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ArticlesPeer ReviewedFull Text
Structure of PINK1 in complex with its substrate ubiquitin
Author / Creator:Schubert, Alexander F. ; Gladkova, Christina ; Pardon, Els ; Wagstaff, Jane L. ; Freund, Stefan M. V. ; Steyaert, Jan ; Maslen, Sarah L. ; Komander, David
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-12, Vol.552 (7683), p.51-56
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Juxtaposition of Bub1 and Cdc20 on phosphorylated Mad1 during catalytic mitotic checkpoint complex assembly
Author / Creator:Fischer, Elyse S. ; Yu, Conny W. H. ; Hevler, Johannes F. ; McLaughlin, Stephen H. ; Maslen, Sarah L. ; Heck, Albert J. R. ; Freund, Stefan M. V. ; Barford, David
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-10, Vol.13 (1), p.6381-18, Article 6381
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TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control
Author / Creator:Douse, Christopher H. ; Tchasovnikarova, Iva A. ; Timms, Richard T. ; Protasio, Anna V. ; Seczynska, Marta ; Prigozhin, Daniil M. ; Albecka, Anna ; Wagstaff, Jane ; Williamson, James C. ; Freund, Stefan M. V. ; Lehner, Paul J. ; Modis, Yorgo
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-10, Vol.11 (1), p.4940-4940, Article 4940
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The native structure of the assembled matrix protein 1 of influenza A virus
Author / Creator:Peukes, Julia ; Xiong, Xiaoli ; Erlendsson, Simon ; Qu, Kun ; Wan, William ; Calder, Leslie J. ; Schraidt, Oliver ; Kummer, Susann ; Freund, Stefan M. V. ; Kräusslich, Hans-Georg ; Briggs, John A. G.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-11, Vol.587 (7834), p.495-498
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A Role for the ESCRT System in Cell Division in Archaea
Author / Creator:Samson, Rachel Y. ; Obita, Takayuki ; Freund, Stefan M. ; Williams, Roger L. ; Bell, Stephen D.
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2008-12, Vol.322 (5908), p.1710-1713
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FtsA forms actin-like protofilaments
Author / Creator:Szwedziak, Piotr ; Wang, Qing ; Freund, Stefan MV ; Löwe, Jan
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2012-05, Vol.31 (10), p.2249-2260
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ArticlesPeer ReviewedFull Text
Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne
Author / Creator:Bremm, Anja ; Freund, Stefan M V ; Komander, David
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2010-08, Vol.17 (8), p.939-947
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ArticlesPeer ReviewedFull Text
Regulation of Dishevelled DEP domain swapping by conserved phosphorylation sites
Author / Creator:Beitia, Gonzalo J. ; Rutherford, Trevor J. ; Freund, Stefan M. V. ; Pelham, Hugh R. ; Bienz, Mariann ; Gammons, Melissa V.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-06, Vol.118 (26), p.1-10
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Assembly, analysis and architecture of atypical ubiquitin chains
Author / Creator:Hospenthal, Manuela K ; Freund, Stefan M V ; Komander, David
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2013-05, Vol.20 (5), p.555-565
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HIV-1 capsid undergoes coupled binding and isomerization by the nuclear pore protein NUP358
Author / Creator:Bichel, Katsiaryna ; Price, Amanda J ; Schaller, Torsten ; Towers, Greg J ; Freund, Stefan MV ; James, Leo C
Publisher:England: BioMed Central Ltd
Journal title:Retrovirology, 2013-07, Vol.10 (1), p.81-81, Article 81
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Bacterial divisome protein FtsA forms curved antiparallel double filaments when binding to FtsN
Author / Creator:Nierhaus, Tim ; McLaughlin, Stephen H. ; Bürmann, Frank ; Kureisaite-Ciziene, Danguole ; Maslen, Sarah L. ; Skehel, J. Mark ; Yu, Conny W. H. ; Freund, Stefan M. V. ; Funke, Louise F. H. ; Chin, Jason W. ; Löwe, Jan
Publisher:London: Nature Publishing Group UK
Journal title:Nature microbiology, 2022-10, Vol.7 (10), p.1686-1701
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Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53
Author / Creator:Teufel, Daniel P ; Freund, Stefan M ; Bycroft, Mark ; Fersht, Alan R
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2007-04, Vol.104 (17), p.7009-7014
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Quaternary structures of tumor suppressor p53 and a specific p53-DNA complex
Author / Creator:Tidow, Henning ; Melero, Roberto ; Mylonas, Efstratios ; Freund, Stefan M.V ; Grossmann, J. Guenter ; Carazo, José María ; Svergun, Dmitri I ; Valle, Mikel ; Fersht, Alan R
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2007-07, Vol.104 (30), p.12324-12329
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ArticlesPeer ReviewedFull Text
Domain–domain interactions in full-length p53 and a specific DNA complex probed by methyl NMR spectroscopy
Author / Creator:Bista, Michal ; Freund, Stefan M ; Fersht, Alan R
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-09, Vol.109 (39), p.15752-15756
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ArticlesPeer ReviewedFull Text
Self-correcting mismatches during high-fidelity DNA replication
Author / Creator:Fernandez-Leiro, Rafael ; Conrad, Julian ; Yang, Ji-Chun ; Freund, Stefan M V ; Scheres, Sjors H W ; Lamers, Meindert H
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2017-02, Vol.24 (2), p.140-143
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SWI/SNF subunit BAF155 N-terminus structure informs the impact of cancer-associated mutations and reveals a potential drug binding site
Author / Creator:Allen, Mark D. ; Freund, Stefan M. V. ; Bycroft, Mark ; Zinzalla, Giovanna
Publisher:London: Nature Publishing Group UK
Journal title:Communications biology, 2021-05, Vol.4 (1), p.528-528, Article 528
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Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace
Author / Creator:Heimhalt, Maren ; Berndt, Alex ; Wagstaff, Jane ; Anandapadamanaban, Madhanagopal ; Perisic, Olga ; Maslen, Sarah ; McLaughlin, Stephen ; Yu, Conny Wing-Heng ; Masson, Glenn R ; Boland, Andreas ; Ni, Xiaodan ; Yamashita, Keitaro ; Murshudov, Garib N ; Skehel, Mark ; Freund, Stefan M ; Williams, Roger L
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2021-09, Vol.10
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ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes
Author / Creator:Nixon-Abell, Jonathon ; Ruggeri, Francesco S. ; Qamar, Seema ; Herling, Therese W. ; Czekalska, Magdalena A. ; Shen, Yi ; Wang, Guozhen ; King, Christopher ; Fernandopulle, Michael S. ; Sneideris, Tomas ; Watson, Joseph L. ; Pillai, Visakh V. S. ; Meadows, William ; Henderson, James W. ; Chambers, Joseph E. ; Wagstaff, Jane L. ; Williams, Sioned H. ; Coyle, Helena ; Šneiderienė, Greta ; Lu, Yuqian ; Zhang, Shuyuan ; Marciniak, Stefan J. ; Freund, Stefan M. V. ; Derivery, Emmanuel ; Ward, Michael E. ; Vendruscolo, Michele ; Knowles, Tuomas P. J. ; St George-Hyslop, Peter
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-03, Vol.16 (1), p.2814-19, Article 2814
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The complete folding pathway of a protein from nanoseconds to microseconds
Author / Creator:Mayor, Ugo ; Guydosh, Nicholas R. ; Johnson, Christopher M. ; Grossmann, J. Günter ; Sato, Satoshi ; Jas, Gouri S. ; Freund, Stefan M. V. ; Alonso, Darwin O. V. ; Daggett, Valerie ; Fersht, Alan R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2003-02, Vol.421 (6925), p.863-867
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Molecular basis of histone H3K36me3 recognition by the PWWP domain of Brpf1
Author / Creator:Vezzoli, Alessandro ; Bonadies, Nicolas ; Allen, Mark D ; Freund, Stefan M V ; Santiveri, Clara M ; Kvinlaug, Brynn T ; Huntly, Brian J P ; Göttgens, Berthold ; Bycroft, Mark
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2010-05, Vol.17 (5), p.617-619
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Showing 1 to 20 of 60 results

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Structure of PINK1 in complex with its substrate ubiquitin

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Juxtaposition of Bub1 and Cdc20 on phosphorylated Mad1 during catalytic mitotic checkpoint complex assembly

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TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control

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The native structure of the assembled matrix protein 1 of influenza A virus

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A Role for the ESCRT System in Cell Division in Archaea

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FtsA forms actin-like protofilaments

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Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne

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Regulation of Dishevelled DEP domain swapping by conserved phosphorylation sites

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Assembly, analysis and architecture of atypical ubiquitin chains

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HIV-1 capsid undergoes coupled binding and isomerization by the nuclear pore protein NUP358

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Bacterial divisome protein FtsA forms curved antiparallel double filaments when binding to FtsN

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Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53

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Quaternary structures of tumor suppressor p53 and a specific p53-DNA complex

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Domain–domain interactions in full-length p53 and a specific DNA complex probed by methyl NMR spectroscopy

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Self-correcting mismatches during high-fidelity DNA replication

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SWI/SNF subunit BAF155 N-terminus structure informs the impact of cancer-associated mutations and reveals a potential drug binding site

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Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace

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ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes

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The complete folding pathway of a protein from nanoseconds to microseconds

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Molecular basis of histone H3K36me3 recognition by the PWWP domain of Brpf1

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