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Reference EntriesFull Text
Iyer, Shankar S
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: ING-KNI, 2022, p.5395-5395
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Iyer, Shankar S
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: ING-KNI, 2021, p.5375-5375
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ArticlesPeer ReviewedFull Text
How colonization by microbiota in early life shapes the immune system
Author / Creator:Gensollen, Thomas ; Iyer, Shanker S. ; Kasper, Dennis L. ; Blumberg, Richard S.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2016-04, Vol.352 (6285), p.539-544
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ArticlesPeer ReviewedFull Text
The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response
Author / Creator:Parvatiyar, Kislay ; Zhang, Zhiqiang ; Teles, Rosane M ; Ouyang, Songying ; Jiang, Yan ; Iyer, Shankar S ; Zaver, Shivam A ; Schenk, Mirjam ; Zeng, Shang ; Zhong, Wenwan ; Liu, Zhi-Jie ; Modlin, Robert L ; Liu, Yong-jun ; Cheng, Genhong
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2012-12, Vol.13 (12), p.1155-1161
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ArticlesPeer ReviewedFull Text
Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation
Author / Creator:Covarrubias, Anthony J ; Aksoylar, Halil Ibrahim ; Yu, Jiujiu ; Snyder, Nathaniel W ; Worth, Andrew J ; Iyer, Shankar S ; Wang, Jiawei ; Ben-Sahra, Issam ; Byles, Vanessa ; Polynne-Stapornkul, Tiffany ; Espinosa, Erika C ; Lamming, Dudley ; Manning, Brendan D ; Zhang, Yijing ; Blair, Ian A ; Horng, Tiffany
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2016-02, Vol.5
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ArticlesPeer ReviewedFull Text
Mast Cells in Stress, Pain, Blood-Brain Barrier, Neuroinflammation and Alzheimer's Disease
Author / Creator:Kempuraj, Duraisamy ; Mentor, Shireen ; Thangavel, Ramasamy ; Ahmed, Mohammad E ; Selvakumar, Govindhasamy Pushpavathi ; Raikwar, Sudhanshu P ; Dubova, Iuliia ; Zaheer, Smita ; Iyer, Shankar S ; Zaheer, Asgar
Publisher:Switzerland: Frontiers Research Foundation
Journal title:Frontiers in cellular neuroscience, 2019-02, Vol.13, p.54
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ArticlesPeer ReviewedFull Text
Type I Interferon Suppresses Type II Interferon—Triggered Human Anti-Mycobacterial Responses
Author / Creator:Teles, Rosane M. B. ; Graeber, Thomas G. ; Krutzik, Stephan R. ; Montoya, Dennis ; Schenk, Mirjam ; Lee, Delphine J. ; Komisopoulou, Evangelia ; Kelly-Scumpia, Kindra ; Chun, Rene ; Iyer, Shankar S. ; Sarno, Euzenir N. ; Rea, Thomas H. ; Hewison, Martin ; Adams, John S. ; Popper, Stephen J. ; Relman, David A. ; Stenger, Steffen ; Bloom, Barry R. ; Cheng, Genhong ; Modlin, Robert L.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2013-03, Vol.339 (6126), p.1448-1453
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ArticlesPeer ReviewedFull Text
Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome
Author / Creator:Iyer, Shankar S ; Pulskens, Wilco P ; Sadler, Jeffrey J ; Butter, Loes M ; Teske, Gwendoline J ; Ulland, Tyler K ; Eisenbarth, Stephanie C ; Florquin, Sandrine ; Flavell, Richard A ; Leemans, Jaklien C ; Sutterwala, Fayyaz S
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2009-12, Vol.106 (48), p.20388-20393
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ArticlesPeer ReviewedFull Text
Nalp3 inflammasome is essential for the development of silicosis
Author / Creator:Cassel, Suzanne L ; Eisenbarth, Stephanie C ; Iyer, Shankar S ; Sadler, Jeffrey J ; Colegio, Oscar R ; Tephly, Linda A ; Carter, A. Brent ; Rothman, Paul B ; Flavell, Richard A ; Sutterwala, Fayyaz S
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2008-07, Vol.105 (26), p.9035-9040
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ArticlesPeer ReviewedFull Text
Mast Cell Activation in Brain Injury, Stress, and Post-traumatic Stress Disorder and Alzheimer's Disease Pathogenesis
Author / Creator:Kempuraj, Duraisamy ; Selvakumar, Govindhasamy P ; Thangavel, Ramasamy ; Ahmed, Mohammad E ; Zaheer, Smita ; Raikwar, Sudhanshu P ; Iyer, Shankar S ; Bhagavan, Sachin M ; Beladakere-Ramaswamy, Swathi ; Zaheer, Asgar
Publisher:Switzerland: Frontiers Research Foundation
Journal title:Frontiers in neuroscience, 2017-12, Vol.11, p.703-703
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ArticlesPeer ReviewedFull Text
Mast Cell Activation, Neuroinflammation, and Tight Junction Protein Derangement in Acute Traumatic Brain Injury
Author / Creator:Zaheer, Asgar ; James, Donald ; Iyer, Shankar S. ; Zaheer, Smita A. ; Raikwar, Sudhanshu P. ; Thangavel, Ramasamy ; Selvakumar, Govindhasamy Pushpavathi ; Ahmed, Mohammad Ejaz ; Kempuraj, Duraisamy ; Burton, Casey
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:Mediators of inflammation, 2020, Vol.2020 (2020), p.1-12
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ArticlesPeer ReviewedFull Text
Psychological Stress–Induced Immune Response and Risk of Alzheimer's Disease in Veterans from Operation Enduring Freedom and Operation Iraqi Freedom
Author / Creator:Kempuraj, Duraisamy, PhD ; Ahmed, Mohammad Ejaz, PhD ; Selvakumar, Govindhasamy Pushpavathi, PhD ; Thangavel, Ramasamy, PhD ; Raikwar, Sudhanshu P., PhD ; Zaheer, Smita A., PhD ; Iyer, Shankar S., PhD ; Burton, Casey, PhD ; James, Donald, DO ; Zaheer, Asgar, PhD
Publisher:United States: Elsevier Inc
Journal title:Clinical therapeutics, 2020-06, Vol.42 (6), p.974-982
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ArticlesPeer ReviewedFull Text
Glia Maturation Factor and Mitochondrial Uncoupling Proteins 2 and 4 Expression in the Temporal Cortex of Alzheimer's Disease Brain
Author / Creator:Thangavel, Ramasamy ; Kempuraj, Duraisamy ; Zaheer, Smita ; Raikwar, Sudhanshu ; Ahmed, Mohammad E ; Selvakumar, Govindhasamy Pushpavathi ; Iyer, Shankar S ; Zaheer, Asgar
Publisher:Switzerland: Frontiers Research Foundation
Journal title:Frontiers in aging neuroscience, 2017-05, Vol.9, p.150
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ArticlesPeer ReviewedFull Text
Three novel downstream promoter elements regulate MHC class I promoter activity in mammalian cells
Author / Creator:Lee, Namhoon ; Iyer, Shankar S ; Mu, Jie ; Weissman, Jocelyn D ; Ohali, Anat ; Howcroft, T Kevin ; Lewis, Brian A ; Singer, Dinah S
Publisher:United States: Public Library of Science
Journal title:PloS one, 2010-12, Vol.5 (12), p.e15278
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ArticlesPeer ReviewedFull Text
Mast Cell Proteases Activate Astrocytes and Glia-Neurons and Release Interleukin-33 by Activating p38 and ERK1/2 MAPKs and NF-κB
Author / Creator:Kempuraj, Duraisamy ; Thangavel, Ramasamy ; Selvakumar, Gvindhasamy Pushpavathi ; Ahmed, Mohammad Ejaz ; Zaheer, Smita ; Raikwar, Sudhanshu P. ; Zahoor, Haris ; Saeed, Daniyal ; Dubova, Iuliia ; Giler, Gema ; Herr, Shelby ; Iyer, Shankar S. ; Zaheer, Asgar
Publisher:New York: Springer US
Journal title:Molecular neurobiology, 2019-03, Vol.56 (3), p.1681-1693
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Targeted Gene Editing of Glia Maturation Factor in Microglia: a Novel Alzheimer’s Disease Therapeutic Target
Author / Creator:Raikwar, Sudhanshu P. ; Thangavel, Ramasamy ; Dubova, Iuliia ; Selvakumar, Govindhasamy Pushpavathi ; Ahmed, Mohammad Ejaz ; Kempuraj, Duraisamy ; Zaheer, Smita A. ; Iyer, Shankar S. ; Zaheer, Asgar
Publisher:New York: Springer US
Journal title:Molecular neurobiology, 2019-01, Vol.56 (1), p.378-393
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Newsletter articlesFull Text
Iyer Shankar S, Llebaria Amadeu and The Brigham and Womens Hospital Get Patent for Oxazole Containing Compounds as Activators of IDO1 and AHR
Publisher:New Delhi: Pedia Content Solutions Pvt. Ltd
Journal title:Global IP News. Medical Patent News, 2023
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Sterile activation of invariant natural killer T cells by ER-stressed antigen-presenting cells
Author / Creator:Bedard, Melissa ; Shrestha, Dilip ; Priestman, David A. ; Wang, Yuting ; Schneider, Falk ; Matute, Juan D. ; Iyer, Shankar S. ; Gileadi, Uzi ; Prota, Gennaro ; Kandasamy, Matheswaran ; Veerapen, Natacha ; Besra, Gurdyal ; Fritzsche, Marco ; Zeissig, Sebastian ; Shevchenko, Andrej ; Christianson, John C. ; Platt, Frances M. ; Eggeling, Christian ; Blumberg, Richard S. ; Salio, Mariolina ; Cerundolo, Vincenzo
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-11, Vol.116 (47), p.23671-23681
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Glia Maturation Factor Dependent Inhibition of Mitochondrial PGC-1α Triggers Oxidative Stress-Mediated Apoptosis in N27 Rat Dopaminergic Neuronal Cells
Author / Creator:Selvakumar, Govindhasamy Pushpavathi ; Iyer, Shankar S ; Kempuraj, Duraisamy ; Raju, Murugesan ; Thangavel, Ramasamy ; Saeed, Daniyal ; Ahmed, Mohammad Ejaz ; Zahoor, Harris ; Raikwar, Sudhanshu P. ; Zaheer, Smita ; Zaheer, Asgar
Publisher:New York: Springer US
Journal title:Molecular neurobiology, 2018-09, Vol.55 (9), p.7132-7152
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ArticlesPeer ReviewedFull Text
SLAM-ing the brakes on iNKT cell selection
Author / Creator:Iyer, Shankar S. ; Huang, Yu-Hwa ; Blumberg, Richard S.
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2019-04, Vol.20 (4), p.378-379
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Iyer, Shankar S

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Iyer, Shankar S

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How colonization by microbiota in early life shapes the immune system

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The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response

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Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation

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Mast Cells in Stress, Pain, Blood-Brain Barrier, Neuroinflammation and Alzheimer's Disease

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Type I Interferon Suppresses Type II Interferon—Triggered Human Anti-Mycobacterial Responses

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Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

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Nalp3 inflammasome is essential for the development of silicosis

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Mast Cell Activation in Brain Injury, Stress, and Post-traumatic Stress Disorder and Alzheimer's Disease Pathogenesis

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Mast Cell Activation, Neuroinflammation, and Tight Junction Protein Derangement in Acute Traumatic Brain Injury

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Psychological Stress–Induced Immune Response and Risk of Alzheimer's Disease in Veterans from Operation Enduring Freedom and Operation Iraqi Freedom

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Glia Maturation Factor and Mitochondrial Uncoupling Proteins 2 and 4 Expression in the Temporal Cortex of Alzheimer's Disease Brain

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Three novel downstream promoter elements regulate MHC class I promoter activity in mammalian cells

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Mast Cell Proteases Activate Astrocytes and Glia-Neurons and Release Interleukin-33 by Activating p38 and ERK1/2 MAPKs and NF-κB

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Targeted Gene Editing of Glia Maturation Factor in Microglia: a Novel Alzheimer’s Disease Therapeutic Target

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Iyer Shankar S, Llebaria Amadeu and The Brigham and Womens Hospital Get Patent for Oxazole Containing Compounds as Activators of IDO1 and AHR

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Sterile activation of invariant natural killer T cells by ER-stressed antigen-presenting cells

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Glia Maturation Factor Dependent Inhibition of Mitochondrial PGC-1α Triggers Oxidative Stress-Mediated Apoptosis in N27 Rat Dopaminergic Neuronal Cells

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SLAM-ing the brakes on iNKT cell selection

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