Type I Interferon Suppresses Type II Interferon—Triggered Human Anti-Mycobacterial Responses
Type I Interferon Suppresses Type II Interferon—Triggered Human Anti-Mycobacterial Responses
About this item
Full title
Author / Creator
Teles, Rosane M. B. , Graeber, Thomas G. , Krutzik, Stephan R. , Montoya, Dennis , Schenk, Mirjam , Lee, Delphine J. , Komisopoulou, Evangelia , Kelly-Scumpia, Kindra , Chun, Rene , Iyer, Shankar S. , Sarno, Euzenir N. , Rea, Thomas H. , Hewison, Martin , Adams, John S. , Popper, Stephen J. , Relman, David A. , Stenger, Steffen , Bloom, Barry R. , Cheng, Genhong and Modlin, Robert L.
Publisher
United States: American Association for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Type I interferons (IFN-α and IFN-β) are important for protection against many viral infections, whereas type II interferon (IFN-γ) is essential for host defense against some bacterial and parasitic pathogens. Study of IFN responses in human leprosy revealed an inverse correlation between IFN-β and IFN-γ gene expression programs. IFN-γ and its down...
Alternative Titles
Full title
Type I Interferon Suppresses Type II Interferon—Triggered Human Anti-Mycobacterial Responses
Authors, Artists and Contributors
Author / Creator
Graeber, Thomas G.
Krutzik, Stephan R.
Montoya, Dennis
Schenk, Mirjam
Lee, Delphine J.
Komisopoulou, Evangelia
Kelly-Scumpia, Kindra
Chun, Rene
Iyer, Shankar S.
Sarno, Euzenir N.
Rea, Thomas H.
Hewison, Martin
Adams, John S.
Popper, Stephen J.
Relman, David A.
Stenger, Steffen
Bloom, Barry R.
Cheng, Genhong
Modlin, Robert L.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3653587
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3653587
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1233665
