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1,977 results for Endoplasmic+Reticulum+Stress+-+drug+effects

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Pharmacological targeting of endoplasmic reticulum stress in disease
Author / Creator:Marciniak, Stefan J. ; Chambers, Joseph E. ; Ron, David
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Drug discovery, 2022-02, Vol.21 (2), p.115-140
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Molecular mechanisms of ferroptosis and its role in cancer therapy
Author / Creator:Xu, Tao ; Ding, Wei ; Ji, Xiaoyu ; Ao, Xiang ; Liu, Ying ; Yu, Wanpeng ; Wang, Jianxun
Publisher:England: John Wiley & Sons, Inc
Journal title:Journal of cellular and molecular medicine, 2019-08, Vol.23 (8), p.4900-4912
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Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma
Author / Creator:Hu, Kewen ; Li, Kun ; Lv, Jing ; Feng, Jie ; Chen, Jing ; Wu, Haigang ; Cheng, Feixiong ; Jiang, Wenhao ; Wang, Jieqiong ; Pei, Haixiang ; Chiao, Paul J. ; Cai, Zhenyu ; Chen, Yihua ; Liu, Mingyao ; Pang, Xiufeng
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2020-04, Vol.130 (4), p.1752-1766
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Targeting the unfolded protein response in disease
Author / Creator:Hetz, Claudio ; Chevet, Eric ; Harding, Heather P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Drug discovery, 2013-09, Vol.12 (9), p.703-719
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Pharmacological targeting of the unfolded protein response for disease intervention
Author / Creator:Hetz, Claudio ; Axten, Jeffrey M. ; Patterson, John B.
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2019-08, Vol.15 (8), p.764-775
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Empagliflozin Attenuates Non-Alcoholic Fatty Liver Disease (NAFLD) in High Fat Diet Fed ApoE(-/-) Mice by Activating Autophagy and Reducing ER Stress and Apoptosis
Author / Creator:Nasiri-Ansari, Narjes ; Nikolopoulou, Chrysa ; Papoutsi, Katerina ; Kyrou, Ioannis ; Mantzoros, Christos S. ; Kyriakopoulos, Georgios ; Chatzigeorgiou, Antonios ; Kalotychou, Vassiliki ; Randeva, Manpal S. ; Chatha, Kamaljit ; Kontzoglou, Konstantinos ; Kaltsas, Gregory ; Papavassiliou, Athanasios G. ; Randeva, Harpal S. ; Kassi, Eva
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2021-01, Vol.22 (2), p.818
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Role of Autophagy and Apoptosis in Non-Small-Cell Lung Cancer
Author / Creator:Liu, Guangbo ; Pei, Fen ; Yang, Fengqing ; Li, Lingxiao ; Amin, Amit ; Liu, Songnian ; Buchan, J. ; Cho, William
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2017-02, Vol.18 (2), p.367-367
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NOD1 and NOD2 signalling links ER stress with inflammation
Author / Creator:Keestra-Gounder, A. Marijke ; Byndloss, Mariana X. ; Seyffert, Núbia ; Young, Briana M. ; Chávez-Arroyo, Alfredo ; Tsai, April Y. ; Cevallos, Stephanie A. ; Winter, Maria G. ; Pham, Oanh H. ; Tiffany, Connor R. ; de Jong, Maarten F. ; Kerrinnes, Tobias ; Ravindran, Resmi ; Luciw, Paul A. ; McSorley, Stephen J. ; Bäumler, Andreas J. ; Tsolis, Renée M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-04, Vol.532 (7599), p.394-397
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Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit
Author / Creator:Das, Indrajit ; Krzyzosiak, Agnieszka ; Schneider, Kim ; Wrabetz, Lawrence ; D'Antonio, Maurizio ; Barry, Nicholas ; Sigurdardottir, Anna ; Bertolotti, Anne
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2015-04, Vol.348 (6231), p.239-242
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Lipophagy mediated carbohydrate-induced changes of lipid metabolism via oxidative stress, endoplasmic reticulum (ER) stress and ChREBP/PPARγ pathways
Author / Creator:Zhao, Tao ; Wu, Kun ; Hogstrand, Christer ; Xu, Yi-Huan ; Chen, Guang-Hui ; Wei, Chuan-Chuan ; Luo, Zhi
Publisher:Cham: Springer International Publishing
Journal title:Cellular and molecular life sciences : CMLS, 2020-05, Vol.77 (10), p.1987-2003
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Targeting ER stress–induced autophagy overcomes BRAF inhibitor resistance in melanoma
Author / Creator:Ma, Xiao-Hong ; Piao, Sheng-Fu ; Dey, Souvik ; Mcafee, Quentin ; Karakousis, Giorgos ; Villanueva, Jessie ; Hart, Lori S. ; Levi, Samuel ; Hu, Janice ; Zhang, Gao ; Lazova, Rossitza ; Klump, Vincent ; Pawelek, John M. ; Xu, Xiaowei ; Xu, Wei ; Schuchter, Lynn M. ; Davies, Michael A. ; Herlyn, Meenhard ; Winkler, Jeffrey ; Koumenis, Constantinos ; Amaravadi, Ravi K.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2014-03, Vol.124 (3), p.1406-1417
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Identification and Rescue of α-Synuclein Toxicity in Parkinson Patient-Derived Neurons
Author / Creator:Chung, Chee Yeun ; Khurana, Vikram ; Auluck, Pavan K. ; Tardiff, Daniel F. ; Mazzulli, Joseph R. ; Söldner, Frank ; Baru, Valeriya ; Lou, Yali ; Freyzon, Yelena ; Cho, Sukhee ; Mungenast, Alison E. ; Muffat, Julien ; Mitalipova, Maisam ; Pluth, Michael D. ; Jui, Nathan T. ; Schüle, Birgitt ; Lippard, Stephen J. ; Tsai, Li-Huei ; Krainc, Dimitri ; Buchwald, Stephen L. ; Jaenisch, Rudolf ; Lindquist, Susan
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2013-11, Vol.342 (6161), p.983-987
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Kaempferol induces autophagic cell death via IRE1-JNK-CHOP pathway and inhibition of G9a in gastric cancer cells
Author / Creator:Kim, Tae Woo ; Lee, Seon Young ; Kim, Mia ; Cheon, Chunhoo ; Ko, Seong-Gyu
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2018-08, Vol.9 (9), p.875-14, Article 875
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Thapsigargin—From Traditional Medicine to Anticancer Drug
Author / Creator:Jaskulska, Agata ; Janecka, Anna Ewa ; Gach-Janczak, Katarzyna
Publisher:Switzerland: MDPI
Journal title:International journal of molecular sciences, 2020-12, Vol.22 (1), p.4
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Tunicamycin specifically aggravates ER stress and overcomes chemoresistance in multidrug-resistant gastric cancer cells by inhibiting N-glycosylation
Author / Creator:Wu, Jian ; Chen, Sheng ; Liu, Hao ; Zhang, Zhe ; Ni, Zhen ; Chen, Jie ; Yang, Zhiping ; Nie, Yongzhan ; Fan, Daiming
Publisher:England: BioMed Central Ltd
Journal title:Journal of experimental & clinical cancer research, 2018-11, Vol.37 (1), p.272-272, Article 272
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Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis
Author / Creator:Dixon, Scott J ; Patel, Darpan N ; Welsch, Matthew ; Skouta, Rachid ; Lee, Eric D ; Hayano, Miki ; Thomas, Ajit G ; Gleason, Caroline E ; Tatonetti, Nicholas P ; Slusher, Barbara S ; Stockwell, Brent R
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2014-05, Vol.3, p.e02523
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ArticlesPeer ReviewedFull Text
Attenuation of Lipopolysaccharide-Induced Acute Lung Injury by Hispolon in Mice, Through Regulating the TLR4/PI3K/Akt/mTOR and Keap1/Nrf2/HO-1 Pathways, and Suppressing Oxidative Stress-Mediated ER St...
Author / Creator:Huang, Ching-Ying ; Deng, Jeng-Shyan ; Huang, Wen-Chin ; Jiang, Wen-Ping ; Huang, Guan-Jhong
Publisher:Switzerland: MDPI AG
Journal title:Nutrients, 2020-06, Vol.12 (6), p.1742
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PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress
Author / Creator:Verfaillie, T ; Rubio, N ; Garg, A D ; Bultynck, G ; Rizzuto, R ; Decuypere, J-P ; Piette, J ; Linehan, C ; Gupta, S ; Samali, A ; Agostinis, P
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2012-11, Vol.19 (11), p.1880-1891
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Activation of the hypothalamic–pituitary–adrenal axis by exogenous and endogenous GDF15
Author / Creator:Cimino, Irene ; Kim, Hanna ; Tung, Y. C. Loraine ; Pedersen, Kent ; Rimmington, Debra ; Tadross, John A. ; Kohnke, Sara N. ; Neves-Costa, Ana ; Barros, André ; Joaquim, Stephanie ; Bennett, Don ; Melvin, Audrey ; Lockhart, Samuel M. ; Rostron, Anthony J. ; Scott, Jonathan ; Liu, Hui ; Burling, Keith ; Barker, Peter ; Clatworthy, Menna R. ; Lee, E-Chiang ; Simpson, A. John ; Yeo, Giles S. H. ; Moita, Luís F. ; Bence, Kendra K. ; Jørgensen, Sebastian Beck ; Coll, Anthony P. ; Breen, Danna M. ; O’Rahilly, Stephen
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-07, Vol.118 (27), p.1-10
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Multimodal immunogenic cancer cell death as a consequence of anticancer cytotoxic treatments
Author / Creator:Inoue, H ; Tani, K
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2014-01, Vol.21 (1), p.39-49
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Showing 1 to 20 of 1,977 results

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Pharmacological targeting of endoplasmic reticulum stress in disease

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Molecular mechanisms of ferroptosis and its role in cancer therapy

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Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma

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Targeting the unfolded protein response in disease

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Pharmacological targeting of the unfolded protein response for disease intervention

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Empagliflozin Attenuates Non-Alcoholic Fatty Liver Disease (NAFLD) in High Fat Diet Fed ApoE(-/-) Mice by Activating Autophagy and Reducing ER Stress and Apoptosis

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Role of Autophagy and Apoptosis in Non-Small-Cell Lung Cancer

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NOD1 and NOD2 signalling links ER stress with inflammation

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Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit

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Lipophagy mediated carbohydrate-induced changes of lipid metabolism via oxidative stress, endoplasmic reticulum (ER) stress and ChREBP/PPARγ pathways

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Targeting ER stress–induced autophagy overcomes BRAF inhibitor resistance in melanoma

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Identification and Rescue of α-Synuclein Toxicity in Parkinson Patient-Derived Neurons

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Kaempferol induces autophagic cell death via IRE1-JNK-CHOP pathway and inhibition of G9a in gastric cancer cells

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Thapsigargin—From Traditional Medicine to Anticancer Drug

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Tunicamycin specifically aggravates ER stress and overcomes chemoresistance in multidrug-resistant gastric cancer cells by inhibiting N-glycosylation

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Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis

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Attenuation of Lipopolysaccharide-Induced Acute Lung Injury by Hispolon in Mice, Through Regulating the TLR4/PI3K/Akt/mTOR and Keap1/Nrf2/HO-1 Pathways, and Suppressing Oxidative Stress-Mediated ER St...

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PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress

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Activation of the hypothalamic–pituitary–adrenal axis by exogenous and endogenous GDF15

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Multimodal immunogenic cancer cell death as a consequence of anticancer cytotoxic treatments

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