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A phase I/II minor histocompatibility antigen-loaded dendritic cell vaccination trial to safely improve the efficacy of donor lymphocyte infusions in myeloma
Author / Creator:Franssen, L E ; Roeven, M W H ; Hobo, W ; Doorn, R ; Oostvogels, R ; Falkenburg, J H F ; van de Donk, N W ; Kester, M G D ; Fredrix, H ; Westinga, K ; Slaper-Cortenbach, I ; Spierings, E ; Kersten, M J ; Dolstra, H ; Mutis, T ; Schaap, N ; Lokhorst, H M
Publisher:London: Nature Publishing Group UK
Journal title:Bone marrow transplantation (Basingstoke), 2017-10, Vol.52 (10), p.1378-1383
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Myeloablative T cell-depleted alloSCT with early sequential prophylactic donor lymphocyte infusion is an efficient and safe post-remission treatment for adult ALL
Author / Creator:Eefting, M ; Halkes, C J M ; de Wreede, L C ; van Pelt, C M ; Kersting, S ; Marijt, E W A ; von dem Borne, P A ; Willemze, R ; Veelken, H ; Falkenburg, J H F
Publisher:London: Nature Publishing Group UK
Journal title:Bone marrow transplantation (Basingstoke), 2014-02, Vol.49 (2), p.287-291
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Indications for allo- and auto-SCT for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2015
Author / Creator:Sureda, A ; Bader, P ; Cesaro, S ; Dreger, P ; Duarte, R F ; Dufour, C ; Falkenburg, J H F ; Farge-Bancel, D ; Gennery, A ; Kröger, N ; Lanza, F ; Marsh, J C ; Nagler, A ; Peters, C ; Velardi, A ; Mohty, M ; Madrigal, A
Publisher:London: Nature Publishing Group UK
Journal title:Bone marrow transplantation (Basingstoke), 2015-08, Vol.50 (8), p.1037-1056
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Bone marrow central memory and memory stem T-cell exhaustion in AML patients relapsing after HSCT
Author / Creator:Noviello, Maddalena ; Manfredi, Francesco ; Ruggiero, Eliana ; Perini, Tommaso ; Oliveira, Giacomo ; Cortesi, Filippo ; De Simone, Pantaleo ; Toffalori, Cristina ; Gambacorta, Valentina ; Greco, Raffaella ; Peccatori, Jacopo ; Casucci, Monica ; Casorati, Giulia ; Dellabona, Paolo ; Onozawa, Masahiro ; Teshima, Takanori ; Griffioen, Marieke ; Halkes, Constantijn J. M. ; Falkenburg, J. H. F. ; Stölzel, Friedrich ; Altmann, Heidi ; Bornhäuser, Martin ; Waterhouse, Miguel ; Zeiser, Robert ; Finke, Jürgen ; Cieri, Nicoletta ; Bondanza, Attilio ; Vago, Luca ; Ciceri, Fabio ; Bonini, Chiara
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-03, Vol.10 (1), p.1065-1065, Article 1065
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Microarray Gene Expression Analysis to Evaluate Cell Type Specific Expression of Targets Relevant for Immunotherapy of Hematological Malignancies
Author / Creator:Pont, M J ; Honders, M W ; Kremer, A N ; van Kooten, C ; Out, C ; Hiemstra, P S ; de Boer, H C ; Jager, M J ; Schmelzer, E ; Vries, R G ; Al Hinai, A S ; Kroes, W G ; Monajemi, R ; Goeman, J J ; Böhringer, S ; Marijt, W A F ; Falkenburg, J H F ; Griffioen, M
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-05, Vol.11 (5), p.e0155165-e0155165
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Hematopoietic SCT in Europe 2013: recent trends in the use of alternative donors showing more haploidentical donors but fewer cord blood transplants
Author / Creator:Passweg, J R ; Baldomero, H ; Bader, P ; Bonini, C ; Cesaro, S ; Dreger, P ; Duarte, R F ; Dufour, C ; Falkenburg, J H F ; Farge-Bancel, D ; Gennery, A ; Kröger, N ; Lanza, F ; Nagler, A ; Sureda, A ; Mohty, M
Publisher:London: Nature Publishing Group UK
Journal title:Bone marrow transplantation (Basingstoke), 2015-04, Vol.50 (4), p.476-482
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Hematopoietic SCT in Europe: data and trends in 2012 with special consideration of pediatric transplantation
Author / Creator:Passweg, J R ; Baldomero, H ; Peters, C ; Gaspar, H B ; Cesaro, S ; Dreger, P ; Duarte, R F ; Falkenburg, J H F ; Farge-Bancel, D ; Gennery, A ; Halter, J ; Kröger, N ; Lanza, F ; Marsh, J ; Mohty, M ; Sureda, A ; Velardi, A ; Madrigal, A
Publisher:London: Nature Publishing Group UK
Journal title:Bone marrow transplantation (Basingstoke), 2014-06, Vol.49 (6), p.744-750
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HLA-DP as specific target for cellular immunotherapy in HLA class II-expressing B-cell leukemia
Author / Creator:Rutten, C E ; van Luxemburg-Heijs, S A P ; Griffioen, M ; Marijt, E W A ; Jedema, I ; Heemskerk, M H M ; Posthuma, E F M ; Willemze, R ; Falkenburg, J H F
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2008-07, Vol.22 (7), p.1387-1394
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Hematopoietic SCT in Europe: data and trends in 2011
Author / Creator:Passweg, J R ; Baldomero, H ; Bregni, M ; Cesaro, S ; Dreger, P ; Duarte, R F ; Falkenburg, J H F ; Kröger, N ; Farge-Bancel, D ; Bobby Gaspar, H ; Marsh, J ; Mohty, M ; Peters, C ; Sureda, A ; Velardi, A ; Ruiz de Elvira, C ; Madrigal, A
Publisher:London: Nature Publishing Group UK
Journal title:Bone marrow transplantation (Basingstoke), 2013-09, Vol.48 (9), p.1161-1167
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Feasibility, safety, and efficacy of early prophylactic donor lymphocyte infusion after T cell-depleted allogeneic stem cell transplantation in acute leukemia patients
Author / Creator:van der Zouwen, Boris ; Koster, E. A. S. ; von dem Borne, P. A. ; Oosten, L. E. M. ; Roza-Scholten, M. W. I. ; Snijders, T. J. F. ; van Lammeren, D. ; van Balen, P. ; Marijt, W. A. F. ; Veelken, H. ; Falkenburg, J. H. F. ; de Wreede, L. C. ; Halkes, C. J. M.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Annals of hematology, 2023-05, Vol.102 (5), p.1203-1213
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Donor T-cell responses and disease progression patterns of multiple myeloma
Author / Creator:Eefting, M ; de Wreede, L C ; Von dem Borne, P A ; Halkes, C J M ; Kersting, S ; Marijt, E W A ; Putter, H ; Veelken, H ; Schetelig, J ; Falkenburg, J H F
Publisher:London: Nature Publishing Group UK
Journal title:Bone marrow transplantation (Basingstoke), 2017-12, Vol.52 (12), p.1609-1615
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Molecular persistence of chronic myeloid leukemia caused by donor T cells specific for lineage-restricted maturation antigens not recognizing immature progenitor-cells
Author / Creator:VON DEM BORNE, P. A ; VAN LUXEMBURG-HEIJS, S. A. P ; HEEMSKERK, M. H. M ; JEDEMA, I ; MULDER, A ; WILLEMZE, R ; FALKENBURG, J. H. F
Publisher:London: Nature Publishing
Journal title:Leukemia, 2006-06, Vol.20 (6), p.1040-1046
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Human allo-reactive CD4+ T cells as strong mediators of anti-tumor immunity in NOD/scid mice engrafted with human acute lymphoblastic leukemia
Author / Creator:Stevanović, S ; Griffioen, M ; Nijmeijer, B A ; van Schie, M L J ; Stumpf, A N ; Rutten, C E ; Willemze, R ; Falkenburg, J H F
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2012-02, Vol.26 (2), p.312-322
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Multi-cistronic vector encoding optimized safety switch for adoptive therapy with T-cell receptor-modified T cells
Author / Creator:van Loenen, M M ; de Boer, R ; Hagedoorn, R S ; Jankipersadsing, V ; Amir, A L ; Falkenburg, J H F ; Heemskerk, M H M
Publisher:London: Nature Publishing Group UK
Journal title:Gene therapy, 2013-08, Vol.20 (8), p.861-867
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Internalization and cell cycle-dependent killing of leukemic cells by Gemtuzumab Ozogamicin: rationale for efficacy in CD33-negative malignancies with endocytic capacity
Author / Creator:Jedema, I ; Barge, R M Y ; van der Velden, V H J ; Nijmeijer, B A ; van Dongen, J J M ; Willemze, R ; Falkenburg, J H F
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2004-02, Vol.18 (2), p.316-325
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Chromosomal aberrations in leukaemia cells may delete tumour target antigens of stem cell-based immunotherapy
Author / Creator:Hambach, L ; Nijmeijer, B A ; Drabbels, J J M ; Falkenburg, J H F ; Goulmy, Els
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2006-07, Vol.20 (7), p.1298-1300
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Long-term follow-up of myeloablative allogeneic stem cell transplantation using Campath 'in the bag' as T-cell depletion : the Leiden experience
Author / Creator:BARGE, R. M. Y ; STARRENBURG, C. W. J ; FALKENBURG, J. H. F ; FIBBE, W. E ; MARIJT, E. W ; WILLEMZE, R
Publisher:Basingstoke: Nature Publishing Group
Journal title:Bone marrow transplantation (Basingstoke), 2006-06, Vol.37 (12), p.1129-1134
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Human cytotoxic T lymphocytes specific for a single minor histocompatibility antigen HA-1 are effective against human lymphoblastic leukaemia in NOD/scid mice
Author / Creator:Hambach, L ; Nijmeijer, B A ; Aghai, Z ; Schie, M L J van ; Wauben, M H M ; Falkenburg, J H F ; Goulmy, E
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2006-02, Vol.20 (2), p.371-374
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ArticlesPeer ReviewedFull Text
Allo-reactive T cells for the treatment of hematological malignancies
Author / Creator:Falkenburg, J.H.F. ; Jedema, I.
Publisher:United States: Elsevier B.V
Journal title:Molecular oncology, 2015-12, Vol.9 (10), p.1894-1903
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Direct cloning of leukemia-reactive T cells from patients treated with donor lymphocyte infusion shows a relative dominance of hematopoiesis-restricted minor histocompatibility antigen HA-1 and HA-2 s...
Author / Creator:Kloosterboer, F M ; van Luxemburg-Heijs, S A P ; Soest, RA van ; Barbui, A M ; Egmond, HM van ; Strijbosch, M P W ; Kester, M G D ; Marijt, W A F ; Goulmy, E ; Willemze, R ; Falkenburg, J H F
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2004-04, Vol.18 (4), p.798-808
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A phase I/II minor histocompatibility antigen-loaded dendritic cell vaccination trial to safely improve the efficacy of donor lymphocyte infusions in myeloma

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Myeloablative T cell-depleted alloSCT with early sequential prophylactic donor lymphocyte infusion is an efficient and safe post-remission treatment for adult ALL

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Indications for allo- and auto-SCT for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2015

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Bone marrow central memory and memory stem T-cell exhaustion in AML patients relapsing after HSCT

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Microarray Gene Expression Analysis to Evaluate Cell Type Specific Expression of Targets Relevant for Immunotherapy of Hematological Malignancies

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Hematopoietic SCT in Europe 2013: recent trends in the use of alternative donors showing more haploidentical donors but fewer cord blood transplants

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Hematopoietic SCT in Europe: data and trends in 2012 with special consideration of pediatric transplantation

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HLA-DP as specific target for cellular immunotherapy in HLA class II-expressing B-cell leukemia

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Hematopoietic SCT in Europe: data and trends in 2011

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Feasibility, safety, and efficacy of early prophylactic donor lymphocyte infusion after T cell-depleted allogeneic stem cell transplantation in acute leukemia patients

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Donor T-cell responses and disease progression patterns of multiple myeloma

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Molecular persistence of chronic myeloid leukemia caused by donor T cells specific for lineage-restricted maturation antigens not recognizing immature progenitor-cells

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Human allo-reactive CD4+ T cells as strong mediators of anti-tumor immunity in NOD/scid mice engrafted with human acute lymphoblastic leukemia

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Multi-cistronic vector encoding optimized safety switch for adoptive therapy with T-cell receptor-modified T cells

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Internalization and cell cycle-dependent killing of leukemic cells by Gemtuzumab Ozogamicin: rationale for efficacy in CD33-negative malignancies with endocytic capacity

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Chromosomal aberrations in leukaemia cells may delete tumour target antigens of stem cell-based immunotherapy

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Long-term follow-up of myeloablative allogeneic stem cell transplantation using Campath 'in the bag' as T-cell depletion : the Leiden experience

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Human cytotoxic T lymphocytes specific for a single minor histocompatibility antigen HA-1 are effective against human lymphoblastic leukaemia in NOD/scid mice

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Allo-reactive T cells for the treatment of hematological malignancies

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Direct cloning of leukemia-reactive T cells from patients treated with donor lymphocyte infusion shows a relative dominance of hematopoiesis-restricted minor histocompatibility antigen HA-1 and HA-2 s...

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