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ArticlesPeer ReviewedFull Text
Teclistamab: Mechanism of action, clinical, and translational science
Author / Creator:Guo, Yue ; Quijano Cardé, Natalia A. ; Kang, Lijuan ; Verona, Raluca ; Banerjee, Arnob ; Kobos, Rachel ; Chastain, Katherine ; Uhlar, Clarissa ; Pillarisetti, Kodandaram ; Doyle, Margaret ; Smit, Jennifer ; Haddish‐Berhane, Nahor ; Ouellet, Daniele
Publisher:United States: John Wiley & Sons, Inc
Journal title:Clinical and translational science, 2024-01, Vol.17 (1), p.e13717-n/a
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ArticlesPeer ReviewedFull Text
Optimization of clinical dosing schedule to manage neutropenia: learnings from semi-mechanistic modeling simulation approach
Author / Creator:Guo, Yue ; Haddish-Berhane, Nahor ; Xie, Hong ; Ouellet, Daniele
Publisher:New York: Springer US
Journal title:Journal of pharmacokinetics and pharmacodynamics, 2020-02, Vol.47 (1), p.47-58
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On translation of antibody drug conjugates efficacy from mouse experimental tumors to the clinic: a PK/PD approach
Author / Creator:Haddish-Berhane, Nahor ; Shah, Dhaval K. ; Ma, Dangshe ; Leal, Mauricio ; Gerber, Hans-Peter ; Sapra, Puja ; Barton, Hugh A. ; Betts, Alison M.
Publisher:Boston: Springer US
Journal title:Journal of pharmacokinetics and pharmacodynamics, 2013-10, Vol.40 (5), p.557-571
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Demonstrating Bioequivalence for Two Dose Strengths of Niraparib and Abiraterone Acetate Dual-Action Tablets Versus Single Agents: Utility of Clinical Study Data Supplemented with Modeling and Simulat...
Author / Creator:Yu, Alex ; Hazra, Anasuya ; Jiao, James Juhui ; Hellemans, Peter ; Mitselos, Anna ; Tian, Hui ; Ruixo, Juan Jose Perez ; Haddish-Berhane, Nahor ; Ouellet, Daniele ; Russu, Alberto
Publisher:Cham: Springer International Publishing
Journal title:Clinical pharmacokinetics, 2024-04, Vol.63 (4), p.511-527
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A Translational Quantitative Systems Pharmacology Model for CD3 Bispecific Molecules: Application to Quantify T Cell-Mediated Tumor Cell Killing by P-Cadherin LP DART
Author / Creator:Betts, Alison ; Haddish-Berhane, Nahor ; Shah, Dhaval K. ; van der Graaf, Piet H. ; Barletta, Frank ; King, Lindsay ; Clark, Tracey ; Kamperschroer, Cris ; Root, Adam ; Hooper, Andrea ; Chen, Xiaoying
Publisher:Cham: Springer International Publishing
Journal title:The AAPS journal, 2019-05, Vol.21 (4), p.66, Article 66
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ArticlesPeer ReviewedFull Text
Bench to bedside translation of antibody drug conjugates using a multiscale mechanistic PK/PD model: a case study with brentuximab-vedotin
Author / Creator:Shah, Dhaval K. ; Haddish-Berhane, Nahor ; Betts, Alison
Publisher:Boston: Springer US
Journal title:Journal of pharmacokinetics and pharmacodynamics, 2012-12, Vol.39 (6), p.643-659
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ArticlesPeer ReviewedFull Text
The pH-altering agent omeprazole affects rate but not the extent of ibrutinib exposure
Author / Creator:de Jong, Jan ; Haddish-Berhane, Nahor ; Hellemans, Peter ; Jiao, James ; Sukbuntherng, Juthamas ; Ouellet, Daniele
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer chemotherapy and pharmacology, 2018-08, Vol.82 (2), p.299-308
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ArticlesPeer ReviewedFull Text
A CD3-bispecific molecule targeting P-cadherin demonstrates T cell-mediated regression of established solid tumors in mice
Author / Creator:Fisher, Timothy S. ; Hooper, Andrea T. ; Lucas, Justin ; Clark, Tracey H. ; Rohner, Allison K. ; Peano, Bryan ; Elliott, Mark W. ; Tsaparikos, Konstantinos ; Wang, Hui ; Golas, Jonathan ; Gavriil, Maria ; Haddish-Berhane, Nahor ; Tchistiakova, Lioudmila ; Gerber, Hans-Peter ; Root, Adam R. ; May, Chad
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer Immunology, Immunotherapy, 2018-02, Vol.67 (2), p.247-259
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ArticlesPeer ReviewedFull Text
Establishing in vitro–in vivo correlation for antibody drug conjugate efficacy: a PK/PD modeling approach
Author / Creator:Shah, Dhaval K. ; Loganzo, Frank ; Haddish-Berhane, Nahor ; Musto, Sylvia ; Wald, Hallie S. ; Barletta, Frank ; Lucas, Judy ; Clark, Tracey ; Hansel, Steve ; Betts, Alison
Publisher:New York: Springer US
Journal title:Journal of pharmacokinetics and pharmacodynamics, 2018-04, Vol.45 (2), p.339-349
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ArticlesPeer ReviewedFull Text
Correction to: A Translational Quantitative Systems Pharmacology Model for CD3 Bispecific Molecules: Application to Quantify T Cell-Mediated Tumor Cell Killing by P-Cadherin LP DART
Author / Creator:Betts, Alison ; Haddish-Berhane, Nahor ; Shah, Dhaval K. ; van der Graaf, Piet H. ; Barletta, Frank ; King, Lindsay ; Clark, Tracey ; Kamperschroer, Cris ; Root, Adam ; Hooper, Andrea ; Chen, Xiaoying
Publisher:Cham: Springer International Publishing
Journal title:The AAPS journal, 2019-06, Vol.21 (4), p.73-73, Article 73
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ArticlesPeer ReviewedFull Text
The role of multiscale computational approaches for rational design of conventional and nanoparticle oral drug delivery systems
Author / Creator:Haddish-Berhane, Nahor ; Rickus, Jenna L ; Haghighi, Kamyar
Publisher:New Zealand: Taylor & Francis Ltd
Journal title:International journal of nanomedicine, 2007-01, Vol.2 (3), p.315-331
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Teclistamab: Mechanism of action, clinical, and translational science

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Optimization of clinical dosing schedule to manage neutropenia: learnings from semi-mechanistic modeling simulation approach

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On translation of antibody drug conjugates efficacy from mouse experimental tumors to the clinic: a PK/PD approach

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Demonstrating Bioequivalence for Two Dose Strengths of Niraparib and Abiraterone Acetate Dual-Action Tablets Versus Single Agents: Utility of Clinical Study Data Supplemented with Modeling and Simulat...

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A Translational Quantitative Systems Pharmacology Model for CD3 Bispecific Molecules: Application to Quantify T Cell-Mediated Tumor Cell Killing by P-Cadherin LP DART

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Bench to bedside translation of antibody drug conjugates using a multiscale mechanistic PK/PD model: a case study with brentuximab-vedotin

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The pH-altering agent omeprazole affects rate but not the extent of ibrutinib exposure

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A CD3-bispecific molecule targeting P-cadherin demonstrates T cell-mediated regression of established solid tumors in mice

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Establishing in vitro–in vivo correlation for antibody drug conjugate efficacy: a PK/PD modeling approach

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Correction to: A Translational Quantitative Systems Pharmacology Model for CD3 Bispecific Molecules: Application to Quantify T Cell-Mediated Tumor Cell Killing by P-Cadherin LP DART

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The role of multiscale computational approaches for rational design of conventional and nanoparticle oral drug delivery systems

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