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Sub-series 1: Angus & Robertson book reviews in bound volumes, 1894-1970

Sub-series 2: Angus & Robertson book reviews, loose, 1957-1972

• Fungal phytopathogens can suppress plant immune mechanisms in order to colonize living host cells. Identifying all the molecular components involved is critical for elaborating a detailed systems-level model of plant infection probing pathogen weaknesses; yet, the hierarchy of molecular events controlling fungal responses to the plant cell is not clear.
• Here we show how, in the blast fungus Magnaporthe oryzae, terminating rice innate immunity requires a dynamic network of redox-responsive E3 ubiquitin ligases targeting fungal sirtuin 2 (Sir2), an antioxidation regulator required for suppressing the host oxidative burst.
• Immunoblotting, immunopurification, mass spectrometry and gene functional analyses showed that Sir2 levels responded to oxidative stress via a mechanism involving ubiquitination and three antagonistic E3 ubiquitin ligases: Grr1 and Ptr1 maintained basal Sir2 levels in the absence of oxidative stress; Upl3 facilitated Sir2 accumulation in response to oxidative stress. Grr1 and Upl3 interacted directly with Sir2 in a manner that decreased and scaled with oxidative stress, respectively.
• Deleting UPL3 depleted Sir2 during growth in rice cells, triggering host immunity and preventing infection. Overexpressing SIR2 in the Δupl3 mutant remediated pathogenicity. Our work reveals how redox-responsive E3 ubiquitin ligases in M. oryzae mediate Sir2 accumulation-dependent antioxidation to modulate plant innate immunity and host susceptibility.

The New phytologist, 2020-04, Vol.226 (2), p.523-540

Terminating rice innate immunity induction requires a network of antagonistic and redox-responsive E3 ubiquitin ligases targeting a fungal sirtuin

The Board of Registration in Medicine suspended Nadolny's license, alleging he failed to diagnose patients with a debilitating medical condition as required by law and delegated to nurse practitioners the authority to make such diagnoses.

Boston Globe (Online), 2016-06-02

Marijuana patients in limbo as doctor's license is suspended

The purpose of the correlational study was to explore the relationship between (a) supervisory leadership practice usage and inbound call center agent organizational commitment, (b) demographic variables and organizational commitment, and (c) organizational commitment and turnover intentions. The research leveraged (a) Kouzes and Posner’s leadership practices, (b) Meyer and Allen’s three-component commitment model, and (c) questions sourced to the Michigan Organizational Assessment Questionnaire. The findings indicated that supervisory leadership practice usage and agents’ affective and normative commitment are positively related and agents’ affective, normative, and continuance commitment are negatively related to turnover intention. Job and organizational tenure are not significantly related to organizational commitment. The study is the first known research to relate these variables among inbound agents in a U.S.-based call center organization.

Leadership practices, organizational commitment, and turnover intentions: A correlational study in a call center

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Sub-series 1: Angus & Robertson book reviews in bound volumes, 1894-1970

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Sub-series 2: Angus & Robertson book reviews, loose, 1957-1972

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Terminating rice innate immunity induction requires a network of antagonistic and redox-responsive E3 ubiquitin ligases targeting a fungal sirtuin

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Marijuana patients in limbo as doctor's license is suspended

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Leadership practices, organizational commitment, and turnover intentions: A correlational study in a call center

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