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ArticlesPeer ReviewedFull Text
P2X7 receptor regulates osteoclast function and bone loss in a mouse model of osteoporosis
Author / Creator:Wang, Ning ; Agrawal, Ankita ; Jørgensen, Niklas Rye ; Gartland, Alison
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-02, Vol.8 (1), p.3507-10, Article 3507
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Targeting metastasis in paediatric bone sarcomas
Author / Creator:Bull, Emma C ; Singh, Archana ; Harden, Amy M ; Soanes, Kirsty ; Habash, Hala ; Toracchio, Lisa ; Carrabotta, Marianna ; Schreck, Christina ; Shah, Karan M ; Riestra, Paulina Velasco ; Chantoiseau, Margaux ; Da Costa, Maria Eugénia Marques ; Moquin-Beaudry, Gaël ; Pantziarka, Pan ; Essiet, Edidiong Akanimo ; Gerrand, Craig ; Gartland, Alison ; Bojmar, Linda ; Fahlgren, Anna ; Marchais, Antonin ; Papakonstantinou, Evgenia ; Tomazou, Eleni M ; Surdez, Didier ; Heymann, Dominique ; Cidre-Aranaz, Florencia ; Fromigue, Olivia ; Sexton, Darren W ; Herold, Nikolas ; Grünewald, Thomas G P ; Scotlandi, Katia ; Nathrath, Michaela ; Green, Darrell
Publisher:England: BioMed Central Ltd
Journal title:Molecular cancer, 2025-05, Vol.24 (1), p.153-29
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Inhibiting the P2X4 Receptor Suppresses Prostate Cancer Growth In Vitro and In Vivo, Suggesting a Potential Clinical Target
Author / Creator:He, Jiepei ; Zhou, Yuhan ; Arredondo Carrera, Hector M. ; Sprules, Alexandria ; Neagu, Ramona ; Zarkesh, Sayyed Amin ; Eaton, Colby ; Luo, Jian ; Gartland, Alison ; Wang, Ning
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2020-11, Vol.9 (11), p.2511
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A novel prostaglandin E receptor 4 (EP4) small molecule antagonist induces articular cartilage regeneration
Author / Creator:Jin, Yunyun ; Liu, Qianqian ; Chen, Peng ; Zhao, Siyuan ; Jiang, Wenhao ; Wang, Fanhua ; Li, Peng ; Zhang, Yuanjin ; Lu, Weiqiang ; Zhong, Tao P. ; Ma, Xinran ; Wang, Xin ; Gartland, Alison ; Wang, Ning ; Shah, Karan Mehul ; Zhang, Hankun ; Cao, Xu ; Yang, Lei ; Liu, Mingyao ; Luo, Jian
Publisher:Singapore: Springer Singapore
Journal title:Cell discovery, 2022-03, Vol.8 (1), p.24-24, Article 24
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C‐terminal variants of the P2X7 receptor are associated with prostate cancer progression and bone metastasis – evidence from clinical and pre‐clinical data
Author / Creator:Song, Haiping ; Arredondo Carrera, Hector Manuel ; Sprules, Alexandria ; Ji, Ying ; Zhang, Tongsong ; He, Jiepei ; Lawrence, Eleanor ; Gartland, Alison ; Luo, Jian ; Wang, Ning
Publisher:United States: John Wiley & Sons, Inc
Journal title:Cancer communications (London, England), 2023-03, Vol.43 (3), p.400-404
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Human P2X7 Receptor Causes Cycle Arrest in RPMI-8226 Myeloma Cells to Alter the Interaction with Osteoblasts and Osteoclasts
Author / Creator:Agrawal, Ankita ; S. Kruse, Lars ; J. Vangsted, Annette ; Gartland, Alison ; R. Jørgensen, Niklas
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2020-10, Vol.9 (11), p.2341
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RETRACTED ARTICLE: The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase
Author / Creator:Cox, Thomas R. ; Rumney, Robin M. H. ; Schoof, Erwin M. ; Perryman, Lara ; Høye, Anette M. ; Agrawal, Ankita ; Bird, Demelza ; Latif, Norain Ab ; Forrest, Hamish ; Evans, Holly R. ; Huggins, Iain D. ; Lang, Georgina ; Linding, Rune ; Gartland, Alison ; Erler, Janine T.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-06, Vol.522 (7554), p.106-110
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Genetic Background Strongly Influences the Bone Phenotype of P2X7 Receptor Knockout Mice
Author / Creator:Schwarz, Peter ; Jorgensen, Niklas Rye ; Syberg, Susanne ; Steinberg, Thomas H. ; Chessell, Iain ; Teilmann, Jenni ; Petersen, Solveig ; Jensen, Jens-Erik Beck ; Gartland, Alison
Publisher:Cairo, Egypt: Hindawi Limiteds
Journal title:Journal of Osteoporosis, 2012-01, Vol.2012 (2012), p.63-71
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The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase
Author / Creator:Cox, Thomas R ; Rumney, Robin M H ; Schoof, Erwin M ; Perryman, Lara ; Høye, Anette M ; Agrawal, Ankita ; Bird, Demelza ; Latif, Norain Ab ; Forrest, Hamish ; Evans, Holly R ; Huggins, Iain D ; Lang, Georgina ; Linding, Rune ; Gartland, Alison ; Erler, Janine T
Publisher:England: Nature Publishing Group
Journal title:Nature (London), 2015-06, Vol.522 (7554), p.106-110
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RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formation and bone metastasis
Author / Creator:Yue, Zhiying ; Niu, Xin ; Yuan, Zengjin ; Qin, Qin ; Jiang, Wenhao ; He, Liang ; Gao, Jingduo ; Ding, Yi ; Liu, Yanxi ; Xu, Ziwei ; Li, Zhenxi ; Yang, Zhengfeng ; Li, Rong ; Xue, Xiwen ; Gao, Yankun ; Yue, Fei ; Zhang, Xiang H.-F. ; Hu, Guohong ; Wang, Yi ; Li, Yi ; Chen, Geng ; Siwko, Stefan ; Gartland, Alison ; Wang, Ning ; Xiao, Jianru ; Liu, Mingyao ; Luo, Jian
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2022-01, Vol.132 (2)
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The strategy and clinical relevance of in vitro models of MAP resistance in osteosarcoma: a systematic review
Author / Creator:Tippett, Victoria L. ; Tattersall, Luke ; Ab Latif, Norain B. ; Shah, Karan M. ; Lawson, Michelle A. ; Gartland, Alison
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2023-01, Vol.42 (4), p.259-277
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Distinct Concentration-Dependent Molecular Pathways Regulate Bone Cell Responses to Cobalt and Chromium Exposure from Joint Replacement Prostheses
Author / Creator:Shah, Karan M. ; Dunning, Mark J. ; Gartland, Alison ; Wilkinson, J. Mark
Publisher:Basel: MDPI AG
Journal title:International journal of molecular sciences, 2021-05, Vol.22 (10), p.5225
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Retraction Note: The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase
Author / Creator:Cox, Thomas R. ; Rumney, Robin M. H. ; Schoof, Erwin M. ; Perryman, Lara ; Høye, Anette M. ; Agrawal, Ankita ; Bird, Demelza ; Latif, Norain Ab ; Forrest, Hamish ; Evans, Holly R. ; Huggins, Iain D. ; Lang, Georgina ; Linding, Rune ; Gartland, Alison ; Erler, Janine T.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2023-05, Vol.617 (7959), p.208-208
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PTH(1–34) treatment and/or mechanical loading have different osteogenic effects on the trabecular and cortical bone in the ovariectomized C57BL/6 mouse
Author / Creator:Roberts, Bryant C. ; Arredondo Carrera, Hector M. ; Zanjani-pour, Sahand ; Boudiffa, Maya ; Wang, Ning ; Gartland, Alison ; Dall’Ara, Enrico
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-06, Vol.10 (1), p.8889-8889, Article 8889
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The Kinesin Gene KIF26B Modulates the Severity of Post-Traumatic Heterotopic Ossification
Author / Creator:Pickering, George A. E. ; Felix-Ilemhenbhio, Favour ; Clark, Matthew J. ; Kocsy, Klaudia ; Simpson, Jonathan ; Bellantuono, Ilaria ; Gartland, Alison ; Wilkinson, Jeremy Mark ; Hatzikotoulas, Konstantinos ; Kiss-Toth, Endre
Publisher:Basel: MDPI AG
Journal title:International journal of molecular sciences, 2022-08, Vol.23 (16), p.9203
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RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formation and bone metastasis
Author / Creator:Yue, Zhiying ; Niu, Xin ; Yuan, Zengjin ; Qin, Qin ; Jiang, Wenhao ; He, Liang ; Gao, Jingduo ; Ding, Yi ; Liu, Yanxi ; Xu, Ziwei ; Li, Zhenxi ; Yang, Zhengfeng ; Li, Rong ; Xue, Xiwen ; Gao, Yankun ; Yue, Fei ; Zhang, Xiang H.-F ; Hu, Guohong ; Wang, Yi ; Li, Yi ; Chen, Geng ; Siwko, Stefan ; Gartland, Alison ; Wang, Ning ; Xiao, Jianru ; Liu, Mingyao ; Luo, Jian
Publisher:American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2022-01, Vol.132 (2)
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RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formation and bone metastasis
Author / Creator:Yue, Zhiying ; Niu, Xin ; Yuan, Zengjin ; Qin, Qin ; Jiang, Wenhao ; He, Liang ; Gao, Jingduo ; Ding, Yi ; Liu, Yanxi ; Xu, Ziwei ; Li, Zhenxi ; Yang, Zhengfeng ; Li, Rong ; Xue, Xiwen ; Gao, Yankun ; Yue, Fei ; Zhang, Xiang H-F ; Hu, Guohong ; Wang, Yi ; Li, Yi ; Chen, Geng ; Siwko, Stefan ; Gartland, Alison ; Wang, Ning ; Xiao, Jianru ; Liu, Mingyao ; Luo, Jian
Publisher:Ann Arbor: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2022-01, Vol.132 (2), p.0_1-19
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Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal women
Author / Creator:Gartland, Alison ; Skarratt, Kristen K ; Hocking, Lynne J ; Parsons, Claire ; Stokes, Leanne ; Jørgensen, Niklas Rye ; Fraser, William D ; Reid, David M ; Gallagher, James A ; Wiley, James S
Publisher:Basingstoke: Nature Publishing Group
Journal title:European journal of human genetics : EJHG, 2012-05, Vol.20 (5), p.559-564
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Single-nucleotide polymorphisms in the P2X7 receptor gene are associated with post-menopausal bone loss and vertebral fractures
Author / Creator:Jørgensen, Niklas R ; Husted, Lise B ; Skarratt, Kristen K ; Stokes, Leanne ; Tofteng, Charlotte L ; Kvist, Torben ; Jensen, Jens-Erik B ; Eiken, Pia ; Brixen, Kim ; Fuller, Stephen ; Clifton-Bligh, Rory ; Gartland, Alison ; Schwarz, Peter ; Langdahl, Bente L ; Wiley, James S
Publisher:Basingstoke: Nature Publishing Group
Journal title:European journal of human genetics : EJHG, 2012-06, Vol.20 (6), p.675-681
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RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formation and bone metastasis RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formatio...
Author / Creator:Zhiying Yue ; Xin Niu ; Zengjin Yuan ; Qin Qin ; Wenhao Jiang ; Liang He ; Jingduo Gao ; Yi Ding ; Yanxi Liu ; Ziwei Xu ; Zhenxi Li ; Zhengfeng Yang ; Rong Li ; Xiwen Xue ; Yankun Gao ; Fei Yue ; Xiang H.-F. Zhang ; Guohong Hu ; Yi Wang ; Yi Li ; Geng Chen ; Stefan Siwko ; Alison Gartland ; Ning Wang ; Jianru Xiao ; Mingyao Liu ; Jian Luo
Publisher:American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2022-01, Vol.132 (2)
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P2X7 receptor regulates osteoclast function and bone loss in a mouse model of osteoporosis

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Targeting metastasis in paediatric bone sarcomas

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Inhibiting the P2X4 Receptor Suppresses Prostate Cancer Growth In Vitro and In Vivo, Suggesting a Potential Clinical Target

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A novel prostaglandin E receptor 4 (EP4) small molecule antagonist induces articular cartilage regeneration

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C‐terminal variants of the P2X7 receptor are associated with prostate cancer progression and bone metastasis – evidence from clinical and pre‐clinical data

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Human P2X7 Receptor Causes Cycle Arrest in RPMI-8226 Myeloma Cells to Alter the Interaction with Osteoblasts and Osteoclasts

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RETRACTED ARTICLE: The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase

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Genetic Background Strongly Influences the Bone Phenotype of P2X7 Receptor Knockout Mice

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The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase

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RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formation and bone metastasis

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The strategy and clinical relevance of in vitro models of MAP resistance in osteosarcoma: a systematic review

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Distinct Concentration-Dependent Molecular Pathways Regulate Bone Cell Responses to Cobalt and Chromium Exposure from Joint Replacement Prostheses

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Retraction Note: The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase

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PTH(1–34) treatment and/or mechanical loading have different osteogenic effects on the trabecular and cortical bone in the ovariectomized C57BL/6 mouse

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The Kinesin Gene KIF26B Modulates the Severity of Post-Traumatic Heterotopic Ossification

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RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formation and bone metastasis

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RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formation and bone metastasis

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Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal women

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Single-nucleotide polymorphisms in the P2X7 receptor gene are associated with post-menopausal bone loss and vertebral fractures

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RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formation and bone metastasis RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formatio...

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