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ArticlesPeer ReviewedFull Text
Open Systems Pharmacology Community—An Open Access, Open Source, Open Science Approach to Modeling and Simulation in Pharmaceutical Sciences
Author / Creator:Lippert, Jörg ; Burghaus, Rolf ; Edginton, Andrea ; Frechen, Sebastian ; Karlsson, Mats ; Kovar, Andreas ; Lehr, Thorsten ; Milligan, Peter ; Nock, Valerie ; Ramusovic, Sergej ; Riggs, Matthew ; Schaller, Stephan ; Schlender, Jan ; Schmidt, Stephan ; Sevestre, Michaël ; Sjögren, Erik ; Solodenko, Juri ; Staab, Alexander ; Teutonico, Donato
Publisher:United States: John Wiley & Sons, Inc
Journal title:CPT: pharmacometrics and systems pharmacology, 2019-12, Vol.8 (12), p.878-882
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ArticlesPeer ReviewedFull Text
The Clinical Pharmacokinetics of Phosphodiesterase-5 Inhibitors for Erectile Dysfunction
Author / Creator:Gupta, Manish ; Kovar, Andreas ; Meibohm, Bernd
Publisher:Oxford, UK: Blackwell Publishing Ltd
Journal title:Journal of clinical pharmacology, 2005-09, Vol.45 (9), p.987-1003
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ArticlesPeer ReviewedFull Text
LaTeX tutorial for the standardization and automation of population analysis reports
Author / Creator:Frank, Thomas ; Gastine, Silke ; Lindauer, Klaus ; Speth, Heiner ; Strougo, Ashley ; Kovar, Andreas
Publisher:United States: John Wiley & Sons, Inc
Journal title:CPT: pharmacometrics and systems pharmacology, 2021-11, Vol.10 (11), p.1310-1322
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ArticlesPeer ReviewedFull Text
A randomized multi-center phase II trial of the angiogenesis inhibitor Cilengitide (EMD 121974) and gemcitabine compared with gemcitabine alone in advanced unresectable pancreatic cancer
Author / Creator:Friess, Helmut ; Langrehr, Jan M ; Oettle, Helmut ; Raedle, Jochen ; Niedergethmann, Marco ; Dittrich, Christian ; Hossfeld, Dieter K ; Stöger, Herbert ; Neyns, Bart ; Herzog, Peter ; Piedbois, Pascal ; Dobrowolski, Frank ; Scheithauer, Werner ; Hawkins, Robert ; Katz, Frieder ; Balcke, Peter ; Vermorken, Jan ; van Belle, Simon ; Davidson, Neville ; Esteve, Albert Abad ; Castellano, Daniel ; Kleeff, Jörg ; Tempia-Caliera, Adrien A ; Kovar, Andreas ; Nippgen, Johannes
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2006-12, Vol.6 (1), p.285-285, Article 285
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ArticlesPeer ReviewedFull Text
Phase I/II open-label study of the biologic effects of the interleukin-2 immunocytokine EMD 273063 (hu14.18-IL2) in patients with metastatic malignant melanoma
Author / Creator:Ribas, Antoni ; Kirkwood, John M ; Atkins, Michael B ; Whiteside, Theresa L ; Gooding, William ; Kovar, Andreas ; Gillies, Stephen D ; Kashala, Oscar ; Morse, Michael A
Publisher:England: BioMed Central Ltd
Journal title:Journal of translational medicine, 2009-07, Vol.7 (1), p.68-68, Article 68
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ArticlesPeer ReviewedFull Text
Investigation of sarizotan's impact on the pharmacokinetics of probe drugs for major cytochrome P450 isoenzymes : A combined cocktail trial
Author / Creator:KRÖSSER, Sonja ; NEUGEBAUER, Roland ; DOLGOS, Hugues ; FLUCK, Markus ; ROST, Karl-Ludwig ; KOVAR, Andreas
Publisher:Heidelberg: Springer
Journal title:European journal of clinical pharmacology, 2006-04, Vol.62 (4), p.277-284
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ArticlesPeer ReviewedFull Text
Safety, tolerability, and pharmacokinetics of the novel αv-integrin antibody EMD 525797 (DI17E6) in healthy subjects after ascending single intravenous doses
Author / Creator:Uhl, Wolfgang ; Zühlsdorf, Michael ; Koernicke, Thomas ; Forssmann, Ulf ; Kovar, Andreas
Publisher:New York: Springer US
Journal title:Investigational new drugs, 2014-04, Vol.32 (2), p.347-354
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ArticlesPeer ReviewedFull Text
Population Pharmacokinetics of Cetuximab in Patients With Squamous Cell Carcinoma of the Head and Neck
Author / Creator:Dirks, Nathanae L. ; Nolting, Arno ; Kovar, Andreas ; Meibohm, Bernd
Publisher:Oxford, UK: Blackwell Publishing Ltd
Journal title:Journal of clinical pharmacology, 2008-03, Vol.48 (3), p.267-278
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ArticlesPeer ReviewedFull Text
Safety, tolerability, and pharmacokinetics of the novel [alpha]v-integrin antibody EMD 525797 (DI17E6) in healthy subjects after ascending single intravenous doses
Author / Creator:Uhl, Wolfgang ; Zühlsdorf, Michael ; Koernicke, Thomas ; ssmann, Ulf ; Kovar, Andreas
Publisher:New York: Springer Nature B.V
Journal title:Investigational new drugs, 2014-04, Vol.32 (2), p.347
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ArticlesPeer ReviewedFull Text
Refinement of the Population Pharmacokinetic Model for the Monoclonal Antibody Matuzumab: External Model Evaluation and Simulations
Author / Creator:Kuester, Katharina ; Kovar, Andreas ; Lüpfert, Christian ; Brockhaus, Brigitte ; Kloft, Charlotte
Publisher:Cham: Springer International Publishing
Journal title:Clinical pharmacokinetics, 2009-07, Vol.48 (7), p.477-487
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ArticlesPeer ReviewedFull Text
Clinical trial with escalating doses of the antiepidermal growth factor receptor humanized monoclonal antibody EMD 72 000 in patients with advanced squamous cell carcinoma of the larynx and hypopharyn...
Author / Creator:BIER, Henning ; HOFFMANN, Thomas ; HAUSER, Ulrich ; WINK, Michael ; ÖCHLER, Martin ; KOVAR, Andreas ; MÜSER, Matthias ; KNECHT, Reinald
Publisher:Berlin: Springer
Journal title:Cancer chemotherapy and pharmacology, 2001-06, Vol.47 (6), p.519-524
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ArticlesPeer ReviewedFull Text
Population Pharmacokinetics of Eniporide and Its Metabolite in Healthy Subjects and Patients With Acute Myocardial Infarction
Author / Creator:Bhattaram, Venkatesh Atul ; Nagaraja, Nelamangala V. ; Peters, Tanja ; Machnig, Thomas ; Kroesser, Sonja ; Kovar, Andreas ; Derendorf, Hartmut
Publisher:Oxford, UK: Blackwell Publishing Ltd
Journal title:Journal of clinical pharmacology, 2005-06, Vol.45 (6), p.631-639
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ArticlesFull Text
Comparison of the pharmacokinetics, safety and tolerability of two concentrations of a new liquid recombinant human growth hormone formulation versus the freeze-dried formulation
Author / Creator:Liedert, Bernd ; Forssmann, Ulf ; Wolna, Peter ; Golob, Michaela ; Kovar, Andreas
Publisher:England: BioMed Central Ltd
Journal title:BMC clinical pharmacology, 2010-10, Vol.10 (1), p.14-14, Article 14
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ArticlesPeer ReviewedFull Text
The Pharmacokinetic/Pharmacodynamic Research Tool (PRESTO): An Advanced Concept for Rational Drug Development
Author / Creator:Göller, Gernot ; Mück, Wolfgang ; Koss, Dieter ; Nörtersheuser, Peter ; Osswald, Michael ; Kovar, Andreas ; Zurth, Christian ; Poland, Hans
Publisher:Los Angeles, CA: SAGE Publications
Journal title:Therapeutic innovation & regulatory science, 2002, Vol.36 (1), p.57-66
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ReportsFull Text
Comparison of the pharmacokinetics, safety and tolerability of two concentrations of a new liquid recombinant human growth hormone formulation versus the freeze-dried formulation
Author / Creator:Liedert, Bernd ; Forssmann, Ulf ; Wolna, Peter ; Golob, Michaela ; Kovar, Andreas
Publisher:BioMed Central Ltd
Journal title:BMC Clinical Pharmacology, 2010, Vol.10, p.14
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Open Systems Pharmacology Community—An Open Access, Open Source, Open Science Approach to Modeling and Simulation in Pharmaceutical Sciences

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The Clinical Pharmacokinetics of Phosphodiesterase-5 Inhibitors for Erectile Dysfunction

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LaTeX tutorial for the standardization and automation of population analysis reports

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A randomized multi-center phase II trial of the angiogenesis inhibitor Cilengitide (EMD 121974) and gemcitabine compared with gemcitabine alone in advanced unresectable pancreatic cancer

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Phase I/II open-label study of the biologic effects of the interleukin-2 immunocytokine EMD 273063 (hu14.18-IL2) in patients with metastatic malignant melanoma

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Investigation of sarizotan's impact on the pharmacokinetics of probe drugs for major cytochrome P450 isoenzymes : A combined cocktail trial

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Safety, tolerability, and pharmacokinetics of the novel αv-integrin antibody EMD 525797 (DI17E6) in healthy subjects after ascending single intravenous doses

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Population Pharmacokinetics of Cetuximab in Patients With Squamous Cell Carcinoma of the Head and Neck

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Safety, tolerability, and pharmacokinetics of the novel [alpha]v-integrin antibody EMD 525797 (DI17E6) in healthy subjects after ascending single intravenous doses

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Refinement of the Population Pharmacokinetic Model for the Monoclonal Antibody Matuzumab: External Model Evaluation and Simulations

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Clinical trial with escalating doses of the antiepidermal growth factor receptor humanized monoclonal antibody EMD 72 000 in patients with advanced squamous cell carcinoma of the larynx and hypopharyn...

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Population Pharmacokinetics of Eniporide and Its Metabolite in Healthy Subjects and Patients With Acute Myocardial Infarction

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Comparison of the pharmacokinetics, safety and tolerability of two concentrations of a new liquid recombinant human growth hormone formulation versus the freeze-dried formulation

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The Pharmacokinetic/Pharmacodynamic Research Tool (PRESTO): An Advanced Concept for Rational Drug Development

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Comparison of the pharmacokinetics, safety and tolerability of two concentrations of a new liquid recombinant human growth hormone formulation versus the freeze-dried formulation

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