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The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulatio...

The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulatio...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6551226

The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist

About this item

Full title

The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2019-06, Vol.51 (6), p.1024-1034

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The mouse X-inactivation center (
Xic
) locus represents a powerful model for understanding the links between genome architecture and gene regulation, with the non-coding genes
Xist
and
Tsix
showing opposite developmental expression patterns while being organized as an overlapping sense/antisense unit. The
Xic
is organized i...

Alternative Titles

Full title

The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6551226

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6551226

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/s41588-019-0412-0

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