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ArticlesPeer ReviewedFull Text
T cell cholesterol efflux suppresses apoptosis and senescence and increases atherosclerosis in middle aged mice
Author / Creator:Bazioti, Venetia ; La Rose, Anouk M. ; Maassen, Sjors ; Bianchi, Frans ; de Boer, Rinse ; Halmos, Benedek ; Dabral, Deepti ; Guilbaud, Emma ; Flohr-Svendsen, Arthur ; Groenen, Anouk G. ; Marmolejo-Garza, Alejandro ; Koster, Mirjam H. ; Kloosterhuis, Niels J. ; Havinga, Rick ; Pranger, Alle T. ; Langelaar-Makkinje, Miriam ; de Bruin, Alain ; van de Sluis, Bart ; Kohan, Alison B. ; Yvan-Charvet, Laurent ; van den Bogaart, Geert ; Westerterp, Marit
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-07, Vol.13 (1), p.3799-3799, Article 3799
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The impact of a humanized bile acid composition on atherosclerosis development in hypercholesterolaemic Cyp2c70 knockout mice
Author / Creator:Yntema, Tess ; Eijgenraam, Tim R. ; Kloosterhuis, Niels J. ; Havinga, Rick ; Koster, Mirjam H. ; Hovingh, Milaine V. ; de Boer, Jan Freark ; Koonen, Debby P. Y. ; Kuipers, Folkert
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-01, Vol.15 (1), p.2100-11, Article 2100
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ArticlesPeer ReviewedFull Text
CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL
Author / Creator:Bartuzi, Paulina ; Billadeau, Daniel D. ; Favier, Robert ; Rong, Shunxing ; Dekker, Daphne ; Fedoseienko, Alina ; Fieten, Hille ; Wijers, Melinde ; Levels, Johannes H. ; Huijkman, Nicolette ; Kloosterhuis, Niels ; van der Molen, Henk ; Brufau, Gemma ; Groen, Albert K. ; Elliott, Alison M. ; Kuivenhoven, Jan Albert ; Plecko, Barbara ; Grangl, Gernot ; McGaughran, Julie ; Horton, Jay D. ; Burstein, Ezra ; Hofker, Marten H. ; van de Sluis, Bart
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-03, Vol.7 (1), p.10961-10961, Article 10961
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Mice with a deficiency in Peroxisomal Membrane Protein 4 (PXMP4) display mild changes in hepatic lipid metabolism
Author / Creator:Blankestijn, Maaike ; Bloks, Vincent W. ; Struik, Dicky ; Huijkman, Nicolette ; Kloosterhuis, Niels ; Wolters, Justina C. ; Wanders, Ronald J. A. ; Vaz, Frédéric M. ; Islinger, Markus ; Kuipers, Folkert ; van de Sluis, Bart ; Groen, Albert K. ; Verkade, Henkjan J. ; Jonker, Johan W.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-02, Vol.12 (1), p.2512-2512, Article 2512
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ArticlesPeer ReviewedFull Text
Chemokine-Like Receptor 1 Deficiency Does Not Affect the Development of Insulin Resistance and Nonalcoholic Fatty Liver Disease in Mice
Author / Creator:Gruben, Nanda ; Aparicio Vergara, Marcela ; Kloosterhuis, Niels J. ; van der Molen, Henk ; Stoelwinder, Stefan ; Youssef, Sameh ; de Bruin, Alain ; Delsing, Dianne J. ; Kuivenhoven, Jan Albert ; van de Sluis, Bart ; Hofker, Marten H. ; Koonen, Debby P. Y.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-04, Vol.9 (4), p.e96345
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ArticlesPeer ReviewedFull Text
Human Primary Adipocytes Exhibit Immune Cell Function: Adipocytes Prime Inflammation Independent of Macrophages
Author / Creator:Meijer, Kees ; de Vries, Marcel ; Al-Lahham, Saad ; Bruinenberg, Marcel ; Weening, Desirée ; Dijkstra, Martijn ; Kloosterhuis, Niels ; van der Leij, Roelof Jan ; van der Want, Han ; Kroesen, Bart-Jan ; Vonk, Roel ; Rezaee, Farhad
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-03, Vol.6 (3), p.e17154-e17154
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ArticlesPeer ReviewedFull Text
Liver-Specific Commd1 Knockout Mice Are Susceptible to Hepatic Copper Accumulation
Author / Creator:Vonk, Willianne I. M. ; Bartuzi, Paulina ; de Bie, Prim ; Kloosterhuis, Niels ; Wichers, Catharina G. K. ; Berger, Ruud ; Haywood, Susan ; Klomp, Leo W. J. ; Wijmenga, Cisca ; van de Sluis, Bart
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-12, Vol.6 (12), p.e29183-e29183
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ArticlesPeer ReviewedFull Text
Cholesterol-Induced Hepatic Inflammation Does Not Underlie the Predisposition to Insulin Resistance in Dyslipidemic Female LDL Receptor Knockout Mice
Author / Creator:Kuivenhoven, Jan Albert ; Koonen, Debby P. Y. ; Hofker, Marten H. ; Shiri-Sverdlov, Ronit ; Houten, Sander M. ; Havinga, Rick ; Sheedfar, Fareeba ; Schreurs, Marijke ; Kloosterhuis, Niels J. ; Funke, Anouk ; Gruben, Nanda ; van de Sluis, Bart
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:Journal of diabetes research, 2015-01, Vol.2015 (2015), p.1-12
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ArticlesPeer ReviewedFull Text
Selective Hepatic Cbs Knockout Aggravates Liver Damage, Endothelial Dysfunction and ROS Stress in Mice Fed a Western Diet
Author / Creator:Lambooy, Sebastiaan ; Heida, Andries ; Joschko, Christian ; Nakladal, Dalibor ; van Buiten, Azuwerus ; Kloosterhuis, Niels ; Huijkman, Nicolette ; Gerding, Albert ; van de Sluis, Bart ; Henning, Robert ; Deelman, Leo
Publisher:Switzerland: MDPI
Journal title:International journal of molecular sciences, 2023-04, Vol.24 (8), p.7019
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ArticlesPeer ReviewedFull Text
Selective Hepatic ICbs/I Knockout Aggravates Liver Damage, Endothelial Dysfunction and ROS Stress in Mice Fed a Western Diet
Author / Creator:Lambooy, Sebastiaan ; Heida, Andries ; Joschko, Christian ; Nakladal, Dalibor ; van Buiten, Azuwerus ; Kloosterhuis, Niels ; Huijkman, Nicolette ; Gerding, Albert ; van de Sluis, Bart ; Henning, Robert ; Deelman, Leo
Publisher:MDPI AG
Journal title:International journal of molecular sciences, 2023-04, Vol.24 (8)
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ArticlesPeer ReviewedFull Text
Chemokine-Like Receptor 1 Deficiency Does Not Affect the Development of Insulin Resistance and Nonalcoholic Fatty Liver Disease in Mice: e96345
Author / Creator:Gruben, Nanda ; Vergara, Marcela Aparicio ; Kloosterhuis, Niels J ; Molen, Henk vander ; Stoelwinder, Stefan ; Youssef, Sameh ; Bruin, Alain de ; Delsing, Dianne J ; Kuivenhoven, Jan Albert ; Sluis, Bart vande
Journal title:PloS one, 2014-04, Vol.9 (4)
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ArticlesFull Text
T cell cholesterol efflux suppresses apoptosis and senescence and increases atherosclerosis in middle aged mice
Author / Creator:Bazioti, Venetia ; La Rose, Anouk M ; Maassen, Sjors ; Bianchi, Frans ; De Boer, Rinse ; Guilbaud, Emma ; Arthur Flohr Svendsen ; Groenen, Anouk G ; Marmolejo-Garza, Alejandro ; Koster, Mirjam H ; Kloosterhuis, Niels J ; Pranger, Alle T ; Langelaar-Makkinje, Miriam ; De Bruin, Alain ; Van De Sluis, Bart ; Alison Bloom Kohan ; Yvan-Charvet, Laurent ; Geert Van Den Bogaart ; Westerterp, Marit
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2022-05
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T cell cholesterol efflux suppresses apoptosis and senescence and increases atherosclerosis in middle aged mice

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The impact of a humanized bile acid composition on atherosclerosis development in hypercholesterolaemic Cyp2c70 knockout mice

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CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL

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Mice with a deficiency in Peroxisomal Membrane Protein 4 (PXMP4) display mild changes in hepatic lipid metabolism

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Chemokine-Like Receptor 1 Deficiency Does Not Affect the Development of Insulin Resistance and Nonalcoholic Fatty Liver Disease in Mice

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Human Primary Adipocytes Exhibit Immune Cell Function: Adipocytes Prime Inflammation Independent of Macrophages

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Liver-Specific Commd1 Knockout Mice Are Susceptible to Hepatic Copper Accumulation

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Cholesterol-Induced Hepatic Inflammation Does Not Underlie the Predisposition to Insulin Resistance in Dyslipidemic Female LDL Receptor Knockout Mice

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Selective Hepatic Cbs Knockout Aggravates Liver Damage, Endothelial Dysfunction and ROS Stress in Mice Fed a Western Diet

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Selective Hepatic ICbs/I Knockout Aggravates Liver Damage, Endothelial Dysfunction and ROS Stress in Mice Fed a Western Diet

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Chemokine-Like Receptor 1 Deficiency Does Not Affect the Development of Insulin Resistance and Nonalcoholic Fatty Liver Disease in Mice: e96345

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T cell cholesterol efflux suppresses apoptosis and senescence and increases atherosclerosis in middle aged mice

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