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ArticlesPeer ReviewedFull Text
Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning
Author / Creator:Sellgren, Carl M. ; Gracias, Jessica ; Watmuff, Bradley ; Biag, Jonathan D. ; Thanos, Jessica M. ; Whittredge, Paul B. ; Fu, Ting ; Worringer, Kathleen ; Brown, Hannah E. ; Wang, Jennifer ; Kaykas, Ajamete ; Karmacharya, Rakesh ; Goold, Carleton P. ; Sheridan, Steven D. ; Perlis, Roy H.
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2019-03, Vol.22 (3), p.374-385
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ArticlesPeer ReviewedFull Text
Advances toward precision medicine for bipolar disorder: mechanisms & molecules
Author / Creator:Haggarty, Stephen J. ; Karmacharya, Rakesh ; Perlis, Roy H.
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2021-01, Vol.26 (1), p.168-185
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ArticlesPeer ReviewedFull Text
HDAC6 Modulates Signaling Pathways Relevant to Synaptic Biology and Neuronal Differentiation in Human Stem-Cell-Derived Neurons
Author / Creator:Iaconelli, Jonathan ; Xuan, Lucius ; Karmacharya, Rakesh
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2019-03, Vol.20 (7), p.1605
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ArticlesPeer ReviewedFull Text
Transcriptome analysis and functional characterization of cerebral organoids in bipolar disorder
Author / Creator:Kathuria, Annie ; Lopez-Lengowski, Kara ; Vater, Magdalena ; McPhie, Donna ; Cohen, Bruce M ; Karmacharya, Rakesh
Publisher:England: BioMed Central Ltd
Journal title:Genome medicine, 2020-04, Vol.12 (1), p.34-34, Article 34
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ArticlesPeer ReviewedFull Text
Integrating stem cell-based experiments in clinical research
Author / Creator:Karmacharya, Rakesh ; Kieling, Christian ; Mondelli, Valeria
Publisher:England: Cambridge University Press
Journal title:European psychiatry, 2020-06, Vol.63 (1), p.e62-e62, Article e62
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ArticlesPeer ReviewedFull Text
Morphological and transcriptomic analyses of stem cell-derived cortical neurons reveal mechanisms underlying synaptic dysfunction in schizophrenia
Author / Creator:Kathuria, Annie ; Lopez-Lengowski, Kara ; Watmuff, Bradley ; Karmacharya, Rakesh
Publisher:England: BioMed Central Ltd
Journal title:Genome medicine, 2023-07, Vol.15 (1), p.58-58, Article 58
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Synaptic deficits in iPSC-derived cortical interneurons in schizophrenia are mediated by NLGN2 and rescued by N-acetylcysteine
Author / Creator:Kathuria, Annie ; Lopez-Lengowski, Kara ; Watmuff, Bradley ; McPhie, Donna ; Cohen, Bruce M. ; Karmacharya, Rakesh
Publisher:London: Nature Publishing Group UK
Journal title:Translational psychiatry, 2019-11, Vol.9 (1), p.321-13, Article 321
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Disease-specific differences in gene expression, mitochondrial function and mitochondria-endoplasmic reticulum interactions in iPSC-derived cerebral organoids and cortical neurons in schizophrenia and...
Author / Creator:Kathuria, Annie ; Lopez-Lengowski, Kara ; McPhie, Donna ; Cohen, Bruce M. ; Karmacharya, Rakesh
Publisher:Cham: Springer International Publishing
Journal title:Discover Mental Health, 2023-03, Vol.3 (1), p.8-8, Article 8
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Protocol for a systematic review of the development of depression among adolescents and young adults: psychological, biological, and contextual perspectives around the world
Author / Creator:Pedersen, Gloria A ; Zajkowska, Zuzanna ; Kieling, Christian ; Gautam, Kamal ; Mondelli, Valeria ; Fisher, Helen L ; Swartz, Johnna R ; Adewuya, Abiodun ; Karmacharya, Rakesh ; Kohrt, Brandon A
Publisher:England: BioMed Central
Journal title:Systematic reviews, 2019-07, Vol.8 (1), p.179-179, Article 179
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ArticlesPeer ReviewedFull Text
Brain microvascular endothelial cells and blood-brain barrier dysfunction in psychotic disorders
Author / Creator:Lizano, Paulo ; Pong, Sovannarath ; Santarriaga, Stephanie ; Bannai, Deepthi ; Karmacharya, Rakesh
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2023-09, Vol.28 (9), p.3698-3708
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ArticlesPeer ReviewedFull Text
Stem cell-derived neurons in the development of targeted treatment for schizophrenia and bipolar disorder
Author / Creator:Watmuff, Bradley ; Liu, Bangyan ; Karmacharya, Rakesh
Publisher:England: Future Medicine Ltd
Journal title:Pharmacogenomics, 2017-04, Vol.18 (5), p.471-479
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ArticlesPeer ReviewedFull Text
Clozapine Interaction with Phosphatidyl Inositol 3-Kinase (PI3K)/Insulin-Signaling Pathway in Caenorhabditis elegans
Author / Creator:Karmacharya, Rakesh ; Sliwoski, Gregory R ; Lundy, Miriam Y ; Suckow, Raymond F ; Cohen, Bruce M ; Buttner, Edgar A
Publisher:Cham: Springer International Publishing
Journal title:Neuropsychopharmacology (New York, N.Y.), 2009-07, Vol.34 (8), p.1968-1978
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ArticlesPeer ReviewedFull Text
Clozapine Interaction with Phosphatidyl Inositol 3-Kinase (PI3K)/Insulin-Signaling Pathwray in Caenorhabditis elegans
Author / Creator:KARMACHARYA, Rakesh ; SLIWOSKI, Gregory R ; LUNDY, Miriam Y ; SUCKOW, Raymond F ; COHEN, Bruce M ; BUTTNER, Edgar A
Publisher:Basingstoke: Nature Publishing Group
Journal title:Neuropsychopharmacology (New York, N.Y.), 2009, Vol.34 (8), p.1968-1978
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ReportsFull Text
Advances toward precision medicine for bipolar disorder: mechanisms molecules
Author / Creator:Haggarty, Stephen J ; Karmacharya, Rakesh ; Perlis, Roy H
Publisher:Nature Publishing Group
Journal title:Molecular Psychiatry, 2021, Vol.26 (1), p.168
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ArticlesFull Text
Increased microglial synapse elimination in patient-specific models of schizophrenia
Author / Creator:Sellgren, Carl M ; Gracias, Jessica ; Watmuff, Bradley ; Goold, Carleton P ; Thanos, Jessica M ; Fu, Ting ; Karmacharya, Rakesh ; Brown, Hannah E ; Wang, Jennifer ; Sheridan, Steven D ; Perlis, Roy H
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2017-12
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Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning

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Advances toward precision medicine for bipolar disorder: mechanisms & molecules

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HDAC6 Modulates Signaling Pathways Relevant to Synaptic Biology and Neuronal Differentiation in Human Stem-Cell-Derived Neurons

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Transcriptome analysis and functional characterization of cerebral organoids in bipolar disorder

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Integrating stem cell-based experiments in clinical research

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Morphological and transcriptomic analyses of stem cell-derived cortical neurons reveal mechanisms underlying synaptic dysfunction in schizophrenia

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Synaptic deficits in iPSC-derived cortical interneurons in schizophrenia are mediated by NLGN2 and rescued by N-acetylcysteine

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Disease-specific differences in gene expression, mitochondrial function and mitochondria-endoplasmic reticulum interactions in iPSC-derived cerebral organoids and cortical neurons in schizophrenia and...

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Protocol for a systematic review of the development of depression among adolescents and young adults: psychological, biological, and contextual perspectives around the world

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Brain microvascular endothelial cells and blood-brain barrier dysfunction in psychotic disorders

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Stem cell-derived neurons in the development of targeted treatment for schizophrenia and bipolar disorder

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Clozapine Interaction with Phosphatidyl Inositol 3-Kinase (PI3K)/Insulin-Signaling Pathway in Caenorhabditis elegans

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Clozapine Interaction with Phosphatidyl Inositol 3-Kinase (PI3K)/Insulin-Signaling Pathwray in Caenorhabditis elegans

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Advances toward precision medicine for bipolar disorder: mechanisms molecules

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Increased microglial synapse elimination in patient-specific models of schizophrenia

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