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ArticlesPeer ReviewedFull Text
Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A
Author / Creator:Ogawa, Yasushi ; Nonaka, Yosuke ; Goto, Toshiyasu ; Ohnishi, Eriko ; Hiramatsu, Toshiyuki ; Kii, Isao ; Yoshida, Miyo ; Ikura, Teikichi ; Onogi, Hiroshi ; Shibuya, Hiroshi ; Hosoya, Takamitsu ; Ito, Nobutoshi ; Hagiwara, Masatoshi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2010-10, Vol.1 (1), p.86, Article 86
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ArticlesPeer ReviewedFull Text
Selective inhibition of the kinase DYRK1A by targeting its folding process
Author / Creator:Kii, Isao ; Sumida, Yuto ; Goto, Toshiyasu ; Sonamoto, Rie ; Okuno, Yukiko ; Yoshida, Suguru ; Kato-Sumida, Tomoe ; Koike, Yuka ; Abe, Minako ; Nonaka, Yosuke ; Ikura, Teikichi ; Ito, Nobutoshi ; Shibuya, Hiroshi ; Hosoya, Takamitsu ; Hagiwara, Masatoshi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-04, Vol.7 (1), p.11391-14, Article 11391
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ArticlesPeer ReviewedFull Text
Structural Analysis of Hen Egg Lysozyme Refolded after Denaturation at Acidic pH
Author / Creator:Oda, Masayuki ; Sano, Tomoki ; Kamatari, Yuji O. ; Abe, Yoshito ; Ikura, Teikichi ; Ito, Nobutoshi
Publisher:New York: Springer US
Journal title:The Protein Journal, 2022-02, Vol.41 (1), p.71-78
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ArticlesPeer ReviewedFull Text
Energetics and kinetics of substrate analog-coupled staphylococcal nuclease folding revealed by a statistical mechanical approach
Author / Creator:Mizukami, Takuya ; Furuzawa, Shunta ; Itoh, Satoru G. ; Segawa, Saho ; Ikura, Teikichi ; Ihara, Kunio ; Okumura, Hisashi ; Roder, Heinrich ; Maki, Kosuke
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-08, Vol.117 (33), p.19953-19962
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ArticlesPeer ReviewedFull Text
HMGB1 signaling phosphorylates Ku70 and impairs DNA damage repair in Alzheimer’s disease pathology
Author / Creator:Tanaka, Hikari ; Kondo, Kanoh ; Fujita, Kyota ; Homma, Hidenori ; Tagawa, Kazuhiko ; Jin, Xiaocen ; Jin, Meihua ; Yoshioka, Yuki ; Takayama, Sumire ; Masuda, Hitomi ; Tokuyama, Rie ; Nakazaki, Yukoh ; Saito, Takashi ; Saido, Takaomi ; Murayama, Shigeo ; Ikura, Teikichi ; Ito, Nobutoshi ; Yamamori, Yu ; Tomii, Kentaro ; Bianchi, Marco E. ; Okazawa, Hitoshi
Publisher:London: Nature Publishing Group UK
Journal title:Communications biology, 2021-10, Vol.4 (1), p.1175-1175, Article 1175
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ArticlesPeer ReviewedFull Text
High resolution crystal structure of the Grb2 SH2 domain with a phosphopeptide derived from CD28
Author / Creator:Higo, Kunitake ; Ikura, Teikichi ; Oda, Masayuki ; Morii, Hisayuki ; Takahashi, Jun ; Abe, Ryo ; Ito, Nobutoshi
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-09, Vol.8 (9), p.e74482-e74482
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ArticlesPeer ReviewedFull Text
Identification of hepta-histidine as a candidate drug for Huntington’s disease by in silico-in vitro- in vivo-integrated screens of chemical libraries
Author / Creator:Imamura, Tomomi ; Fujita, Kyota ; Tagawa, Kazuhiko ; Ikura, Teikichi ; Chen, Xigui ; Homma, Hidenori ; Tamura, Takuya ; Mao, Ying ; Taniguchi, Juliana Bosso ; Motoki, Kazumi ; Nakabayashi, Makoto ; Ito, Nobutoshi ; Yamada, Kazunori ; Tomii, Kentaro ; Okano, Hideyuki ; Kaye, Julia ; Finkbeiner, Steven ; Okazawa, Hitoshi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-09, Vol.6 (1), p.33861-33861, Article 33861
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ArticlesPeer ReviewedFull Text
Halophilic mechanism of the enzymatic function of a moderately halophilic dihydrofolate reductase from Haloarcula japonica strain TR-1
Author / Creator:Miyashita, Yurina ; Ohmae, Eiji ; Ikura, Teikichi ; Nakasone, Kaoru ; Katayanagi, Katsuo
Publisher:Tokyo: Springer Japan
Journal title:Extremophiles : life under extreme conditions, 2017-05, Vol.21 (3), p.591-602
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ArticlesPeer ReviewedFull Text
Critical roles of Asp270 and Trp273 in the α-repeat of the carbohydrate-binding module of endo-1,3-β-glucanase for laminarin-binding avidity
Author / Creator:Tamashiro, Tomonari ; Tanabe, Yoichi ; Ikura, Teikichi ; Ito, Nobutoshi ; Oda, Masayuki
Publisher:Boston: Springer US
Journal title:Glycoconjugate journal, 2012-01, Vol.29 (1), p.77-85
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ArticlesPeer ReviewedFull Text
Critical roles of Asp270 and Trp273 in the [alpha]-repeat of the carbohydrate-binding module of endo-1,3-[beta]-glucanase for laminarin-binding avidity
Author / Creator:Tamashiro, Tomonari ; Tanabe, Yoichi ; Ikura, Teikichi ; Ito, Nobutoshi ; Oda, Masayuki
Publisher:New York: Springer Nature B.V
Journal title:Glycoconjugate journal, 2012-01, Vol.29 (1), p.77
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Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A

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Selective inhibition of the kinase DYRK1A by targeting its folding process

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Structural Analysis of Hen Egg Lysozyme Refolded after Denaturation at Acidic pH

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Energetics and kinetics of substrate analog-coupled staphylococcal nuclease folding revealed by a statistical mechanical approach

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HMGB1 signaling phosphorylates Ku70 and impairs DNA damage repair in Alzheimer’s disease pathology

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High resolution crystal structure of the Grb2 SH2 domain with a phosphopeptide derived from CD28

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Identification of hepta-histidine as a candidate drug for Huntington’s disease by in silico-in vitro- in vivo-integrated screens of chemical libraries

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Halophilic mechanism of the enzymatic function of a moderately halophilic dihydrofolate reductase from Haloarcula japonica strain TR-1

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Critical roles of Asp270 and Trp273 in the α-repeat of the carbohydrate-binding module of endo-1,3-β-glucanase for laminarin-binding avidity

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Critical roles of Asp270 and Trp273 in the [alpha]-repeat of the carbohydrate-binding module of endo-1,3-[beta]-glucanase for laminarin-binding avidity

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