Restricting extracellular Ca2+ on gefitinib-resistant non-small cell lung cancer cells reverses alte...
Restricting extracellular Ca2+ on gefitinib-resistant non-small cell lung cancer cells reverses altered epidermal growth factor-mediated Ca2+ response, which consequently enhances gefitinib sensitivity
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San Francisco: Public Library of Science
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Language
English
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San Francisco: Public Library of Science
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Contents
Non-small cell lung cancer (NSCLC), one of the leading causes of cancer-related death, has a low 5-year survival rate owing to the inevitable acquired resistance toward antitumor drugs, platinum-based chemotherapy, and targeted therapy. Epidermal growth factor (EGF)-EGF receptor (EGFR) signaling activates downstream events leading to phospholipase...
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Full title
Restricting extracellular Ca2+ on gefitinib-resistant non-small cell lung cancer cells reverses altered epidermal growth factor-mediated Ca2+ response, which consequently enhances gefitinib sensitivity
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TN_cdi_plos_journals_2437106640
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2437106640
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0238155
