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Reference EntriesFull Text
Kieft, Jeffrey S
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: ING-KNI, 2022, p.5969-5969
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Kieft, Jeffrey S
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: ING-KNI, 2021, p.5948-5948
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ArticlesPeer ReviewedFull Text
The Structural Basis of Pathogenic Subgenomic Flavivirus RNA (sfRNA) Production
Author / Creator:Chapman, Erich G. ; Costantino, David A. ; Rabe, Jennifer L. ; Moon, Stephanie L. ; Wilusz, Jeffrey ; Nix, Jay C. ; Kieft, Jeffrey S.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2014-04, Vol.344 (6181), p.307-310
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PPM1D suppresses p53-dependent transactivation and cell death by inhibiting the Integrated Stress Response
Author / Creator:Andrysik, Zdenek ; Sullivan, Kelly D. ; Kieft, Jeffrey S. ; Espinosa, Joaquin M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-12, Vol.13 (1), p.7400-16, Article 7400
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Recognition of non-CpG repeats in Alu and ribosomal RNAs by the Z-RNA binding domain of ADAR1 induces A-Z junctions
Author / Creator:Nichols, Parker J. ; Bevers, Shaun ; Henen, Morkos ; Kieft, Jeffrey S. ; Vicens, Quentin ; Vögeli, Beat
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-02, Vol.12 (1), p.793-793, Article 793
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ArticlesPeer ReviewedFull Text
RNA structures that resist degradation by Xrn1 produce a pathogenic Dengue virus RNA
Author / Creator:Chapman, Erich G ; Moon, Stephanie L ; Wilusz, Jeffrey ; Kieft, Jeffrey S
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2014-04, Vol.3, p.e01892
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ArticlesPeer ReviewedFull Text
A folded viral noncoding RNA blocks host cell exoribonucleases through a conformationally dynamic RNA structure
Author / Creator:Steckelberg, Anna-Lena ; Akiyama, Benjamin M. ; Costantino, David A. ; Sit, Tim L. ; Nix, Jay C. ; Kieft, Jeffrey S.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-06, Vol.115 (25), p.6404-6409
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ArticlesPeer ReviewedFull Text
Mechanism and structural diversity of exoribonuclease-resistant RNA structures in flaviviral RNAs
Author / Creator:MacFadden, Andrea ; O’Donoghue, Zoe ; Silva, Patricia A. G. C. ; Chapman, Erich G. ; Olsthoorn, René C. ; Sterken, Mark G. ; Pijlman, Gorben P. ; Bredenbeek, Peter J. ; Kieft, Jeffrey S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-01, Vol.9 (1), p.119-119, Article 119
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ArticlesPeer ReviewedFull Text
Translation initiation by the hepatitis C virus IRES requires eIF1A and ribosomal complex remodeling
Author / Creator:Jaafar, Zane A ; Oguro, Akihiro ; Nakamura, Yoshikazu ; Kieft, Jeffrey S
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2016-12, Vol.5
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Therapeutic resistance in acute myeloid leukemia cells is mediated by a novel ATM/mTOR pathway regulating oxidative phosphorylation
Author / Creator:Park, Hae J ; Gregory, Mark A ; Zaberezhnyy, Vadym ; Goodspeed, Andrew ; Jordan, Craig T ; Kieft, Jeffrey S ; DeGregori, James
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2022-10, Vol.11
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Initiation of translation in bacteria by a structured eukaryotic IRES RNA
Author / Creator:Colussi, Timothy M. ; Costantino, David A. ; Zhu, Jianyu ; Donohue, John Paul ; Korostelev, Andrei A. ; Jaafar, Zane A. ; Plank, Terra-Dawn M. ; Noller, Harry F. ; Kieft, Jeffrey S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-03, Vol.519 (7541), p.110-113
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ArticlesPeer ReviewedFull Text
HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation
Author / Creator:Filbin, Megan E ; Vollmar, Breanna S ; Shi, Dan ; Gonen, Tamir ; Kieft, Jeffrey S
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2013-02, Vol.20 (2), p.150-158
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ArticlesPeer ReviewedFull Text
Structural Basis for Ribosome Recruitment and Manipulation by a Viral IRES RNA
Author / Creator:Pfingsten, Jennifer S ; Costantino, David A ; Kieft, Jeffrey S
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2006-12, Vol.314 (5804), p.1450-1454
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ArticlesPeer ReviewedFull Text
Ribosome-induced RNA conformational changes in a viral 3′-UTR sense and regulate translation levels
Author / Creator:Hartwick, Erik W. ; Costantino, David A. ; MacFadden, Andrea ; Nix, Jay C. ; Tian, Siqi ; Das, Rhiju ; Kieft, Jeffrey S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-11, Vol.9 (1), p.5074-12, Article 5074
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ArticlesPeer ReviewedFull Text
Viral RNA structure-based strategies to manipulate translation
Author / Creator:Jaafar, Zane A. ; Kieft, Jeffrey S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Microbiology, 2019-02, Vol.17 (2), p.110-123
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Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome
Author / Creator:Zhu, Jianyu ; Korostelev, Andrei ; Costantino, David A. ; Donohue, John P. ; Noller, Harry F. ; Kieft, Jeffrey S.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-02, Vol.108 (5), p.1839-1844
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A dynamic RNA loop in an IRES affects multiple steps of elongation factor-mediated translation initiation
Author / Creator:Ruehle, Marisa D ; Zhang, Haibo ; Sheridan, Ryan M ; Mitra, Somdeb ; Chen, Yuanwei ; Gonzalez, Ruben L ; Cooperman, Barry S ; Kieft, Jeffrey S
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2015-11, Vol.4
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ArticlesPeer ReviewedFull Text
Crystal structure of an RNA tertiary domain essential to HCV IRES-mediated translation initiation
Author / Creator:Kieft, Jeffrey S. ; Zhou, Kaihong ; Grech, Angie ; Jubin, Ronald ; Doudna, Jennifer A.
Publisher:New York: Nature Publishing Group US
Journal title:Nature Structural Biology, 2002-05, Vol.9 (5), p.370-374
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ArticlesPeer ReviewedFull Text
Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease
Author / Creator:Akiyama, Benjamin M. ; Laurence, Hannah M. ; Massey, Aaron R. ; Costantino, David A. ; Xie, Xuping ; Yang, Yujiao ; Shi, Pei-Yong ; Nix, Jay C. ; Beckham, J. David ; Kieft, Jeffrey S.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2016-12, Vol.354 (6316), p.1148-1152
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ArticlesPeer ReviewedFull Text
Linking Α to Ω: diverse and dynamic RNA-based mechanisms to regulate gene expression by 5′-to-3′ communication [version 1; peer review: 2 approved]
Author / Creator:Filbin, Megan E ; Kieft, Jeffrey S
Publisher:England: Faculty of 1000 Ltd
Journal title:F1000 research, 2016, Vol.5, p.2037
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Kieft, Jeffrey S

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Kieft, Jeffrey S

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The Structural Basis of Pathogenic Subgenomic Flavivirus RNA (sfRNA) Production

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PPM1D suppresses p53-dependent transactivation and cell death by inhibiting the Integrated Stress Response

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Recognition of non-CpG repeats in Alu and ribosomal RNAs by the Z-RNA binding domain of ADAR1 induces A-Z junctions

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RNA structures that resist degradation by Xrn1 produce a pathogenic Dengue virus RNA

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A folded viral noncoding RNA blocks host cell exoribonucleases through a conformationally dynamic RNA structure

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Mechanism and structural diversity of exoribonuclease-resistant RNA structures in flaviviral RNAs

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Translation initiation by the hepatitis C virus IRES requires eIF1A and ribosomal complex remodeling

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Therapeutic resistance in acute myeloid leukemia cells is mediated by a novel ATM/mTOR pathway regulating oxidative phosphorylation

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Initiation of translation in bacteria by a structured eukaryotic IRES RNA

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HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation

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Structural Basis for Ribosome Recruitment and Manipulation by a Viral IRES RNA

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Ribosome-induced RNA conformational changes in a viral 3′-UTR sense and regulate translation levels

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Viral RNA structure-based strategies to manipulate translation

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Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome

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A dynamic RNA loop in an IRES affects multiple steps of elongation factor-mediated translation initiation

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Crystal structure of an RNA tertiary domain essential to HCV IRES-mediated translation initiation

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Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease

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Linking Α to Ω: diverse and dynamic RNA-based mechanisms to regulate gene expression by 5′-to-3′ communication [version 1; peer review: 2 approved]

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