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ArticlesPeer ReviewedFull Text
Macrophage activation syndrome in the era of biologic therapy
Author / Creator:Grom, Alexei A. ; Horne, AnnaCarin ; De Benedetti, Fabrizio
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Rheumatology, 2016-05, Vol.12 (5), p.259-268
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Whole-Exome Sequencing Reveals Mutations in Genes Linked to Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome in Fatal Cases of H1N1 Influenza
Author / Creator:Schulert, Grant S. ; Zhang, Mingce ; Fall, Ndate ; Husami, Ammar ; Kissell, Diane ; Hanosh, Andrew ; Zhang, Kejian ; Davis, Kristina ; Jentzen, Jeffrey M. ; Napolitano, Lena ; Siddiqui, Javed ; Smith, Lauren B. ; Harms, Paul W. ; Grom, Alexei A. ; Cron, Randy Q.
Publisher:United States: Oxford University Press
Journal title:The Journal of infectious diseases, 2016-04, Vol.213 (7), p.1180-1188
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The 4th NextGen therapies for SJIA and MAS: part 3 clinical trials in refractory SJIA: historic controls as an alternative to a withdrawal design study
Author / Creator:de Benedetti, Fabrizio ; Grom, Alexei A. ; Brunner, Hermine
Publisher:London: BioMed Central Ltd
Journal title:Pediatric Rheumatology, 2024-01, Vol.21 (Suppl 1), p.1-4, Article 150
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Urine S100 proteins as potential biomarkers of lupus nephritis activity
Author / Creator:Turnier, Jessica L ; Fall, Ndate ; Thornton, Sherry ; Witte, David ; Bennett, Michael R ; Appenzeller, Simone ; Klein-Gitelman, Marisa S ; Grom, Alexei A ; Brunner, Hermine I
Publisher:England: BioMed Central Ltd
Journal title:Arthritis research & therapy, 2017-10, Vol.19 (1), p.242-242, Article 242
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Population-level single-cell genomics reveals conserved gene programs in systemic juvenile idiopathic arthritis
Author / Creator:Verweyen, Emely L ; Thakkar, Kairavee ; Dhakal, Sanjeev ; Baker, Elizabeth ; Chetal, Kashish ; Schnell, Daniel ; Canna, Scott ; Grom, Alexei A ; Salomonis, Nathan ; Schulert, Grant S
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2023-11, Vol.133 (22), p.1-18
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The 4th NextGen therapies for SJIA and MAS: part 2 phenotypes of refractory SJIA and the landscape for clinical trials in refractory SJIA
Author / Creator:Schulert, Grant ; Vastert, Sebastiaan J ; Grom, Alexei A
Publisher:England: BioMed Central Ltd
Journal title:Pediatric Rheumatology, 2024-01, Vol.21 (Suppl 1), p.87-5, Article 87
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S100 proteins as potential predictive biomarkers of abatacept response in polyarticular juvenile idiopathic arthritis
Author / Creator:Brunner, Hermine I ; Schulert, Grant S ; Sproles, Alyssa ; Thornton, Sherry ; Cornejo, Gabriel Vega ; Antón, Jordi ; Cuttica, Ruben ; Henrickson, Michael ; Foeldvari, Ivan ; Kingsbury, Daniel J ; Askelson, Margarita ; Liu, Jinqi ; Mukherjee, Sumanta ; Wong, Robert L ; Lovell, Daniel J ; Martini, Alberto ; Ruperto, Nicolino ; Grom, Alexei A
Publisher:England: BioMed Central Ltd
Journal title:Arthritis research & therapy, 2024-06, Vol.26 (1), p.125-12, Article 125
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Lack of HLH in FMF
Author / Creator:Basaran, Ozge ; Sag, Erdal ; Aydın, Elif Arslanoglu ; Aydın, Busra ; Tasdemir, Nur Kübra ; Celikel, Elif ; Bayındır, Yagmur ; Özdel, Semanur ; Bilginer, Yelda ; Grom, Alexei A ; Ozen, Seza
Publisher:England: BioMed Central Ltd
Journal title:Pediatric rheumatology online journal, 2025-02, Vol.23 (1), p.14-6, Article 14
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The use of S100 proteins testing in juvenile idiopathic arthritis and autoinflammatory diseases in a pediatric clinical setting: a retrospective analysis
Author / Creator:Aljaberi, Najla ; Tronconi, Elena ; Schulert, Grant ; Grom, Alexei A ; Lovell, Daniel J ; Huggins, Jennifer L ; Henrickson, Michael ; Brunner, Hermine I
Publisher:England: BioMed Central Ltd
Journal title:Pediatric Rheumatology, 2020-01, Vol.18 (1), p.7-7, Article 7
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Part 5: Allogeneic HSCT in refractory SJIA with lung disease; recent cases from centers in North America & Europe
Author / Creator:Grom, Alexei A ; Canna, Scott W ; Abu-Arja, Rolla F ; Sinha, Rashmi ; Peixoto, Luciana ; Cannizzaro, Elvira ; Chandrakasan, Shanmuganathan ; Driest, Kyla ; Marsh, Rebecca ; Neven, Bénédicte ; Onel, Karen ; Prahalad, Sampath ; Prockop, Susan ; Quartier, Pierre ; Roth, Johannes ; Schulert, Grant ; Silva, Juliana M F ; Wall, Donna ; Zeilhofer, Ulrike
Publisher:England: BioMed Central Ltd
Journal title:Pediatric Rheumatology, 2024-01, Vol.21 (Suppl 1), p.86-13, Article 86
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Reasons for canakinumab initiation among patients with periodic fever syndromes: a retrospective medical chart review from the United States
Author / Creator:Hur, Peter ; Lomax, Kathleen G ; Ionescu-Ittu, Raluca ; Manceur, Ameur M ; Xie, Jipan ; Cammarota, Jordan ; Gautam, Raju ; Sanghera, Navneet ; Kim, Nina ; Grom, Alexei A
Publisher:England: BioMed Central Ltd
Journal title:Pediatric Rheumatology, 2021-09, Vol.19 (1), p.143-143, Article 143
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Proceedings from the 4th NextGen Therapies for SJIA and MAS virtual symposium held February 13–14, 2022
Author / Creator:Sinha, Rashmi ; De Benedetti, Fabrizio ; Grom, Alexei A. ; Abu-Arja, Rolla F. ; Behrens, Edward ; Brunner, Hermine ; Canna, Scott W. ; Cannizzaro, Elvira ; Chandrakasan, Shanmuganathan ; Cron, Randy ; Driest, Kyla ; Kimura, Yukiko ; Leptak, Christopher ; Lovell, Daniel J. ; Marsh, Rebecca ; Neven, Bénédicte ; Nigrovic, Peter A. ; Nikolov, Nikolay ; Onel, Karen ; Prahalad, Sampath ; Prockop, Susan ; Quartier, Pierre ; Roth, Johannes ; Schulert, Grant ; Silva, Juliana M. F. ; Vastert, Sebastiaan J. ; Wall, Donna ; Zeilhofer, Ulrike ; Acevedo, Pauline ; Bachrach, Ronny ; Bogg, Laura ; Bush, Leah ; Carlson, Anna ; Culicchia, Cappy ; Cupp, Kari ; Delgaizo, Vincent ; Martinez, Zulayka ; Minerva, Regina ; Peixoto, Luciana ; Rivera, Robyn ; Tronsdal, Sarah
Publisher:London: BioMed Central Ltd
Journal title:Pediatric Rheumatology, 2024-01, Vol.21 (Suppl 1), p.1-4, Article 91
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Targeting interferon-γ in hyperinflammation: opportunities and challenges
Author / Creator:De Benedetti, Fabrizio ; Prencipe, Giusi ; Bracaglia, Claudia ; Marasco, Emiliano ; Grom, Alexei A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Rheumatology, 2021-11, Vol.17 (11), p.678-691
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Pathogenesis of systemic juvenile idiopathic arthritis: some answers, more questions
Author / Creator:Mellins, Elizabeth D. ; Macaubas, Claudia ; Grom, Alexei A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Rheumatology, 2011-07, Vol.7 (7), p.416-426
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Elevated circulating levels of interferon-γ and interferon-γ-induced chemokines characterise patients with macrophage activation syndrome complicating systemic juvenile idiopathic arthritis
Author / Creator:Bracaglia, Claudia ; de Graaf, Kathy ; Pires Marafon, Denise ; Guilhot, Florence ; Ferlin, Walter ; Prencipe, Giusi ; Caiello, Ivan ; Davì, Sergio ; Schulert, Grant ; Ravelli, Angelo ; Grom, Alexei A ; de Min, Cristina ; De Benedetti, Fabrizio
Publisher:England
Journal title:Annals of the rheumatic diseases, 2017-01, Vol.76 (1), p.166-172
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Immature cell populations and an erythropoiesis gene-expression signature in systemic juvenile idiopathic arthritis: implications for pathogenesis
Author / Creator:Hinze, Claas H ; Fall, Ndate ; Thornton, Sherry ; Mo, Jun Q ; Aronow, Bruce J ; Layh-Schmitt, Gerlinde ; Griffin, Thomas A ; Thompson, Susan D ; Colbert, Robert A ; Glass, David N ; Barnes, Michael G ; Grom, Alexei A
Publisher:England: BioMed Central Ltd
Journal title:Arthritis research & therapy, 2010-01, Vol.12 (3), p.R123-R123, Article R123
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Efficacy and safety of emapalumab in macrophage activation syndrome
Author / Creator:De Benedetti, Fabrizio ; Grom, Alexei A ; Brogan, Paul A ; Bracaglia, Claudia ; Pardeo, Manuela ; Marucci, Giulia ; Eleftheriou, Despina ; Papadopoulou, Charalampia ; Schulert, Grant S ; Quartier, Pierre ; Antón, Jordi ; Laveille, Christian ; Frederiksen, Rikke ; Asnaghi, Veronica ; Ballabio, Maria ; Jacqmin, Philippe ; de Min, Cristina
Publisher:England: BMJ Publishing Group Ltd and European League Against Rheumatism
Journal title:Annals of the rheumatic diseases, 2023-06, Vol.82 (6), p.857-865
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Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases
Author / Creator:de Jesus, Adriana A ; Hou, Yangfeng ; Brooks, Stephen ; Malle, Louise ; Biancotto, Angelique ; Huang, Yan ; Calvo, Katherine R ; Marrero, Bernadette ; Moir, Susan ; Oler, Andrew J ; Deng, Zuoming ; Montealegre Sanchez, Gina A ; Ahmed, Amina ; Allenspach, Eric ; Arabshahi, Bita ; Behrens, Edward ; Benseler, Susanne ; Bezrodnik, Liliana ; Bout-Tabaku, Sharon ; Brescia, AnneMarie C ; Brown, Diane ; Burnham, Jon M ; Caldirola, Maria Soledad ; Carrasco, Ruy ; Chan, Alice Y ; Cimaz, Rolando ; Dancey, Paul ; Dare, Jason ; DeGuzman, Marietta ; Dimitriades, Victoria ; Ferguson, Ian ; Ferguson, Polly ; Finn, Laura ; Gattorno, Marco ; Grom, Alexei A ; Hanson, Eric P ; Hashkes, Philip J ; Hedrich, Christian M ; Herzog, Ronit ; Horneff, Gerd ; Jerath, Rita ; Kessler, Elizabeth ; Kim, Hanna ; Kingsbury, Daniel J ; Laxer, Ronald M ; Lee, Pui Y ; Lee-Kirsch, Min Ae ; Lewandowski, Laura ; Li, Suzanne ; Lilleby, Vibke ; Mammadova, Vafa ; Moorthy, Lakshmi N ; Nasrullayeva, Gulnara ; O'Neil, Kathleen M ; Onel, Karen ; Ozen, Seza ; Pan, Nancy ; Pillet, Pascal ; Piotto, Daniela Gp ; Punaro, Marilynn G ; Reiff, Andreas ; Reinhardt, Adam ; Rider, Lisa G ; Rivas-Chacon, Rafael ; Ronis, Tova ; Rösen-Wolff, Angela ; Roth, Johannes ; Ruth, Natasha Mckerran ; Rygg, Marite ; Schmeling, Heinrike ; Schulert, Grant ; Scott, Christiaan ; Seminario, Gisella ; Shulman, Andrew ; Sivaraman, Vidya ; Son, Mary Beth ; Stepanovskiy, Yuriy ; Stringer, Elizabeth ; Taber, Sara ; Terreri, Maria Teresa ; Tifft, Cynthia ; Torgerson, Troy ; Tosi, Laura ; Van Royen-Kerkhof, Annet ; Wampler Muskardin, Theresa ; Canna, Scott W ; Goldbach-Mansky, Raphaela
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2020-04, Vol.130 (4), p.1669-1682
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ArticlesPeer ReviewedFull Text
Diagnosis and Management of the Systemic Juvenile Idiopathic Arthritis Patient with Emerging Lung Disease
Author / Creator:Towe, Christopher ; Grom, Alexei A. ; Schulert, Grant S.
Publisher:Cham: Springer International Publishing
Journal title:Paediatric drugs, 2023-11, Vol.25 (6), p.649-658
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2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis: A European League Against Rheumatism/American College of Rheumatology/Paediatric Rh...
Author / Creator:Ravelli, Angelo ; Minoia, Francesca ; Davì, Sergio ; Horne, AnnaCarin ; Bovis, Francesca ; Pistorio, Angela ; Aricò, Maurizio ; Avcin, Tadej ; Behrens, Edward M ; De Benedetti, Fabrizio ; Filipovic, Lisa ; Grom, Alexei A ; Henter, Jan-Inge ; Ilowite, Norman T ; Jordan, Michael B ; Khubchandani, Raju ; Kitoh, Toshiyuki ; Lehmberg, Kai ; Lovell, Daniel J ; Miettunen, Paivi ; Nichols, Kim E ; Ozen, Seza ; Pachlopnik Schmid, Jana ; Ramanan, Athimalaipet V ; Russo, Ricardo ; Schneider, Rayfel ; Sterba, Gary ; Uziel, Yosef ; Wallace, Carol ; Wouters, Carine ; Wulffraat, Nico ; Demirkaya, Erkan ; Brunner, Hermine I ; Martini, Alberto ; Ruperto, Nicolino ; Cron, Randy Q
Publisher:England
Journal title:Annals of the rheumatic diseases, 2016-03, Vol.75 (3), p.481-489
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Macrophage activation syndrome in the era of biologic therapy

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Whole-Exome Sequencing Reveals Mutations in Genes Linked to Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome in Fatal Cases of H1N1 Influenza

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The 4th NextGen therapies for SJIA and MAS: part 3 clinical trials in refractory SJIA: historic controls as an alternative to a withdrawal design study

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Urine S100 proteins as potential biomarkers of lupus nephritis activity

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Population-level single-cell genomics reveals conserved gene programs in systemic juvenile idiopathic arthritis

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The 4th NextGen therapies for SJIA and MAS: part 2 phenotypes of refractory SJIA and the landscape for clinical trials in refractory SJIA

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S100 proteins as potential predictive biomarkers of abatacept response in polyarticular juvenile idiopathic arthritis

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Lack of HLH in FMF

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The use of S100 proteins testing in juvenile idiopathic arthritis and autoinflammatory diseases in a pediatric clinical setting: a retrospective analysis

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Part 5: Allogeneic HSCT in refractory SJIA with lung disease; recent cases from centers in North America & Europe

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Reasons for canakinumab initiation among patients with periodic fever syndromes: a retrospective medical chart review from the United States

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Proceedings from the 4th NextGen Therapies for SJIA and MAS virtual symposium held February 13–14, 2022

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Targeting interferon-γ in hyperinflammation: opportunities and challenges

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Pathogenesis of systemic juvenile idiopathic arthritis: some answers, more questions

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Elevated circulating levels of interferon-γ and interferon-γ-induced chemokines characterise patients with macrophage activation syndrome complicating systemic juvenile idiopathic arthritis

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Immature cell populations and an erythropoiesis gene-expression signature in systemic juvenile idiopathic arthritis: implications for pathogenesis

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Efficacy and safety of emapalumab in macrophage activation syndrome

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Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases

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Diagnosis and Management of the Systemic Juvenile Idiopathic Arthritis Patient with Emerging Lung Disease

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2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis: A European League Against Rheumatism/American College of Rheumatology/Paediatric Rh...

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