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ArticlesPeer ReviewedFull Text
Afatinib versus gefitinib as first-line treatment of patients with EGFR mutation-positive non-small-cell lung cancer (LUX-Lung 7): a phase 2B, open-label, randomised controlled trial
Author / Creator:Park, Keunchil, Prof ; Tan, Eng-Huat, MD ; O'Byrne, Ken, Prof ; Zhang, Li, Prof ; Boyer, Michael, Prof ; Mok, Tony, Prof ; Hirsh, Vera, Prof ; Yang, James Chih-Hsin, Prof ; Lee, Ki Hyeong, MD ; Lu, Shun, Prof ; Shi, Yuankai, MD ; Kim, Sang-We, MD ; Laskin, Janessa, MD ; Kim, Dong-Wan, Prof ; Arvis, Catherine Dubos, MD ; Kölbeck, Karl, MD ; Laurie, Scott A, MD ; Tsai, Chun-Ming, Prof ; Shahidi, Mehdi, MD ; Kim, Miyoung, MD ; Massey, Dan, PhD ; Zazulina, Victoria, MD ; Paz-Ares, Luis, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2016-05, Vol.17 (5), p.577-589
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Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): analysis of overall survival data from two randomised, phase 3 trials
Author / Creator:Yang, James Chih-Hsin, Prof ; Wu, Yi-Long, Prof ; Schuler, Martin, Prof ; Sebastian, Martin, MD ; Popat, Sanjay, FRCP ; Yamamoto, Nobuyuki, Prof ; Zhou, Caicun, Prof ; Hu, Cheng-Ping, Prof ; O'Byrne, Kenneth, Prof ; Feng, Jifeng, Prof ; Lu, Shun, Prof ; Huang, Yunchao, Prof ; Geater, Sarayut L, MD ; Lee, Kye Young, Prof ; Tsai, Chun-Ming, Prof ; Gorbunova, Vera, Prof ; Hirsh, Vera, Prof ; Bennouna, Jaafar, Prof ; Orlov, Sergey, Prof ; Mok, Tony, Prof ; Boyer, Michael, Prof ; Su, Wu-Chou, Prof ; Lee, Ki Hyeong, Prof ; Kato, Terufumi, MD ; Massey, Dan, MSc ; Shahidi, Mehdi, MD ; Zazulina, Victoria, MD ; Sequist, Lecia V, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2015-02, Vol.16 (2), p.141-151
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Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): a phase 2b/...
Author / Creator:Miller, Vincent A, Prof ; Hirsh, Vera, MD ; Cadranel, Jacques, Prof ; Chen, Yuh-Min, MD ; Park, Keunchil, Prof ; Kim, Sang-We, Prof ; Zhou, Caicun, Prof ; Su, Wu-Chou, Prof ; Wang, Mengzhao, Prof ; Sun, Yan, Prof ; Heo, Dae Seog, Prof ; Crino, Lucio, Prof ; Tan, Eng-Huat, MD ; Chao, Tsu-Yi, Prof ; Shahidi, Mehdi, MD ; Cong, Xiuyu Julie, PhD ; Lorence, Robert M, MD ; Yang, James Chih-Hsin, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2012-05, Vol.13 (5), p.528-538
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ArticlesPeer ReviewedFull Text
Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): a randomised phase III trial
Author / Creator:Kim, Edward S, MD ; Hirsh, Vera, MD ; Mok, Tony, Prof ; Socinski, Mark A, Prof ; Gervais, Radj, MD ; Wu, Yi-Long, Prof ; Li, Long-Yun, Prof ; Watkins, Claire L, MSc ; Sellers, Mark V, MSc ; Lowe, Elizabeth S, MD ; Sun, Yan, MD ; Liao, Mei-Lin, Prof ; Østerlind, Kell, MD ; Reck, Martin, MD ; Armour, Alison A, FRCR ; Shepherd, Frances A, Prof ; Lippman, Scott M, Prof ; Douillard, Jean-Yves, Prof
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2008-11, Vol.372 (9652), p.1809-1818
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ArticlesPeer ReviewedFull Text
EGFR mutation detection in circulating cell-free DNA of lung adenocarcinoma patients: analysis of LUX-Lung 3 and 6
Author / Creator:Wu, Yi-Long ; Sequist, Lecia V ; Hu, Cheng-Ping ; Feng, Jifeng ; Lu, Shun ; Huang, Yunchao ; Li, Wei ; Hou, Mei ; Schuler, Martin ; Mok, Tony ; Yamamoto, Nobuyuki ; O'Byrne, Kenneth ; Hirsh, Vera ; Gibson, Neil ; Massey, Dan ; Kim, Miyoung ; Yang, James Chih-Hsin
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2017-01, Vol.116 (2), p.175-185
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ArticlesPeer ReviewedFull Text
Perspectives in immunotherapy: meeting report from the “Immunotherapy Bridge”, Napoli, November 30th 2016
Author / Creator:Ascierto, Paolo A. ; Daniele, Bruno ; Hammers, Hans ; Hirsh, Vera ; Kim, Joseph ; Licitra, Lisa ; Nanda, Rita ; Pignata, Sandro
Publisher:England: BioMed Central Ltd
Journal title:Journal of translational medicine, 2017-10, Vol.15 (1), p.205-21, Article 205
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ArticlesPeer ReviewedFull Text
Next-Generation Covalent Irreversible Kinase Inhibitors in NSCLC: Focus on Afatinib
Author / Creator:Hirsh, Vera
Publisher:Cham: Springer International Publishing
Journal title:BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy, 2015-06, Vol.29 (3), p.167-183
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ArticlesPeer ReviewedFull Text
Turning EGFR mutation-positive non-small-cell lung cancer into a chronic disease: optimal sequential therapy with EGFR tyrosine kinase inhibitors
Author / Creator:Hirsh, Vera
Publisher:London, England: SAGE Publications
Journal title:Therapeutic advances in medical oncology, 2018-01, Vol.10, p.1758834017753338-1758834017753338
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ArticlesPeer ReviewedFull Text
New developments in the treatment of advanced squamous cell lung cancer: focus on afatinib
Author / Creator:Hirsh, Vera
Publisher:New Zealand: Dove Medical Press Limited
Journal title:OncoTargets and therapy, 2017-01, Vol.10, p.2513-2526
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ArticlesPeer ReviewedFull Text
Afatinib (BIBW 2992) development in non-small-cell lung cancer
Author / Creator:Hirsh, Vera
Publisher:England: Future Medicine Ltd
Journal title:Future oncology (London, England), 2011-07, Vol.7 (7), p.817-825
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ArticlesPeer ReviewedFull Text
nab-paclitaxel for the management of patients with advanced non-small-cell lung cancer
Author / Creator:Hirsh, Vera
Publisher:London: Informa UK, Ltd
Journal title:Expert review of anticancer therapy, 2014-02, Vol.14 (2), p.129-141
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ArticlesPeer ReviewedFull Text
Turning mutation-positive non-small-cell lung cancer into a chronic disease: optimal sequential therapy with EGFR tyrosine kinase inhibitors
Author / Creator:Vera Hirsh
Publisher:SAGE Publishing
Journal title:Therapeutic advances in medical oncology, 2018-01, Vol.10
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ArticlesPeer ReviewedFull Text
Phase II study of two dose schedules of C.E.R.A. (Continuous Erythropoietin Receptor Activator) in anemic patients with advanced non-small cell lung cancer (NSCLC) receiving chemotherapy
Author / Creator:Hirsh, Vera ; Glaspy, John ; Mainwaring, Paul ; Manegold, Christian ; Ramlau, Rodryg ; Eid, Joseph E
Publisher:England: BioMed Central
Journal title:Current controlled trials in cardiovascular medicine, 2007-03, Vol.8 (1), p.8-8, Article 8
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ArticlesPeer ReviewedFull Text
Crizotinib versus Chemotherapy in Advanced ALK-Positive Lung Cancer
Author / Creator:Shaw, Alice T ; Kim, Dong-Wan ; Nakagawa, Kazuhiko ; Seto, Takashi ; Crinó, Lucio ; Ahn, Myung-Ju ; De Pas, Tommaso ; Besse, Benjamin ; Solomon, Benjamin J ; Blackhall, Fiona ; Wu, Yi-Long ; Thomas, Michael ; O'Byrne, Kenneth J ; Moro-Sibilot, Denis ; Camidge, D. Ross ; Mok, Tony ; Hirsh, Vera ; Riely, Gregory J ; Iyer, Shrividya ; Tassell, Vanessa ; Polli, Anna ; Wilner, Keith D ; Jänne, Pasi A
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2013-06, Vol.368 (25), p.2385-2394
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ArticlesPeer ReviewedFull Text
Delaying skeletal-related events in a randomized phase 3 study of denosumab versus zoledronic acid in patients with advanced cancer: an analysis of data from patients with solid tumors
Author / Creator:Henry, David ; Vadhan-Raj, Saroj ; Hirsh, Vera ; von Moos, Roger ; Hungria, Vania ; Costa, Luis ; Woll, Penella J ; Scagliotti, Giorgio ; Smith, Geoffrey ; Feng, Amy ; Jun, Susie ; Dansey, Roger ; Yeh, Howard
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Supportive care in cancer, 2014-03, Vol.22 (3), p.679-687
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ArticlesPeer ReviewedFull Text
Erlotinib in Previously Treated Non–Small-Cell Lung Cancer
Author / Creator:Shepherd, Frances A ; Rodrigues Pereira, José ; Ciuleanu, Tudor ; Tan, Eng Huat ; Hirsh, Vera ; Thongprasert, Sumitra ; Campos, Daniel ; Maoleekoonpiroj, Savitree ; Smylie, Michael ; Martins, Renato ; van Kooten, Maximiliano ; Dediu, Mircea ; Findlay, Brian ; Tu, Dongsheng ; Johnston, Dianne ; Bezjak, Andrea ; Clark, Gary ; Santabárbara, Pedro ; Seymour, Lesley
Publisher:Boston, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2005-07, Vol.353 (2), p.123-132
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Newsletter articlesFull Text
Chemotherapy with 5-fluorouracil and cisplatin or 5-FU, cisplatin, and vinblastine for advanced non-small cell lung cancer
Publisher:NewsRX LLC
Journal title:Cancer Weekly, 1991, p.24
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ArticlesPeer ReviewedFull Text
First-line afatinib vs gefitinib for patients with EGFR mutation-positive NSCLC (LUX-Lung 7): impact of afatinib dose adjustment and analysis of mode of initial progression for patients who continued...
Author / Creator:Schuler, Martin ; Eng-Huat Tan ; Kenneth O’Byrne ; Zhang, Li ; Boyer, Michael ; Mok, Tony ; Hirsh, Vera ; Yang, James Chih-Hsin ; Lee, Ki Hyeong ; Lu, Shun ; Shi, Yuankai ; Sang-We, Kim ; Laskin, Janessa ; Dong-Wan, Kim ; Catherine Dubos Arvis ; Kölbeck, Karl ; Massey, Dan ; Märten, Angela ; Paz-Ares, Luis ; Park, Keunchil
Publisher:Heidelberg: Springer Nature B.V
Journal title:Journal of cancer research and clinical oncology, 2019-06, Vol.145 (6), p.1569-1579
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ArticlesPeer ReviewedFull Text
Metastatic Bone Disease in Patients with Solid Tumors–-Burden of Bone Disease and the Role of Zoledronic Acid
Author / Creator:Hirsh, Vera
Publisher:London, England: SAGE Publications
Journal title:Clinical medicine insights. Therapeutics, 2009-01, Vol.1, p.379
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ArticlesFull Text
Does EGFR Mutation Type Influence Patient-Reported Outcomes in Patients with Advanced EGFR Mutation-Positive Non-Small-Cell Lung Cancer? Analysis of Two Large, Phase III Studies Comparing Afatinib wit...
Author / Creator:Wu, Yi-Long ; Hirsh, Vera ; Sequist, Lecia V. ; Hu, Cheng-Ping ; Feng, Jifeng ; Lu, Shun ; Huang, Yunchao ; Schuler, Martin ; Mok, Tony ; Yamamoto, Nobuyuki ; O’Byrne, Kenneth ; Geater, Sarayut L. ; Zhou, Caicun ; Massey, Dan ; Märten, Angela ; Lungershausen, Juliane ; Yang, James Chih-Hsin
Publisher:Cham: Springer International Publishing
Journal title:The patient : patient-centered outcomes research, 2018-02, Vol.11 (1), p.131-141
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Showing 1 to 20 of 27 results

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Afatinib versus gefitinib as first-line treatment of patients with EGFR mutation-positive non-small-cell lung cancer (LUX-Lung 7): a phase 2B, open-label, randomised controlled trial

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Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): analysis of overall survival data from two randomised, phase 3 trials

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Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): a phase 2b/...

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Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): a randomised phase III trial

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EGFR mutation detection in circulating cell-free DNA of lung adenocarcinoma patients: analysis of LUX-Lung 3 and 6

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Perspectives in immunotherapy: meeting report from the “Immunotherapy Bridge”, Napoli, November 30th 2016

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Next-Generation Covalent Irreversible Kinase Inhibitors in NSCLC: Focus on Afatinib

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Turning EGFR mutation-positive non-small-cell lung cancer into a chronic disease: optimal sequential therapy with EGFR tyrosine kinase inhibitors

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New developments in the treatment of advanced squamous cell lung cancer: focus on afatinib

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Afatinib (BIBW 2992) development in non-small-cell lung cancer

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nab-paclitaxel for the management of patients with advanced non-small-cell lung cancer

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Turning mutation-positive non-small-cell lung cancer into a chronic disease: optimal sequential therapy with EGFR tyrosine kinase inhibitors

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Phase II study of two dose schedules of C.E.R.A. (Continuous Erythropoietin Receptor Activator) in anemic patients with advanced non-small cell lung cancer (NSCLC) receiving chemotherapy

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Crizotinib versus Chemotherapy in Advanced ALK-Positive Lung Cancer

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Delaying skeletal-related events in a randomized phase 3 study of denosumab versus zoledronic acid in patients with advanced cancer: an analysis of data from patients with solid tumors

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Erlotinib in Previously Treated Non–Small-Cell Lung Cancer

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Chemotherapy with 5-fluorouracil and cisplatin or 5-FU, cisplatin, and vinblastine for advanced non-small cell lung cancer

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First-line afatinib vs gefitinib for patients with EGFR mutation-positive NSCLC (LUX-Lung 7): impact of afatinib dose adjustment and analysis of mode of initial progression for patients who continued...

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Metastatic Bone Disease in Patients with Solid Tumors–-Burden of Bone Disease and the Role of Zoledronic Acid

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Does EGFR Mutation Type Influence Patient-Reported Outcomes in Patients with Advanced EGFR Mutation-Positive Non-Small-Cell Lung Cancer? Analysis of Two Large, Phase III Studies Comparing Afatinib wit...

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