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Peptides from the Sea Anemone Metridium senile with Modified Inhibitor Cystine Knot (ICK) Fold Inhibit Nicotinic Acetylcholine Receptors
Author / Creator:Kasheverov, Igor E ; Logashina, Yulia A ; Kornilov, Fedor D ; Lushpa, Vladislav A ; Maleeva, Ekaterina E ; Korolkova, Yuliya V ; Yu, Jinpeng ; Zhu, Xiaopeng ; Zhangsun, Dongting ; Luo, Sulan ; Stensvåg, Klara ; Kudryavtsev, Denis S ; Mineev, Konstantin S ; Andreev, Yaroslav A
Publisher:Switzerland: MDPI AG
Journal title:Toxins, 2022-12, Vol.15 (1), p.28
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Pancreatic and snake venom presynaptically active phospholipases A2 inhibit nicotinic acetylcholine receptors
Author / Creator:Vulfius, Catherine A ; Kasheverov, Igor E ; Kryukova, Elena V ; Spirova, Ekaterina N ; Shelukhina, Irina V ; Starkov, Vladislav G ; Andreeva, Tatyana V ; Faure, Grazyna ; Zouridakis, Marios ; Tsetlin, Victor I ; Utkin, Yuri N
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-10, Vol.12 (10), p.e0186206
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Analogs of 6-Bromohypaphorine with Increased Agonist Potency for α7 Nicotinic Receptor as Anti-Inflammatory Analgesic Agents
Author / Creator:Ivanov, Igor A ; Siniavin, Andrei E ; Palikov, Victor A ; Senko, Dmitry A ; Shelukhina, Irina V ; Epifanova, Lyubov A ; Ojomoko, Lucy O ; Belukhina, Svetlana Y ; Prokopev, Nikita A ; Landau, Mariia A ; Palikova, Yulia A ; Kazakov, Vitaly A ; Borozdina, Natalia A ; Bervinova, Arina V ; Dyachenko, Igor A ; Kasheverov, Igor E ; Tsetlin, Victor I ; Kudryavtsev, Denis S
Publisher:Switzerland: MDPI AG
Journal title:Marine drugs, 2023-06, Vol.21 (6), p.368
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Nicotinic Acetylcholine Receptors Are Novel Targets of APETx-like Toxins from the Sea Anemone Heteractis magnifica
Author / Creator:Kalina, Rimma S ; Kasheverov, Igor E ; Koshelev, Sergey G ; Sintsova, Oksana V ; Peigneur, Steve ; Pinheiro-Junior, Ernesto Lopes ; Popov, Roman S ; Chausova, Victoria E ; Monastyrnaya, Margarita M ; Dmitrenok, Pavel S ; Isaeva, Marina P ; Tytgat, Jan ; Kozlov, Sergey A ; Kozlovskaya, Emma P ; Leychenko, Elena V ; Gladkikh, Irina N
Publisher:Switzerland: MDPI AG
Journal title:Toxins, 2022-10, Vol.14 (10), p.697
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Inhibition of nicotinic acetylcholine receptors, a novel facet in the pleiotropic activities of snake venom phospholipases A2
Author / Creator:Vulfius, Catherine A ; Kasheverov, Igor E ; Starkov, Vladislav G ; Osipov, Alexey V ; Andreeva, Tatyana V ; Filkin, Sergey Yu ; Gorbacheva, Elena V ; Astashev, Maxim E ; Tsetlin, Victor I ; Utkin, Yuri N
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-12, Vol.9 (12), p.e115428-e115428
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Curare alkaloids from Matis Dart Poison: Comparison with d-tubocurarine in interactions with nicotinic, 5-HT3 serotonin and GABAA receptors
Author / Creator:Spirova, Ekaterina N ; Ivanov, Igor A ; Kasheverov, Igor E ; Kudryavtsev, Denis S ; Shelukhina, Irina V ; Garifulina, Alexandra I ; Son, Lina V ; Lummis, Sarah C R ; Malca-Garcia, Gonzalo R ; Bussmann, Rainer W ; Hennig, Lothar ; Giannis, Athanassios ; Tsetlin, Victor I
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019, Vol.14 (1), p.e0210182
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Arachidonoylcholine and Other Unsaturated Long-Chain Acylcholines Are Endogenous Modulators of the Acetylcholine Signaling System
Author / Creator:Akimov, Mikhail G ; Kudryavtsev, Denis S ; Kryukova, Elena V ; Fomina-Ageeva, Elena V ; Zakharov, Stanislav S ; Gretskaya, Natalia M ; Zinchenko, Galina N ; Serkov, Igor V ; Makhaeva, Galina F ; Boltneva, Natalia P ; Kovaleva, Nadezhda V ; Serebryakova, Olga G ; Lushchekina, Sofya V ; Palikov, Victor A ; Palikova, Yulia ; Dyachenko, Igor A ; Kasheverov, Igor E ; Tsetlin, Victor I ; Bezuglov, Vladimir V
Publisher:Switzerland: MDPI
Journal title:Biomolecules (Basel, Switzerland), 2020-02, Vol.10 (2), p.283
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ArticlesPeer ReviewedFull Text
Makaluvamine G from the Marine Sponge Zyzzia fuliginosa Inhibits Muscle nAChR by Binding at the Orthosteric and Allosteric Sites
Author / Creator:Kudryavtsev, Denis S ; Spirova, Ekaterina N ; Shelukhina, Irina V ; Son, Lina V ; Makarova, Yana V ; Utkina, Natalia K ; Kasheverov, Igor E ; Tsetlin, Victor I
Publisher:Switzerland: MDPI AG
Journal title:Marine drugs, 2018-03, Vol.16 (4), p.109
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ArticlesPeer ReviewedFull Text
Orthosteric and/or Allosteric Binding of α-Conotoxins to Nicotinic Acetylcholine Receptors and Their Models
Author / Creator:Kryukova, Elena V ; Ivanov, Igor A ; Lebedev, Dmitry S ; Spirova, Ekaterina N ; Egorova, Natalia S ; Zouridakis, Marios ; Kasheverov, Igor E ; Tzartos, Socrates J ; Tsetlin, Victor I
Publisher:Switzerland: MDPI AG
Journal title:Marine drugs, 2018-11, Vol.16 (12), p.460
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ArticlesPeer ReviewedFull Text
Isomerization of Asp7 in Beta-Amyloid Enhances Inhibition of the α7 Nicotinic Receptor and Promotes Neurotoxicity
Author / Creator:Barykin, Evgeny P ; Garifulina, Alexandra I ; Kruykova, Elena V ; Spirova, Ekaterina N ; Anashkina, Anastasia A ; Adzhubei, Alexei A ; Shelukhina, Irina V ; Kasheverov, Igor E ; Mitkevich, Vladimir A ; Kozin, Sergey A ; Hollmann, Michael ; Tsetlin, Victor I ; Makarov, Alexander A
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2019-07, Vol.8 (8), p.771
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ArticlesPeer ReviewedFull Text
Spatial Structure and Activity of Synthetic Fragments of Lynx1 and of Nicotinic Receptor Loop C Models
Author / Creator:Mineev, Konstantin S ; Kryukova, Elena V ; Kasheverov, Igor E ; Egorova, Natalia S ; Zhmak, Maxim N ; Ivanov, Igor A ; Senko, Dmitry A ; Feofanov, Alexey V ; Ignatova, Anastasia A ; Arseniev, Alexander S ; Utkin, Yuri N ; Tsetlin, Victor I
Publisher:Switzerland: MDPI
Journal title:Biomolecules (Basel, Switzerland), 2020-12, Vol.11 (1), p.1
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ArticlesPeer ReviewedFull Text
6-bromohypaphorine from marine nudibranch mollusk Hermissenda crassicornis is an agonist of human α7 nicotinic acetylcholine receptor
Author / Creator:Kasheverov, Igor E ; Shelukhina, Irina V ; Kudryavtsev, Denis S ; Makarieva, Tatyana N ; Spirova, Ekaterina N ; Guzii, Alla G ; Stonik, Valentin A ; Tsetlin, Victor I
Publisher:Switzerland: MDPI
Journal title:Marine drugs, 2015-03, Vol.13 (3), p.1255-1266
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ArticlesPeer ReviewedFull Text
Design of new α-conotoxins: from computer modeling to synthesis of potent cholinergic compounds
Author / Creator:Kasheverov, Igor E ; Zhmak, Maxim N ; Khruschov, Alexey Y ; Tsetlin, Victor I
Publisher:Switzerland: Molecular Diversity Preservation International
Journal title:Marine drugs, 2011, Vol.9 (10), p.1698-1714
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Scope and limitations of pseudoprolines as individual amino acids in peptide synthesis
Author / Creator:Senko, Dmitry A. ; Timofeev, Nikita D. ; Kasheverov, Igor E. ; Ivanov, Igor A.
Publisher:Vienna: Springer Vienna
Journal title:Amino acids, 2021-05, Vol.53 (5), p.665-671
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From crystal structure of α-conotoxin GIC in complex with Ac-AChBP to molecular determinants of its high selectivity for α3β2 nAChR
Author / Creator:Lin, Bo ; Xu, Manyu ; Zhu, Xiaopeng ; Wu, Yong ; Liu, Xi ; Zhangsun, Dongting ; Hu, Yuanyan ; Xiang, Shi-Hua ; Kasheverov, Igor E. ; Tsetlin, Victor I. ; Wang, Xinquan ; Luo, Sulan
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-03, Vol.6 (1), p.22349-22349, Article 22349
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Human Secreted Ly-6/uPAR Related Protein-1 (SLURP-1) Is a Selective Allosteric Antagonist of α7 Nicotinic Acetylcholine Receptor
Author / Creator:Lyukmanova, Ekaterina N ; Shulepko, Mikhail A ; Kudryavtsev, Denis ; Bychkov, Maxim L ; Kulbatskii, Dmitrii S ; Kasheverov, Igor E ; Astapova, Maria V ; Feofanov, Alexey V ; Thomsen, Morten S ; Mikkelsen, Jens D ; Shenkarev, Zakhar O ; Tsetlin, Victor I ; Dolgikh, Dmitry A ; Kirpichnikov, Mikhail P
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-02, Vol.11 (2), p.e0149733-e0149733
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High-Affinity α-Conotoxin PnIA Analogs Designed on the Basis of the Protein Surface Topography Method
Author / Creator:Kasheverov, Igor E. ; Chugunov, Anton O. ; Kudryavtsev, Denis S. ; Ivanov, Igor A. ; Zhmak, Maxim N. ; Shelukhina, Irina V. ; Spirova, Ekaterina N. ; Tabakmakher, Valentin M. ; Zelepuga, Elena A. ; Efremov, Roman G. ; Tsetlin, Victor I.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-11, Vol.6 (1), p.36848-36848, Article 36848
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Interaction of Synthetic Human SLURP-1 with the Nicotinic Acetylcholine Receptors
Author / Creator:Durek, Thomas ; Shelukhina, Irina V. ; Tae, Han-Shen ; Thongyoo, Panumart ; Spirova, Ekaterina N. ; Kudryavtsev, Denis S. ; Kasheverov, Igor E. ; Faure, Grazyna ; Corringer, Pierre-Jean ; Craik, David J. ; Adams, David J. ; Tsetlin, Victor I.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-11, Vol.7 (1), p.16606-11, Article 16606
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Complex approach for analysis of snake venom α-neurotoxins binding to HAP, the high-affinity peptide
Author / Creator:Kudryavtsev, Denis S. ; Tabakmakher, Valentin М. ; Budylin, Gleb S. ; Egorova, Natalia S. ; Efremov, Roman G. ; Ivanov, Igor A. ; Belukhina, Svetlana Yu ; Jegorov, Artjom V. ; Kasheverov, Igor E. ; Kryukova, Elena V. ; Shelukhina, Irina V. ; Shirshin, Evgeny A. ; Zhdanova, Nadezhda G. ; Zhmak, Maxim N. ; Tsetlin, Victor I.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-03, Vol.10 (1), p.3861, Article 3861
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6-Bromohypaphorine from Marine Nudibranch Mollusk Hermissenda crassicornis is an Agonist of Human alpha 7 Nicotinic Acetylcholine Receptor
Author / Creator:Kasheverov, Igor E ; Shelukhina, Irina V ; Kudryavtsev, Denis S ; Makarieva, Tatyana N ; Spirova, Ekaterina N ; Guzii, Alla G ; Stonik, Valentin A ; Tsetlin, Victor I
Journal title:Marine drugs, 2015-03, Vol.13 (3), p.1255-1266
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Showing 1 to 20 of 43 results

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Peptides from the Sea Anemone Metridium senile with Modified Inhibitor Cystine Knot (ICK) Fold Inhibit Nicotinic Acetylcholine Receptors

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Pancreatic and snake venom presynaptically active phospholipases A2 inhibit nicotinic acetylcholine receptors

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Analogs of 6-Bromohypaphorine with Increased Agonist Potency for α7 Nicotinic Receptor as Anti-Inflammatory Analgesic Agents

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Nicotinic Acetylcholine Receptors Are Novel Targets of APETx-like Toxins from the Sea Anemone Heteractis magnifica

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Inhibition of nicotinic acetylcholine receptors, a novel facet in the pleiotropic activities of snake venom phospholipases A2

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Curare alkaloids from Matis Dart Poison: Comparison with d-tubocurarine in interactions with nicotinic, 5-HT3 serotonin and GABAA receptors

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Arachidonoylcholine and Other Unsaturated Long-Chain Acylcholines Are Endogenous Modulators of the Acetylcholine Signaling System

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Makaluvamine G from the Marine Sponge Zyzzia fuliginosa Inhibits Muscle nAChR by Binding at the Orthosteric and Allosteric Sites

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Orthosteric and/or Allosteric Binding of α-Conotoxins to Nicotinic Acetylcholine Receptors and Their Models

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Isomerization of Asp7 in Beta-Amyloid Enhances Inhibition of the α7 Nicotinic Receptor and Promotes Neurotoxicity

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Spatial Structure and Activity of Synthetic Fragments of Lynx1 and of Nicotinic Receptor Loop C Models

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6-bromohypaphorine from marine nudibranch mollusk Hermissenda crassicornis is an agonist of human α7 nicotinic acetylcholine receptor

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Design of new α-conotoxins: from computer modeling to synthesis of potent cholinergic compounds

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Scope and limitations of pseudoprolines as individual amino acids in peptide synthesis

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From crystal structure of α-conotoxin GIC in complex with Ac-AChBP to molecular determinants of its high selectivity for α3β2 nAChR

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Human Secreted Ly-6/uPAR Related Protein-1 (SLURP-1) Is a Selective Allosteric Antagonist of α7 Nicotinic Acetylcholine Receptor

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High-Affinity α-Conotoxin PnIA Analogs Designed on the Basis of the Protein Surface Topography Method

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Interaction of Synthetic Human SLURP-1 with the Nicotinic Acetylcholine Receptors

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Complex approach for analysis of snake venom α-neurotoxins binding to HAP, the high-affinity peptide

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6-Bromohypaphorine from Marine Nudibranch Mollusk Hermissenda crassicornis is an Agonist of Human alpha 7 Nicotinic Acetylcholine Receptor

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