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ArticlesPeer ReviewedFull Text
Translatome proteomics identifies autophagy as a resistance mechanism to on-target FLT3 inhibitors in acute myeloid leukemia
Author / Creator:Koschade, Sebastian E. ; Klann, Kevin ; Shaid, Shabnam ; Vick, Binje ; Stratmann, Jan A. ; Thölken, Marlyn ; Meyer, Laura M. ; Nguyen, The Duy ; Campe, Julia ; Moser, Laura M. ; Hock, Susanna ; Baker, Fatima ; Meyer, Christian T. ; Wempe, Frank ; Serve, Hubert ; Ullrich, Evelyn ; Jeremias, Irmela ; Münch, Christian ; Brandts, Christian H.
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2022-10, Vol.36 (10), p.2396-2407
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ArticlesPeer ReviewedFull Text
Diagnostic yield, indications, and outcomes of cranial imaging in AML patients admitted for intensive induction or consolidation chemotherapy: a single-center experience
Author / Creator:Koschade, Sebastian E. ; Stratmann, Jan A. ; Zeiner, Pia S. ; Finkelmeier, Fabian ; Chromik, Jörg ; Steffen, Björn ; Serve, Hubert ; Brandts, Christian H. ; Ballo, Olivier
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Annals of hematology, 2023-05, Vol.102 (5), p.1045-1052
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ArticlesPeer ReviewedFull Text
The notch target gene HEYL modulates metastasis forming capacity of colorectal cancer patient-derived spheroid cells in vivo
Author / Creator:Weber, Sarah ; Koschade, Sebastian E. ; Hoffmann, Christopher M. ; Dubash, Taronish D. ; Giessler, Klara M. ; Dieter, Sebastian M. ; Herbst, Friederike ; Glimm, Hanno ; Ball, Claudia R.
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2019-12, Vol.19 (1), p.1181-1181, Article 1181
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ArticlesPeer ReviewedFull Text
PDP1 is a key metabolic gatekeeper and modulator of drug resistance in FLT3-ITD-positive acute myeloid leukemia
Author / Creator:Alshamleh, Islam ; Kurrle, Nina ; Makowka, Philipp ; Bhayadia, Raj ; Kumar, Rahul ; Süsser, Sebastian ; Seibert, Marcel ; Ludig, Damian ; Wolf, Sebastian ; Koschade, Sebastian E. ; Stoschek, Karoline ; Kreitz, Johanna ; Fuhrmann, Dominik C. ; Toenges, Rosa ; Notaro, Marco ; Comoglio, Federico ; Schuringa, Jan Jacob ; Berg, Tobias ; Brüne, Bernhard ; Krause, Daniela S. ; Klusmann, Jan-Henning ; Oellerich, Thomas ; Schnütgen, Frank ; Schwalbe, Harald ; Serve, Hubert
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2023-12, Vol.37 (12), p.2367-2382
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ArticlesPeer ReviewedFull Text
Correction: Translatome proteomics identifies autophagy as a resistance mechanism to on-target FLT3 inhibitors in acute myeloid leukemia
Author / Creator:Koschade, Sebastian E. ; Klann, Kevin ; Shaid, Shabnam ; Vick, Binje ; Stratmann, Jan A. ; Thölken, Marlyn ; Meyer, Laura M. ; Nguyen, The Duy ; Campe, Julia ; Moser, Laura M. ; Hock, Susanna ; Baker, Fatima ; Meyer, Christian T. ; Wempe, Frank ; Serve, Hubert ; Ullrich, Evelyn ; Jeremias, Irmela ; Münch, Christian ; Brandts, Christian H.
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2022-12, Vol.36 (12), p.2950-2950
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ArticlesPeer ReviewedFull Text
Relapse surveillance of acute myeloid leukemia patients in first remission after consolidation chemotherapy: diagnostic value of regular bone marrow aspirations
Author / Creator:Koschade, Sebastian E. ; Stratmann, Jan A. ; Finkelmeier, Fabian ; Wagner, Sebastian ; Chromik, Jörg ; Steffen, Björn ; Serve, Hubert ; Brandts, Christian H. ; Ballo, Olivier
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Annals of hematology, 2022-08, Vol.101 (8), p.1703-1710
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ArticlesPeer ReviewedFull Text
Colonization with multi-drug-resistant organisms negatively impacts survival in patients with non-small cell lung cancer
Author / Creator:Stratmann, Jan A. ; Lacko, Raphael ; Ballo, Olivier ; Shaid, Shabnam ; Gleiber, Wolfgang ; Vehreschild, Maria J. G. T. ; Wichelhaus, Thomas ; Reinheimer, Claudia ; Göttig, Stephan ; Kempf, Volkhard A. J. ; Kleine, Peter ; Stera, Susanne ; Brandts, Christian ; Sebastian, Martin ; Koschade, Sebastian
Publisher:United States: Public Library of Science
Journal title:PloS one, 2020-11, Vol.15 (11), p.e0242544-e0242544
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ArticlesPeer ReviewedFull Text
The MYC-Regulated RNA-Binding Proteins hnRNPC and LARP1 Are Drivers of Multiple Myeloma Cell Growth and Disease Progression and Negatively Predict Patient Survival
Author / Creator:Seibert, Marcel ; Koschade, Sebastian E. ; Stolp, Verena ; Häupl, Björn ; Wempe, Frank ; Serve, Hubert ; Kurrle, Nina ; Schnütgen, Frank ; von Metzler, Ivana
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2023-11, Vol.15 (23), p.5508
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ArticlesPeer ReviewedFull Text
Fluid overload is associated with increased 90-day mortality in AML patients undergoing induction chemotherapy
Author / Creator:Ballo, Olivier ; Eladly, Fagr ; Koschade, Sebastian ; Büttner, Stefan ; Stratmann, Jan Alexander ; Brunnberg, Uta ; Kreisel, Eva-Maria ; Frank, Franziska ; Wagner, Sebastian ; Steffen, Björn ; Serve, Hubert ; Finkelmeier, Fabian ; Brandts, Christian H.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Annals of hematology, 2021-10, Vol.100 (10), p.2603-2611
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ArticlesPeer ReviewedFull Text
Metabolic Rewiring Is Essential for AML Cell Survival to Overcome Autophagy Inhibition by Loss of ATG3
Author / Creator:Baker, Fatima ; Polat, Ibrahim H. ; Abou-El-Ardat, Khalil ; Alshamleh, Islam ; Thoelken, Marlyn ; Hymon, Daniel ; Gubas, Andrea ; Koschade, Sebastian E. ; Vischedyk, Jonas B. ; Kaulich, Manuel ; Schwalbe, Harald ; Shaid, Shabnam ; Brandts, Christian H.
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2021-12, Vol.13 (23), p.6142
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ArticlesPeer ReviewedFull Text
Bone Marrow Assessment in Liver Cirrhosis Patients with Otherwise Unexplained Peripheral Blood Cytopenia
Author / Creator:Koschade, Sebastian E. ; Moser, Laura M. ; Sokolovskiy, Artur ; Michael, Florian A. ; Serve, Hubert ; Brandts, Christian H. ; Finkelmeier, Fabian ; Zeuzem, Stefan ; Trebicka, Jonel ; Ferstl, Philip ; Ballo, Olivier
Publisher:Switzerland: MDPI AG
Journal title:Journal of clinical medicine, 2023-06, Vol.12 (13), p.4373
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ArticlesFull Text
Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2)
Author / Creator:Chaikuad, Apirat ; Koschade, Sebastian E ; Stolz, Alexandra ; Zivkovic, Katarina ; Shaid, Shabnam ; Pohl, Christian ; Ren, Huiyu ; Lambert, Lester J ; Cosford, Nicholas Dp ; Brandts, Christian H ; Knapp, Stefan
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2019-02
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ArticlesPeer ReviewedFull Text
Clinical and genetic characterization of de novo double-hit B cell precursor leukemia/lymphoma
Author / Creator:Stratmann, Jan A. ; von Rose, Aaron Becker ; Koschade, Sebastian ; Wendelin, Knut ; Köhler, Friedemann ; Heinsch, Michael ; Schiller, Kilian ; Haferlach, Claudia ; Wattad, Mohamed ; Rieder, Harald ; Serve, Hubert ; Gökbuget, Nicola ; Steffen, Björn
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Annals of hematology, 2019-03, Vol.98 (3), p.647-656
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Translatome proteomics identifies autophagy as a resistance mechanism to on-target FLT3 inhibitors in acute myeloid leukemia

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Diagnostic yield, indications, and outcomes of cranial imaging in AML patients admitted for intensive induction or consolidation chemotherapy: a single-center experience

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The notch target gene HEYL modulates metastasis forming capacity of colorectal cancer patient-derived spheroid cells in vivo

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PDP1 is a key metabolic gatekeeper and modulator of drug resistance in FLT3-ITD-positive acute myeloid leukemia

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Correction: Translatome proteomics identifies autophagy as a resistance mechanism to on-target FLT3 inhibitors in acute myeloid leukemia

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Relapse surveillance of acute myeloid leukemia patients in first remission after consolidation chemotherapy: diagnostic value of regular bone marrow aspirations

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Colonization with multi-drug-resistant organisms negatively impacts survival in patients with non-small cell lung cancer

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The MYC-Regulated RNA-Binding Proteins hnRNPC and LARP1 Are Drivers of Multiple Myeloma Cell Growth and Disease Progression and Negatively Predict Patient Survival

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Fluid overload is associated with increased 90-day mortality in AML patients undergoing induction chemotherapy

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Metabolic Rewiring Is Essential for AML Cell Survival to Overcome Autophagy Inhibition by Loss of ATG3

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Bone Marrow Assessment in Liver Cirrhosis Patients with Otherwise Unexplained Peripheral Blood Cytopenia

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Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2)

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Clinical and genetic characterization of de novo double-hit B cell precursor leukemia/lymphoma

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