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ArticlesPeer ReviewedFull Text
A guanidine-based coronavirus replication inhibitor which targets the nsp15 endoribonuclease and selects for interferon-susceptible mutant viruses
Author / Creator:Van Loy, Benjamin ; Pujol, Eugènia ; Kamata, Kenichi ; Lee, Xiao Yin ; Bakirtzoglou, Nikolai ; Van Berwaer, Ria ; Vandeput, Julie ; Mestdagh, Cato ; Persoons, Leentje ; De Wijngaert, Brent ; Goovaerts, Quinten ; Noppen, Sam ; Jacquemyn, Maarten ; Ahmadzadeh, Kourosh ; Bernaerts, Eline ; Martín-López, Juan ; Escriche, Celia ; Vanmechelen, Bert ; Krasniqi, Besir ; Singh, Abhimanyu K. ; Daelemans, Dirk ; Maes, Piet ; Matthys, Patrick ; Dehaen, Wim ; Rozenski, Jef ; Das, Kalyan ; Voet, Arnout ; Vázquez, Santiago ; Naesens, Lieve ; Stevaert, Annelies
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2025-02, Vol.21 (2), p.e1012571
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ArticlesFull Text
A guanidine-based coronavirus replication inhibitor which targets the nsp15 endoribonuclease and selects for interferon-susceptible mutant viruses
Author / Creator:Benjamin Van Loy ; Pujol, Eugenia ; Kamata, Kenichi ; Xiao Yin Lee ; Bakirtzoglou, Nikolai ; Ria Van Berwaer ; Vandeput, Julie ; Cato Mestdagh ; Persoons, Leentje ; De Wijngaert, Brent ; Goovaerts, Quinten ; Noppen, Sam ; Jacquemyn, Maarten ; Ahmadzadeh, Kourosh ; Bernaerts, Eline ; Martín-López, Juan ; Escriche, Celia ; Vanmechelen, Bert ; Krasniqi, Besir ; Singh, Abhimanyu K ; Daelemans, Dirk ; Maes, Piet ; Matthys, Patrick ; Dehaen, Wim ; Rozenski, Jef ; Das, Kalyan ; Voet, Arnout ; Vazquez, Santiago ; Naesens, Lieve Mj ; Stevaert, Annelies
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2025-01
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A guanidine-based coronavirus replication inhibitor which targets the nsp15 endoribonuclease and selects for interferon-susceptible mutant viruses

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A guanidine-based coronavirus replication inhibitor which targets the nsp15 endoribonuclease and selects for interferon-susceptible mutant viruses

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