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Metabolomics for personalized medicine: the input of analytical chemistry from biomarker discovery to point-of-care tests
Author / Creator:Castelli, Florence Anne ; Rosati, Giulio ; Moguet, Christian ; Fuentes, Celia ; Marrugo-Ramírez, Jose ; Lefebvre, Thibaud ; Volland, Hervé ; Merkoçi, Arben ; Simon, Stéphanie ; Fenaille, François ; Junot, Christophe
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Analytical and bioanalytical chemistry, 2022-01, Vol.414 (2), p.759-789
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The effect of acute moderate-intensity exercise on the serum and fecal metabolomes and the gut microbiota of cross-country endurance athletes
Author / Creator:Tabone, Mariangela ; Bressa, Carlo ; García-Merino, Jose Angel ; Moreno-Pérez, Diego ; Van, Emeline Chu ; Castelli, Florence A. ; Fenaille, François ; Larrosa, Mar
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-02, Vol.11 (1), p.3558-3558, Article 3558
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High plasma level of S100A8/S100A9 and S100A12 at admission indicates a higher risk of death in septic shock patients
Author / Creator:Dubois, Christelle ; Marcé, Dominique ; Faivre, Valérie ; Lukaszewicz, Anne-Claire ; Junot, Christophe ; Fenaille, François ; Simon, Stéphanie ; Becher, François ; Morel, Nathalie ; Payen, Didier
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-10, Vol.9 (1), p.15660-7, Article 15660
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Gout and pseudo-gout-related crystals promote GLUT1-mediated glycolysis that governs NLRP3 and interleukin-1β activation on macrophages
Author / Creator:Renaudin, Felix ; Orliaguet, Lucie ; Castelli, Florence ; Fenaille, François ; Prignon, Aurelie ; Alzaid, Fawaz ; Combes, Christele ; Delvaux, Aurélie ; Adimy, Yasmina ; Cohen-Solal, Martine ; Richette, Pascal ; Bardin, Thomas ; Riveline, Jean-Pierre ; Venteclef, Nicolas ; Lioté, Frédéric ; Campillo-Gimenez, Laure ; Ea, Hang-Korng
Publisher:England: Elsevier Limited
Journal title:Annals of the rheumatic diseases, 2020-11, Vol.79 (11), p.1506-1514
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A European proposal for quality control and quality assurance of tandem mass spectral libraries
Author / Creator:Oberacher, Herbert ; Sasse, Michael ; Antignac, Jean-Philippe ; Guitton, Yann ; Debrauwer, Laurent ; Jamin, Emilien L. ; Schulze, Tobias ; Krauss, Martin ; Covaci, Adrian ; Caballero-Casero, Noelia ; Rousseau, Kathleen ; Damont, Annelaure ; Fenaille, François ; Lamoree, Marja ; Schymanski, Emma L.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Environmental sciences Europe, 2020-12, Vol.32 (1), Article 43
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Arginine-selective modulation of the lysosomal transporter PQLC2 through a gate-tuning mechanism
Author / Creator:Leray, Xavier ; Conti, Rossella ; Li, Yan ; Debacker, Cécile ; Castelli, Florence ; Fenaille, François ; Zdebik, Anselm A. ; Pusch, Michael ; Gasnier, Bruno
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-08, Vol.118 (32), p.1-10
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Red blood cell metabolomics identify ergothioneine as a key metabolite in DMARD-naïve rheumatoid arthritis and response to methotrexate
Author / Creator:Sigaux, Johanna ; Junot, Christophe ; Boissier, Marie-Christophe ; Petit, Mylène ; Breckler, Magali ; Castelli, Florence ; Fenaille, François ; Roméo, Paul-Henri ; Semerano, Luca
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-09, Vol.14 (1), p.21005-7, Article 21005
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Multiplex Detection of 24 Staphylococcal Enterotoxins in Culture Supernatant Using Liquid Chromatography Coupled to High-Resolution Mass Spectrometry
Author / Creator:Lefebvre, Donatien ; Blanco-Valle, Kevin ; Hennekinne, Jacques-Antoine ; Simon, Stéphanie ; Fenaille, François ; Becher, François ; Nia, Yacine
Publisher:Switzerland: MDPI AG
Journal title:Toxins, 2022-03, Vol.14 (4), p.249
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Comparative Evaluation of Data Dependent and Data Independent Acquisition Workflows Implemented on an Orbitrap Fusion for Untargeted Metabolomics
Author / Creator:Barbier Saint Hilaire, Pierre ; Rousseau, Kathleen ; Seyer, Alexandre ; Dechaumet, Sylvain ; Damont, Annelaure ; Junot, Christophe ; Fenaille, François
Publisher:Switzerland: MDPI AG
Journal title:Metabolites, 2020-04, Vol.10 (4), p.158-17
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Glutathione conjugates of the mercapturic acid pathway and guanine adduct as biomarkers of exposure to CEES, a sulfur mustard analog
Author / Creator:Roser, Marie ; Béal, David ; Eldin, Camille ; Gudimard, Leslie ; Caffin, Fanny ; Gros-Désormeaux, Fanny ; Léonço, Daniel ; Fenaille, François ; Junot, Christophe ; Piérard, Christophe ; Douki, Thierry
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Analytical and bioanalytical chemistry, 2021-02, Vol.413 (5), p.1337-1351
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Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia
Author / Creator:Pardieu, Bryann ; Pasanisi, Justine ; Ling, Frank ; Dal Bello, Reinaldo ; Penneroux, Justine ; Su, Angela ; Joudinaud, Romane ; Chat, Laureen ; Wu, Hsin Chieh ; Duchmann, Matthieu ; Sodaro, Gaetano ; Chauvel, Clémentine ; Castelli, Florence A. ; Vasseur, Loic ; Pacchiardi, Kim ; Belloucif, Yannis ; Laiguillon, Marie-Charlotte ; Meduri, Eshwar ; Vaganay, Camille ; Alexe, Gabriela ; Berrou, Jeannig ; Benaksas, Chaima ; Forget, Antoine ; Braun, Thorsten ; Gardin, Claude ; Raffoux, Emmanuel ; Clappier, Emmanuelle ; Adès, Lionel ; de Thé, Hugues ; Fenaille, François ; Huntly, Brian J. ; Stegmaier, Kimberly ; Dombret, Hervé ; Fenouille, Nina ; Lobry, Camille ; Puissant, Alexandre ; Itzykson, Raphael
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2022-06, Vol.36 (6), p.1585-1595
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ArticlesPeer ReviewedFull Text
Histone variant H2A.J accumulates in senescent cells and promotes inflammatory gene expression
Author / Creator:Contrepois, Kévin ; Coudereau, Clément ; Benayoun, Bérénice A. ; Schuler, Nadine ; Roux, Pierre-François ; Bischof, Oliver ; Courbeyrette, Régis ; Carvalho, Cyril ; Thuret, Jean-Yves ; Ma, Zhihai ; Derbois, Céline ; Nevers, Marie-Claire ; Volland, Hervé ; Redon, Christophe E. ; Bonner, William M. ; Deleuze, Jean-François ; Wiel, Clotilde ; Bernard, David ; Snyder, Michael P. ; Rübe, Claudia E. ; Olaso, Robert ; Fenaille, François ; Mann, Carl
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-05, Vol.8 (1), p.14995-18, Article 14995
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ArticlesPeer ReviewedFull Text
Using a multiomics approach to unravel a septic shock specific signature in skeletal muscle
Author / Creator:Duceau, Baptiste ; Blatzer, Michael ; Bardon, Jean ; Chaze, Thibault ; Giai Gianetto, Quentin ; Castelli, Florence ; Fenaille, François ; Duarte, Lucie ; Lescot, Thomas ; Tresallet, Christophe ; Riou, Bruno ; Matondo, Mariette ; Langeron, Olivier ; Rocheteau, Pierre ; Chrétien, Fabrice ; Bouglé, Adrien
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-11, Vol.12 (1), p.18776-18776, Article 18776
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Quantification of Staphylococcal Enterotoxin A Variants at Low Level in Dairy Products by High-Resolution Top-Down Mass Spectrometry
Author / Creator:Aveilla, Nina ; Feraudet-Tarisse, Cécile ; Marcé, Dominique ; Fatihi, Abdelhak ; Fenaille, François ; Hennekinne, Jacques-Antoine ; Simon, Stéphanie ; Nia, Yacine ; Becher, François
Publisher:Switzerland: MDPI AG
Journal title:Toxins, 2024-12, Vol.16 (12), p.535
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H2B Type 1-K Accumulates in Senescent Fibroblasts with Persistent DNA Damage along with Methylated and Phosphorylated Forms of HMGA1
Author / Creator:Contrepois, Kévin ; Mann, Carl ; Fenaille, François
Publisher:Basel: MDPI AG
Journal title:Proteomes, 2021-06, Vol.9 (2), p.30
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Mass Spectrometry for Neurobiomarker Discovery: The Relevance of Post-Translational Modifications
Author / Creator:Azevedo, Rita ; Jacquemin, Chloé ; Villain, Nicolas ; Fenaille, François ; Lamari, Foudil ; Becher, François
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2022-04, Vol.11 (8), p.1279
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Ricin Antibodies’ Neutralizing Capacity against Different Ricin Isoforms and Cultivars
Author / Creator:Orsini Delgado, Maria Lucia ; Avril, Arnaud ; Prigent, Julie ; Dano, Julie ; Rouaix, Audrey ; Worbs, Sylvia ; Dorner, Brigitte G. ; Rougeaux, Clémence ; Becher, François ; Fenaille, François ; Livet, Sandrine ; Volland, Hervé ; Tournier, Jean-Nicolas ; Simon, Stéphanie
Publisher:Switzerland: MDPI
Journal title:Toxins, 2021-01, Vol.13 (2), p.100
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Despite similar clinical features metabolomics reveals distinct signatures in insulin resistant and progressively obese minipigs
Author / Creator:Bousahba, Imene ; David, Jérémie ; Castelli, Florence ; Chollet, Céline ; Ouzia, Sadia ; Fenaille, François ; Rémond, Didier ; Poupin, Nathalie ; Polakof, Sergio
Publisher:Dordrecht: Springer Netherlands
Journal title:Journal of physiology and biochemistry, 2023-05, Vol.79 (2), p.397-413
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A multidrug ABC transporter with a taste for GTP
Author / Creator:Orelle, Cédric ; Durmort, Claire ; Mathieu, Khadija ; Duchêne, Benjamin ; Aros, Sandrine ; Fenaille, François ; André, François ; Junot, Christophe ; Vernet, Thierry ; Jault, Jean-Michel
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-02, Vol.8 (1), p.2309-14, Article 2309
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P10 Characterization of Metabolomic Fingerprints in Patients With Hepatic Encephalopathy and Fulminant Hepatitis or Acute Decompensation of Cirrhosis, Before and After Liver Transplantation
Author / Creator:Pinceaux, Kieran ; Castelli, Florence ; Fenaille, François ; Junot, Christophe ; Mouri, Sarah ; Coirier, Valentin ; Giguet, Baptiste ; Camus, Christophe ; Tadié, Jean-Marc ; Bardou-Jacquet, Édouard ; Houssel-Debry, Pauline ; Sulpice, Laurent ; Monsel, Antoine ; Sitbon, Alexandre ; Delmotte, Pierre-Romain ; Thabut, Dominique ; Weiss, Nicolas ; Rudler, Marika
Publisher:Philadelphia, PA: Wolters Kluwer
Journal title:The American journal of gastroenterology, 2023-09, Vol.118 (9S), p.S8-S9
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Metabolomics for personalized medicine: the input of analytical chemistry from biomarker discovery to point-of-care tests

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The effect of acute moderate-intensity exercise on the serum and fecal metabolomes and the gut microbiota of cross-country endurance athletes

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High plasma level of S100A8/S100A9 and S100A12 at admission indicates a higher risk of death in septic shock patients

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Gout and pseudo-gout-related crystals promote GLUT1-mediated glycolysis that governs NLRP3 and interleukin-1β activation on macrophages

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A European proposal for quality control and quality assurance of tandem mass spectral libraries

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Arginine-selective modulation of the lysosomal transporter PQLC2 through a gate-tuning mechanism

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Red blood cell metabolomics identify ergothioneine as a key metabolite in DMARD-naïve rheumatoid arthritis and response to methotrexate

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Multiplex Detection of 24 Staphylococcal Enterotoxins in Culture Supernatant Using Liquid Chromatography Coupled to High-Resolution Mass Spectrometry

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Comparative Evaluation of Data Dependent and Data Independent Acquisition Workflows Implemented on an Orbitrap Fusion for Untargeted Metabolomics

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Glutathione conjugates of the mercapturic acid pathway and guanine adduct as biomarkers of exposure to CEES, a sulfur mustard analog

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Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia

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Histone variant H2A.J accumulates in senescent cells and promotes inflammatory gene expression

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Using a multiomics approach to unravel a septic shock specific signature in skeletal muscle

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Quantification of Staphylococcal Enterotoxin A Variants at Low Level in Dairy Products by High-Resolution Top-Down Mass Spectrometry

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H2B Type 1-K Accumulates in Senescent Fibroblasts with Persistent DNA Damage along with Methylated and Phosphorylated Forms of HMGA1

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Mass Spectrometry for Neurobiomarker Discovery: The Relevance of Post-Translational Modifications

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Ricin Antibodies’ Neutralizing Capacity against Different Ricin Isoforms and Cultivars

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Despite similar clinical features metabolomics reveals distinct signatures in insulin resistant and progressively obese minipigs

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A multidrug ABC transporter with a taste for GTP

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P10 Characterization of Metabolomic Fingerprints in Patients With Hepatic Encephalopathy and Fulminant Hepatitis or Acute Decompensation of Cirrhosis, Before and After Liver Transplantation

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