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171 results for Genetic+Vectors+-+pharmacology

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ArticlesPeer ReviewedFull Text
The current landscape of nucleic acid therapeutics
Author / Creator:Kulkarni, Jayesh A. ; Witzigmann, Dominik ; Thomson, Sarah B. ; Chen, Sam ; Leavitt, Blair R. ; Cullis, Pieter R. ; van der Meel, Roy
Publisher:London: Nature Publishing Group UK
Journal title:Nature nanotechnology, 2021-06, Vol.16 (6), p.630-643
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ArticlesPeer ReviewedFull Text
Tumour-targeting bacteria engineered to fight cancer
Author / Creator:Zhou, Shibin ; Gravekamp, Claudia ; Bermudes, David ; Liu, Ke
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2018-12, Vol.18 (12), p.727-743
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Intracerebral gene therapy in children with mucopolysaccharidosis type IIIB syndrome: an uncontrolled phase 1/2 clinical trial
Author / Creator:Tardieu, Marc ; Zérah, Michel ; Gougeon, Marie-Lise ; Ausseil, Jérome ; de Bournonville, Stéphanie ; Husson, Béatrice ; Zafeiriou, Dimitrios ; Parenti, Giancarlo ; Bourget, Philippe ; Poirier, Béatrice ; Furlan, Valérie ; Artaud, Cécile ; Baugnon, Thomas ; Roujeau, Thomas ; Crystal, Ronald G ; Meyer, Christian ; Deiva, Kumaran ; Heard, Jean-Michel
Publisher:England: Elsevier Ltd
Journal title:Lancet neurology, 2017-09, Vol.16 (9), p.712-720
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Targeted inhibition of SIRT6 via engineered exosomes impairs tumorigenesis and metastasis in prostate cancer
Author / Creator:Han, Qing ; Xie, Qian Rueben ; Li, Fan ; Cheng, Yirui ; Wu, Tingyu ; Zhang, Yanshuang ; Lu, Xin ; Wong, Alice S.T. ; Sha, Jianjun ; Xia, Weiliang
Publisher:Australia: Ivyspring International Publisher Pty Ltd
Journal title:Theranostics, 2021-01, Vol.11 (13), p.6526-6541
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ArticlesPeer ReviewedFull Text
Applications of Ultrasound-Mediated Drug Delivery and Gene Therapy
Author / Creator:Sitta, Juliana ; Howard, Candace M.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2021-10, Vol.22 (21), p.11491
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ArticlesPeer ReviewedFull Text
Protein-based human iPS cells efficiently generate functional dopamine neurons and can treat a rat model of Parkinson disease
Author / Creator:Rhee, Yong-Hee ; Ko, Ji-Yun ; Chang, Mi-Yoon ; Yi, Sang-Hoon ; Kim, Dohoon ; Kim, Chun-Hyung ; Shim, Jae-Won ; Jo, A-Young ; Kim, Byung-Woo ; Lee, Hyunsu ; Lee, Suk-Ho ; Suh, Wonhee ; Park, Chang-Hwan ; Koh, Hyun-Chul ; Lee, Yong-Sung ; Lanza, Robert ; Kim, Kwang-Soo ; Lee, Sang-Hun
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2011-06, Vol.121 (6), p.2326-2335
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ArticlesPeer ReviewedFull Text
GDF11 Protects against Endothelial Injury and Reduces Atherosclerotic Lesion Formation in Apolipoprotein E-Null Mice
Author / Creator:Mei, Wen ; Xiang, Guangda ; Li, Yixiang ; Li, Huan ; Xiang, Lingwei ; Lu, Junyan ; Xiang, Lin ; Dong, Jing ; Liu, Min
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2016-11, Vol.24 (11), p.1926-1938
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ArticlesPeer ReviewedFull Text
A novel circular RNA hsa_circRNA_103809/miR-377-3p/GOT1 pathway regulates cisplatin-resistance in non-small cell lung cancer (NSCLC)
Author / Creator:Zhu, Xiang ; Han, Jing ; Lan, Huiyin ; Lin, Qingren ; Wang, Yuezhen ; Sun, Xiaojiang
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2020-12, Vol.20 (1), p.1190-1190, Article 1190
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ssAAVs containing cassettes encoding SaCas9 and guides targeting hepatitis B virus inactivate replication of the virus in cultured cells
Author / Creator:Scott, Tristan ; Moyo, Buhle ; Nicholson, Samantha ; Maepa, Mohube Betty ; Watashi, Koichi ; Ely, Abdullah ; Weinberg, Marc S. ; Arbuthnot, Patrick
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-08, Vol.7 (1), p.7401-11, Article 7401
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ArticlesPeer ReviewedFull Text
CEP290 gene transfer rescues Leber congenital amaurosis cellular phenotype
Author / Creator:Burnight, E R ; Wiley, L A ; Drack, A V ; Braun, T A ; Anfinson, K R ; Kaalberg, E E ; Halder, J A ; Affatigato, L M ; Mullins, R F ; Stone, E M ; Tucker, B A
Publisher:London: Nature Publishing Group UK
Journal title:Gene therapy, 2014-07, Vol.21 (7), p.662-672
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ArticlesPeer ReviewedFull Text
Doxorubicin Improves Cancer Cell Targeting by Filamentous Phage Gene Delivery Vectors
Author / Creator:Tsafa, Effrosyni ; Bentayebi, Kaoutar ; Topanurak, Supachai ; Yata, Teerapong ; Przystal, Justyna ; Fongmoon, Duriya ; Hajji, Nabil ; Waramit, Sajee ; Suwan, Keittisak ; Hajitou, Amin
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-10, Vol.21 (21), p.7867
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ArticlesPeer ReviewedFull Text
The Pharmacology of Gene Therapy
Author / Creator:Ylä-Herttuala, Seppo
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2017-08, Vol.25 (8), p.1731-1732
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ArticlesPeer ReviewedFull Text
Prolonged inhibition of hepatocellular carcinoma cell proliferation by combinatorial expression of defined transcription factors
Author / Creator:Takashima, Yasuo ; Horisawa, Kenichi ; Udono, Miyako ; Ohkawa, Yasuyuki ; Suzuki, Atsushi
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2018-11, Vol.109 (11), p.3543-3553
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ArticlesPeer ReviewedFull Text
Side-by-side comparison of the effects of Gq- and Gi-DREADD-mediated astrocyte modulation on intracellular calcium dynamics and synaptic plasticity in the hippocampal CA1
Author / Creator:Van Den Herrewegen, Yana ; Sanderson, Thomas M. ; Sahu, Surajit ; De Bundel, Dimitri ; Bortolotto, Zuner A. ; Smolders, Ilse
Publisher:England: BioMed Central Ltd
Journal title:Molecular brain, 2021-09, Vol.14 (1), p.144-144, Article 144
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ArticlesPeer ReviewedFull Text
Engineered DNA plasmid reduces immunity to dystrophin while improving muscle force in a model of gene therapy of Duchenne dystrophy
Author / Creator:Ho, Peggy P. ; Lahey, Lauren J. ; Mourkioti, Foteini ; Kraft, Peggy E. ; Filareto, Antonio ; Brandt, Moritz ; Magnusson, Klas E. G. ; Finn, Eric E. ; Chamberlain, Jeffrey S. ; Robinson, William H. ; Blau, Helen M. ; Steinman, Lawrence
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-09, Vol.115 (39), p.E9182-E9191
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ArticlesPeer ReviewedFull Text
Intratumoral expression of IL-12 from lentiviral or RNA vectors acts synergistically with TLR4 agonist (GLA) to generate anti-tumor immunological memory
Author / Creator:Leleux, Jardin A. ; Albershardt, Tina C. ; Reeves, Rebecca ; James, Reice ; Krull, Jordan ; Parsons, Andrea J. ; ter Meulen, Jan ; Berglund, Peter
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-12, Vol.16 (12), p.e0259301
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ArticlesPeer ReviewedFull Text
Defining Phenotype, Tropism, and Retinal Gene Therapy Using Adeno-Associated Viral Vectors (AAVs) in New-Born Brown Norway Rats with a Spontaneous Mutation in Crb1
Author / Creator:Boon, Nanda ; Alves, C. Henrique ; Mulder, Aat A. ; Andriessen, Charlotte A. ; Buck, Thilo M. ; Quinn, Peter M. J. ; Vos, Rogier M. ; Koster, Abraham J. ; Jost, Carolina R. ; Wijnholds, Jan
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2021-03, Vol.22 (7), p.3563
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ArticlesPeer ReviewedFull Text
Anxiolytic effect of GABAergic neurons in the anterior cingulate cortex in a rat model of chronic inflammatory pain
Author / Creator:Shao, Fang-bing ; Fang, Jun-fan ; Wang, Si-si ; Qiu, Meng-ting ; Xi, Dan-ning ; Jin, Xiao-ming ; Liu, Jing-gen ; Shao, Xiao-mei ; Shen, Zui ; Liang, Yi ; Fang, Jian-qiao ; Du, Jun-ying
Publisher:England: BioMed Central Ltd
Journal title:Molecular brain, 2021-09, Vol.14 (1), p.139-139, Article 139
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ArticlesFull Text
Spred2 inhibits epithelial‑mesenchymal transition of colorectal cancer cells by impairing ERK signaling
Author / Creator:Wang, Hao ; Liu, Shuchen ; Kong, Fanxuan ; Xiao, Fengjun ; Li, Yuxiang ; Wang, Hua ; Zhang, Shun ; Huang, Dandan ; Wang, Lisheng ; Yang, Yuefeng
Publisher:Greece: Spandidos Publications
Journal title:Oncology reports, 2020-07, Vol.44 (1), p.174-185
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ArticlesPeer ReviewedFull Text
Single Immunization with Newcastle Disease Virus-Vectored H7N9 Vaccine Confers a Complete Protection Against Challenge with Highly Pathogenic Avian Influenza H7N9 Virus
Author / Creator:Shi, Lei ; Hu, Zenglei ; Hu, Jiao ; Liu, Dong ; He, Lihong ; Liu, Jiao ; Gu, Han ; Gan, Junji ; Wang, Xiaoquan ; Liu, Xiufan
Publisher:United States: American Association of Avian Pathologists Inc
Journal title:Avian diseases, 2019-03, Vol.63 (1), p.61-67
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Showing 1 to 20 of 171 results

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The current landscape of nucleic acid therapeutics

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Tumour-targeting bacteria engineered to fight cancer

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Intracerebral gene therapy in children with mucopolysaccharidosis type IIIB syndrome: an uncontrolled phase 1/2 clinical trial

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Targeted inhibition of SIRT6 via engineered exosomes impairs tumorigenesis and metastasis in prostate cancer

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Applications of Ultrasound-Mediated Drug Delivery and Gene Therapy

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Protein-based human iPS cells efficiently generate functional dopamine neurons and can treat a rat model of Parkinson disease

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GDF11 Protects against Endothelial Injury and Reduces Atherosclerotic Lesion Formation in Apolipoprotein E-Null Mice

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A novel circular RNA hsa_circRNA_103809/miR-377-3p/GOT1 pathway regulates cisplatin-resistance in non-small cell lung cancer (NSCLC)

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ssAAVs containing cassettes encoding SaCas9 and guides targeting hepatitis B virus inactivate replication of the virus in cultured cells

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CEP290 gene transfer rescues Leber congenital amaurosis cellular phenotype

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Doxorubicin Improves Cancer Cell Targeting by Filamentous Phage Gene Delivery Vectors

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The Pharmacology of Gene Therapy

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Prolonged inhibition of hepatocellular carcinoma cell proliferation by combinatorial expression of defined transcription factors

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Side-by-side comparison of the effects of Gq- and Gi-DREADD-mediated astrocyte modulation on intracellular calcium dynamics and synaptic plasticity in the hippocampal CA1

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Engineered DNA plasmid reduces immunity to dystrophin while improving muscle force in a model of gene therapy of Duchenne dystrophy

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Intratumoral expression of IL-12 from lentiviral or RNA vectors acts synergistically with TLR4 agonist (GLA) to generate anti-tumor immunological memory

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Defining Phenotype, Tropism, and Retinal Gene Therapy Using Adeno-Associated Viral Vectors (AAVs) in New-Born Brown Norway Rats with a Spontaneous Mutation in Crb1

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Anxiolytic effect of GABAergic neurons in the anterior cingulate cortex in a rat model of chronic inflammatory pain

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Spred2 inhibits epithelial‑mesenchymal transition of colorectal cancer cells by impairing ERK signaling

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Single Immunization with Newcastle Disease Virus-Vectored H7N9 Vaccine Confers a Complete Protection Against Challenge with Highly Pathogenic Avian Influenza H7N9 Virus

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