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ArticlesPeer ReviewedFull Text
Oral trehalose improves histological and behavior symptoms of mucopolysaccharidosis type II in iduronate 2-sulfatase deficient mice
Author / Creator:Lee, Hyesook ; Han, Jung-Hwa ; Jeong, Roo Gam ; Kang, Yun Jeong ; Choi, Byung Hyun ; Kim, Seo Rin ; Cheon, Chong Kun ; Hur, Jin ; Lee, Soo Yong
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-02, Vol.15 (1), p.4882-12
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In vivo brain delivery of BBB-enabled iduronate 2-sulfatase in rats
Author / Creator:Costain, Will J. ; Haqqani, Arsalan S. ; Hussack, Greg ; van Faassen, Henk ; Lessard, Etienne ; Ling, Binbing ; Brunette, Eric ; Ly, Dao ; Fang, Hung ; Bultinck, Jennyfer ; Geysens, Steven ; Pynaert, Gwenda ; Piens, Kathleen ; Ryckaert, Stefan ; Fudalej, Franck ; Vervecken, Wouter ; Stanimirovic, Danica
Publisher:England: BioMed Central Ltd
Journal title:Fluids and barriers of the CNS, 2025-01, Vol.22 (1), p.7-13, Article 7
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ArticlesPeer ReviewedFull Text
Characterization of a HIR-Fab-IDS, Novel Iduronate 2-Sulfatase Fusion Protein for the Treatment of Neuropathic Mucopolysaccharidosis Type II (Hunter Syndrome)
Author / Creator:Gusarova, Valentina D. ; Smolov, Maxim A. ; Lyagoskin, Ivan V. ; Degterev, Maksim B. ; Rechetnik, Elizaveta V. ; Rodionov, Alexander V. ; Pantyushenko, Marina S. ; Shukurov, Rahim R.
Publisher:Cham: Springer International Publishing
Journal title:BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy, 2023-05, Vol.37 (3), p.375-395
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ArticlesPeer ReviewedFull Text
Shutdown of ER-associated degradation pathway rescues functions of mutant iduronate 2-sulfatase linked to mucopolysaccharidosis type II
Author / Creator:Osaki, Yosuke ; Saito, Atsushi ; Kanemoto, Soshi ; Kaneko, Masayuki ; Matsuhisa, Koji ; Asada, Rie ; Masaki, Takao ; Orii, Kenji ; Fukao, Toshiyuki ; Tomatsu, Shunji ; Imaizumi, Kazunori
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2018-07, Vol.9 (8), p.808-14, Article 808
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Novel variations in Exon 4 of the iduronate 2-sulfatase gene in six Indonesian patients with mucopolysaccharidosis type II
Author / Creator:Purwanto, M F ; Priambodo, R ; Ariani, Y ; Pangestika, Y ; Hafifah, C N ; Bowolaksono, A ; Sjarif, D R
Publisher:Bristol: IOP Publishing
Journal title:Journal of physics. Conference series, 2018-08, Vol.1073 (3), p.32070
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Comparative studies of vertebrate iduronate 2-sulfatase (IDS) genes and proteins: evolution of A mammalian X-linked gene
Author / Creator:Holmes, Roger S.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:3 Biotech, 2017-05, Vol.7 (1), p.22-10, Article 22
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724. Alternative Splicing of the Human Iduronate 2-Sulfatase Gene and Implications in Gene Therapy
Publisher:Elsevier Inc
Journal title:Molecular therapy, 2011-05, Vol.19, p.S276-S276
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Glycosaminoglycan signatures in body fluids of mucopolysaccharidosis type II mouse model under long-term enzyme replacement therapy
Author / Creator:Maccari, Francesca ; Rigon, Laura ; Mantovani, Veronica ; Galeotti, Fabio ; Salvalaio, Marika ; D’Avanzo, Francesca ; Zanetti, Alessandra ; Capitani, Federica ; Gabrielli, Orazio ; Tomanin, Rosella ; Volpi, Nicola
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Journal of molecular medicine (Berlin, Germany), 2022-08, Vol.100 (8), p.1169-1179
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Molecular basis of mucopolysaccharidosis type II (Hunter syndrome): first review and classification of published IDS gene variants
Author / Creator:Zanetti, Alessandra ; D’Avanzo, Francesca ; Tomanin, Rosella
Publisher:England: BioMed Central
Journal title:Human genomics, 2024-12, Vol.18 (1), p.134-17, Article 134
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Novel Mutation in the IDS Gene in Hunter Syndrome Associated with Severe Cardiac Lesions
Author / Creator:Satekge, Tumelo M ; Honey, Engela M ; Pitso, Boitumelo ; Dercksen, Marli ; Pillay, Tahir S
Publisher:England: American Association for Clinical Chemistry, Inc
Journal title:Clinical chemistry (Baltimore, Md.), 2021-03, Vol.67 (3), p.564-566
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High-Throughput Liquid Chromatography–Tandem Mass Spectrometry Quantification of Glycosaminoglycans as Biomarkers of Mucopolysaccharidosis II
Author / Creator:Wang, Junhua ; Bhalla, Akhil ; Ullman, Julie C. ; Fang, Meng ; Ravi, Ritesh ; Arguello, Annie ; Thomsen, Elliot ; Tsogtbaatar, Buyankhishig ; Guo, Jing L. ; Skuja, Lukas L. ; Dugas, Jason C. ; Davis, Sonnet S. ; Poda, Suresh B. ; Gunasekaran, Kannan ; Costanzo, Simona ; Sweeney, Zachary K. ; Henry, Anastasia G. ; Harris, Jeffrey M. ; Henne, Kirk R. ; Astarita, Giuseppe
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-07, Vol.21 (15), p.5449
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Case report: a rare case of Hunter syndrome (type II mucopolysaccharidosis) in a girl
Author / Creator:Semyachkina, A. N. ; Voskoboeva, E. Y. ; Zakharova, E. Y. ; Nikolaeva, E. A. ; Kanivets, I. V. ; Kolotii, A. D. ; Baydakova, G. V. ; Kharabadze, M. N. ; Kuramagomedova, R. G. ; Melnikova, N. V.
Publisher:England: BioMed Central Ltd
Journal title:BMC medical genetics, 2019-05, Vol.20 (1), p.66-66, Article 66
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Newsletter articlesFull Text
"Formulations Of Protein Molecules Comprising Iduronate 2-Sulfatase" in Patent Application Approval Process (USPTO 20220184186)
Publisher:NewsRX LLC
Journal title:Biotech Business Week, 2022, p.227
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Patent Issued for Methods and compositions for increasing iduronate 2-sulfatase activity in the CNS
Publisher:NewsRX LLC
Journal title:Journal of Engineering, 2024, p.9510
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Clinical manifestations in female carriers of mucopolysaccharidosis type II: a spanish cross-sectional study
Author / Creator:Guillén-Navarro, Encarna ; Domingo-Jiménez, María ; Alcalde-Martín, Carlos ; Cancho-Candela, Ramón ; Couce, María ; Galán-Gómez, Enrique ; Alonso-Luengo, Olga
Publisher:England: BioMed Central Ltd
Journal title:Orphanet journal of rare diseases, 2013-06, Vol.8 (1), p.92-92
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ArticlesFull Text
Molecular analysis of the novel IDS allele in a Thai family with mucopolysaccharidosis type II: The c.928C>T (p.Gln310) transcript is sensitive to nonsense-mediated mRNA decay
Author / Creator:Ngiwsara, Lukana ; Rojnueangnit, Kitiwan ; Wattanasirichaigoon, Duangrurdee ; Tim-Aroon, Thipwimol ; Sawangareetrakul, Phannee ; Champattanachai, Voraratt ; Ketudat-Cairns, James R. ; Svasti, Jisnuson
Publisher:Greece: Spandidos Publications UK Ltd
Journal title:Experimental and therapeutic medicine, 2017-06, Vol.13 (6), p.2989-2996
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Newsletter articlesFull Text
US Patent Issued to ARMAGEN on July 23 for "Methods and compositions for increasing iduronate 2-sulfatase activity in the CNS" (California Inventors)
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2024
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Newsletter articlesFull Text
INTERNATIONAL PATENT: DENALI THERAPEUTICS INC. FILES APPLICATION FOR "FORMULATIONS OF PROTEIN MOLECULES COMPRISING IDURONATE 2-SULFATASE"
Publisher:Washington, D.C: HT Digital Streams Limited
Journal title:US Fed News Service, Including US State News, 2020
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Newsletter articlesFull Text
Armagen Assigned Patent for Increasing Iduronate 2-Sulfatase Activity in CNS
Publisher:Washington, D.C: Targeted News Service
Journal title:Targeted News Service, 2018
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Newsletter articlesFull Text
U.S. Patent and Trademark Office Awards Patent for Methods and Compositions for Increasing Iduronate 2-Sulfatase Activity in the CNS
Publisher:New Delhi: Pedia Content Solutions Pvt. Ltd
Journal title:Global IP News. Pharmaceutical Patent News, 2021
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Oral trehalose improves histological and behavior symptoms of mucopolysaccharidosis type II in iduronate 2-sulfatase deficient mice

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In vivo brain delivery of BBB-enabled iduronate 2-sulfatase in rats

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Characterization of a HIR-Fab-IDS, Novel Iduronate 2-Sulfatase Fusion Protein for the Treatment of Neuropathic Mucopolysaccharidosis Type II (Hunter Syndrome)

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Shutdown of ER-associated degradation pathway rescues functions of mutant iduronate 2-sulfatase linked to mucopolysaccharidosis type II

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Novel variations in Exon 4 of the iduronate 2-sulfatase gene in six Indonesian patients with mucopolysaccharidosis type II

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Comparative studies of vertebrate iduronate 2-sulfatase (IDS) genes and proteins: evolution of A mammalian X-linked gene

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724. Alternative Splicing of the Human Iduronate 2-Sulfatase Gene and Implications in Gene Therapy

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Glycosaminoglycan signatures in body fluids of mucopolysaccharidosis type II mouse model under long-term enzyme replacement therapy

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Molecular basis of mucopolysaccharidosis type II (Hunter syndrome): first review and classification of published IDS gene variants

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Novel Mutation in the IDS Gene in Hunter Syndrome Associated with Severe Cardiac Lesions

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High-Throughput Liquid Chromatography–Tandem Mass Spectrometry Quantification of Glycosaminoglycans as Biomarkers of Mucopolysaccharidosis II

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Case report: a rare case of Hunter syndrome (type II mucopolysaccharidosis) in a girl

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"Formulations Of Protein Molecules Comprising Iduronate 2-Sulfatase" in Patent Application Approval Process (USPTO 20220184186)

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Patent Issued for Methods and compositions for increasing iduronate 2-sulfatase activity in the CNS

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Clinical manifestations in female carriers of mucopolysaccharidosis type II: a spanish cross-sectional study

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Molecular analysis of the novel IDS allele in a Thai family with mucopolysaccharidosis type II: The c.928C>T (p.Gln310) transcript is sensitive to nonsense-mediated mRNA decay

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US Patent Issued to ARMAGEN on July 23 for "Methods and compositions for increasing iduronate 2-sulfatase activity in the CNS" (California Inventors)

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INTERNATIONAL PATENT: DENALI THERAPEUTICS INC. FILES APPLICATION FOR "FORMULATIONS OF PROTEIN MOLECULES COMPRISING IDURONATE 2-SULFATASE"

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Armagen Assigned Patent for Increasing Iduronate 2-Sulfatase Activity in CNS

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U.S. Patent and Trademark Office Awards Patent for Methods and Compositions for Increasing Iduronate 2-Sulfatase Activity in the CNS

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