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167 results for Histone-Lysine+N-Methyltransferase+-+chemistry

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ArticlesPeer ReviewedFull Text
The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia
Author / Creator:Issa, Ghayas C. ; Aldoss, Ibrahim ; DiPersio, John ; Cuglievan, Branko ; Stone, Richard ; Arellano, Martha ; Thirman, Michael J. ; Patel, Manish R. ; Dickens, David S. ; Shenoy, Shalini ; Shukla, Neerav ; Kantarjian, Hagop ; Armstrong, Scott A. ; Perner, Florian ; Perry, Jennifer A. ; Rosen, Galit ; Bagley, Rebecca G. ; Meyers, Michael L. ; Ordentlich, Peter ; Gu, Yu ; Kumar, Vinit ; Smith, Steven ; McGeehan, Gerard M. ; Stein, Eytan M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2023-03, Vol.615 (7954), p.920-924
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The language of chromatin modification in human cancers
Author / Creator:Zhao, Shuai ; Allis, C. David ; Wang, Gang Greg
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2021-07, Vol.21 (7), p.413-430
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Hijacked in cancer: the KMT2 (MLL) family of methyltransferases
Author / Creator:Rao, Rajesh C. ; Dou, Yali
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2015-06, Vol.15 (6), p.334-346
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The Polycomb complex PRC2 and its mark in life
Author / Creator:Margueron, Raphaël ; Reinberg, Danny
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2011-01, Vol.469 (7330), p.343-349
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N+-C-H···O Hydrogen bonds in protein-ligand complexes
Author / Creator:Itoh, Yukihiro ; Nakashima, Yusuke ; Tsukamoto, Shuichiro ; Kurohara, Takashi ; Suzuki, Miki ; Sakae, Yoshitake ; Oda, Masayuki ; Okamoto, Yuko ; Suzuki, Takayoshi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-01, Vol.9 (1), p.767-767, Article 767
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Structural basis of nucleosome recognition and modification by MLL methyltransferases
Author / Creator:Xue, Han ; Yao, Tonghui ; Cao, Mi ; Zhu, Guanjun ; Li, Yan ; Yuan, Guiyong ; Chen, Yong ; Lei, Ming ; Huang, Jing
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-09, Vol.573 (7774), p.445-449
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ATX3, ATX4, and ATX5 Encode Putative H3K4 Methyltransferases and Are Critical for Plant Development
Author / Creator:Chen, Li-Qun ; Luo, Jin-Hong ; Cui, Zhen-Hai ; Xue, Ming ; Wang, Li ; Zhang, Xiao-Yu ; Pawlowski, Wojciech P. ; He, Yan
Publisher:United States: American Society of Plant Biologists
Journal title:Plant physiology (Bethesda), 2017-07, Vol.174 (3), p.1795-1806
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Re-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice
Author / Creator:Davies, Benjamin ; Hatton, Edouard ; Altemose, Nicolas ; Hussin, Julie G. ; Pratto, Florencia ; Zhang, Gang ; Hinch, Anjali Gupta ; Moralli, Daniela ; Biggs, Daniel ; Diaz, Rebeca ; Preece, Chris ; Li, Ran ; Bitoun, Emmanuelle ; Brick, Kevin ; Green, Catherine M. ; Camerini-Otero, R. Daniel ; Myers, Simon R. ; Donnelly, Peter
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-02, Vol.530 (7589), p.171-176
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Structural basis for activity regulation of MLL family methyltransferases
Author / Creator:Li, Yanjing ; Han, Jianming ; Zhang, Yuebin ; Cao, Fang ; Liu, Zhijun ; Li, Shuai ; Wu, Jian ; Hu, Chunyi ; Wang, Yan ; Shuai, Jin ; Chen, Juan ; Cao, Liaoran ; Li, Dangsheng ; Shi, Pan ; Tian, Changlin ; Zhang, Jian ; Dou, Yali ; Li, Guohui ; Chen, Yong ; Lei, Ming
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-02, Vol.530 (7591), p.447-452
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Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation
Author / Creator:Li, Xueqin ; Harris, C. Jake ; Zhong, Zhenhui ; Chen, Wei ; Liu, Rui ; Jia, Bei ; Wang, Zonghua ; Li, Sisi ; Jacobsen, Steven E. ; Du, Jiamu
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-09, Vol.115 (37), p.E8793-E8802
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MLL2 conveys transcription-independent H3K4 trimethylation in oocytes
Author / Creator:Hanna, Courtney W. ; Taudt, Aaron ; Huang, Jiahao ; Gahurova, Lenka ; Kranz, Andrea ; Andrews, Simon ; Dean, Wendy ; Stewart, A. Francis ; Colomé-Tatché, Maria ; Kelsey, Gavin
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2018-01, Vol.25 (1), p.73-82
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SRA- and SET-domain-containing proteins link RNA polymerase V occupancy to DNA methylation
Author / Creator:Johnson, Lianna M. ; Du, Jiamu ; Hale, Christopher J. ; Bischof, Sylvain ; Feng, Suhua ; Chodavarapu, Ramakrishna K. ; Zhong, Xuehua ; Marson, Giuseppe ; Pellegrini, Matteo ; Segal, David J. ; Patel, Dinshaw J. ; Jacobsen, Steven E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2014-03, Vol.507 (7490), p.124-128
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Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)
Author / Creator:McCabe, Michael T ; Graves, Alan P ; Ganji, Gopinath ; Diaz, Elsie ; Halsey, Wendy S ; Jiang, Yong ; Smitheman, Kimberly N ; Ott, Heidi M ; Pappalardi, Melissa B ; Allen, Kimberly E ; Chen, Stephanie B ; Della Pietra, Anthony III ; Dul, Edward ; Hughes, Ashley M ; Gilbert, Seth A ; Thrall, Sara H ; Tummino, Peter J ; Kruger, Ryan G ; Brandt, Martin ; Schwartz, Benjamin ; Creasy, Caretha L
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (8), p.2989-2994
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Drive Against Hotspot Motifs in Primates Implicates the PRDM9 Gene in Meiotic Recombination
Author / Creator:Myers, Simon ; Bowden, Rory ; Tumian, Afidalina ; Bontrop, Ronald E ; Freeman, Colin ; MacFie, Tammie S ; McVean, Gil ; Donnelly, Peter
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2010-02, Vol.327 (5967), p.876-879
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Shaping the cellular landscape with Set2/SETD2 methylation
Author / Creator:McDaniel, Stephen L. ; Strahl, Brian D.
Publisher:Cham: Springer International Publishing
Journal title:Cellular and molecular life sciences : CMLS, 2017-09, Vol.74 (18), p.3317-3334
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Role of the polycomb protein EED in the propagation of repressive histone marks
Author / Creator:Margueron, Raphael ; Justin, Neil ; Ohno, Katsuhito ; Sharpe, Miriam L. ; Son, Jinsook ; Drury III, William J. ; Voigt, Philipp ; Martin, Stephen R. ; Taylor, William R. ; De Marco, Valeria ; Pirrotta, Vincenzo ; Reinberg, Danny ; Gamblin, Steven J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2009-10, Vol.461 (7265), p.762-767
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Symmetric dimethylation of H3R2 is a newly identified histone mark that supports euchromatin maintenance
Author / Creator:Migliori, Valentina ; Müller, Julius ; Phalke, Sameer ; Low, Diana ; Bezzi, Marco ; Mok, Wei Chuen ; Sahu, Sanjeeb Kumar ; Gunaratne, Jayantha ; Capasso, Paola ; Bassi, Christian ; Cecatiello, Valentina ; De Marco, Ario ; Blackstock, Walter ; Kuznetsov, Vladimir ; Amati, Bruno ; Mapelli, Marina ; Guccione, Ernesto
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2012-02, Vol.19 (2), p.136-144
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PRDM9 Is a Major Determinant of Meiotic Recombination Hotspots in Humans and Mice
Author / Creator:Baudat, F ; Buard, J ; Grey, C ; Fledel-Alon, A ; Ober, C ; Przeworski, M ; Coop, G ; de Massy, B
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2010-02, Vol.327 (5967), p.836-840
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WDR5 modulates cell motility and morphology and controls nuclear changes induced by a 3D environment
Author / Creator:Wang, Pengbo ; Dreger, Marcel ; Madrazo, Elena ; Williams, Craig J. ; Samaniego, Rafael ; Hodson, Nigel W. ; Monroy, Francisco ; Baena, Esther ; Sánchez-Mateos, Paloma ; Hurlstone, Adam ; Redondo-Muñoz, Javier
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-08, Vol.115 (34), p.8581-8586
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The diverse functions of histone lysine methylation
Author / Creator:Martin, Cyrus ; Zhang, Yi
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Molecular cell biology, 2005-11, Vol.6 (11), p.838-849
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The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia

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The language of chromatin modification in human cancers

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Hijacked in cancer: the KMT2 (MLL) family of methyltransferases

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The Polycomb complex PRC2 and its mark in life

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N+-C-H···O Hydrogen bonds in protein-ligand complexes

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Structural basis of nucleosome recognition and modification by MLL methyltransferases

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ATX3, ATX4, and ATX5 Encode Putative H3K4 Methyltransferases and Are Critical for Plant Development

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Re-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice

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Structural basis for activity regulation of MLL family methyltransferases

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Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation

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MLL2 conveys transcription-independent H3K4 trimethylation in oocytes

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SRA- and SET-domain-containing proteins link RNA polymerase V occupancy to DNA methylation

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Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)

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Drive Against Hotspot Motifs in Primates Implicates the PRDM9 Gene in Meiotic Recombination

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Shaping the cellular landscape with Set2/SETD2 methylation

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Role of the polycomb protein EED in the propagation of repressive histone marks

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Symmetric dimethylation of H3R2 is a newly identified histone mark that supports euchromatin maintenance

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PRDM9 Is a Major Determinant of Meiotic Recombination Hotspots in Humans and Mice

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WDR5 modulates cell motility and morphology and controls nuclear changes induced by a 3D environment

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The diverse functions of histone lysine methylation

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