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Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus
Author / Creator:Downes, Damien J. ; Cross, Amy R. ; Hua, Peng ; Roberts, Nigel ; Schwessinger, Ron ; Cutler, Antony J. ; Munis, Altar M. ; Brown, Jill ; Mielczarek, Olga ; de Andrea, Carlos E. ; Melero, Ignacio ; Gill, Deborah R. ; Hyde, Stephen C. ; Knight, Julian C. ; Todd, John A. ; Sansom, Stephen N. ; Issa, Fadi ; Davies, James O. J. ; Hughes, Jim R.
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2021-11, Vol.53 (11), p.1606-1615
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Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis
Author / Creator:Trzupek, Dominik ; Dunstan, Melanie ; Cutler, Antony J. ; Lee, Mercede ; Godfrey, Leila ; Jarvis, Lorna ; Rainbow, Daniel B. ; Aschenbrenner, Dominik ; Jones, Joanne L. ; Uhlig, Holm H. ; Wicker, Linda S. ; Todd, John A. ; Ferreira, Ricardo C.
Publisher:England: BioMed Central Ltd
Journal title:Genome medicine, 2020-06, Vol.12 (1), p.55-55, Article 55
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Functional IL6R 358Ala Allele Impairs Classical IL-6 Receptor Signaling and Influences Risk of Diverse Inflammatory Diseases
Author / Creator:Ferreira, Ricardo C. ; Freitag, Daniel F. ; Cutler, Antony J. ; Howson, Joanna M. M. ; Rainbow, Daniel B. ; Smyth, Deborah J. ; Kaptoge, Stephen ; Clarke, Pamela ; Boreham, Charlotte ; Coulson, Richard M. ; Pekalski, Marcin L. ; Chen, Wei-Min ; Onengut-Gumuscu, Suna ; Rich, Stephen S. ; Butterworth, Adam S. ; Malarstig, Anders ; Danesh, John ; Todd, John A.
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2013-04, Vol.9 (4), p.e1003444
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Chromosome contacts in activated T cells identify autoimmune disease candidate genes
Author / Creator:Burren, Oliver S. ; Rubio García, Arcadio ; Javierre, Biola-Maria ; Rainbow, Daniel B. ; Cairns, Jonathan ; Cooper, Nicholas J. ; Lambourne, John J. ; Schofield, Ellen ; Castro Dopico, Xaquin ; Ferreira, Ricardo C. ; Coulson, Richard ; Burden, Frances ; Rowlston, Sophia P. ; Downes, Kate ; Wingett, Steven W. ; Frontini, Mattia ; Ouwehand, Willem H. ; Fraser, Peter ; Spivakov, Mikhail ; Todd, John A. ; Wicker, Linda S. ; Cutler, Antony J. ; Wallace, Chris
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology, 2017-09, Vol.18 (1), p.165-165, Article 165
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Using de novo assembly to identify structural variation of eight complex immune system gene regions
Author / Creator:Zhang, Jia-Yuan ; Roberts, Hannah ; Flores, David S. C. ; Cutler, Antony J. ; Brown, Andrew C. ; Whalley, Justin P. ; Mielczarek, Olga ; Buck, David ; Lockstone, Helen ; Xella, Barbara ; Oliver, Karen ; Corton, Craig ; Betteridge, Emma ; Bashford-Rogers, Rachael ; Knight, Julian C. ; Todd, John A. ; Band, Gavin
Publisher:United States: Public Library of Science
Journal title:PLoS computational biology, 2021-08, Vol.17 (8), p.e1009254-e1009254
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Thymocyte regulatory variant alters transcription factor binding and protects from type 1 diabetes in infants
Author / Creator:Sandholm, Niina ; Rubio García, Arcadio ; Pekalski, Marcin L. ; Inshaw, Jamie R. J. ; Cutler, Antony J. ; Todd, John A.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-08, Vol.12 (1), p.14137-14137, Article 14137
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Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping
Author / Creator:Wallace, Chris ; Cutler, Antony J ; Pontikos, Nikolas ; Pekalski, Marcin L ; Burren, Oliver S ; Cooper, Jason D ; García, Arcadio Rubio ; Ferreira, Ricardo C ; Guo, Hui ; Walker, Neil M ; Smyth, Deborah J ; Rich, Stephen S ; Onengut-Gumuscu, Suna ; Sawcer, Stephen J ; Ban, Maria ; Richardson, Sylvia ; Todd, John A ; Wicker, Linda S
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2015-06, Vol.11 (6), p.e1005272-e1005272
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Nippostrongylus-Induced Intestinal Hypercontractility Requires IL-4 Receptor Alpha-Responsiveness by T Cells in Mice
Author / Creator:Schmidt, Saskia ; Hoving, J. Claire ; Horsnell, William G. C. ; Mearns, Helen ; Cutler, Antony J. ; Brombacher, Tiroyaone M. ; Brombacher, Frank
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-12, Vol.7 (12), p.e52211-e52211
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Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes
Author / Creator:Robertson, Catherine C. ; Inshaw, Jamie R. J. ; Onengut-Gumuscu, Suna ; Chen, Wei-Min ; Santa Cruz, David Flores ; Yang, Hanzhi ; Cutler, Antony J. ; Crouch, Daniel J. M. ; Farber, Emily ; Bridges, S. Louis ; Edberg, Jeffrey C. ; Kimberly, Robert P. ; Buckner, Jane H. ; Deloukas, Panos ; Divers, Jasmin ; Dabelea, Dana ; Lawrence, Jean M. ; Marcovina, Santica ; Shah, Amy S. ; Greenbaum, Carla J. ; Atkinson, Mark A. ; Gregersen, Peter K. ; Oksenberg, Jorge R. ; Pociot, Flemming ; Rewers, Marian J. ; Steck, Andrea K. ; Dunger, David B. ; Wicker, Linda S. ; Concannon, Patrick ; Todd, John A. ; Rich, Stephen S.
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2021-07, Vol.53 (7), p.962-971
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Protein kinase C δ is essential for optimal macrophage-mediated phagosomal containment of Listeria monocytogenes
Author / Creator:Schwegmann, Anita ; Guler, Reto ; Cutler, Antony J ; Arendse, Berenice ; Horsnell, William G.C ; Flemming, Alexandra ; Kottmann, Andreas H ; Ryan, Gregory ; Hide, Winston ; Leitges, Michael ; Seoighe, Cathal ; Brombacher, Frank
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2007-10, Vol.104 (41), p.16251-16256
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ArticlesPeer ReviewedFull Text
Approaches and advances in the genetic causes of autoimmune disease and their implications
Author / Creator:Inshaw, Jamie R. J. ; Cutler, Antony J. ; Burren, Oliver S. ; Stefana, M. Irina ; Todd, John A.
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2018-07, Vol.19 (7), p.674-684
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IL-21 production by CD4+ effector T cells and frequency of circulating follicular helper T cells are increased in type 1 diabetes patients
Author / Creator:Ferreira, Ricardo C. ; Simons, Henry Z. ; Thompson, Whitney S. ; Cutler, Antony J. ; Dopico, Xaquin Castro ; Smyth, Deborah J. ; Mashar, Meghavi ; Schuilenburg, Helen ; Walker, Neil M. ; Dunger, David B. ; Wallace, Chris ; Todd, John A. ; Wicker, Linda S. ; Pekalski, Marcin L.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Diabetologia, 2015-04, Vol.58 (4), p.781-790
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Capturing the systemic immune signature of a norovirus infection: an n-of-1 case study within a clinical trial
Author / Creator:Cutler, Antony J. ; Oliveira, Joao ; Ferreira, Ricardo C. ; Challis, Ben ; Walker, Neil M. ; Caddy, Sarah ; Lu, Jia ; Stevens, Helen E. ; Smyth, Deborah J. ; Pekalski, Marcin L. ; Kennet, Jane ; Hunter, Kara M.D. ; Goodfellow, Ian ; Wicker, Linda S. ; Todd, John A. ; Waldron-Lynch, Frank
Publisher:England: Wellcome Trust Limited
Journal title:Wellcome open research, 2017, Vol.2, p.28-28
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FcγRIIb controls bone marrow plasma cell persistence and apoptosis
Author / Creator:Xiang, Zou ; Cutler, Antony J ; Brownlie, Rebecca J ; Fairfax, Kirsten ; Lawlor, Kate E ; Severinson, Eva ; Walker, Elizabeth U ; Manz, Rudolf A ; Tarlinton, David M ; Smith, Kenneth G C
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2007-04, Vol.8 (4), p.419-429
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Interleukin 13-mediated colitis in the absence of IL-4Rα signalling
Author / Creator:Hoving, Jennifer C ; Cutler, Antony J ; Leeto, Mosiuoa ; Horsnell, William G C ; Dewals, Benjamin G ; Nieuwenhuizen, Natalie E ; Brombacher, Frank
Publisher:England: BMJ Group
Journal title:Gut, 2017-11, Vol.66 (11), p.2037-2039
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Author Correction: Approaches and advances in the genetic causes of autoimmune disease and their implications
Author / Creator:Inshaw, Jamie R. J. ; Cutler, Antony J. ; Burren, Oliver S. ; Stefana, M. Irina ; Todd, John A.
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2020-06, Vol.21 (6), p.695-695
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Publisher Correction: Approaches and advances in the genetic causes of autoimmune disease and their implications
Author / Creator:Inshaw, Jamie R. J. ; Cutler, Antony J. ; Burren, Oliver S. ; Stefana, M. Irina ; Todd, John A.
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2019-03, Vol.20 (3), p.375-375
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Deletion of IL-4Ralpha on CD4 T cells renders BALB/c mice resistant to Leishmania major infection
Author / Creator:Radwanska, Magdalena ; Cutler, Antony J ; Hoving, J Claire ; Magez, Stefan ; Holscher, Christoph ; Bohms, Andreas ; Arendse, Berenice ; Kirsch, Richard ; Hunig, Thomas ; Alexander, James ; Kaye, Paul ; Brombacher, Frank
Publisher:United States: Public Library of Science (PLoS)
Journal title:PLoS pathogens, 2007-05, Vol.3 (5), p.e68-e68
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Correction: Delayed Goblet Cell Hyperplasia, Acetylcholine Receptor Expression, and Worm Expulsion in SMC-Specific IL-4Rα–Deficient Mice
Author / Creator:Horsnell, William G. C. ; Cutler, Antony J. ; Hoving, J. Claire ; Mearns, Helen ; Myburgh, Elmarie ; Arendse, Berenice ; Finkelman, Fred D. ; Owens, Gary K. ; Erle, Dave ; Brombacher, Frank
Publisher:San Francisco, USA: Public Library of Science
Journal title:PLoS pathogens, 2007-04, Vol.3 (4), p.e37
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Delayed goblet cell hyperplasia, acetylcholine receptor expression, and worm expulsion in SMC-specific IL-4Ralpha-deficient mice
Author / Creator:Horsnell, William G C ; Cutler, Antony J ; Hoving, J Claire ; Hoving, Claire J ; Mearns, Helen ; Myburgh, Elmarie ; Arendse, Berenice ; Finkelman, Fred D ; Owens, Gary K ; Erle, Dave ; Brombacher, Frank
Publisher:United States: Public Library of Science (PLoS)
Journal title:PLoS pathogens, 2007-01, Vol.3 (1), p.e1-e1
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Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus

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Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis

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Functional IL6R 358Ala Allele Impairs Classical IL-6 Receptor Signaling and Influences Risk of Diverse Inflammatory Diseases

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Chromosome contacts in activated T cells identify autoimmune disease candidate genes

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Using de novo assembly to identify structural variation of eight complex immune system gene regions

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Thymocyte regulatory variant alters transcription factor binding and protects from type 1 diabetes in infants

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Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping

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Nippostrongylus-Induced Intestinal Hypercontractility Requires IL-4 Receptor Alpha-Responsiveness by T Cells in Mice

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Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes

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Protein kinase C δ is essential for optimal macrophage-mediated phagosomal containment of Listeria monocytogenes

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Approaches and advances in the genetic causes of autoimmune disease and their implications

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IL-21 production by CD4+ effector T cells and frequency of circulating follicular helper T cells are increased in type 1 diabetes patients

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Capturing the systemic immune signature of a norovirus infection: an n-of-1 case study within a clinical trial

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FcγRIIb controls bone marrow plasma cell persistence and apoptosis

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Interleukin 13-mediated colitis in the absence of IL-4Rα signalling

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Author Correction: Approaches and advances in the genetic causes of autoimmune disease and their implications

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Publisher Correction: Approaches and advances in the genetic causes of autoimmune disease and their implications

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Deletion of IL-4Ralpha on CD4 T cells renders BALB/c mice resistant to Leishmania major infection

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Correction: Delayed Goblet Cell Hyperplasia, Acetylcholine Receptor Expression, and Worm Expulsion in SMC-Specific IL-4Rα–Deficient Mice

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Delayed goblet cell hyperplasia, acetylcholine receptor expression, and worm expulsion in SMC-specific IL-4Ralpha-deficient mice

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