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ArticlesPeer ReviewedFull Text
OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin
Author / Creator:Chen, Ligong ; Shu, Yan ; Liang, Xiaomin ; Chen, Eugene C. ; Yee, Sook Wah ; Zur, Arik A. ; Li, Shuanglian ; Xu, Lu ; Keshari, Kayvan R. ; Lin, Michael J. ; Chien, Huan-Chieh ; Zhang, Youcai ; Morrissey, Kari M. ; Liu, Jason ; Ostrem, Jonathan ; Younger, Noah S. ; Kurhanewicz, John ; Shokat, Keven M. ; Ashrafi, Kaveh ; Giacomini, Kathleen M.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (27), p.9983-9988
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Untargeted pixel-by-pixel metabolite ratio imaging as a novel tool for biomedical discovery in mass spectrometry imaging
Author / Creator:Cheng, Huiyong ; Miller, Dawson ; Southwell, Nneka ; Porcari, Paola ; Fischer, Joshua L ; Taylor, Isobel ; Salbaum, J Michael ; Kappen, Claudia ; Hu, Fenghua ; Yang, Cha ; Keshari, Kayvan R ; Gross, Steven S ; D'Aurelio, Marilena ; Chen, Qiuying
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2025-03, Vol.13
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Imaging glutathione depletion in the rat brain using ascorbate-derived hyperpolarized MR and PET probes
Author / Creator:Qin, Hecong ; Carroll, Valerie N. ; Sriram, Renuka ; Villanueva-Meyer, Javier E. ; von Morze, Cornelius ; Wang, Zhen Jane ; Mutch, Christopher A. ; Keshari, Kayvan R. ; Flavell, Robert R. ; Kurhanewicz, John ; Wilson, David M.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-05, Vol.8 (1), p.7928-9, Article 7928
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Micro-Slab Coil Design for Hyperpolarized Metabolic Flux Analysis in Multiple Samples
Author / Creator:Lee, Geonhui ; Ruan, Thomas ; Wong, Claudia ; Deh, Kofi ; Abolarin, Alli ; Correa, Alexander ; Keshari, Kayvan R. ; Jeong, Sangmoo
Publisher:Switzerland: MDPI AG
Journal title:Bioengineering (Basel), 2022-12, Vol.10 (1), p.14
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Hyperpolarized 13C Spectroscopic Evaluation of Oxidative Stress in a Rodent Model of Steatohepatitis
Author / Creator:Wilson, David M. ; Di Gialleonardo, Valentina ; Wang, Zhen J. ; Carroll, Valerie ; Von Morze, Cornelius ; Taylor, Andrew ; Sai, Victor ; VanCriekinge, Mark ; Bok, Robert ; Ohliger, Michael A. ; Keshari, Kayvan R.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-04, Vol.7 (1), p.46014-46014, Article 46014
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Hyperpolarized [5-13C,4,4-²H₂,5-15N]-L-glutamine provides a means of annotating in vivo metabolic utilization of glutamine
Author / Creator:Eskandari, Roozbeh ; Kim, Nathaniel ; Mamakhanyan, Arsen ; Saoi, Michelle ; Zhang, Guannan ; Berishaj, Marjan ; Granlund, Kristin L. ; Poot, Alex J. ; Cross, Justin ; Thompson, Craig B. ; Keshari, Kayvan R.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2022-05, Vol.119 (19), p.1-8
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ArticlesPeer ReviewedFull Text
MRI of transmembrane water efflux in gliomas
Author / Creator:Ruan, Thomas ; Keshari, Kayvan R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature biomedical engineering, 2023-03, Vol.7 (3), p.195-196
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Hyaluronic acid fuels pancreatic cancer cell growth
Author / Creator:Kim, Peter K ; Halbrook, Christopher J ; Kerk, Samuel A ; Radyk, Megan ; Wisner, Stephanie ; Kremer, Daniel M ; Sajjakulnukit, Peter ; Andren, Anthony ; Hou, Sean W ; Trivedi, Ayush ; Thurston, Galloway ; Anand, Abhinav ; Yan, Liang ; Salamanca-Cardona, Lucia ; Welling, Samuel D ; Zhang, Li ; Pratt, Matthew R ; Keshari, Kayvan R ; Ying, Haoqiang ; Lyssiotis, Costas A
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2021-12, Vol.10
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ArticlesPeer ReviewedFull Text
Hyperpolarized 13C dehydroascorbate as an endogenous redox sensor for in vivo metabolic imaging
Author / Creator:Keshari, Kayvan R ; Kurhanewicz, John ; Bok, Robert ; Larson, Peder E. Z ; Vigneron, Daniel B ; Wilson, David M
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-11, Vol.108 (46), p.18606-18611
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Non-invasive PET Imaging of PARP1 Expression in Glioblastoma Models
Author / Creator:Carney, Brandon ; Carlucci, Giuseppe ; Salinas, Beatriz ; Di Gialleonardo, Valentina ; Kossatz, Susanne ; Vansteene, Axel ; Longo, Valerie A. ; Bolaender, Alexander ; Chiosis, Gabriela ; Keshari, Kayvan R. ; Weber, Wolfgang A. ; Reiner, Thomas
Publisher:New York: Springer US
Journal title:Molecular imaging and biology, 2016-06, Vol.18 (3), p.386-392
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ArticlesPeer ReviewedFull Text
Cancer Metabolism and Tumor Heterogeneity: Imaging Perspectives Using MR Imaging and Spectroscopy
Author / Creator:Lin, Gigin ; Park, Jae Mo ; Keshari, Kayvan R.
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:Contrast media and molecular imaging, 2017-01, Vol.2017 (2017), p.1-18
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Sampling Hyperpolarized Molecules Utilizing a 1 Tesla Permanent Magnetic Field
Author / Creator:Tee, Sui Seng ; DiGialleonardo, Valentina ; Eskandari, Roozbeh ; Jeong, Sangmoo ; Granlund, Kristin L. ; Miloushev, Vesselin ; Poot, Alex J. ; Truong, Steven ; Alvarez, Julio A. ; Aldeborgh, Hannah N. ; Keshari, Kayvan R.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-09, Vol.6 (1), p.32846-32846, Article 32846
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Elevated Tumor Lactate and Efflux in High-grade Prostate Cancer demonstrated by Hyperpolarized 13C Magnetic Resonance Spectroscopy of Prostate Tissue Slice Cultures
Author / Creator:Sriram, Renuka ; Van Criekinge, Mark ; DeLos Santos, Justin ; Ahamed, Fayyaz ; Qin, Hecong ; Nolley, Rosalie ; DeLos Santos, Romelyn ; Tabatabai, Z. Laura ; Bok, Robert A. ; Keshari, Kayvan R. ; Vigneron, Daniel B. ; Peehl, Donna M. ; Kurhanewicz, John
Publisher:MDPI
Journal title:Cancers, 2020-02, Vol.12 (3), p.537
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13C-labeled biochemical probes for the study of cancer metabolism with dynamic nuclear polarization-enhanced magnetic resonance imaging
Author / Creator:Salamanca-Cardona, Lucia ; Keshari, Kayvan R.
Publisher:London: BioMed Central Ltd
Journal title:Cancer & metabolism, 2015-09, Vol.3 (1), Article 9
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Effect of Oxygen Concentration on Viability and Metabolism in a Fluidized-Bed Bioartificial Liver Using 31P and 13C NMR Spectroscopy
Author / Creator:Jeffries, Rex E. ; Gamcsik, Michael P. ; Keshari, Kayvan R. ; Pediaditakis, Peter ; Tikunov, Andrey P. ; Young, Gregory B. ; Lee, Haakil ; Watkins, Paul B. ; Macdonald, Jeffrey M.
Publisher:United States: Mary Ann Liebert, Inc
Journal title:Tissue engineering. Part C, Methods, 2013-02, Vol.19 (2), p.93-100
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ArticlesPeer ReviewedFull Text
Untargeted pixel-by-pixel metabolite ratio imaging as a novel tool for biomedical discovery in mass spectrometry imaging
Author / Creator:Cheng, Huiyong ; Miller, Dawson ; Southwell, Nneka ; Porcari, Paola ; Fischer, Joshua L ; Taylor, Isobel ; Salbaum, J Michael ; Kappen, Claudia ; Hu, Fenghua ; Yang, Cha ; Keshari, Kayvan R ; Gross, Steven S ; D'Aurelio, Marilena ; Chen, Qiuying
Journal title:eLife, 2025-03, Vol.13
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Hyaluronic Acid Fuels Pancreatic Cancer Growth
Author / Creator:Kim, Peter K ; Halbrook, Christopher J ; Kerk, Samuel A ; Wisner, Stephanie ; Kremer, Daniel M ; Sajjakulnukit, Peter ; Hou, Sean W ; Galloway Thurston ; Anand, Abhinav ; Liang, Yan ; Salamanca-Cardona, Lucia ; Welling, Samuel D ; Zhang, Li ; Pratt, Matthew R ; Keshari, Kayvan R ; Haoqiang Ying ; Lyssiotis, Costas A
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-09
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Elevated Tumor Lactate and Efflux in High-grade Prostate Cancer demonstrated by Hyperpolarized 13 C Magnetic Resonance Spectroscopy of Prostate Tissue Slice Cultures
Author / Creator:Sriram, Renuka ; Van Criekinge, Mark ; DeLos Santos, Justin ; Ahamed, Fayyaz ; Qin, Hecong ; Nolley, Rosalie ; Santos, Romelyn DeLos ; Tabatabai, Z Laura ; Bok, Robert A ; Keshari, Kayvan R ; Vigneron, Daniel B ; Peehl, Donna M ; Kurhanewicz, John
Publisher:Switzerland
Journal title:Cancers, 2020-02, Vol.12 (3)
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ArticlesPeer ReviewedFull Text
(13)C-labeled biochemical probes for the study of cancer metabolism with dynamic nuclear polarization-enhanced magnetic resonance imaging
Author / Creator:Salamanca-Cardona, Lucia ; Keshari, Kayvan R
Publisher:England
Journal title:Cancer & metabolism, 2015, Vol.3, p.9-9
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ArticlesPeer ReviewedFull Text
Hyperpolarized ^sup 13^C dehydroascorbate as an endogenous redox sensor for in vivo metabolic imaging
Author / Creator:Keshari, Kayvan R ; Kurhanewicz, John ; Bok, Robert ; Larson, Peder E Z ; Vigneron, Daniel B ; Wilson, David M
Publisher:Washington: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-11, Vol.108 (46), p.18606
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Showing 1 to 20 of 25 results

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OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin

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Untargeted pixel-by-pixel metabolite ratio imaging as a novel tool for biomedical discovery in mass spectrometry imaging

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Imaging glutathione depletion in the rat brain using ascorbate-derived hyperpolarized MR and PET probes

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Micro-Slab Coil Design for Hyperpolarized Metabolic Flux Analysis in Multiple Samples

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Hyperpolarized 13C Spectroscopic Evaluation of Oxidative Stress in a Rodent Model of Steatohepatitis

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Hyperpolarized [5-13C,4,4-²H₂,5-15N]-L-glutamine provides a means of annotating in vivo metabolic utilization of glutamine

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MRI of transmembrane water efflux in gliomas

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Hyaluronic acid fuels pancreatic cancer cell growth

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Hyperpolarized 13C dehydroascorbate as an endogenous redox sensor for in vivo metabolic imaging

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Non-invasive PET Imaging of PARP1 Expression in Glioblastoma Models

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Cancer Metabolism and Tumor Heterogeneity: Imaging Perspectives Using MR Imaging and Spectroscopy

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Sampling Hyperpolarized Molecules Utilizing a 1 Tesla Permanent Magnetic Field

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Elevated Tumor Lactate and Efflux in High-grade Prostate Cancer demonstrated by Hyperpolarized 13C Magnetic Resonance Spectroscopy of Prostate Tissue Slice Cultures

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13C-labeled biochemical probes for the study of cancer metabolism with dynamic nuclear polarization-enhanced magnetic resonance imaging

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Effect of Oxygen Concentration on Viability and Metabolism in a Fluidized-Bed Bioartificial Liver Using 31P and 13C NMR Spectroscopy

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Untargeted pixel-by-pixel metabolite ratio imaging as a novel tool for biomedical discovery in mass spectrometry imaging

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Hyaluronic Acid Fuels Pancreatic Cancer Growth

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Elevated Tumor Lactate and Efflux in High-grade Prostate Cancer demonstrated by Hyperpolarized 13 C Magnetic Resonance Spectroscopy of Prostate Tissue Slice Cultures

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(13)C-labeled biochemical probes for the study of cancer metabolism with dynamic nuclear polarization-enhanced magnetic resonance imaging

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Hyperpolarized ^sup 13^C dehydroascorbate as an endogenous redox sensor for in vivo metabolic imaging

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