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ArticlesPeer ReviewedFull Text
Whole-genome sequencing reveals progressive versus stable myeloma precursor conditions as two distinct entities
Author / Creator:Oben, Bénedith ; Froyen, Guy ; Maclachlan, Kylee H. ; Leongamornlert, Daniel ; Abascal, Federico ; Zheng-Lin, Binbin ; Yellapantula, Venkata ; Derkach, Andriy ; Geerdens, Ellen ; Diamond, Benjamin T. ; Arijs, Ingrid ; Maes, Brigitte ; Vanhees, Kimberly ; Hultcrantz, Malin ; Manasanch, Elisabet E. ; Kazandjian, Dickran ; Lesokhin, Alexander ; Dogan, Ahmet ; Zhang, Yanming ; Mikulasova, Aneta ; Walker, Brian ; Morgan, Gareth ; Campbell, Peter J. ; Landgren, Ola ; Rummens, Jean-Luc ; Bolli, Niccolò ; Maura, Francesco
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-03, Vol.12 (1), p.1861-11, Article 1861
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Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires β-catenin activity to drive T-cell acute lymphoblastic leukemia
Author / Creator:Van Thillo, Quentin ; De Bie, Jolien ; Seneviratne, Janith A. ; Demeyer, Sofie ; Omari, Sofia ; Balachandran, Anushree ; Zhai, Vicki ; Tam, Wai L. ; Sweron, Bram ; Geerdens, Ellen ; Gielen, Olga ; Provost, Sarah ; Segers, Heidi ; Boeckx, Nancy ; Marshall, Glenn M. ; Cheung, Belamy B. ; Isobe, Kiyotaka ; Kato, Itaru ; Takita, Junko ; Amos, Timothy G. ; Deveson, Ira W. ; McCalmont, Hannah ; Lock, Richard B. ; Oxley, Ethan P. ; Garwood, Maximilian M. ; Dickins, Ross A. ; Uyttebroeck, Anne ; Carter, Daniel R. ; Cools, Jan ; de Bock, Charles E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-07, Vol.12 (1), p.4164-15, Article 4164
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Comprehensive Analysis of Transcriptome Variation Uncovers Known and Novel Driver Events in T-Cell Acute Lymphoblastic Leukemia
Author / Creator:Kalender Atak, Zeynep ; Gianfelici, Valentina ; Hulselmans, Gert ; De Keersmaecker, Kim ; Devasia, Arun George ; Geerdens, Ellen ; Mentens, Nicole ; Chiaretti, Sabina ; Durinck, Kaat ; Uyttebroeck, Anne ; Vandenberghe, Peter ; Wlodarska, Iwona ; Cloos, Jacqueline ; Foà, Robin ; Speleman, Frank ; Cools, Jan ; Aerts, Stein
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2013-12, Vol.9 (12), p.e1003997
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Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics
Author / Creator:Froyen, Guy ; Volders, Pieter‐Jan ; Geerdens, Ellen ; Berden, Severine ; Van der Meulen, Joni ; De Cock, Aaron ; Vermeire, Stefanie ; Van Huysse, Jacques ; Barsy, Marie ; Beniuga, Gabriela ; Leng, Wendy W. J. ; Jansen, Anne M. L. ; Demers, Imke ; Ozgur, Zeliha ; Dubbink, Hendrikus Jan ; Speel, Ernst‐Jan M. ; IJcken, Wilfred F. J. ; Maes, Brigitte
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2025-06, Vol.19 (6), p.1797-1810
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High Accuracy Mutation Detection in Leukemia on a Selected Panel of Cancer Genes
Author / Creator:Kalender Atak, Zeynep ; De Keersmaecker, Kim ; Gianfelici, Valentina ; Geerdens, Ellen ; Vandepoel, Roel ; Pauwels, Daphnie ; Porcu, Michaël ; Lahortiga, Idoya ; Brys, Vanessa ; Dirks, Willy G. ; Quentmeier, Hilmar ; Cloos, Jacqueline ; Cuppens, Harry ; Uyttebroeck, Anne ; Vandenberghe, Peter ; Cools, Jan ; Aerts, Stein
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-06, Vol.7 (6), p.e38463
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Diagnostic Validation of a Comprehensive Targeted Panel for Broad Mutational and Biomarker Analysis in Solid Tumors
Author / Creator:Froyen, Guy ; Geerdens, Ellen ; Berden, Severine ; Cruys, Bert ; Maes, Brigitte
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2022-05, Vol.14 (10), p.2457
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Single-cell sequencing reveals the origin and the order of mutation acquisition in T-cell acute lymphoblastic leukemia
Author / Creator:De Bie, Jolien ; Demeyer, Sofie ; Alberti-Servera, Llucia ; Geerdens, Ellen ; Segers, Heidi ; Broux, Michaël ; De Keersmaecker, Kim ; Michaux, Lucienne ; Vandenberghe, Peter ; Voet, Thierry ; Boeckx, Nancy ; Uyttebroeck, Anne ; Cools, Jan
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2018-06, Vol.32 (6), p.1358-1369
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Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia
Author / Creator:De Keersmaecker, Kim ; Atak, Zeynep Kalender ; Li, Ning ; Vicente, Carmen ; Patchett, Stephanie ; Girardi, Tiziana ; Gianfelici, Valentina ; Geerdens, Ellen ; Clappier, Emmanuelle ; Porcu, Michaël ; Lahortiga, Idoya ; Lucà, Rossella ; Yan, Jiekun ; Hulselmans, Gert ; Vranckx, Hilde ; Vandepoel, Roel ; Sweron, Bram ; Jacobs, Kris ; Mentens, Nicole ; Wlodarska, Iwona ; Cauwelier, Barbara ; Cloos, Jacqueline ; Soulier, Jean ; Uyttebroeck, Anne ; Bagni, Claudia ; Hassan, Bassem A ; Vandenberghe, Peter ; Johnson, Arlen W ; Aerts, Stein ; Cools, Jan
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2013-02, Vol.45 (2), p.186-190
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ArticlesPeer ReviewedFull Text
Novel gene fusion discovery in Spitz tumours and its relevance in diagnostics
Author / Creator:Delsupehe, Louis ; Steelandt, Thomas ; Lemahieu, Julie ; Volders, Pieter-Jan ; Geerdens, Ellen ; Berden, Severine ; Daniels, Annick ; Froyen, Guy ; Maes, Brigitte
Publisher:Heidelberg: Springer Nature B.V
Journal title:Virchows Archiv : an international journal of pathology, 2024-08, Vol.485 (2), p.269-279
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The T-cell leukemia-associated ribosomal RPL10 R98S mutation enhances JAK-STAT signaling
Author / Creator:Girardi, T ; Vereecke, S ; Sulima, S O ; Khan, Y ; Fancello, L ; Briggs, J W ; Schwab, C ; de Beeck, J Op ; Verbeeck, J ; Royaert, J ; Geerdens, E ; Vicente, C ; Bornschein, S ; Harrison, C J ; Meijerink, J P ; Cools, J ; Dinman, J D ; Kampen, K R ; De Keersmaecker, K
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2018-03, Vol.32 (3), p.809-819
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ArticlesPeer ReviewedFull Text
RPL5 on 1p22.1 is recurrently deleted in multiple myeloma and its expression is linked to bortezomib response
Author / Creator:Hofman, I J F ; van Duin, M ; De Bruyne, E ; Fancello, L ; Mulligan, G ; Geerdens, E ; Garelli, E ; Mancini, C ; Lemmens, H ; Delforge, M ; Vandenberghe, P ; Wlodarska, I ; Aspesi, A ; Michaux, L ; Vanderkerken, K ; Sonneveld, P ; De Keersmaecker, K
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2017-08, Vol.31 (8), p.1706-1714
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The Dynamics of Nucleotide Variants in the Progression from Low–Intermediate Myeloma Precursor Conditions to Multiple Myeloma: Studying Serial Samples with a Targeted Sequencing Approach
Author / Creator:Oben, Bénedith ; Cosemans, Charlotte ; Geerdens, Ellen ; Linsen, Loes ; Vanhees, Kimberly ; Maes, Brigitte ; Theunissen, Koen ; Cruys, Bert ; Lionetti, Marta ; Arijs, Ingrid ; Bolli, Niccolò ; Froyen, Guy ; Rummens, Jean-Luc
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2022-02, Vol.14 (4), p.1035
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Two Separate Clusters of SARS-CoV-2 Delta Variant Infections in a Group of 41 Students Travelling from India: An Illustration of the Need for Rigorous Testing and Quarantine
Author / Creator:Van Elslande, Jan ; Kerckhofs, Femke ; Cuypers, Lize ; Wollants, Elke ; Potter, Barney ; Vankeerberghen, Anne ; Cattoir, Lien ; Holderbeke, Astrid ; Behillil, Sylvie ; Gorissen, Sarah ; Bloemen, Mandy ; Arnout, Jef ; Van Ranst, Marc ; Van Weyenbergh, Johan ; Maes, Piet ; Baele, Guy ; Vermeersch, Pieter ; André, Emmanuel
Publisher:Basel: MDPI AG
Journal title:Viruses, 2022-05, Vol.14 (6), p.1198
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ArticlesPeer ReviewedFull Text
Reference genes for qPCR assays in toxic metal and salinity stress in two flatworm model organisms
Author / Creator:Plusquin, Michelle ; DeGheselle, Olivier ; Cuypers, Ann ; Geerdens, Ellen ; Van Roten, Andromeda ; Artois, Tom ; Smeets, Karen
Publisher:Boston: Springer US
Journal title:Ecotoxicology (London), 2012-03, Vol.21 (2), p.475-484
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Comprehensive Analysis of Transcriptome Variation Uncovers Known and Novel Driver Events in T-Cell Acute Lymphoblastic Leukemia: e1003997
Author / Creator:Atak, Zeynep Kalender ; Gianfelici, Valentina ; Hulselmans, Gert ; Keersmaecker, Kim De ; Devasia, Arun George ; Geerdens, Ellen ; Mentens, Nicole ; Chiaretti, Sabina ; Durinck, Kaat ; Uyttebroeck, Anne ; Vandenberghe, Peter ; Wlodarska, Iwona ; Cloos, Jacqueline ; Foà, Robin ; Speleman, Frank ; Cools, Jan ; Aerts, Stein
Publisher:San Francisco: Public Library of Science
Journal title:PLoS genetics, 2013-12, Vol.9 (12)
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ArticlesFull Text
Whole genome sequencing provides evidence of two biologically and clinically distinct entities of asymptomatic monoclonal gammopathies: progressive versus stable myeloma precursor condition
Author / Creator:Oben, Bénedith ; Froyen, Guy ; Maclachlan, Kylee H ; Leongamornlert, Daniel ; Abascal, Federico ; Zheng-Lin, Binbin ; Yellapantula, Venkata ; Derkach, Andriy ; Geerdens, Ellen ; Diamond, Benjamin T ; Arijs, Ingrid ; Maes, Brigitte ; Vanhees, Kimberly ; Hultcrantz, Malin ; Manasanch, Elisabet E ; Kazandjian, Dickran ; Dogan, Ahmet ; Zhang, Yanming ; Mikulasova, Aneta ; Walker, Brian ; Morgan, Gareth ; Campbell, Peter J ; Landgren, Ola ; Rummens, Jean-Luc ; Bolli, Niccolò ; Francesco, Maura
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-11
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Nationwide quality assurance of high-throughput diagnostic molecular testing during the SARS-CoV-2 pandemic: role of the Belgian National Reference Centre
Author / Creator:Janssen, Reile ; Cuypers, Lize ; Laenen, Lies ; Keyaerts, Els ; Beuselinck, Kurt ; Janssenswillen, Sunita ; Slechten, Bram ; Bode, Jannes ; Wollants, Elke ; Van Laethem, Kristel ; Rector, Annabel ; Bloemen, Mandy ; Sijmons, Anke ; de Schaetzen, Nathalie ; Capron, Arnaud ; Van Baelen, Kurt ; Pascal, Thierry ; Vermeiren, Céline ; Bureau, Fabrice ; Vandesompele, Jo ; De Smet, Pieter ; Uten, Wouter ; Malonne, Hugues ; Kerkhofs, Pierre ; De Cock, Jo ; Matheeussen, Veerle ; Verhasselt, Bruno ; Gillet, Laurent ; Detry, Gautier ; Bearzatto, Bertrand ; Degosserie, Jonathan ; Henin, Coralie ; Pairoux, Gregor ; Maes, Piet ; Van Ranst, Marc ; Lagrou, Katrien ; Dequeker, Elisabeth ; André, Emmanuel
Publisher:London: BioMed Central
Journal title:Virology journal, 2024-02, Vol.21 (1), p.40-40, Article 40
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Whole-genome sequencing reveals progressive versus stable myeloma precursor conditions as two distinct entities

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Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires β-catenin activity to drive T-cell acute lymphoblastic leukemia

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Comprehensive Analysis of Transcriptome Variation Uncovers Known and Novel Driver Events in T-Cell Acute Lymphoblastic Leukemia

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Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

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High Accuracy Mutation Detection in Leukemia on a Selected Panel of Cancer Genes

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Diagnostic Validation of a Comprehensive Targeted Panel for Broad Mutational and Biomarker Analysis in Solid Tumors

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Single-cell sequencing reveals the origin and the order of mutation acquisition in T-cell acute lymphoblastic leukemia

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Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia

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Novel gene fusion discovery in Spitz tumours and its relevance in diagnostics

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The T-cell leukemia-associated ribosomal RPL10 R98S mutation enhances JAK-STAT signaling

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RPL5 on 1p22.1 is recurrently deleted in multiple myeloma and its expression is linked to bortezomib response

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The Dynamics of Nucleotide Variants in the Progression from Low–Intermediate Myeloma Precursor Conditions to Multiple Myeloma: Studying Serial Samples with a Targeted Sequencing Approach

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Two Separate Clusters of SARS-CoV-2 Delta Variant Infections in a Group of 41 Students Travelling from India: An Illustration of the Need for Rigorous Testing and Quarantine

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Reference genes for qPCR assays in toxic metal and salinity stress in two flatworm model organisms

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Comprehensive Analysis of Transcriptome Variation Uncovers Known and Novel Driver Events in T-Cell Acute Lymphoblastic Leukemia: e1003997

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Whole genome sequencing provides evidence of two biologically and clinically distinct entities of asymptomatic monoclonal gammopathies: progressive versus stable myeloma precursor condition

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Nationwide quality assurance of high-throughput diagnostic molecular testing during the SARS-CoV-2 pandemic: role of the Belgian National Reference Centre

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