular brain, 2024-04, Vol.17 (1), p.18-18, Article 18
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Riluzole partially restores RNA polymerase III complex assembly in cells expressing the leukodystrophy-causative variant POLR3B R103H
Author / Creator:Pinard, Maxime ; Dastpeyman, Samaneh ; Poitras, Christian ; Bernard, Geneviève ; Gauthier, Marie-Soleil ; Coulombe, Benoit
Publisher:England: BioMed Central Ltd
Journal title:Molecular brain, 2022-11, Vol.15 (1), p.98-98, Article 98
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Newsletter articlesFull Text
WIPO PUBLISHES PATENT OF SCA HYGIENE PRODUCTS, COULOMBE BENOIT FOR "METHOD AND APPARATUS FOR TRIMMING MATERIAL FROM A WEB" (CANADIAN INVENTOR)
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2012
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ArticlesPeer ReviewedFull Text
Structural and functional characterization of the IgSF21-neurexin2α complex and its related signaling pathways in the regulation of inhibitory synapse organization
Author / Creator:Chofflet, Nicolas ; Naito, Yusuke ; Pastore, Anthony John ; Padmanabhan, Nirmala ; Nguyen, Phuong Trang ; Poitras, Christian ; Feller, Benjamin ; Yi, Nayoung ; Van Prooijen, Jeremie ; Khaled, Husam ; Coulombe, Benoit ; Clapcote, Steven J. ; Bourgault, Steve ; Siddiqui, Tabrez J. ; Rudenko, Gabby ; Takahashi, Hideto
Publisher:Switzerland: Frontiers Media S.A
Journal title:Frontiers in molecular neuroscience, 2024-03, Vol.17, p.1371145
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ArticlesPeer ReviewedFull Text
The leukodystrophy mutation Polr3b R103H causes homozygote mouse embryonic lethality and impairs RNA polymerase III biogenesis
Author / Creator:Choquet, Karine ; Pinard, Maxime ; Yang, Sharon ; Moir, Robyn D. ; Poitras, Christian ; Dicaire, Marie-Josée ; Sgarioto, Nicolas ; Larivière, Roxanne ; Kleinman, Claudia L. ; Willis, Ian M. ; Gauthier, Marie-Soleil ; Coulombe, Benoit ; Brais, Bernard
Publisher:England: BioMed Central Ltd
Journal title:Molecular brain, 2019-06, Vol.12 (1), p.59-59, Article 59
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ArticlesPeer ReviewedFull Text
Towards a Treatment for Leukodystrophy Using Cell-Based Interception and Precision Medicine
Author / Creator:Coulombe, Benoit ; Chapleau, Alexandra ; Macintosh, Julia ; Durcan, Thomas M. ; Poitras, Christian ; Moursli, Yena A. ; Faubert, Denis ; Pinard, Maxime ; Bernard, Geneviève
Publisher:Switzerland: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2024-07, Vol.14 (7), p.857
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ArticlesPeer ReviewedFull Text
Interactome Analysis of KIN (Kin17) Shows New Functions of This Protein
Author / Creator:Gaspar, Vanessa Pinatto ; Ramos, Anelise Cardoso ; Cloutier, Philippe ; Pattaro Junior, José Renato ; Duarte Junior, Francisco Ferreira ; Bouchard, Annie ; Seixas, Flavio Augusto Vicente ; Coulombe, Benoit ; Fernandez, Maria Aparecida
Publisher:MDPI
Journal title:Current issues in molecular biology, 2021-07, Vol.43 (2), p.767-781
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ArticlesPeer ReviewedFull Text
Absence of neurological abnormalities in mice homozygous for the Polr3a G672E hypomyelinating leukodystrophy mutation
Author / Creator:Choquet, Karine ; Yang, Sharon ; Moir, Robyn D. ; Forget, Diane ; Larivière, Roxanne ; Bouchard, Annie ; Poitras, Christian ; Sgarioto, Nicolas ; Dicaire, Marie-Josée ; Noohi, Forough ; Kennedy, Timothy E. ; Rochford, Joseph ; Bernard, Geneviève ; Teichmann, Martin ; Coulombe, Benoit ; Willis, Ian M. ; Kleinman, Claudia L. ; Brais, Bernard
Publisher:England: BioMed Central
Journal title:Molecular brain, 2017-04, Vol.10 (1), p.13-13, Article 13
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Newsletter articlesFull Text
IRCM scientists propose the existence of a new code in biology
Publisher:Ottawa: PR Newswire Association LLC
Journal title:Canada NewsWire, 2013
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Whole Exome/Genome Sequencing Joint Analysis of a Family with Oligogenic Familial Hypercholesterolemia
Author / Creator:Ghaleb, Youmna ; Elbitar, Sandy ; Philippi, Anne ; El Khoury, Petra ; Azar, Yara ; Andrianirina, Miangaly ; Loste, Alexia ; Abou-Khalil, Yara ; Nicolas, Gaël ; Le Borgne, Marie ; Moulin, Philippe ; Di-Filippo, Mathilde ; Charrière, Sybil ; Farnier, Michel ; Yelnick, Cécile ; Carreau, Valérie ; Ferrières, Jean ; Lecerf, Jean-Michel ; Derksen, Alexa ; Bernard, Geneviève ; Gauthier, Marie-Soleil ; Coulombe, Benoit ; Lütjohann, Dieter ; Fin, Bertrand ; Boland, Anne ; Olaso, Robert ; Deleuze, Jean-François ; Rabès, Jean-Pierre ; Boileau, Catherine ; Abifadel, Marianne ; Varret, Mathilde
Publisher:Switzerland: MDPI AG
Journal title:Metabolites, 2022-03, Vol.12 (3), p.262
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Newsletter articlesFull Text
A glimmer of hope for patients with leukodystrophies - Montreal researchers discover a new crucial gene associated with these orphan diseases
Publisher:Ottawa: PR Newswire Association LLC
Journal title:Canada NewsWire, 2015
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Newsletter articlesFull Text
A Canada-wide technology platform for mapping the human interactome coordinated at the IRCM in Montreal
Publisher:Ottawa: PR Newswire Association LLC
Journal title:Canada NewsWire, 2009
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ArticlesPeer ReviewedFull Text
Molecular dynamics and mutational analysis of the catalytic and translocation cycle of RNA polymerase
Author / Creator:Kireeva, Maria L ; Opron, Kristopher ; Seibold, Steve A ; Domecq, Céline ; Cukier, Robert I ; Coulombe, Benoit ; Kashlev, Mikhail ; Burton, Zachary F
Publisher:England: BioMed Central Ltd
Journal title:BMC biophysics, 2012-06, Vol.5 (1), p.11-11, Article 11
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Showing 1 to 20 of 37 results

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The CRAPome: a contaminant repository for affinity purification–mass spectrometry data

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R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein

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A Newly Uncovered Group of Distantly Related Lysine Methyltransferases Preferentially Interact with Molecular Chaperones to Regulate Their Activity

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Discovery of Antivirals Using Phage Display

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ARMC5 controls the degradation of most Pol II subunits, and ARMC5 mutation increases neural tube defect risks in mice and humans

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Recessive mutations in POLR1C cause a leukodystrophy by impairing biogenesis of RNA polymerase III

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How do our cells build their protein interactome?

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The 37TrillionCells initiative for improving global healthcare via cell-based interception and precision medicine: focus on neurodegenerative diseases

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Riluzole partially restores RNA polymerase III complex assembly in cells expressing the leukodystrophy-causative variant POLR3B R103H

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WIPO PUBLISHES PATENT OF SCA HYGIENE PRODUCTS, COULOMBE BENOIT FOR "METHOD AND APPARATUS FOR TRIMMING MATERIAL FROM A WEB" (CANADIAN INVENTOR)

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Structural and functional characterization of the IgSF21-neurexin2α complex and its related signaling pathways in the regulation of inhibitory synapse organization

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The leukodystrophy mutation Polr3b R103H causes homozygote mouse embryonic lethality and impairs RNA polymerase III biogenesis

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Towards a Treatment for Leukodystrophy Using Cell-Based Interception and Precision Medicine

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Interactome Analysis of KIN (Kin17) Shows New Functions of This Protein

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Absence of neurological abnormalities in mice homozygous for the Polr3a G672E hypomyelinating leukodystrophy mutation

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IRCM scientists propose the existence of a new code in biology

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Whole Exome/Genome Sequencing Joint Analysis of a Family with Oligogenic Familial Hypercholesterolemia

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A glimmer of hope for patients with leukodystrophies - Montreal researchers discover a new crucial gene associated with these orphan diseases

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A Canada-wide technology platform for mapping the human interactome coordinated at the IRCM in Montreal

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Molecular dynamics and mutational analysis of the catalytic and translocation cycle of RNA polymerase

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