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138 results for Dipeptidases+-+metabolism

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ArticlesPeer ReviewedFull Text
Current Understanding of the Emerging Role of Prolidase in Cellular Metabolism
Author / Creator:Misiura, Magdalena ; Miltyk, Wojciech
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-08, Vol.21 (16), p.5906
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DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis
Author / Creator:Okondo, Marian C ; Johnson, Darren C ; Sridharan, Ramya ; Go, Eun Bin ; Chui, Ashley J ; Wang, Mitchell S ; Poplawski, Sarah E ; Wu, Wengen ; Liu, Yuxin ; Lai, Jack H ; Sanford, David G ; Arciprete, Michael O ; Golub, Todd R ; Bachovchin, William W ; Bachovchin, Daniel A
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2017-01, Vol.13 (1), p.46-53
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Aminopeptidases trim Xaa-Pro proteins, initiating their degradation by the Pro/N-degron pathway
Author / Creator:Chen, Shun-Jia ; Kim, Leehyeon ; Song, Hyun Kyu ; Varshavsky, Alexander
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-10, Vol.118 (43), p.1-7
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A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis
Author / Creator:Guan, Yuting ; Liang, Xiujie ; Ma, Ziyuan ; Hu, Hailong ; Liu, Hongbo ; Miao, Zhen ; Linkermann, Andreas ; Hellwege, Jacklyn N. ; Voight, Benjamin F. ; Susztak, Katalin
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-08, Vol.12 (1), p.5078-17, Article 5078
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N-lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids
Author / Creator:Jansen, Robert S. ; Addie, Ruben ; Merkx, Remco ; Fish, Alexander ; Mahakena, Sunny ; Bleijerveld, Onno B. ; Altelaar, Maarten ; IJlst, Lodewijk ; Wanders, Ronald J. ; Borst, P. ; van de Wetering, Koen
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2015-05, Vol.112 (21), p.6601-6606
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State of the Art in the Development of Human Serum Carnosinase Inhibitors
Author / Creator:Regazzoni, Luca
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2024-06, Vol.29 (11), p.2488
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DPP8/9 inhibitors activate the CARD8 inflammasome in resting lymphocytes
Author / Creator:Johnson, Darren C. ; Okondo, Marian C. ; Orth, Elizabeth L. ; Rao, Sahana D. ; Huang, Hsin-Che ; Ball, Daniel P. ; Bachovchin, Daniel A.
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2020-08, Vol.11 (8), p.628-628, Article 628
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Sulphostin-inspired N-phosphonopiperidones as selective covalent DPP8 and DPP9 inhibitors
Author / Creator:Sewald, Leonard ; Tabak, Werner W. A. ; Fehr, Lorenz ; Zolg, Samuel ; Najdzion, Maja ; Verhoef, Carlo J. A. ; Podlesainski, David ; Geiss-Friedlander, Ruth ; Lammens, Alfred ; Kaschani, Farnusch ; Hellerschmied, Doris ; Huber, Robert ; Kaiser, Markus
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-04, Vol.16 (1), p.3208-15, Article 3208
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CNDP1 Overexpression by Promoter Hypomethylation Predicts Poor Prognosis and Immunotherapy Response in Mucosal Melanoma
Author / Creator:Jia, Jia ; Gu, Junjie ; Gao, Lina ; Liu, Kaihua ; Dai, Jie ; Zhang, Fanshuang ; Yuan, Pei ; Mao, Lili ; Wei, Xiaoting ; Shao, Yang ; Guo, Jun ; Xi, Yanfeng ; Ying, Jianming ; Si, Lu
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2025-06, Vol.116 (6), p.1671-1678
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ArticlesPeer ReviewedFull Text
Exploring Secondary Amine Carnosine Derivatives: Design, Synthesis, and Properties
Author / Creator:Artasensi, Angelica ; Mazzotta, Sarah ; Sanz, Ines ; Lin, Licheng ; Vistoli, Giulio ; Fumagalli, Laura ; Regazzoni, Luca
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2024-11, Vol.29 (21), p.5083
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ArticlesPeer ReviewedFull Text
Erythrocytes Prevent Degradation of Carnosine by Human Serum Carnosinase
Author / Creator:Oppermann, Henry ; Elsel, Stefanie ; Birkemeyer, Claudia ; Meixensberger, Jürgen ; Gaunitz, Frank
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2021-11, Vol.22 (23), p.12802
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ArticlesPeer ReviewedFull Text
Carnosine Attenuates the Development of both Type 2 Diabetes and Diabetic Nephropathy in BTBR ob/ob Mice
Author / Creator:Albrecht, Thomas ; Schilperoort, Maaike ; Zhang, Shiqi ; Braun, Jana D. ; Qiu, Jiedong ; Rodriguez, Angelica ; Pastene, Diego O. ; Krämer, Bernhard K. ; Köppel, Hannes ; Baelde, Hans ; de Heer, Emile ; Anna Altomare, Alessandra ; Regazzoni, Luca ; Denisi, Alessandra ; Aldini, Giancarlo ; van den Born, Jacob ; Yard, Benito A. ; Hauske, Sibylle J.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-03, Vol.7 (1), p.44492-44492, Article 44492
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ArticlesPeer ReviewedFull Text
Multiplex gene knockout raises Ala-Gln production by Escherichia coli expressing amino acid ester acyltransferase
Author / Creator:Jing, Zhanyu ; Xu, Jian ; Liu, Jia ; Du, Cong ; Qi, Jiakun ; Fan, Chao ; Li, Yimin ; Yuan, Wenjie
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Applied microbiology and biotechnology, 2023-06, Vol.107 (11), p.3523-3533
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GroEL actively stimulates folding of the endogenous substrate protein PepQ
Author / Creator:Weaver, Jeremy ; Jiang, Mengqiu ; Roth, Andrew ; Puchalla, Jason ; Zhang, Junjie ; Rye, Hays S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-06, Vol.8 (1), p.15934-15934, Article 15934
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DPEP1 is a direct target of miR-193a-5p and promotes hepatoblastoma progression by PI3K/Akt/mTOR pathway
Author / Creator:Cui, Xichun ; Liu, Xin ; Han, Qicai ; Zhu, Jianming ; Li, Jianhao ; Ren, Zhigang ; Liu, Liwen ; Luo, Yanbing ; Wang, Zhifang ; Zhang, Dandan ; Fan, Yingzhong ; Zhang, Da ; Dong, Gang
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2019-09, Vol.10 (10), p.701-16, Article 701
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An immune indicator based on BTK and DPEP2 identifies hot and cold tumors and clinical treatment outcomes in lung adenocarcinoma
Author / Creator:Han, Tao ; Liu, Yafeng ; Wu, Jing ; Bai, Ying ; Zhou, Jiawei ; Hu, Chunxiao ; Zhang, Wenting ; Guo, Jianqiang ; Wang, Qingsen ; Hu, Dong
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2023-03, Vol.13 (1), p.5153-5153, Article 5153
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CNDP1 knockout in zebrafish alters the amino acid metabolism, restrains weight gain, but does not protect from diabetic complications
Author / Creator:Schmöhl, Felix ; Peters, Verena ; Schmitt, Claus Peter ; Poschet, Gernot ; Büttner, Michael ; Li, Xiaogang ; Weigand, Tim ; Poth, Tanja ; Volk, Nadine ; Morgenstern, Jakob ; Fleming, Thomas ; Nawroth, Peter P. ; Kroll, Jens
Publisher:Cham: Springer International Publishing
Journal title:Cellular and molecular life sciences : CMLS, 2019-11, Vol.76 (22), p.4551-4568
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Prolidase Stimulates Proliferation and Migration through Activation of the PI3K/Akt/mTOR Signaling Pathway in Human Keratinocytes
Author / Creator:Misiura, Magdalena ; Baszanowska, Weronika ; Ościłowska, Ilona ; Pałka, Jerzy ; Miltyk, Wojciech
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-12, Vol.21 (23), p.9243
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DPP8 is a novel therapeutic target for multiple myeloma
Author / Creator:Sato, Tsutomu ; Tatekoshi, Ayumi ; Takada, Kohichi ; Iyama, Satoshi ; Kamihara, Yusuke ; Jawaid, Paras ; Rehman, Mati Ur ; Noguchi, Kyo ; Kondo, Takashi ; Kajikawa, Sayaka ; Arita, Kotaro ; Wada, Akinori ; Murakami, Jun ; Arai, Miho ; Yasuda, Ichiro ; Dang, Nam H. ; Hatano, Ryo ; Iwao, Noriaki ; Ohnuma, Kei ; Morimoto, Chikao
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-12, Vol.9 (1), p.18094-8, Article 18094
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Evaluation of prolidase activity and oxidative status in patients with knee osteoarthritis: relationships with radiographic severity and clinical parameters
Author / Creator:Altay, Mehmet Akif ; Ertürk, Cemil ; Bilge, Ali ; Yaptı, Metin ; Levent, Ali ; Aksoy, Nurten
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Rheumatology international, 2015-10, Vol.35 (10), p.1725-1731
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Showing 1 to 20 of 138 results

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Current Understanding of the Emerging Role of Prolidase in Cellular Metabolism

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DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis

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Aminopeptidases trim Xaa-Pro proteins, initiating their degradation by the Pro/N-degron pathway

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A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis

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N-lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids

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State of the Art in the Development of Human Serum Carnosinase Inhibitors

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DPP8/9 inhibitors activate the CARD8 inflammasome in resting lymphocytes

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Sulphostin-inspired N-phosphonopiperidones as selective covalent DPP8 and DPP9 inhibitors

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CNDP1 Overexpression by Promoter Hypomethylation Predicts Poor Prognosis and Immunotherapy Response in Mucosal Melanoma

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Exploring Secondary Amine Carnosine Derivatives: Design, Synthesis, and Properties

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Erythrocytes Prevent Degradation of Carnosine by Human Serum Carnosinase

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Carnosine Attenuates the Development of both Type 2 Diabetes and Diabetic Nephropathy in BTBR ob/ob Mice

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Multiplex gene knockout raises Ala-Gln production by Escherichia coli expressing amino acid ester acyltransferase

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GroEL actively stimulates folding of the endogenous substrate protein PepQ

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DPEP1 is a direct target of miR-193a-5p and promotes hepatoblastoma progression by PI3K/Akt/mTOR pathway

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An immune indicator based on BTK and DPEP2 identifies hot and cold tumors and clinical treatment outcomes in lung adenocarcinoma

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CNDP1 knockout in zebrafish alters the amino acid metabolism, restrains weight gain, but does not protect from diabetic complications

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Prolidase Stimulates Proliferation and Migration through Activation of the PI3K/Akt/mTOR Signaling Pathway in Human Keratinocytes

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DPP8 is a novel therapeutic target for multiple myeloma

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Evaluation of prolidase activity and oxidative status in patients with knee osteoarthritis: relationships with radiographic severity and clinical parameters

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