A guanidine-based coronavirus replication inhibitor which targets the nsp15 endoribonuclease and sel...
A guanidine-based coronavirus replication inhibitor which targets the nsp15 endoribonuclease and selects for interferon-susceptible mutant viruses
About this item
Full title
Author / Creator
Van Loy, Benjamin , Pujol, Eugènia , Kamata, Kenichi , Lee, Xiao Yin , Bakirtzoglou, Nikolai , Van Berwaer, Ria , Vandeput, Julie , Mestdagh, Cato , Persoons, Leentje , De Wijngaert, Brent , Goovaerts, Quinten , Noppen, Sam , Jacquemyn, Maarten , Ahmadzadeh, Kourosh , Bernaerts, Eline , Martín-López, Juan , Escriche, Celia , Vanmechelen, Bert , Krasniqi, Besir , Singh, Abhimanyu K. , Daelemans, Dirk , Maes, Piet , Matthys, Patrick , Dehaen, Wim , Rozenski, Jef , Das, Kalyan , Voet, Arnout , Vázquez, Santiago , Naesens, Lieve and Stevaert, Annelies
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
The approval of COVID-19 vaccines and antiviral drugs has been crucial to end the global health crisis caused by SARS-CoV-2. However, to prepare for future outbreaks from drug-resistant variants and novel zoonotic coronaviruses (CoVs), additional therapeutics with a distinct antiviral mechanism are needed. Here, we report a novel guanidine-substitu...
Alternative Titles
Full title
A guanidine-based coronavirus replication inhibitor which targets the nsp15 endoribonuclease and selects for interferon-susceptible mutant viruses
Authors, Artists and Contributors
Author / Creator
Pujol, Eugènia
Kamata, Kenichi
Lee, Xiao Yin
Bakirtzoglou, Nikolai
Van Berwaer, Ria
Vandeput, Julie
Mestdagh, Cato
Persoons, Leentje
De Wijngaert, Brent
Goovaerts, Quinten
Noppen, Sam
Jacquemyn, Maarten
Ahmadzadeh, Kourosh
Bernaerts, Eline
Martín-López, Juan
Escriche, Celia
Vanmechelen, Bert
Krasniqi, Besir
Singh, Abhimanyu K.
Daelemans, Dirk
Maes, Piet
Matthys, Patrick
Dehaen, Wim
Rozenski, Jef
Das, Kalyan
Voet, Arnout
Vázquez, Santiago
Naesens, Lieve
Stevaert, Annelies
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a216dbea8b86427aac77438cd5a3264a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a216dbea8b86427aac77438cd5a3264a
Other Identifiers
ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1012571
