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ArticlesPeer ReviewedFull Text
Comparative genomic hybridisation array and DNA sequencing to direct treatment of metastatic breast cancer: a multicentre, prospective trial (SAFIR01/UNICANCER)
Author / Creator:André, Fabrice, Prof ; Bachelot, Thomas, MD ; Commo, Frederic, MSc ; Campone, Mario, Prof ; Arnedos, Monica, MD ; Dieras, Véronique, MD ; Lacroix-Triki, Magali, MD ; Lacroix, Ludovic, PharmPhD ; Cohen, Pascale, PhD ; Gentien, David, MSc ; Adélaide, Jose, PhD ; Dalenc, Florence, MD ; Goncalves, Anthony, MD ; Levy, Christelle, MD ; Ferrero, Jean-Marc, Prof ; Bonneterre, Jacques, Prof ; Lefeuvre, Claudia, MD ; Jimenez, Marta, MSc ; Filleron, Thomas, PhD ; Bonnefoi, Hervé, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2014-03, Vol.15 (3), p.267-274
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The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist
Author / Creator:van Bemmel, Joke G. ; Galupa, Rafael ; Gard, Chris ; Servant, Nicolas ; Picard, Christel ; Davies, James ; Szempruch, Anthony James ; Zhan, Yinxiu ; Żylicz, Jan J. ; Nora, Elphège P. ; Lameiras, Sonia ; de Wit, Elzo ; Gentien, David ; Baulande, Sylvain ; Giorgetti, Luca ; Guttman, Mitchell ; Hughes, Jim R. ; Higgs, Douglas R. ; Gribnau, Joost ; Heard, Edith
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2019-06, Vol.51 (6), p.1024-1034
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Establishment of novel cell lines recapitulating the genetic landscape of uveal melanoma and preclinical validation of mTOR as a therapeutic target
Author / Creator:Amirouchene-Angelozzi, Nabil ; Nemati, Fariba ; Gentien, David ; Nicolas, André ; Dumont, Amaury ; Carita, Guillaume ; Camonis, Jacques ; Desjardins, Laurence ; Cassoux, Nathalie ; Piperno-Neumann, Sophie ; Mariani, Pascale ; Sastre, Xavier ; Decaudin, Didier ; Roman-Roman, Sergio
Publisher:United States: Elsevier B.V
Journal title:Molecular oncology, 2014-12, Vol.8 (8), p.1508-1520
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TTK/hMPS1 Is an Attractive Therapeutic Target for Triple-Negative Breast Cancer
Author / Creator:Maire, Virginie ; Baldeyron, Céline ; Richardson, Marion ; Tesson, Bruno ; Vincent-Salomon, Anne ; Gravier, Eléonore ; Marty-Prouvost, Bérengère ; De Koning, Leanne ; Rigaill, Guillem ; Dumont, Aurélie ; Gentien, David ; Barillot, Emmanuel ; Roman-Roman, Sergio ; Depil, Stéphane ; Cruzalegui, Francisco ; Pierré, Alain ; Tucker, Gordon C. ; Dubois, Thierry
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-05, Vol.8 (5), p.e63712-e63712
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Transcriptome Analysis of Wnt3a-Treated Triple-Negative Breast Cancer Cells
Author / Creator:Maubant, Sylvie ; Tesson, Bruno ; Maire, Virginie ; Ye, Mengliang ; Rigaill, Guillem ; Gentien, David ; Cruzalegui, Francisco ; Tucker, Gordon C. ; Roman-Roman, Sergio ; Dubois, Thierry
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-04, Vol.10 (4), p.e0122333-e0122333
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Molecular profiling of patient-derived breast cancer xenografts
Author / Creator:Reyal, Fabien ; Guyader, Charlotte ; Decraene, Charles ; Lucchesi, Carlo ; Auger, Nathalie ; Assayag, Franck ; De Plater, Ludmilla ; Gentien, David ; Poupon, Marie-France ; Cottu, Paul ; De Cremoux, Patricia ; Gestraud, Pierre ; Vincent-Salomon, Anne ; Fontaine, Jean-Jacques ; Roman-Roman, Sergio ; Delattre, Olivier ; Decaudin, Didier ; Marangoni, Elisabetta
Publisher:England: BioMed Central Ltd
Journal title:Breast cancer research : BCR, 2012-01, Vol.14 (1), p.R11-R11, Article R11
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Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons
Author / Creator:Schaller, Sébastien ; Buttigieg, Dorothée ; Alory, Alysson ; Jacquier, Arnaud ; Barad, Marc ; Merchant, Mark ; Gentien, David ; de la Grange, Pierre ; Haase, Georg
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-03, Vol.114 (12), p.E2486-E2493
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HORMAD1 overexpression predicts response to anthracycline–cyclophosphamide and survival in triple‐negative breast cancers
Author / Creator:El‐Botty, Rania ; Vacher, Sophie ; Mainguené, Juliette ; Briaux, Adrien ; Ibadioune, Sabrina ; Dahmani, Ahmed ; Montaudon, Elodie ; Nemati, Fariba ; Huguet, Léa ; Sourd, Laura ; Morriset, Ludivine ; Château‐Joubert, Sophie ; Dubois, Thierry ; Maire, Virginie ; Lidereau, Rosette ; Rapinat, Audrey ; Gentien, David ; Coussy, Florence ; Bièche, Ivan ; Marangoni, Elisabetta
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2023-10, Vol.17 (10), p.2017-2028
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PARP Inhibition Increases the Response to Chemotherapy in Uveal Melanoma
Author / Creator:de Koning, Leanne ; Decaudin, Didier ; El Botty, Rania ; Nicolas, André ; Carita, Guillaume ; Schuller, Mathieu ; Ouine, Bérengère ; Cartier, Aurélie ; Naguez, Adnan ; Fleury, Justine ; Cooke, Vesselina ; Wylie, Andrew ; Smith, Paul ; Marangoni, Elisabetta ; Gentien, David ; Meseure, Didier ; Mariani, Pascale ; Cassoux, Nathalie ; Piperno-Neumann, Sophie ; Roman-Roman, Sergio ; Némati, Fariba
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2019-05, Vol.11 (6), p.751
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Patient Derived Xenografts (PDX) Models as an Avatar to Assess Personalized Therapy Options in Uveal Melanoma: A Feasibility Study
Author / Creator:Nemati, Fariba ; de Koning, Leanne ; Gentien, David ; Assayag, Franck ; Henry, Emilie ; Ait Rais, Khadija ; Pierron, Gaelle ; Mariani, Odette ; Nijnikoff, Michèle ; Champenois, Gabriel ; Nicolas, André ; Meseure, Didier ; Gardrat, Sophie ; Servant, Nicolas ; Hupé, Philippe ; Kamal, Maud ; Le Tourneau, Christophe ; Piperno-Neumann, Sophie ; Rodrigues, Manuel ; Roman-Roman, Sergio ; Decaudin, Didier ; Mariani, Pascale ; Cassoux, Nathalie
Publisher:MDPI AG
Journal title:Current oncology (Toronto), 2023-10, Vol.30 (10), p.9090-9103
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HRAS is a therapeutic target in malignant chemo-resistant adenomyoepithelioma of the breast
Author / Creator:Bièche, Ivan ; Coussy, Florence ; El-Botty, Rania ; Vacher, Sophie ; Château-Joubert, Sophie ; Dahmani, Ahmed ; Montaudon, Elodie ; Reyes, Cécile ; Gentien, David ; Reyal, Fabien ; Ricci, Francesco ; Nicolas, André ; Marchio, Caterina ; Vincent-Salomon, Anne ; Laé, Marick ; Marangoni, Elisabetta
Publisher:London: BioMed Central Ltd
Journal title:Journal of hematology and oncology, 2021-09, Vol.14 (1), p.1-143, Article 143
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Prospective, multicenter French study evaluating the clinical impact of the Breast Cancer Intrinsic Subtype-Prosigna® Test in the management of early-stage breast cancers
Author / Creator:Hequet, Delphine ; Callens, Céline ; Gentien, David ; Albaud, Benoit ; Mouret-Reynier, Marie-Ange ; Dubot, Coraline ; Cottu, Paul ; Huchon, Cyrille ; Zilberman, Sonia ; Berseneff, Helene ; Foa, Cyril ; Salmon, Rémy ; Roulot, Aurélie ; Lerebours, Florence ; Salomon, Anne ; Ghali, Nadeem ; Morel, Pascale ; Li, Qianyi ; Cayre, Anne ; Guinebretière, Jean-Marc ; Hornberger, John ; Penault-Llorca, Frédérique ; Rouzier, Roman
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-10, Vol.12 (10), p.e0185753-e0185753
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Evaluation of methods for amplification of picogram amounts of total RNA for whole genome expression profiling
Author / Creator:Clément-Ziza, Mathieu ; Gentien, David ; Lyonnet, Stanislas ; Thiery, Jean-Paul ; Besmond, Claude ; Decraene, Charles
Publisher:England: BioMed Central Ltd
Journal title:BMC genomics, 2009-05, Vol.10 (1), p.246-246, Article 246
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A computational method for prioritizing targeted therapies in precision oncology: performance analysis in the SHIVA01 trial
Author / Creator:Petak, Istvan ; Kamal, Maud ; Dirner, Anna ; Bieche, Ivan ; Doczi, Robert ; Mariani, Odette ; Filotas, Peter ; Salomon, Anne ; Vodicska, Barbara ; Servois, Vincent ; Varkondi, Edit ; Gentien, David ; Tihanyi, Dora ; Tresca, Patricia ; Lakatos, Dora ; Servant, Nicolas ; Deri, Julia ; du Rusquec, Pauline ; Hegedus, Csilla ; Bello Roufai, Diana ; Schwab, Richard ; Dupain, Celia ; Valyi-Nagy, Istvan T. ; Le Tourneau, Christophe
Publisher:London: Nature Publishing Group UK
Journal title:NPJ precision oncology, 2021-06, Vol.5 (1), p.59-59, Article 59
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Characterization of Breast Cancer Preclinical Models Reveals a Specific Pattern of Macrophage Polarization
Author / Creator:Vallerand, David ; Massonnet, Gérald ; Kébir, Fatima ; Gentien, David ; Maciorowski, Zofia ; De la Grange, Pierre ; Sigal-Zafrani, Brigitte ; Richardson, Marion ; Humbert, Sandrine ; Thuleau, Aurélie ; Assayag, Franck ; de Plater, Ludmilla ; Nicolas, André ; Scholl, Suzy ; Marangoni, Elisabetta ; Weigand, Stefan ; Roman-Roman, Sergio ; Savina, Ariel ; Decaudin, Didier
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-07, Vol.11 (7), p.e0157670-e0157670
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The Huntington disease protein accelerates breast tumour development and metastasis through ErbB2/HER2 signalling
Author / Creator:Moreira Sousa, Cristovão ; McGuire, John Russel ; Thion, Morgane Sonia ; Gentien, David ; de la Grange, Pierre ; Tezenas du Montcel, Sophie ; Vincent‐Salomon, Anne ; Durr, Alexandra ; Humbert, Sandrine
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2013-02, Vol.5 (2), p.309-325
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Genomic Instability: A Stronger Prognostic Marker Than Proliferation for Early Stage Luminal Breast Carcinomas
Author / Creator:Vincent-Salomon, Anne ; Benhamo, Vanessa ; Gravier, Eléonore ; Rigaill, Guillem ; Gruel, Nadège ; Robin, Stéphane ; de Rycke, Yann ; Mariani, Odette ; Pierron, Gaëlle ; Gentien, David ; Reyal, Fabien ; Cottu, Paul ; Fourquet, Alain ; Rouzier, Roman ; Sastre-Garau, Xavier ; Delattre, Olivier
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-10, Vol.8 (10), p.e76496-e76496
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Respective Prognostic Value of Genomic Grade and Histological Proliferation Markers in Early Stage (pN0) Breast Carcinoma
Author / Creator:Reyal, Fabien ; Bollet, Marc A. ; Caly, Martial ; Gentien, David ; Carpentier, Sabrina ; Peyro-Saint-Paul, Hélène ; Pierga, Jean-Yves ; Cottu, Paul ; Dieras, Véronique ; Sigal-Zafrani, Brigitte ; Vincent-Salomon, Anne ; Sastre-Garau, Xavier
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-04, Vol.7 (4), p.e35184-e35184
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Importance of pre-analytical steps for transcriptome and RT-qPCR analyses in the context of the phase II randomised multicentre trial REMAGUS02 of neoadjuvant chemotherapy in breast cancer patients
Author / Creator:de Cremoux, Patricia ; Valet, Fabien ; Gentien, David ; Lehmann-Che, Jacqueline ; Scott, Véronique ; Tran-Perennou, Carine ; Barbaroux, Catherine ; Servant, Nicolas ; Vacher, Sophie ; Sigal-Zafrani, Brigitte ; Mathieu, Marie-Christine ; Bertheau, Philippe ; Guinebretière, Jean-Marc ; Asselain, Bernard ; Marty, Michel ; Spyratos, Frédérique
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2011-06, Vol.11 (1), p.215-215, Article 215
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A genomic and transcriptomic approach for a differential diagnosis between primary and secondary ovarian carcinomas in patients with a previous history of breast cancer
Author / Creator:Meyniel, Jean-Philippe ; Cottu, Paul H ; Decraene, Charles ; Stern, Marc-Henri ; Couturier, Jérôme ; Lebigot, Ingrid ; Nicolas, André ; Weber, Nina ; Fourchotte, Virginie ; Alran, Séverine ; Rapinat, Audrey ; Gentien, David ; Roman-Roman, Sergio ; Mignot, Laurent ; Sastre-Garau, Xavier
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2010-05, Vol.10 (1), p.222-222, Article 222
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Comparative genomic hybridisation array and DNA sequencing to direct treatment of metastatic breast cancer: a multicentre, prospective trial (SAFIR01/UNICANCER)

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The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist

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Establishment of novel cell lines recapitulating the genetic landscape of uveal melanoma and preclinical validation of mTOR as a therapeutic target

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TTK/hMPS1 Is an Attractive Therapeutic Target for Triple-Negative Breast Cancer

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Transcriptome Analysis of Wnt3a-Treated Triple-Negative Breast Cancer Cells

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Molecular profiling of patient-derived breast cancer xenografts

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Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons

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HORMAD1 overexpression predicts response to anthracycline–cyclophosphamide and survival in triple‐negative breast cancers

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PARP Inhibition Increases the Response to Chemotherapy in Uveal Melanoma

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Patient Derived Xenografts (PDX) Models as an Avatar to Assess Personalized Therapy Options in Uveal Melanoma: A Feasibility Study

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HRAS is a therapeutic target in malignant chemo-resistant adenomyoepithelioma of the breast

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Prospective, multicenter French study evaluating the clinical impact of the Breast Cancer Intrinsic Subtype-Prosigna® Test in the management of early-stage breast cancers

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Evaluation of methods for amplification of picogram amounts of total RNA for whole genome expression profiling

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A computational method for prioritizing targeted therapies in precision oncology: performance analysis in the SHIVA01 trial

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Characterization of Breast Cancer Preclinical Models Reveals a Specific Pattern of Macrophage Polarization

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The Huntington disease protein accelerates breast tumour development and metastasis through ErbB2/HER2 signalling

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Genomic Instability: A Stronger Prognostic Marker Than Proliferation for Early Stage Luminal Breast Carcinomas

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Respective Prognostic Value of Genomic Grade and Histological Proliferation Markers in Early Stage (pN0) Breast Carcinoma

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Importance of pre-analytical steps for transcriptome and RT-qPCR analyses in the context of the phase II randomised multicentre trial REMAGUS02 of neoadjuvant chemotherapy in breast cancer patients

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A genomic and transcriptomic approach for a differential diagnosis between primary and secondary ovarian carcinomas in patients with a previous history of breast cancer

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