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ArticlesPeer ReviewedFull Text
Candidalysin is a fungal peptide toxin critical for mucosal infection
Author / Creator:Moyes, David L. ; Wilson, Duncan ; Richardson, Jonathan P. ; Mogavero, Selene ; Tang, Shirley X. ; Wernecke, Julia ; Höfs, Sarah ; Gratacap, Remi L. ; Robbins, Jon ; Runglall, Manohursingh ; Murciano, Celia ; Blagojevic, Mariana ; Thavaraj, Selvam ; Förster, Toni M. ; Hebecker, Betty ; Kasper, Lydia ; Vizcay, Gema ; Iancu, Simona I. ; Kichik, Nessim ; Häder, Antje ; Kurzai, Oliver ; Luo, Ting ; Krüger, Thomas ; Kniemeyer, Olaf ; Cota, Ernesto ; Bader, Oliver ; Wheeler, Robert T. ; Gutsmann, Thomas ; Hube, Bernhard ; Naglik, Julian R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-04, Vol.532 (7597), p.64-68
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Release of Staphylococcus aureus extracellular vesicles and their application as a vaccine platform
Author / Creator:Wang, Xiaogang ; Thompson, Christopher D. ; Weidenmaier, Christopher ; Lee, Jean C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-04, Vol.9 (1), p.1379-13, Article 1379
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The amphibian antimicrobial peptide uperin 3.5 is a cross-α/cross-β chameleon functional amyloid
Author / Creator:Salinas, Nir ; Tayeb-Fligelman, Einav ; Sammito, Massimo D. ; Bloch, Daniel ; Jelinek, Raz ; Noy, Dror ; Usón, Isabel ; Landau, Meytal
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-01, Vol.118 (3), p.1-8
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Reprogramming cholesterol metabolism in macrophages and its role in host defense against cholesterol-dependent cytolysins
Author / Creator:Lee, Min-Sub ; Bensinger, Steven J.
Publisher:London: Nature Publishing Group UK
Journal title:Cellular & molecular immunology, 2022-03, Vol.19 (3), p.327-336
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Fidaxomicin Preserves the Intestinal Microbiome During and After Treatment of Clostridium difficile Infection (CDI) and Reduces Both Toxin Reexpression and Recurrence of CDI
Author / Creator:Louie, Thomas J. ; Cannon, Kris ; Byrne, Brendan ; Emery, Judy ; Ward, Linda ; Eyben, Melissa ; Krulicki, Walter
Publisher:United States: Oxford University Press
Journal title:Clinical infectious diseases, 2012-08, Vol.55 (suppl 2), p.S132-S142
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The cell envelope of Staphylococcus aureus selectively controls the sorting of virulence factors
Author / Creator:Zheng, Xuhui ; Marsman, Gerben ; Lacey, Keenan A. ; Chapman, Jessica R. ; Goosmann, Christian ; Ueberheide, Beatrix M. ; Torres, Victor J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-10, Vol.12 (1), p.6193-16, Article 6193
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Crystal structure of an invertebrate cytolysin pore reveals unique properties and mechanism of assembly
Author / Creator:Podobnik, Marjetka ; Savory, Peter ; Rojko, Nejc ; Kisovec, Matic ; Wood, Neil ; Hambley, Richard ; Pugh, Jonathan ; Wallace, E. Jayne ; McNeill, Luke ; Bruce, Mark ; Liko, Idlir ; Allison, Timothy M. ; Mehmood, Shahid ; Yilmaz, Neval ; Kobayashi, Toshihide ; Gilbert, Robert J. C. ; Robinson, Carol V. ; Jayasinghe, Lakmal ; Anderluh, Gregor
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-05, Vol.7 (1), p.11598-10, Article 11598
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ArticlesPeer ReviewedFull Text
Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide
Author / Creator:Freudenthal, Bret D. ; Beard, William A. ; Perera, Lalith ; Shock, David D. ; Kim, Taejin ; Schlick, Tamar ; Wilson, Samuel H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-01, Vol.517 (7536), p.635-639
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Genome-based discovery and total synthesis of janustatins, potent cytotoxins from a plant-associated bacterium
Author / Creator:Ueoka, Reiko ; Sondermann, Philipp ; Leopold-Messer, Stefan ; Liu, Yizhou ; Suo, Rei ; Bhushan, Agneya ; Vadakumchery, Lida ; Greczmiel, Ute ; Yashiroda, Yoko ; Kimura, Hiromi ; Nishimura, Shinichi ; Hoshikawa, Yojiro ; Yoshida, Minoru ; Oxenius, Annette ; Matsunaga, Shigeki ; Williamson, R. Thomas ; Carreira, Erick M. ; Piel, Jörn
Publisher:London: Nature Publishing Group UK
Journal title:Nature chemistry, 2022-10, Vol.14 (10), p.1193-1201
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ArticlesPeer ReviewedFull Text
Apolipoprotein L-1 renal risk variants form active channels at the plasma membrane driving cytotoxicity
Author / Creator:Giovinazzo, Joseph A ; Thomson, Russell P ; Khalizova, Nailya ; Zager, Patrick J ; Malani, Nirav ; Rodriguez-Boulan, Enrique ; Raper, Jayne ; Schreiner, Ryan
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2020-05, Vol.9
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ArticlesPeer ReviewedFull Text
Inerolysin and vaginolysin, the cytolysins implicated in vaginal dysbiosis, differently impair molecular integrity of phospholipid membranes
Author / Creator:Ragaliauskas, Tadas ; Plečkaitytė, Milda ; Jankunec, Marija ; Labanauskas, Linas ; Baranauskiene, Lina ; Valincius, Gintaras
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-07, Vol.9 (1), p.10606-11, Article 10606
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ArticlesPeer ReviewedFull Text
Tc toxin activation requires unfolding and refolding of a β-propeller
Author / Creator:Gatsogiannis, Christos ; Merino, Felipe ; Roderer, Daniel ; Balchin, David ; Schubert, Evelyn ; Kuhlee, Anne ; Hayer-Hartl, Manajit ; Raunser, Stefan
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2018-11, Vol.563 (7730), p.209-213
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ArticlesPeer ReviewedFull Text
Biological reactivity of zinc oxide nanoparticles with mammalian test systems: an overview
Author / Creator:Saptarshi, Shruti R ; Duschl, Albert ; Lopata, Andreas L
Publisher:England: Future Medicine Ltd
Journal title:Nanomedicine (London, England), 2015-07, Vol.10 (13), p.2075-2092
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ArticlesPeer ReviewedFull Text
Escherichia coli Induces DNA Double-Strand Breaks in Eukaryotic Cells
Author / Creator:Nougayrède, Jean-Philippe ; Homburg, Stefan ; Taieb, Frédéric ; Boury, Michèle ; Brzuszkiewicz, Elzbieta ; Gottschalk, Gerhard ; Buchrieser, Carmen ; Hacker, Jörg ; Dobrindt, Ulrich ; Oswald, Eric
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2006-08, Vol.313 (5788), p.848-851
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ArticlesPeer ReviewedFull Text
Additive function of Vibrio vulnificus MARTX(Vv) and VvhA cytolysins promotes rapid growth and epithelial tissue necrosis during intestinal infection
Author / Creator:Jeong, Hee-Gon ; Satchell, Karla J F
Publisher:United States: Public Library of Science (PLoS)
Journal title:PLoS pathogens, 2012, Vol.8 (3), p.e1002581
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ArticlesPeer ReviewedFull Text
Structural investigation of interactions between halogenated flavonoids and the lipid membrane along with their role as cytotoxic agents
Author / Creator:Dudek, Anita ; Szulc, Natalia ; Pawlak, Aleksandra ; Strugała-Danak, Paulina ; Krawczyk-Łebek, Agnieszka ; Perz, Martyna ; Kostrzewa-Susłow, Edyta ; Pruchnik, Hanna
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-05, Vol.14 (1), p.10561-16, Article 10561
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Cytolysin A is an intracellularly induced and secreted cytotoxin of typhoidal Salmonella
Author / Creator:Krone, Lena ; Mahankali, Srujita ; Geiger, Tobias
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-09, Vol.15 (1), p.8414-15, Article 8414
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Chemical composition, antioxidant, anti-inflammatory, and cytotoxic activities of Opuntia stricta cladodes
Author / Creator:Izuegbuna, Ogochukwu ; Otunola, Gloria ; Bradley, Graeme
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-01, Vol.14 (1), p.e0209682-e0209682
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Structural basis for tuning activity and membrane specificity of bacterial cytolysins
Author / Creator:Shah, Nita R. ; Voisin, Tomas B. ; Parsons, Edward S. ; Boyd, Courtney M. ; Hoogenboom, Bart W. ; Bubeck, Doryen
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-11, Vol.11 (1), p.5818-10, Article 5818
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Distant relatives of a eukaryotic cell-specific toxin family evolved a complement-like mechanism to kill bacteria
Author / Creator:Abrahamsen, Hunter L. ; Sanford, Tristan C. ; Collamore, Casie E. ; Johnstone, Bronte A. ; Coyne, Michael J. ; García-Bayona, Leonor ; Christie, Michelle P. ; Evans, Jordan C. ; Farrand, Allison J. ; Flores, Katia ; Morton, Craig J. ; Parker, Michael W. ; Comstock, Laurie E. ; Tweten, Rodney K.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-06, Vol.15 (1), p.5028-15, Article 5028
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Candidalysin is a fungal peptide toxin critical for mucosal infection

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Release of Staphylococcus aureus extracellular vesicles and their application as a vaccine platform

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The amphibian antimicrobial peptide uperin 3.5 is a cross-α/cross-β chameleon functional amyloid

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Reprogramming cholesterol metabolism in macrophages and its role in host defense against cholesterol-dependent cytolysins

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Fidaxomicin Preserves the Intestinal Microbiome During and After Treatment of Clostridium difficile Infection (CDI) and Reduces Both Toxin Reexpression and Recurrence of CDI

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The cell envelope of Staphylococcus aureus selectively controls the sorting of virulence factors

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Crystal structure of an invertebrate cytolysin pore reveals unique properties and mechanism of assembly

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Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide

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Genome-based discovery and total synthesis of janustatins, potent cytotoxins from a plant-associated bacterium

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Apolipoprotein L-1 renal risk variants form active channels at the plasma membrane driving cytotoxicity

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Inerolysin and vaginolysin, the cytolysins implicated in vaginal dysbiosis, differently impair molecular integrity of phospholipid membranes

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Tc toxin activation requires unfolding and refolding of a β-propeller

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Biological reactivity of zinc oxide nanoparticles with mammalian test systems: an overview

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Escherichia coli Induces DNA Double-Strand Breaks in Eukaryotic Cells

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Additive function of Vibrio vulnificus MARTX(Vv) and VvhA cytolysins promotes rapid growth and epithelial tissue necrosis during intestinal infection

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Structural investigation of interactions between halogenated flavonoids and the lipid membrane along with their role as cytotoxic agents

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Cytolysin A is an intracellularly induced and secreted cytotoxin of typhoidal Salmonella

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Chemical composition, antioxidant, anti-inflammatory, and cytotoxic activities of Opuntia stricta cladodes

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Structural basis for tuning activity and membrane specificity of bacterial cytolysins

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Distant relatives of a eukaryotic cell-specific toxin family evolved a complement-like mechanism to kill bacteria

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