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ArticlesPeer ReviewedFull Text
The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation
Author / Creator:Baumli, Sonja ; Lolli, Graziano ; Lowe, Edward D ; Troiani, Sonia ; Rusconi, Luisa ; Bullock, Alex N ; Debreczeni, Judit É ; Knapp, Stefan ; Johnson, Louise N
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2008-07, Vol.27 (13), p.1907-1918
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The novel quantitative trait locus GL3.1 controls rice grain size and yield by regulating Cyclin-T1;3
Author / Creator:Qi, Peng ; Lin, You-Shun ; Song, Xian-Jun ; Shen, Jin-Bo ; Huang, Wei ; Shan, Jun-Xiang ; Zhu, Mei-Zhen ; Jiang, Liwen ; Gao, Ji-Ping ; Lin, Hong-Xuan
Publisher:London: Nature Publishing Group UK
Journal title:Cell research, 2012-12, Vol.22 (12), p.1666-1680
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Reversible phosphorylation of cyclin T1 promotes assembly and stability of P-TEFb
Author / Creator:Huang, Fang ; Nguyen, Trang Tt ; Echeverria, Ignacia ; Rakesh, Ramachandran ; Cary, Daniele C ; Paculova, Hana ; Sali, Andrej ; Weiss, Arthur ; Peterlin, Boris Matija ; Fujinaga, Koh
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2021-11, Vol.10
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A Truncated Isoform of Cyclin T1 Could Contribute to the Non-Permissive HIV-1 Phenotype of U937 Promonocytic Cells
Author / Creator:Alberio, Tiziana ; Shallak, Mariam ; Shaik, Amruth Kaleem Basha ; Accolla, Roberto Sergio ; Forlani, Greta
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2024-07, Vol.16 (8), p.1176
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miR-198 inhibits HIV-1 gene expression and replication in monocytes and its mechanism of action appears to involve repression of cyclin T1
Author / Creator:Sung, Tzu-Ling ; Rice, Andrew P
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2009-01, Vol.5 (1), p.e1000263
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The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription
Author / Creator:Yang, Zhiyuan ; Zhu, Qingwei ; Luo, Kunxin ; Zhou, Qiang
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2001-11, Vol.414 (6861), p.317-322
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Regulation of cyclin T1 during HIV replication and latency establishment in human memory CD4 T cells
Author / Creator:Couturier, Jacob ; Orozco, Aaron F ; Liu, Hongbing ; Budhiraja, Sona ; Siwak, Edward B ; Nehete, Pramod N ; Sastry, K Jagannadha ; Rice, Andrew P ; Lewis, Dorothy E
Publisher:England: BioMed Central Ltd
Journal title:Virology journal, 2019-02, Vol.16 (1), p.22-22, Article 22
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Acetylation of cyclin T1 regulates the equilibrium between active and inactive P-TEFb in cells
Author / Creator:Cho, Sungyoo ; Schroeder, Sebastian ; Kaehlcke, Katrin ; Kwon, Hye-Sook ; Pedal, Angelika ; Herker, Eva ; Schnoelzer, Martina ; Ott, Melanie
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2009-05, Vol.28 (10), p.1407-1417
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Ligand- and structure-based pharmacophore modeling, docking study reveals 2-[[4-[6-(isopropylamino) pyrimidin-4-yl]-1H-pyrrolo[2,3-b] pyridin-6-yl] amino] ethanol as a potential anticancer agent of CD...
Author / Creator:Hussain, Afzal ; Verma, Chandan
Publisher:India: Wolters Kluwer India Pvt. Ltd
Journal title:Journal of cancer research and therapeutics, 2019-07, Vol.15 (5), p.1131-1140
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Molecular dynamics simulation and experimental verification of the interaction between cyclin T1 and HIV-1 Tat proteins
Author / Creator:Asamitsu, Kaori ; Hirokawa, Takatsugu ; Hibi, Yurina ; Okamoto, Takashi
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-03, Vol.10 (3), p.e0119451-e0119451
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Mice transgenic for CD4-specific human CD4, CCR5 and cyclin T1 expression: a new model for investigating HIV-1 transmission and treatment efficacy
Author / Creator:Seay, Kieran ; Qi, Xiaohua ; Zheng, Jian Hua ; Zhang, Cong ; Chen, Ken ; Dutta, Monica ; Deneroff, Kathryn ; Ochsenbauer, Christina ; Kappes, John C ; Littman, Dan R ; Goldstein, Harris
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-05, Vol.8 (5), p.e63537-e63537
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MD simulation of the Tat/Cyclin T1/CDK9 complex revealing the hidden catalytic cavity within the CDK9 molecule upon Tat binding
Author / Creator:Asamitsu, Kaori ; Hirokawa, Takatsugu ; Okamoto, Takashi
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-02, Vol.12 (2), p.e0171727-e0171727
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Differential acetylation of Tat coordinates its interaction with the co-activators cyclin T1 and PCAF
Author / Creator:Brès, Vanessa ; Tagami, Hideaki ; Péloponèse, Jean-Marie ; Loret, Erwan ; Jeang, Kuan-Teh ; Nakatani, Yoshihiro ; Emiliani, Stephane ; Benkirane, Monsef ; Kiernan, Rosemary E.
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2002-12, Vol.21 (24), p.6811-6819
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Effects of prostratin on Cyclin T1/P-TEFb function and the gene expression profile in primary resting CD4+ T cells
Author / Creator:Sung, Tzu-Ling ; Rice, Andrew P
Publisher:England: BioMed Central Ltd
Journal title:Retrovirology, 2006-10, Vol.3 (1), p.66-66, Article 66
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A Cyclin T1 point mutation that abolishes positive transcription elongation factor (P-TEFb) binding to Hexim1 and HIV tat
Author / Creator:Verstraete, Nina ; Kuzmina, Alona ; Diribarne, Gaelle ; Nguyen, Van Trung ; Kobbi, Lydia ; Ludanyi, Monika ; Taube, Ran ; Bensaude, Olivier
Publisher:England: BioMed Central Ltd
Journal title:Retrovirology, 2014-07, Vol.11 (1), p.50-50, Article 50
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Structural insights into the Cyclin T1–Tat–TAR RNA transcription activation complex from EIAV
Author / Creator:Anand, Kanchan ; Schulte, Antje ; Vogel-Bachmayr, Karin ; Scheffzek, Klaus ; Geyer, Matthias
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2008-12, Vol.15 (12), p.1287-1292
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Determining the Functions of HIV-1 Tat and a Second Magnesium Ion in the CDK9/Cyclin T1 Complex: A Molecular Dynamics Simulation Study
Author / Creator:Jin, Hai-Xiao ; Go, Mei-Lin ; Yin, Peng ; Qiu, Xiao-Ting ; Zhu, Peng ; Yan, Xiao-Jun
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-04, Vol.10 (4), p.e0124673-e0124673
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Mice transgenic for equine cyclin T1 and ELR1 are susceptible to equine infectious anemia virus infection
Author / Creator:Du, Cheng ; Ma, Jian ; Liu, Qiang ; Li, Yun-Fei ; He, Xi-Jun ; Lin, Yue-Zhi ; Wang, Xue-Feng ; Meng, Qing-Wen ; Wang, Xiaojun ; Zhou, Jian-Hua
Publisher:England: BioMed Central Ltd
Journal title:Retrovirology, 2015-04, Vol.12 (1), p.36-36, Article 36
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Increased cyclin T1 expression as a favorable prognostic factor in treating gastric adenocarcinoma
Author / Creator:JIN, JONG-SHIAW ; LIN, LIEN-FU ; CHEN, JUI-CHANG ; HUANG, CHIA-CHI ; SHEU, JENG-HORNG ; CHEN, WENLUNG ; TSAO, TANG-YI ; HSU, CHIH-WEI
Publisher:Greece: D.A. Spandidos
Journal title:Oncology letters, 2015-12, Vol.10 (6), p.3712-3718
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The breast cell growth inhibitor, estrogen down regulated gene 1, modulates a novel functional interaction between estrogen receptor alpha and transcriptional elongation factor cyclin T1
Author / Creator:Wittmann, Bryan M ; Fujinaga, Koh ; Deng, Huayun ; Ogba, Ndiya ; Montano, Monica M
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2005-08, Vol.24 (36), p.5576-5588
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The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation

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The novel quantitative trait locus GL3.1 controls rice grain size and yield by regulating Cyclin-T1;3

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Reversible phosphorylation of cyclin T1 promotes assembly and stability of P-TEFb

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A Truncated Isoform of Cyclin T1 Could Contribute to the Non-Permissive HIV-1 Phenotype of U937 Promonocytic Cells

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miR-198 inhibits HIV-1 gene expression and replication in monocytes and its mechanism of action appears to involve repression of cyclin T1

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The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription

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Regulation of cyclin T1 during HIV replication and latency establishment in human memory CD4 T cells

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Acetylation of cyclin T1 regulates the equilibrium between active and inactive P-TEFb in cells

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Ligand- and structure-based pharmacophore modeling, docking study reveals 2-[[4-[6-(isopropylamino) pyrimidin-4-yl]-1H-pyrrolo[2,3-b] pyridin-6-yl] amino] ethanol as a potential anticancer agent of CD...

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Molecular dynamics simulation and experimental verification of the interaction between cyclin T1 and HIV-1 Tat proteins

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Mice transgenic for CD4-specific human CD4, CCR5 and cyclin T1 expression: a new model for investigating HIV-1 transmission and treatment efficacy

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MD simulation of the Tat/Cyclin T1/CDK9 complex revealing the hidden catalytic cavity within the CDK9 molecule upon Tat binding

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Differential acetylation of Tat coordinates its interaction with the co-activators cyclin T1 and PCAF

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Effects of prostratin on Cyclin T1/P-TEFb function and the gene expression profile in primary resting CD4+ T cells

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A Cyclin T1 point mutation that abolishes positive transcription elongation factor (P-TEFb) binding to Hexim1 and HIV tat

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Structural insights into the Cyclin T1–Tat–TAR RNA transcription activation complex from EIAV

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Determining the Functions of HIV-1 Tat and a Second Magnesium Ion in the CDK9/Cyclin T1 Complex: A Molecular Dynamics Simulation Study

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Mice transgenic for equine cyclin T1 and ELR1 are susceptible to equine infectious anemia virus infection

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Increased cyclin T1 expression as a favorable prognostic factor in treating gastric adenocarcinoma

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The breast cell growth inhibitor, estrogen down regulated gene 1, modulates a novel functional interaction between estrogen receptor alpha and transcriptional elongation factor cyclin T1

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