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Macrophage activation syndrome in the era of biologic therapy

Macrophage activation syndrome in the era of biologic therapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_506325

Macrophage activation syndrome in the era of biologic therapy

About this item

Full title

Macrophage activation syndrome in the era of biologic therapy

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Rheumatology, 2016-05, Vol.12 (5), p.259-268

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Key Points
A 'cytokine storm' is the final pathophysiological pathway in macrophage activation syndrome (MAS), and blocking various cytokines could be an attractive therapeutic strategy
Standard doses of anti-IL-1 and anti-IL-6 biologic therapies do not have a major effect on MAS rates even if the underlying disease responds well to the treat...

Alternative Titles

Full title

Macrophage activation syndrome in the era of biologic therapy

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_506325

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_506325

Other Identifiers

ISSN

1759-4790

E-ISSN

1759-4804

DOI

10.1038/nrrheum.2015.179

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